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Effects of comprehensive nursing with cognitive behavioral therapy in orthodontic osteodilated arch treatment
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作者 Xin Yang Zeng-Xiang Wang +3 位作者 Yu-Xing Tian Chao Peng Hui-Ning Yang Ying Wu 《World Journal of Clinical Cases》 SCIE 2024年第22期5051-5058,共8页
BACKGROUND This work explored the effects of cognitive behavior therapy(CBT)-based comprehensive nursing intervention(CNI)mode in arch expansion to treat patients with orthodontic osteodilated arch(OOA).AIM To explore... BACKGROUND This work explored the effects of cognitive behavior therapy(CBT)-based comprehensive nursing intervention(CNI)mode in arch expansion to treat patients with orthodontic osteodilated arch(OOA).AIM To explore the application effect of CBT-based CNI model in orthodontic expansion arch treatment.METHODS Using convenient sampling method,81 patients with OOA were selected and rolled into a control group(Ctrl group,40 cases)and an observation group(Obs group,41 cases).During the treatment,patients in the Ctrl group received routine nursing intervention mode,and the those in the Obs group received CBT mode on the basis of this.Before and after intervention,the incidence of oral mucositis,the mastery rate of correct arch expansion method,self-rating anxiety scale score,soft scale index,and plaque index were compared for patients in different groups.In addition,satisfaction and complications were comparatively analyzed.RESULTS Incidence of oral mucositis in the Obs group was lower(14.6%vs 38.5%),and the mastery rate of correct arch expansion method was obviously higher(90.2%vs 55.0%)was obviously higher(all P<0.05).Meanwhile,the soft scale index and plaque index in the Obs group were much lower(P<0.05).The compliance(90.24%)and satisfaction(95.12%)in the Obs group were greatly higher(P<0.05).CONCLUSION The CBT-based CNI mode greatly improved the mastery rate of correct arch expansion method during arch expansion in treating patients with OOA and enhanced the therapeutic effect of arch expansion and the oral health of patients,improving the patient compliance. 展开更多
关键词 Orthodontic osteodilated arch cognitive behavior therapy Comprehensive nursing intervention mode Nursing effect Pain management Oral care
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Measuring Cognitive and Psychosocial Accessibility to Modern Contraception: A Comprehensive Framework
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作者 Lonkila Moussa Zan Clémentine Rossier Caroline Moreau 《Health》 2024年第7期578-591,共14页
Nowadays, more than ever, the improvement of access to family planning (FP) has become an international goal. What constitutes access to FP? Current human rights-based contraceptive guidelines indicate that access beg... Nowadays, more than ever, the improvement of access to family planning (FP) has become an international goal. What constitutes access to FP? Current human rights-based contraceptive guidelines indicate that access begins as soon as women or couples express a desire to avoid pregnancy and their risk of unintended pregnancy is established. However, few studies have sought to define and measure cognitive and psychosocial access to contraception. To propose a comprehensive framework for the cognitive and psychosocial accessibility of contraception, we critically analyzed the literature on attitudes toward FP. The main dimensions that emerged were knowledge about FP, fear of side effects, approval of contraception, and contraceptive agency. We then identified and adjusted some questions that can capture these dimensions more comprehensively. As a result, we developed a questionnaire module comprising 15 questions, which was integrated into the 6th round of the PMA2020 survey in Burkina Faso in 2019. This research highlighted that previous studies have collected separate dimensions of contraceptive access, and the psychosocial dimension tended to be neglected. Our results demonstrate that it is possible to collect comprehensive data on cognitive and psychosocial dimensions of access to family planning. 展开更多
关键词 cognitive Dimensions Psychosocial Dimensions CONTRACEPTION Intention To Use Side effects
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Impact of propofol and sevoflurane anesthesia on cognition and emotion in gastric cancer patients undergoing radical resection 被引量:2
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作者 Ao-Han Li Su Bu +2 位作者 Ling Wang Ai-Min Liang Hui-Yu Luo 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第1期79-89,共11页
