Suggestions for Promoting China’s Drug Regulatory Agency to Join Pharmaceutical Inspection Co-operation Scheme-PIC/S

Objective To identify and reduce the gap between China’s drug GMP inspection and pharmaceutical inspection co-operation scheme(PIC/S)audit checklist,find out the key improvement items,and revise them pertinently,which will promote the process of China joining PIC/S.Methods The general situation of PIC/S organization and audit checklist were introduced first,and then the accession of several countries that joined the organization was analyzed.Meanwhile,the process of China’s participation in PIC/S was sorted out.After referring to the contents of PIC/S audit checklist,the problems of GMP inspection system in China were studied.Results and Conclusion There are still many problems in GMP inspection in China.Some suggestions are put forward for improvement and change,which can provide reference for the development of drug inspection agencies at all levels in China.

A novel model for extending international co-operation in science and education

In September 1994 the University of Twente, the Netherlands, and Zhejiang University, China, decided to cooperate in the field of science, education and management. After several visits of delegations from both sides it was considered worthwhile to explore further opportunities for mutual cooperation. The directors of international cooperation on each side jointly commissioned a project to investigate the potential in a systematic way and to establish further contacts where appropriate. This paper reports on the results of the research cum matching project. To reveal promising matches between multiple departments of both academic institutions a matching model for uni-versities was designed. The study was carried out along two parallel lines. In the research line the theoretical framework was developed into a model for international university co-operation. Moreover, an analysis was carried out on internal, external and cultural aspects resulting in a set of thirty four influencing factors. In the matching line a total of seventy interviews were held in order to identify promising matches between units at both universities. This line resulted in eleven promising matches for further co-operation. The novel model appeared useful in analyzing the variety of factors and in developing matches between both univer-sities. In the further implementation of the model the issues of 搇evel of co-operation?and 搕op-down versus bottom-up?need to be addressed in more detail.

Co-operation on The Roof of the World

A freezing wind sweeps through the narrow Tibetan valley,whistling over the sand,stones and dry grass,buffeting the grazing sheep and the low houses of the tiny village which nestles there at an altitude of 4,600 meters.High overhead white clouds scud across skies of an unimaginably intense cobalt blue.Towards the south,the glistening peak of Everest rises momentarily from amidst the bank of clouds which hover over the barren ochre slopes already in autumnal garb and heralding the onset of winter.The farmers have been busy gathering

A review of science–policy interface for water governance in the Caspian Sea

Science and policy have been interlinked for decades and perform essential nexus conditions in the governing aspects of environmental scenarios.This review paper examines the present challenges in the science–policy interface in terms of water governance in the Caspian Sea and identifies effective conditions that may be used in the current context to enhance the mechanism.The evaluation of the science–policy link in the water policy of the Caspian Sea reveals a gap between knowledge producer and governance system,impeding the translation of scientific information into action.Complicated and context-dependent solutions make it challenging to establish effective science–policy processes in the Caspian Sea water governance settings.Establishing a common governing authority,implementing water and resource management regulations,and protecting the natural environment through legal frameworks are crucial steps to address these concerns and ensure sustainable development.Collaboration among coastal states is essential in environmental,economic,and social aspects of regional development.However,the lack of a comprehensive approach,coherent activities,and effective utilization of national and regional power has hindered efforts to halt the environmental degradation of the Caspian Sea.Local governments need to recognize their responsibility to protect and utilize the Caspian Sea for present and future generations,considering both environmental and human security.The interlinkage of the Caspian Sea water governance with the Organization for Economic Co-operation and Development(OECD)water governance principles offers a framework for policymakers to assess gaps and make necessary amendments to existing mechanisms.Effective science–policy interaction,engagement of diverse stakeholders,institutionalizing agreements,and addressing collective action issues are critical for successful water governance.

Is there regional convergence between Morocco and its OECD partner countries in terms of well-being?

