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THE GLOBAL EXISTENCE OF STRONG SOLUTIONS TO THERMOMECHANICAL CUCKER-SMALE-STOKES EQUATIONS IN THE WHOLE DOMAIN
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作者 邹委员 《Acta Mathematica Scientia》 SCIE CSCD 2024年第3期887-908,共22页
We study the global existence and uniqueness of a strong solution to the kinetic thermomechanical Cucker-Smale(for short,TCS) model coupled with Stokes equations in the whole space.The coupled system consists of the k... We study the global existence and uniqueness of a strong solution to the kinetic thermomechanical Cucker-Smale(for short,TCS) model coupled with Stokes equations in the whole space.The coupled system consists of the kinetic TCS equation for a particle ensemble and the Stokes equations for a fluid via a drag force.In this paper,we present a complete analysis of the existence of global-in-time strong solutions to the coupled model without any smallness restrictions on the initial data. 展开更多
关键词 thermomechanical Cucker-Smale model Stokes equations strong solutions global existence
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Existence of Entropy Solution for Degenerate Parabolic-Hyperbolic Problem Involving p(x)-Laplacian with Neumann Boundary Condition
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作者 Mohamed Karimou Gazibo Duni Yegbonoma Frédéric Zongo 《Applied Mathematics》 2024年第7期455-463,共9页
We consider a strongly non-linear degenerate parabolic-hyperbolic problem with p(x)-Laplacian diffusion flux function. We propose an entropy formulation and prove the existence of an entropy solution.
关键词 Lebesgue and Sobolev Spaces with Variable Exponent Weak Solution Entropy Solution Degenerate Parabolic-Hyperbolic Equation Conservation Law Leray Lions Type Operator Neumann Boundary Condition existence Result
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Global Existence and Decay of Solutions for a Class of a Pseudo-Parabolic Equation with Singular Potential and Logarithmic Nonlocal Source
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作者 Xiaoxin Yang 《Journal of Applied Mathematics and Physics》 2024年第1期181-193,共13页
This article investigates the well posedness and asymptotic behavior of Neumann initial boundary value problems for a class of pseudo-parabolic equations with singular potential and logarithmic nonlinearity. By utiliz... This article investigates the well posedness and asymptotic behavior of Neumann initial boundary value problems for a class of pseudo-parabolic equations with singular potential and logarithmic nonlinearity. By utilizing cut-off techniques and combining with the Faedo Galerkin approximation method, local solvability was established. Based on the potential well method and Hardy Sobolev inequality, derive the global existence of the solution. In addition, we also obtained the results of decay. 展开更多
关键词 Nonlocal Parabolic Equation Singular Potential Logarithmic Nonlocal Source Global existence DECAY
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Existence of Monotone Positive Solution for a Fourth-Order Three-Point BVP with Sign-Changing Green’s Function