BACKGROUND Propofol and sevoflurane are commonly used anesthetic agents for maintenance anesthesia during radical resection of gastric cancer.However,there is a debate concerning their differential effects on cognitiv... BACKGROUND Propofol and sevoflurane are commonly used anesthetic agents for maintenance anesthesia during radical resection of gastric cancer.However,there is a debate concerning their differential effects on cognitive function,anxiety,and depression in patients undergoing this procedure.AIM To compare the effects of propofol and sevoflurane anesthesia on postoperative cognitive function,anxiety,depression,and organ function in patients undergoing radical resection of gastric cancer.METHODS A total of 80 patients were involved in this research.The subjects were divided into two groups:Propofol group and sevoflurane group.The evaluation scale for cognitive function was the Loewenstein occupational therapy cognitive assessment(LOTCA),and anxiety and depression were assessed with the aid of the self-rating anxiety scale(SAS)and self-rating depression scale(SDS).Hemodynamic indicators,oxidative stress levels,and pulmonary function were also measured.RESULTS The LOTCA score at 1 d after surgery was significantly lower in the propofol group than in the sevoflurane group.Additionally,the SAS and SDS scores of the sevoflurane group were significantly lower than those of the propofol group.The sevoflurane group showed greater stability in heart rate as well as the mean arterial pressure compared to the propofol group.Moreover,the sevoflurane group displayed better pulmonary function and less lung injury than the propofol group.CONCLUSION Both propofol and sevoflurane could be utilized as maintenance anesthesia during radical resection of gastric cancer.Propofol anesthesia has a minimal effect on patients'pulmonary function,consequently enhancing their postoperative recovery.Sevoflurane anesthesia causes less impairment on patients'cognitive function and mitigates negative emotions,leading to an improved postoperative mental state.Therefore,the selection of anesthetic agents should be based on the individual patient's specific circumstances. 展开更多
关键词 PROPOFOL SEVOFLURANE Radical resection of gastric cancer Anesthetic effect cognitive function Negative emotion
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Effective Capacity in Cognitive Radio Networks with Relay and Primary User Emulator 被引量:2
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作者 Luyong Zhang Yijie Yang +2 位作者 Xuan Li Jinhua Chen Yunbing Chi 《China Communications》 SCIE CSCD 2019年第11期130-145,共16页
In this paper,the transmission performances are studied in cognitive radio networks with primary user emulator and relay existence.In the proposed network,the users include primary users,secondary users and primary us... In this paper,the transmission performances are studied in cognitive radio networks with primary user emulator and relay existence.In the proposed network,the users include primary users,secondary users and primary user emulators.The decreasing access priority of the users are primary users,primary user emulators and secondary users.Different user access to the network results in different transmission effects.We impose interference power constraints on the secondary users to protect the primary users from being interfered.We also adopt the transmission mechanism that transits among more than one secondary transmitters,secondary receivers and relays.The transition models of the transmission states are proposed to describe the transmission mechanism.To investigate the transmission performances,the theory of effective capacity is adopted.The transmission performances in terms of effective capacity are expressed and demonstrated under different transmission policies.The overall effective capacity,as the overall data traffic in the cognitive radio network,is calculated.Besides,the overall effective capacity is demonstrated under different transmission strategies.The results show the greedy transmission strategy outperforms the rest of the transmission 8 policies in the overall effective capacity.For a larger number of the users,the effective capacity converges to a certain value. 展开更多
关键词 cognitive RADIO primary USER emulator(PUE) RELAY communication effective capacity transmission strategy
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Cognitive and Psychosocial Accessibility to Modern Contraception: Subscales Validation
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作者 Lonkila Moussa Zan Clémentine Rossier 《Health》 2023年第7期746-757,共12页