Morocco wants its 12 regions to play the role as the main lever of its public policies to initiate harmonized spatial multidimensional development. In the context of this goal and Morocco’s openness over the past two decades to bilateral and multilateral cooperation in an effort toward regional integration, this article studies the convergence of 389 regions in 36 countries(Morocco and 35 of its partner member countries in the Organization for Economic Co-operation and Development(OECD)) between 2000 and 2019 in terms of well-being. To this end, we considered the territorial dimension of β-convergence models for well-being and its four domains(economic, social, environmental, and governance). Then, we adapted the absolute β-convergence model by taking into account the existence of spatial heterogeneity according to five specifications of spatial models. Thus, apart from environmental domain, we found that β-convergence of regions is significant for well-being and three of its domains(economic, social, and governance). These convergences are made by a spatially autocorrelated error model(SEM). However, the speed and period of convergence are relatively low for social domain, partly explaining the very exacerbated tensions at the territorial level. The fastest convergence was achieved in governance domain, followed by economic domain. This suggests that emerging countries must pay particular attention to national public action in favor of social cohesion at the territorial level. The lack of convergence in environmental domain calls for common actions for all countries at the supranational level to protect the commons at the territorial level.

Conflicts and Countermeasures between Haba Snow Mountain Nature Reserve and Development of Peripheral Communities

Using research approaches such as questionnaire investigation, interview, and Participatory Rural Appraisal (PAR), the relationship between Haba Snow Mountain Nature Reserve and peripheral communities was studied. The results showed that there are lots of conflicts between Haba Snow Mountain Nature Reserve and peripheral communities. On the one hand, conservation of natural environment brings inconvenience to the development of peripheral communities, such as limiting the use of resources, constraining space of development, resulting in economic losses, reducing tourist income, and low compensation. On the other hand, peripheral communities' development threats conservation of the natural environment, for instance, illegal deforestation, illegal mining, over-harvesting, over-grazing and non-ecotourism. Therefore, effective suggestions were given as "scientific planning of functional areas, enhancing economic compensation, devoting more in ecotourism development, and realizing the cooperation of communities".

PBCL在数学建模教学中的实践与思考

PBCL是将"以问题为中心"的学习和合作学习整合在一起的一种新型教学模式,能够很好地促进学生独立思考,提高分析、解决实际问题的能力,培养学生的合作意识。

Role of nurses in improving patient safety: Evidence from surgical complications in 21 countries

Objectives: To analyze the role of nurse staffing in improving patient safety due to reducing surgical complications in member countries of Organization for Economic Co-operation and Development (OECD).Methods: The number of practicing nurses' density per 1000 population and five surgical complications indicators including foreign body left in during procedure (FBL),postoperative pulmonary embolism (PPE) and deep vein thrombosis (DVT) after hip and knee replacement,postoperative sepsis after abdominal surgery (PSA) and postoperative wound dehiscence (PWD) were collected in crude rates per 100,000 hospital discharges for age group of 15 years old and over within 30 days after surgery based on surgical admission-related and all admission-related methods.The observations of 21 OECD countries were collected from OECD Health Statistics during 2010-2015 period.The statistical technique of panel data analysis including unit root test,co-integration test and dynamic long-run analysis were used to estimate the possible relationship between our panel series.Results: There were significant relationships from nurse-staffing level to reducing FBL,PPE,DVT,PSA and PWD with long-run magnitudes of-2.91,-1.30,-1.69,-2.81 and-1.12 based on surgical admission method as well as-6.12,-14.57,-7.29,-1.41 and-0.88 based on all admission method,respectively.Conclusions: A higher proportion of nurses is associated with higher patient safety resulting from lower surgical complications and adverse clinical outcomes in OECD countries.Hence,we alert policy makers about the risk of underestimating the impact of nurses on improving patient safety as well as the quality of health care services in OECD countries.