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作者 Junrui Yue Yun Zhang Qingyue Bai 《Open Journal of Applied Sciences》 2024年第1期63-69,共7页
This paper is concerned with the following fourth-order three-point boundary value problem , where , we discuss the existence of positive solutions to the above problem by applying to the fixed point theory in cones a... This paper is concerned with the following fourth-order three-point boundary value problem , where , we discuss the existence of positive solutions to the above problem by applying to the fixed point theory in cones and iterative technique. 展开更多
关键词 Fourth-Order Three-Point Boundary Value Problem Sign-Changing Green’s Function Fixed Point Index Iterative Technique Monotone Positive Solution existence
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Existence of Solutions of a Convolution Integral Equation
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作者 Henry Otoo Benjamin Dadzie Mensah Lewis Brew 《Journal of Applied Mathematics and Physics》 2024年第5期1835-1847,共13页
In this study, we prove the of existence of solutions of a convolution Volterra integral equation in the space of the Lebesgue integrable function on the set of positive real numbers and with the standard norm defined... In this study, we prove the of existence of solutions of a convolution Volterra integral equation in the space of the Lebesgue integrable function on the set of positive real numbers and with the standard norm defined on it. An operator P was assigned to the convolution integral operator which was later expressed in terms of the superposition operator and the nonlinear operator. Given a ball B<sub>r</sub> belonging to the space L it was established that the operator P maps the ball into itself. The Hausdorff measure of noncompactness was then applied by first proving that given a set M∈ B r the set is bounded, closed, convex and nondecreasing. Finally, the Darbo fixed point theorem was applied on the measure obtained from the set E belonging to M. From this application, it was observed that the conditions for the Darbo fixed point theorem was satisfied. This indicated the presence of at least a fixed point for the integral equation which thereby implying the existence of solutions for the integral equation. 展开更多
关键词 VOLTERRA Integral Equation CONVOLUTION Fixed Point existence Noncompactness
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Global Existence of the Solution for a Reduced Model of the Vectorial Quantum Zakharov System
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作者 Guiyu Yang 《Journal of Applied Mathematics and Physics》 2024年第2期533-542,共10页
In this paper, we study the global existence of the smooth solution for a reduced quantum Zakharov system in two spatial dimensions. Using energy estimates and the logarithmic type Sobolev inequality, we show the glob... In this paper, we study the global existence of the smooth solution for a reduced quantum Zakharov system in two spatial dimensions. Using energy estimates and the logarithmic type Sobolev inequality, we show the global existence of the solution to this system without any small condition on the initial data. 展开更多
关键词 Quantum Zakharov System Global existence Logarithmic Sobolev Inequality