While studies have examined physical access to services, cognitive and psychosocial barriers to contraceptive use have received less attention, despite their impact on access. Research shows that fours main dimensions... While studies have examined physical access to services, cognitive and psychosocial barriers to contraceptive use have received less attention, despite their impact on access. Research shows that fours main dimensions exist under the broad concept of cognitive and psychosocial access. This study aims to validate the construction of these dimensions and measure the relation between them and their links with modern contraceptive use. We utilized a questionnaire module to collect 15 questions measuring these dimensions through the 6<sup>th</sup> round of the Performance monitoring and accountability 2020 (PMA2020) survey in Burkina in 2019. We employed the scale validation technique to choose appropriate measures (observable indicators or items) for constructing each latent dimension (unobservable) in our study. The items consisted of questions that utilized a 5-point Likert scale or dichotomous responses to capture various psychosocial aspects. To assess the validity, reliability, convergence, and divergence of the latent dimensions and items, we utilized the validscale command in Stata. The validation process confirmed the reliability of all the dimensions. Contraceptive approval is more aligned with birth spacing rather than birth limiting, reflecting prevailing social perceptions. Women’s contraceptive agency was found to be more associated with their ability to discuss and negotiate with their partners rather than independent decision-making. Correlations between dimensions were generally weak, but the levels of knowledge, agency, and approval of contraception are positively correlated with contraceptive use and intention to use. Giving women more decision-making power and providing information to address side-effect concerns can enhance contraceptive approval. 展开更多
关键词 cognitive Dimensions Psychosocial Dimensions CONTRACEPTION Intention to Use Side effects
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Cognitive and Behavioral Effects of Participatory Sex Education on the Dual Prevention of STI/HIV/AIDS and Unwanted Pregnancies among Adolescents in Kinshasa High Schools, DR Congo
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作者 Gabriel Vodiena Nsakala Yves Coppieters Patrick Kalambayi Kayembe 《Open Journal of Preventive Medicine》 2014年第4期204-215,共12页
Context: With the view to reorient both STI/HIV/AIDS prevention and adolescents pregnancies, this research study aims at evaluating cognitive and behavioral acquisitions, as well as the process of interactive sex educ... Context: With the view to reorient both STI/HIV/AIDS prevention and adolescents pregnancies, this research study aims at evaluating cognitive and behavioral acquisitions, as well as the process of interactive sex education participatory approach among adolescents in Kinshasa high schools. Methods: Based on a “pre and post” virtually experimental design, two crosswise surveys were conducted in Kinshasa, for six months in 2011-2012 on 484 high school students (pre-survey) and on 441 high school students (post-survey), whose age range from 14 - 19 years including both sexes. Two participatory educational talks (PET) “A” and “B”, covered weekly in two different schools, were compared to a control group school. The PET “A” consisted of interactive interpersonal communication sessions given by an external expert as a substitute for the life education course in one school. The PET “B” carried out in another school, included more educational talk sessions, led by the external expert and supplemented by a close follow-up of teenagers divided into small groups of 10 participants. The subjects’ assessment was based on their knowledge, attitudes and practices relating to STI/HIV/AIDS dual prevention as well as to unwanted pregnancies. Results: The subjects involved in the PET “B” displayed a better/higher performance based on their knowledge, attitudes and practices related to STI/HIV/AIDS dual prevention and unwanted pregnancies. Broadly speaking, knowledge has been improved 6 times with the PET “B” (OR = 6, 10, IC 95%) (3.24 - 11.9), and 3 times with the PET “A” (OR = 3, 45, IC 95%) (1.79 - 6.81), compared to control school. Similarly, findings on subjects’ attitudes show an improvement rated 12 times with the PET”B” (OR = 11, 99, IC 95%) (5.67 - 27.38) and 5 times for the PET “A” (OR = 5.51, IC 95%) (2.54 - 12.87). As far as the subjects’ practices are concerned, an improvement of 6 more times of protected sexual intercourses with the PET “B” compared with the control school group (OR = 6, 52, IC 95%) (3.60 - 12.0). The process assessment records a spontaneous involvement of schools enhanced by the positive contribution of Life Education and Biology teachers;add a massive participation of adolescents who requested permanent PET program. Conclusion: The results of this study suggest that school sexual education programs can be improved to increase the quality of apprenticeship. The use of interactive methods and the consideration of the adolescents’ specific needs that take into account the gender approach may bring about beneficial advantages on both educational outcomes and reproductive health of adolescents. 展开更多