Update on Fengyun Meteorological Satellite Program and Development

China began to develop its meteorological satellite program since 1969.With 50-years’growing,there are 17 Fengyun(FY)meteorological satellites launched successfully.At present,seven of them are in orbit to provide the operational service,including three polar orbiting meteorological satellites and four geostationary meteorological satellites.Since last COSPAR report,no new Fengyun satellite has been launched.The information of the on-orbit FY-2 series,FY-3 series,and FY-4 series has been updated.FY-3D and FY-2H satellites accomplished the commission test and transitioned into operation in 2018.FY-2E satellite completed its service to decommission in 2019.The web-based users and Direct Broadcasting(DB)users keep growing worldwide to require the Fengyun satellite data and products.A new Mobile Application Service has been launched to Fengyun users based on the cloud technology in 2018.In this report,the international and regional co-operations to facilitate the Fengyun user community have been addressed especially.To strengthen the data service in the Belt and Road countries,the Emergency Support Mechanism of Fengyun satellite(FY_ESM)has been established since 2018.Meanwhile,a Recalibrating 30-years’archived Fengyun satellite data project has been founded since 2018.This project targets to generate the Fundamental Climate Data Record(FCDR)as a space agency response to the Global Climate Observation System(GCOS).At last,the future Fengyun program up to 2025 has been introduced as well.

Nurse staffing and life expectancy at birth and at 65 years old:Evidence from 35 OECD countries

Objective: To measure the possible magnitude of the role nurse staffing has on increasing life expectancy at birth and at 65 years old.Methods: The statistical technique of panel data analysis was applied to investigate the relationship from the number of practicing nurses' density per 1000 population to life expectancy at birth and at 65 years old.Five control variables were used as the proxies for the levels of medical staffing,health care financial and physical resources,and medical technology.The observations of 35 member countries of Organization for Economic Co-operation and Development (OECD) were collected from OECD Health Statistics over 2000-2016 period.Results: There were meaningful relationships from nurse staffing to life expectancy at birth and at 65 years with the long-run elasticities of 0.02 and 0.08,respectively.Overall,the role of nursing characteristics in increasing life expectancy indicators varied among different health care systems of OECD countries and in average were determined at the highest level in Japan (0.25),followed by Iceland (0.24),Belgium (0.21),Czech Republic (0.21),Slovenia (0.20) and Sweden (0.18).Conclusion: A higher proportion of nursing staff is associated with higher life expectancy in OECD countries and the dependency of life expectancy to nursing staff would increase by aging.Hence,the findings of this study warn health policy makers about ignoring the effects nursing shortages create e.g.increasing the risk of actual age-specific mortality,especially in care of elderly people.

Progress of Fengyun Meteorological Satellites Since 2020

China’s efforts to develop Fengyun meteorological satellites have made major strides over the past 50 years,with the polar and geostationary meteorological satellite series achieving continuously stable operation to persistently provide data and product services globally.By the end of 2021,19 Chinese self-developed Fengyun meteorological satellites have been launched successfully.Seven of them are in operation at present,the data and products are widely applied to weather analysis,numerical weather forecasting and climate prediction,as well as environment and disaster monitoring.Since the last COSPAR report,FY-4B,the first new-generation operational geostationary satellite,and FY-3E,the first early-morning orbit satellite in China’s polar-orbiting meteorological satellite family have been launched in 2021.The characteristics of the two latest satellites and the instruments onboard are addressed in this report.The status of current Fengyun Satellites,product and data service and international cooperation and supporting activities has been introduced as well.

Analyzing economic feasibility for investing in nursing care: Evidence from panel data analysis in 35 OECD countries