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THE EXISTENCE OF GLOBAL SOLUTIONS FOR THE FULL NAVIER-STOKES-KORTEWEG SYSTEM OF VAN DER WAALS GAS
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作者 Hakho HONG 《Acta Mathematica Scientia》 SCIE CSCD 2023年第2期469-491,共23页
The aim of this work is to prove the existence for the global solution of a nonisothermal or non-isentropic model of capillary compressible fluids derived by J.E.Dunn and J.Serrin(1985),in the case of van der Waals ga... The aim of this work is to prove the existence for the global solution of a nonisothermal or non-isentropic model of capillary compressible fluids derived by J.E.Dunn and J.Serrin(1985),in the case of van der Waals gas.Under the small initial perturbation,the proof of the global existence is based on an elementary energy method using the continuation argument of local solution.Moreover,the uniqueness of global solutions and large time behavior of the density are given.It is one of the main difficulties that the pressure p is not the increasing function of the densityρ. 展开更多
关键词 Navier-Stokes-Korteweg system van der Waals gas existence UNIQUENESS
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The existence of radial k-admissible solutions for n-dimension system of k-Hessian equations
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作者 HE Xing-yue WANG Jing-jing GAO Cheng-hua 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2023年第2期310-316,共7页
In this paper,we focus on a general n-dimension system of k-Hessian equations.By introducing some new suitable growth conditions,the existence results of radial k-admissible solutions of the k-Hessian system are obtai... In this paper,we focus on a general n-dimension system of k-Hessian equations.By introducing some new suitable growth conditions,the existence results of radial k-admissible solutions of the k-Hessian system are obtained.Our approach is largely based on the well-known fixed-point theorem. 展开更多
关键词 k-Hessian equations radial k-admissible solutions existence xed-point theorem
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THE EXISTENCE AND MULTIPLICITY OF k-CONVEX SOLUTIONS FOR A COUPLED k-HESSIAN SYSTEM
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作者 高承华 何兴玥 王晶晶 《Acta Mathematica Scientia》 SCIE CSCD 2023年第6期2615-2628,共14页
In this paper,we focus on the following coupled system of k-Hessian equations:{S_(k)(λ(D^(2)u))=f_(1)(|x|,-v)in B,S_(k)(λ(D^(2)v))=f2(|x|,-u)in B,u=v=0 on■B.Here B is a unit ball with center 0 and fi(i=1,2)are cont... In this paper,we focus on the following coupled system of k-Hessian equations:{S_(k)(λ(D^(2)u))=f_(1)(|x|,-v)in B,S_(k)(λ(D^(2)v))=f2(|x|,-u)in B,u=v=0 on■B.Here B is a unit ball with center 0 and fi(i=1,2)are continuous and nonnegative functions.By introducing some new growth conditions on the nonlinearities f_(1) and f_(2),which are more flexible than the existing conditions for the k-Hessian systems(equations),several new existence and multiplicity results for k-convex solutions for this kind of problem are obtained. 展开更多
关键词 system of k-Hessian equations k-convex solutions existence MULTIPLICITY fixed-point theorem