关键词 cognitive and Behavioral effects Sex Education STI/HIV/AIDS Unwanted PREGNANCIES Adolescents DRC
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Multi-Objective Bacterial Foraging Optimization Algorithm Based on Effective Area in Cognitive Emergency Communication Networks
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作者 Shibing Zhang Xue Ji +1 位作者 Lili Guo Zhihua Bao 《China Communications》 SCIE CSCD 2021年第12期252-269,共18页
Cognitive emergency communication net-works can meet the requirements of large capac-ity,high density and low delay in emergency com-munications.This paper analyzes the properties of emergency users in cognitive emerg... Cognitive emergency communication net-works can meet the requirements of large capac-ity,high density and low delay in emergency com-munications.This paper analyzes the properties of emergency users in cognitive emergency communi-cation networks,designs a multi-objective optimiza-tion and proposes a novel multi-objective bacterial foraging optimization algorithm based on effective area(MOBFO-EA)to maximize the transmission rate while maximizing the lifecycle of the network.In the algorithm,the effective area is proposed to prevent the algorithm from falling into a local optimum,and the diversity and uniformity of the Pareto-optimal solu-tions distributed in the effective area are used to eval-uate the optimization algorithm.Then,the dynamic preservation is used to enhance the competitiveness of excellent individuals and the uniformity and diversity of the Pareto-optimal solutions in the effective area.Finally,the adaptive step size,adaptive moving direc-tion and inertial weight are used to shorten the search time of bacteria and accelerate the optimization con-vergence.The simulation results show that the pro-posed MOBFO-EA algorithm improves the efficiency of the Pareto-optimal solutions by approximately 55%compared with the MOPSO algorithm and by approx-imately 60%compared with the MOBFO algorithm and has the fastest and smoothest convergence. 展开更多
关键词 wireless communications emergency communications cognitive radio networks multi-objective optimization algorithm effective areas self-adaption
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Left- and Right-Handers May Unintentionally Apply Different Cognitive Strategies in Response to Situational Demands: Study Using the Block-Wise Proportion Congruency Effect
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作者 Kazuhito Yoshizaki Yurina Watanabe 《Journal of Behavioral and Brain Science》 2022年第1期10-21,共12页
We investigated the effects of handedness on developing latent cognitive response strategies according to situation variables. We used the findings of the block-wise Proportion Congruency (PC) effect in which the prop... We investigated the effects of handedness on developing latent cognitive response strategies according to situation variables. We used the findings of the block-wise Proportion Congruency (PC) effect in which the proportion of congruent trials in a given block modulates the compatibility effect in its block. The block-wise PC effect cannot be intentionally controlled. A Simon task with three different types of Proportion Congruency (PC) in a given block was used to measure the block-wise PC effects. This task was administered to 24 left-handed and 24 right-handed participants. The reaction time and error rates, consistent with previous studies, demonstrated that the block-wise PC effect was observed in left- and right-handers. Crucially, the block-wise PC effect was more pronounced in left- than right-handers, suggesting that left- and right-handers unintentionally apply different cognitive strategies in response to conflict resolution experiences. 展开更多
关键词 cognitive Control HANDEDNESS Block-Wise Proportion Congruency (PC) effect
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Relevance Theory-based Cognitive Study on the Communication Effect of “China's Stories”
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作者 Yang Xiaohong Wu Lingwei 《Contemporary Social Sciences》 2017年第6期23-32,共10页
Telling the story of China and transmitting the voice of China has become a strategy to promote the national image and cultural soft power of China. Since its implementation in 2013, China has ushered in a significant... Telling the story of China and transmitting the voice of China has become a strategy to promote the national image and cultural soft power of China. Since its implementation in 2013, China has ushered in a significant change in communication ideas and approaches. This strategy also enriches the communication genres of "China's stories" and more importantly enhances its communication effect. In this context, it is necessary to understand and study the significance of this strategic practice, assess the value realization of "China's stories" during the communication process, and thereby establish a basis for future communication of more "China's stories." Based on the factors of relevance theory, this paper analyzes the ideas of and approaches to effective communication of "China's stories" and proposes corresponding strategies. 展开更多