Objective:To analyze economic feasibility for investing in nursing care.Method:The number of practicing nurses'density per 1000 population as a proxy for nursing staff and Gross Domestic Product(GDP)per capita(current US$)were collected in 35 member countries of Organization for Economic Co-operation and Development(OECD)over 2000-2016 period.The statistical technique of panel data analysis including unit root test,cointegration analysis,Granger causality test,dynamic long-run model analysis and error correction model were applied to measure economic impact of nursing-related services.Results:There was a committed bilateral relationship between nurse-staffing level and GDP with longrun magnitudes of 1.39 and 0A1 for GDP-lead-nurse and nurse-lead-GDP directions in OECD countries,respectively.Moreover,the highest long-run magnitudes of the effect nursing staff has on increasing GDP per capita were calculated in Finland(2.07),Sweden(1.92),Estonia(1.68),Poland(1.52),Czech Republic(1.48),Norway(1.47)and Canada(1.24).Conclusion:Our findings verify that although the dependency of nursing characteristics to GDP per capita is higher than the reliance of GDP to number of nurses'density per 1000 population,investing in nursing care is economically feasible in OECD countries i.e.nursing is not only a financial burden(or cost)on health care systems,but also an economic stimulus in OECD countries.Hence,we alert governments and policy makers about the risk of underestimating the economic impacts of nurses on economic systems of OECD countries.

Impact of nurse staffing on reducing infant, neonatal and perinatal mortality rates: Evidence from panel data analysis in 35 OECD countries

Objectives:To investigate the magnitude of effect nurse staffing had on decreasing the newborn mortality rates in member countries of Organisation for Economic Co-operation and Development(OECD).Methods:The statistical technique of panel data analysis was applied to explore the possibility of association between the number of nurses'density per 1,000 population and infant,neonatal and perinatal mortality rates(IMR,NMR and PMR)per 1000 births.The observations of 35 OECD countries were collected over the period of 2000 through 2016.Results:There were significant associations between nurse staffing and IMR,NMR and PMR i.e.a 1%increase in nurse-staffing level reduced IMR,NMR and PMR by 0.98%,0.97%and 0.96%,respectively.Furthermore,the role of nursing-related services in declining the average of newborn mortality rates were investigated at the highest level in Slovenia(-5.50),Sweden(-3.34),Iceland(-2.51),Czech Republic(-1.86),Japan(-1.64)and Finland(-1.64).Moreover,if the current relationship between nursestaffing level and newborn mortality rates are disturbed with nursing shortage(e.g.in Slovak Republic and Israel),then it takes about 17 years for the mortality rates to reduce and restore back to the previous equilibrium.Conclusions:A higher proportion of nurses'density per 1,000 population is associated with lower newborn mortality rates.In addition,the nursing-related services of Slovenia,Sweden,Iceland,Czech Republic,Japan and Finland with the highest impact on improving the health level of newborns would be good patterns for other developed countries in maternity and child health care.

Malaysia＇s Contemporary Political and Economic Relations with Iran

Traditionally, Malaysia＇s relations with the Middle Eastern World boil down to narrow-limited interaction with only a handful of countries, mainly Egypt, Saudi Arabia （before known as Hejaz）, and Turkey. The underlying reasons behind are largely owing to the established ancient relations and religious fulfillments like performing pilgrimage as well as pursuing religious studies in highly respected institutions. Malaysia＇s relation with the Islamic Republic of Iran, however, has shown steady progress of development since the end of 1960s and onwards. Although Iran has become an Islamic Republic after the eruption of the Revolution in 1979, the relations remain intact in spite of the potential expansion of Iran＇s religious ideology, Shi＇ah, among Malaysian Muslim communities. On top of that, with Iran now facing economic sanctions due to its nuclear programs, both countries continue to bolster their relations, especially in political and economic interactions. Contemporarily, both Malaysia and Iran are closely working together to further enhance the level of their relations. The leaders of both countries have quiet regularly exchanged visits and have also actively ventured into promising business opportunities. Iran ranked as the Malaysia＇s third West Asian trading partners along with the United Arab Emirates （UAE） and Saudi Arabia, provides a lot of opportunities for Malaysia to seize onto. In other words, Malaysia＇s contemporary relations with Iran will evolve beyond the dogma of the Iranian Revolution in 1979.

Consideration on the Organization of Peasant Market Entry

In the process of agricultural commercialization, it is crucial to develop specialized co-operative organizations as well as to apply initiatives to protect agriculture by the government. Government should organize peasants to enter, adapt and influence the market Peasants should participate and affect policies, monitor the implementation of agricultural protection policy, and form self-protecting mechanism through co-operative organizations.