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Effect of existence state of asphaltenes on the asphaltenes-wax interaction in wax deposition
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作者 Yun Lei Han Wang +5 位作者 Shuang-Shuang Li Xue-Qian Liu Hao-Ran Zhu Yu-Ming Gao Hao-Ping Peng Peng-Fei Yu 《Petroleum Science》 SCIE EI CAS CSCD 2023年第1期507-514,共8页
Asphaltenes are the most elusive substances in waxy crude oil,especially the complex structures,which leads to significant precipitation and aggregation characteristics of asphaltenes,and affects the asphaltenes-wax i... Asphaltenes are the most elusive substances in waxy crude oil,especially the complex structures,which leads to significant precipitation and aggregation characteristics of asphaltenes,and affects the asphaltenes-wax interaction.In this study,the concept of the existence state of asphaltenes was introduced to semi-quantitatively investigate the precipitation and aggregation characteristics of asphaltenes.On this basis,the influence of the existence state of asphaltenes on wax deposition was studied by coldfinger device and high-temperature gas chromatography,and the composition and properties of the deposits were analyzed.Four main findings were made:(1)As the asphaltene concentration increases,the existence state of asphaltenes gradually transitions from dispersed state to aggregated state,and the asphaltene concentration of 0.30 wt%in this study is the starting point of the transition.(2)The existence state of asphaltenes in crude oil does affect the process of wax deposition,as shown in the fact that the dispersed asphaltenes promote the occurrence of wax deposition,while the aggregated asphaltenes can inhibit wax deposition.(3)In the presence of the aggregated asphaltenes,that is,when the asphaltene concentration is higher than 0.30 wt%,the shedding phenomenon of deposit layer was observed,and with the increase of aggregated asphaltenes,the deposit layer fell off earlier.(4)With the increase of the dispersed asphaltenes,the wax appearance temperature(WAT)and wax content of the deposits all showed an increasing trend,while with the appearance of the aggregated asphaltenes,the above situation was reversed.The findings of this study can help for better understanding of the interaction between the asphaltenes and wax in wax deposition. 展开更多
关键词 ASPHALTENES Precipitation/aggregation existence state of asphaltenes Deposition
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Existence and Uniqueness Results for a Fully Third-Order Boundary Value Problem
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作者 Xiaoming Liu Yongxiang Li 《Advances in Pure Mathematics》 2023年第8期495-503,共14页
The boundary value problems of the third-order ordinary differential equation have many practical application backgrounds and their some special cases have been studied by many authors. However, few scholars have stud... The boundary value problems of the third-order ordinary differential equation have many practical application backgrounds and their some special cases have been studied by many authors. However, few scholars have studied the boundary value problems of the complete third-order differential equations u′′′(t) = f (t,u(t),u′(t),u′′(t)). In this paper, we discuss the existence and uniqueness of solutions and positive solutions of the fully third-order ordinary differential equation on [0,1] with the boundary condition u(0) = u′(1) = u′′(1) = 0. Under some inequality conditions on nonlinearity f some new existence and uniqueness results of solutions and positive solutions are obtained. 展开更多
关键词 Fully Third-Order BVP SOLUTION Positive Solution existence and Uniqueness Inequality Conditions
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Existence and Stability of Solutions for a Class of Fractional Impulsive Differential Equations with Atangana-Baleanu-Caputo Derivative
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作者 Xuefan Lin Weimin Hu +1 位作者 Youhui Su Yongzhen Yun 《Journal of Applied Mathematics and Physics》 2023年第12期3914-3927,共14页
In this paper, we are concerned with the existence of solutions to a class of Atangana-Baleanu-Caputo impulsive fractional differential equation. The existence and uniqueness of the solution of the fractional differen... In this paper, we are concerned with the existence of solutions to a class of Atangana-Baleanu-Caputo impulsive fractional differential equation. The existence and uniqueness of the solution of the fractional differential equation are obtained by Banach and Krasnoselakii fixed point theorems, and sufficient conditions for the existence and uniqueness of the solution are also developed. In addition, the Hyers-Ulam stability of the solution is considered. At last, an example is given to illustrate the main results. 展开更多
关键词 Fractional Differential Equation Fixed Point Theorem existence of Solutions
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SUFFICIENT AND NECESSARY CONDITIONS ON THE EXISTENCE AND ESTIMATES OF BOUNDARY BLOW-UP SOLUTIONS FOR SINGULAR p-LAPLACIAN EQUATIONS
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作者 张学梅 阚士坤 《Acta Mathematica Scientia》 SCIE CSCD 2023年第3期1175-1194,共20页
Let?denote a smooth,bounded domain in R^(N)(N≥2).Suppose that g is a nondecreasing C^(1)positive function and assume that b(x)is continuous and nonnegative inΩ,and that it may be singular on■Ω.In this paper,we pro... Let?denote a smooth,bounded domain in R^(N)(N≥2).Suppose that g is a nondecreasing C^(1)positive function and assume that b(x)is continuous and nonnegative inΩ,and that it may be singular on■Ω.In this paper,we provide sufficient and necessary conditions on the existence of boundary blow-up solutions to the p-Laplacian problem△_(p)u=b(x)g(u)for x∈Ω,u(x)→+∞as dist(x,■Ω)→0.The estimates of such solutions are also investigated.Moreover,when b has strong singularity,the nonexistence of boundary blow-up(radial)solutions and infinitely many radial solutions are also considered. 展开更多
关键词 singular p-Laplacian equation boundary blow-up sub-supersolution method existence nonexistence and estimates sufficient and necessary conditions
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THE EXISTENCE AND LOCAL UNIQUENESS OF MULTI-PEAK SOLUTIONS TO A CLASS OF KIRCHHOFF TYPE EQUATIONS
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作者 崔磊磊 郭佳星 李工宝 《Acta Mathematica Scientia》 SCIE CSCD 2023年第3期1131-1160,共30页