Self Organizing Communities: Enhancing Cooperation through Competition

One of the open issues in today’s networking world is efficient content retrieval, storage, and provision. Numerous studies have been carried out in order to optimize the distribution and provision of content to end users. This is emphasized in today’s mobile networks that the ubiquity of network resources is considered an expected fact. In this paper we propose an architecture that is based on node co-operation that enhances the content distribution and retrieval. The architecture consists of the formation of loosely coupled and autonomous communities among nodes that share common interests where the already existing content is shared in a “common pool”. The co-operation is enforced by the acquisition of extra bandwidth that is distributed to the most helpful members. The autonomic aspect of the communities is based on the embedded mechanisms for cluster behavior, namely, voting, where the nodes decide themselves which members should be awarded, and reporting, where misbehaving nodes are removed from the community. In this paper the different elements of the architecture will be described, together with a theoretic study of its viability, and finally a set of simulations that evaluate its performance.

Prime Energy Challenges for Operating Power Plants in the GCC

There is a false notion of existing available, abundant, and long lasting fuel energy in the Gulf Cooperation Council (GCC) Countries;with continual income return from its exports. This is not true as the sustainability of this income is questionable. Energy problems started to appear, and can be intensified in coming years due to continuous growth of energy demands and consumptions. The demands already consume all produced Natural Gas (NG) in all GCC, except Qatar;and the NG is the needed fuel for Electric Power (EP) production. These countries have to import NG to run their EP plants. Fuel oil production can be locally consumed within two to three decades if the current rate of consumed energy prevails. The returns from selling the oil and natural gas are the main income to most of the GCC. While NG and oil can be used in EP plants, NG is cheaper, cleaner, and has less negative effects on the environment than fuel oil. Moreover, oil has much better usage than being burned in steam generators of steam power plants or combustion chambers of gas turbines. Introducing renewable energy or nuclear energy may be a necessity for the GCC to keep the flow of their main income from exporting oil. This paper reviews the GCC productions and consumptions of the prime energy (fuel oil and NG) and their role in electric power production. The paper shows that, NG should be the only fossil fuel used to run the power plants in the GCC. It also shows that the all GCC except Qatar, have to import NG. They should diversify the prime energy used in power plants;and consider alternative energy such as nuclear and renewable energy, (solar and wind) energy.

An Overall Urban System: Integrating Central Place Theory and Urban Network Idea in the Greater Pearl River Delta of China

Following a half century of popularity, central place theory experienced 20 years of neglect when the new urban system theory of network modeling gained attention at the beginning of the 1990s. However, central place theory remains valid, and it seems there has been a reemergence with it. Using the Greater Pearl River Delta (Greater PRD) as an experimental study region, this paper intends to present an empirical study that validates central place theory and shows that it can be integrated into an overall regional urban system. The study uses the compound Central Place Importance (CPI) to evaluate whether there is a hierarchy among the urban centers within the study area. The results indicate the existence of a hierarchy. Furthermore, empirical observation finds distinct complementarity relationships, rank-size distributions, and co-operative actions between the different cities, thus substantiating the claim that central place theory can be incorporated into an overall regional urban system. Besides, the presence of the densely distributed modern infrastructure system also appears to constitute a dimension of the overall urban system. There need further theoretical and empirical studies in order to support this proposition.

Teacher-Pupil Relationship in Implementing Modem Teaching Technologies

In the article, the features of using modern teaching tecnologies are investigated and results are revealed. The establishment of teacher-pupil relationships based on comfortable mutual trust and equal rights is the direct effect of proper and expedient use of innovative training technologies. Teaching technologies＇ features are explored, experiment examples are listed, and all these results are analysed in this article. In the article, modem teaching technologies＇ characteristic features are explored and the need of these features in teaching process with the teacher-pupil relationship is substantiated. Some conclusions were made to analyse all these points.