In this paper,we study the existence and local uniqueness of multi-peak solutions to the Kirchhoff type equations-(ε^(2)a+εb∫_(R^(3))|■u|^(2))△u+V(x)u=u^(p),u>0 in R^(3),which concentrate at non-degenerate cri... In this paper,we study the existence and local uniqueness of multi-peak solutions to the Kirchhoff type equations-(ε^(2)a+εb∫_(R^(3))|■u|^(2))△u+V(x)u=u^(p),u>0 in R^(3),which concentrate at non-degenerate critical points of the potential function V(x),where a,b>0,1<p<5 are constants,andε>0 is a parameter.Applying the Lyapunov-Schmidt reduction method and a local Pohozaev type identity,we establish the existence and local uniqueness results of multi-peak solutions,which concentrate at{a_(i)}1≤i≤k,where{a_(i)}1≤i≤k are non-degenerate critical points of V(x)asε→0. 展开更多
关键词 Kirchhoff type equations potential functions having non-degenerate critical points the Lyapunov-Schmidt reduction method multi-peak solutions existence and local uniqueness
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水资源-能源-粮食-生态系统耦合协调及驱动力分析 被引量:1
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作者 杨明明 朱永楠 +2 位作者 赵勇 杨文静 樊煜 《人民黄河》 CAS 北大核心 2024年第3期58-63,共6页
为加深对我国水资源、能源、粮食、生态系统协同演变趋势的认识,构建水资源-能源-粮食-生态多维系统指标体系,运用耦合协调度模型对我国2005—2020年水资源-能源-粮食-生态系统耦合协调度进行评价,并采用多因素归因分析法进行驱动力分... 为加深对我国水资源、能源、粮食、生态系统协同演变趋势的认识,构建水资源-能源-粮食-生态多维系统指标体系,运用耦合协调度模型对我国2005—2020年水资源-能源-粮食-生态系统耦合协调度进行评价,并采用多因素归因分析法进行驱动力分析。结果表明:我国水资源-能源-粮食-生态系统耦合协调度从2005年的0.55增长到2020年的0.84,各地区耦合协调度从勉强协调发展水平过渡到中级协调发展水平,各子系统对耦合协调度上升的驱动分别经历了由粮食子系统到生态子系统再到水资源子系统主导的过程;能源子系统的贡献率虽然比较小,但是未来可能是各地区提升水资源-能源-粮食-生态系统多维系统协调发展水平的突破口。 展开更多
关键词 水资源-能源-粮食-生态 耦合协调度 多因素归因分析 驱动力
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基于DEMATEL-ISM的水利工程EPC项目价值增值机理研究 被引量:1
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作者 俞洪良 杨正涵 +1 位作者 徐铨彪 潘益斌 《浙江大学学报(理学版)》 CAS CSCD 北大核心 2024年第1期120-130,共11页
采用设计-采购-施工(engineering-procurement-construction,EPC)总承包模式的水利工程项目日益增多,研究其价值增值机理有利于总承包方做好项目的价值管理。从水利工程EPC项目的价值链分析入手,基于文献和专家访谈得到23个价值增值影... 采用设计-采购-施工(engineering-procurement-construction,EPC)总承包模式的水利工程项目日益增多,研究其价值增值机理有利于总承包方做好项目的价值管理。从水利工程EPC项目的价值链分析入手,基于文献和专家访谈得到23个价值增值影响因素。采用问卷调查方式得到各因素间的影响程度评分,用决策实验和评估实验(decision-making trial and evaluation laboratory,DEMATEL)法计算了各因素的中心度和原因度,结合解释结构模型(interpretative structural modeling,ISM)对数据进行分析,将价值增值因素划分为6类,构建了水利工程EPC项目价值增值的递阶模型,探究和揭示了项目价值增值的路径和机理。研究结果对水利工程EPC总承包方制订管理策略有一定启示作用。 展开更多
关键词 水利工程 设计-采购-施工(EPC)总承包 价值增值 决策实验和评估实验-解释结构模型(DEMATEL-SIM)
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二氧化碳-水-岩作用机理及微观模拟方法研究进展 被引量:2
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作者 张烈辉 张涛 +6 位作者 赵玉龙 胡浩然 文绍牧 吴建发 曹成 汪永朝 范云婷 《石油勘探与开发》 EI CSCD 北大核心 2024年第1期199-211,共13页
系统综述CO_(2)-水-岩复杂作用机理、多孔介质反应输运(溶解、沉淀及沉淀运移)微观模拟、CO_(2)-水-岩系统微观模拟3个方面的研究进展,指出目前研究存在的主要问题并提出了关于未来研究方向的建议。CO_(2)注入储集层后,不仅存在常规渗... 系统综述CO_(2)-水-岩复杂作用机理、多孔介质反应输运(溶解、沉淀及沉淀运移)微观模拟、CO_(2)-水-岩系统微观模拟3个方面的研究进展,指出目前研究存在的主要问题并提出了关于未来研究方向的建议。CO_(2)注入储集层后,不仅存在常规渗流体系的流动和传质作用,还会产生溶解、沉淀及沉淀运移等特殊物理化学现象,其耦合作用导致多孔介质的孔渗参数变化规律复杂。孔隙尺度的微观渗流模拟,可以得到孔喉三维空间内的详细信息,且能显性观察到多孔介质流-固界面随反应的变化。目前研究主要在复杂作用机理解耦合、多矿物差异性反应表征、沉淀生成机理及表征(晶体成核和矿物脱落)、沉淀-流体相互作用模拟方法、多物理化学过程耦合渗流机制等方面存在局限。未来研究中,需要创新实验方法对“溶解—沉淀—沉淀运移”解耦合,提高矿物地球化学反应相关参数实验测试的准确度,在不同沉淀机理可靠表征的基础上,建立沉淀-流体相互作用模拟方法,并有机耦合各个物理化学过程,最终实现对CO_(2)-水-岩系统中“溶解—沉淀—沉淀运移”的耦合渗流模拟。 展开更多
关键词 CO_(2)--岩系统 溶解 沉淀 沉淀运移 微观模拟 CO_(2)捕集、利用与埋存 碳中和 解耦合
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基于GC-IMS和GC-MS技术结合化学计量法分析干燥方式对香椿挥发性成分的影响 被引量:1
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作者 张乐 魏依馨 +5 位作者 史冠莹 蒋鹏飞 赵丽丽 王继红 张少南 王赵改 《食品工业科技》 CAS 北大核心 2024年第11期222-234,共13页
为研究干燥方式对香椿挥发性风味物质的影响,利用气相色谱-离子迁移谱技术(gaschromatography-ion mobility spectrometry,GC-IMS)和气相色谱-质谱联用技术(gas chromatography-mass spectrometry,GC-MS)、相对香气活性值(relative odor... 为研究干燥方式对香椿挥发性风味物质的影响,利用气相色谱-离子迁移谱技术(gaschromatography-ion mobility spectrometry,GC-IMS)和气相色谱-质谱联用技术(gas chromatography-mass spectrometry,GC-MS)、相对香气活性值(relative odor activity value,ROAV)对真空冷冻干燥、热泵干燥、热风干燥、微波真空干燥的香椿样品进行挥发性成分分析,并进一步结合化学计量方法主成分分析(principal component analysis,PCA)和偏最小二乘判别分析(partial least squares-discriminant analysis,PLS-DA),探究样品间挥发性成分的差异性。结果表明,通过GC-IMS检测到78个峰,鉴定出59种化合物。通过GC-MS鉴定出94种挥发性化合物,主要挥发性成分是硫化物、烯烃类和醛类。经过干燥后总挥发性化合物的含量显著降低。通过ROAV法确定了(E,Z)-二-1-丙烯基二硫化物、2-巯基-3,4-二甲基-2,3-二氢噻吩、正己醛、2-己烯醛、丁香酚等为香椿样品中关键香气化合物。PCA和PLS-DA结果表明,不同干燥方式的样品与新鲜样品有明显的分离,彼此之间也有明显的区别。鲜样和真空冷冻干燥样品为一组,其他3个干燥香椿样品为一组。根据变量投影重要性(variable importance in projection,VIP)得分共筛选出10种(VIP>1)标志挥发性化合物。干燥方式对香椿风味特性影响显著,真空冷冻干燥组与鲜样最为接近,考虑实际应用热泵干燥为香椿最适宜的脱水方式。本研究为热加工过程中风味品质控制提供一定的理论参考。 展开更多
关键词 香椿 干燥方式 气相色谱-离子迁移谱(GC-IMS) 气相色谱-质谱联用技术(GC-MS) 挥发性化合物
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基于CFD-DEM的流-固耦合数值建模方法研究进展 被引量:3
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作者 蔡国庆 刁显锋 +3 位作者 杨芮 王北辰 高帅 刘韬 《哈尔滨工业大学学报》 EI CAS CSCD 北大核心 2024年第1期17-32,共16页
随着土体渗流侵蚀研究的逐渐深入,对土颗粒流失和变形破坏机理的研究方法呈现出多尺度的特点。其中,计算流体力学-离散元耦合方法(CFD-DEM)为在细观尺度上研究流-固耦合相互作用对土体宏观力学特性的影响提供了一种行之有效的方法。针对... 随着土体渗流侵蚀研究的逐渐深入,对土颗粒流失和变形破坏机理的研究方法呈现出多尺度的特点。其中,计算流体力学-离散元耦合方法(CFD-DEM)为在细观尺度上研究流-固耦合相互作用对土体宏观力学特性的影响提供了一种行之有效的方法。针对CFD-DEM耦合方法在岩土工程领域应用现状,本文系统总结现有流-固耦合计算方法的优缺点,重点论述CFD-DEM耦合方法的建模策略,包括固相颗粒形状建模与粒间接触模型、流体相控制方程及参数计算方法,以及CFD-DEM耦合计算,并就相关问题进行深入探讨,最后提出了CFD-DEM耦合方法未来的发展方向。 展开更多
关键词 CFD-DEM -固耦合 颗粒建模 流体建模 -固相互作用力
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老年急性脑梗死患者血清Del-1和IL-17水平变化及与梗死面积和预后的关系 被引量:1
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作者 郑德泉 江华 +4 位作者 韩玉惠 杨青平 吴义森 欧阳林 李清金 《中国实用神经疾病杂志》 2024年第1期26-30,共5页
目的 探究老年急性脑梗死(ACI)患者血清内皮发育调节基因-1(Del-1)、白细胞介素-17(IL-17)水平与脑梗死面积、病情严重程度及预后的关系。方法 回顾性收集2019-01-2021-12厦门大学附属东南医院收治的126例老年ACI患者(病例组)及105名健... 目的 探究老年急性脑梗死(ACI)患者血清内皮发育调节基因-1(Del-1)、白细胞介素-17(IL-17)水平与脑梗死面积、病情严重程度及预后的关系。方法 回顾性收集2019-01-2021-12厦门大学附属东南医院收治的126例老年ACI患者(病例组)及105名健康体检者(对照组)的临床资料,根据脑梗死面积将病例组患者分为大面积梗死组(梗死最大直径>5 cm,n=14)、中面积梗死组(梗死最大直径3~5 cm,n=53)和小面积梗死组(梗死最大直径<3 cm,n=59);根据NIHSS评分分为重症组(NIHSS评分≥16分,n=13)、中症组(5分<NIHSS评分<15分,n=58)和轻症组(NIHSS评分≤5分,n=55);根据m RS评分分为预后良好组(mRS评分≤2分,n=81)和预后不良组(mRS评分>2分,n=45)。采用荧光免疫法检测血清Del-1、IL-17水平,受试者工作特征(ROC)曲线评估血清Del-1、IL-17水平预测老年ACI患者预后的价值。结果 病例组吸烟史比例、收缩压、舒张压、糖化血红蛋白、血清IL-17水平均高于对照组,血清Del-1水平低于对照组(P<0.05)。不同脑梗死面积患者血清Del-1水平比较,小面积梗死组>中面积梗死组>大面积梗死组;血清IL-17水平比较,小面积梗死组<中面积梗死组<大面积梗死组(P<0.05)。轻症组血清Del-1水平高于中症组、重症组(P<0.05),不同病情严重程度患者血清IL-17水平比较,重症组>中症组>轻症组(P<0.05)。预后良好组患者血清Del-1水平高于预后不良组,血清IL-17水平低于预后不良组(P<0.05)。ROC曲线分析显示,血清Del-1、IL-17预测ACI患者预后的AUC值分别为0.763、0.747(P<0.05)。结论 老年ACI患者血清Del-1水平较低,IL-17水平较高,二者与患者脑梗死面积、病情严重程度和预后关系密切,可作为预测老年ACI患者预后的可靠指标。 展开更多
关键词 急性脑梗死 内皮发育调节基因-1 白细胞介素-17 梗死面积 预后 危险因素 血清
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