关键词 relevance theory China’s stories communication effect cognitive study
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Interventional effect of cognitive behavioral therapy on cancer-related fatigue in breast cancer patients: A systematic review
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作者 Ying Zhang Jia-Lei Ren +1 位作者 Yu-Hong Chen Wan-Min Qiang 《TMR Integrative Nursing》 2019年第6期199-206,共8页
Objective:To evaluate the effect of cognitive behavioral therapy on cancer-related fatigue in breast cancer patients.Methods:Computer search for CNKI,VIP,Wanfang database,CBM,PubMed,Embase,CINAHL,The Cochrane library ... Objective:To evaluate the effect of cognitive behavioral therapy on cancer-related fatigue in breast cancer patients.Methods:Computer search for CNKI,VIP,Wanfang database,CBM,PubMed,Embase,CINAHL,The Cochrane library as of 2019 randomized controlled trials on October 20 for cognitive behavioral therapy intervention for breast cancer due to fatigue.Results:A total of 6 RCTs were included,472 patients.Cognitive Behavioral Therapy has a strong effect on cancer related fatigue compared with the usual care[SMD=-1.19,95%CI(-1.86,-0.53),P=0.0004].Results:Available evidence suggests that CBT can alleviate cancer-related fatigue in breast cancer patients,and the above studies still need to continue to conduct relevant studies for validation. 展开更多
关键词 cognitive behavioral therapy Breast cancer Cancer-related fatigue Treatment effect Systematic review
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Channel Estimation and Effective Capacity over Imperfect Rayleigh Channel Environment in Cognitive Radio Networks
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作者 Mohamed Elalem Lian Zhao 《通讯和计算机(中英文版)》 2013年第7期1007-1018,共12页
关键词 瑞利衰落信道 无线电网络 信道估计 有效容量 状态转移模型 环境 功率分配 传输性能
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Clinical Effect of Electroacupuncture Baihui and Neiguan Acupoint on Cognitive Function Recovery in Elderly Patients after General Anesthesia
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作者 Yuming Zhang Haiyan Huo +3 位作者 Zhu Zhu Qifan Huo Jing Zhao Jun Wang 《Journal of Clinical and Nursing Research》 2021年第3期99-102,共4页
Objective:To study and analyze the clinical effect of electroacupuncture at Baihui and Neiguan Points on cognitive function recovery of elderly patients after general anesthesia.Methods:The subjects were 80 elderly pa... Objective:To study and analyze the clinical effect of electroacupuncture at Baihui and Neiguan Points on cognitive function recovery of elderly patients after general anesthesia.Methods:The subjects were 80 elderly patients who received general anesthesia from January 2019 to February 2021.According to different anesthesia methods,they were divided into research group(electroacupuncture at Baihui and Neiguan combined with conventional drug anesthesia)and control group(simple drug anesthesia).The postoperative cognitive function recovery of the two groups was observed and compared.Results:Compared with the control group,the MMSE score and POCD incidence of research group were significantly better.There was significant difference between the two groups(P<0.05).Conclusion:Conclusion electroacupuncture at Baihui and Neiguan combined with conventional drug anesthesia can promote the recovery of cognitive function and prevent cognitive dysfunction in elderly patients under general anesthesia. 展开更多
关键词 E
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Serum cystatin C levels are negatively correlated with post-stroke cognitive dysfunction 被引量:15
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作者 Dao-Xia Guo Zheng-Bao Zhu +12 位作者 Chong-Ke Zhong Xiao-Qing Bu Li-Hua Chen Tan Xu Li-Bing Guo Jin-Tao Zhang Dong Li Jian-Hui Zhang Zhong Ju Chung-Shiuan Chen Jing Chen Yong-Hong Zhang Jiang He 《Neural Regeneration Research》 SCIE CAS CSCD 2020年第5期922-928,共7页
Stroke is the leading cause of death and long-term disability worldwide,and cognitive impairment and dementia are major complications of ischemic stroke.Cystatin C (CysC) has been found to be a neuroprotective factor ... Stroke is the leading cause of death and long-term disability worldwide,and cognitive impairment and dementia are major complications of ischemic stroke.Cystatin C (CysC) has been found to be a neuroprotective factor in animal studies.However,the relationship between CysC levels and cognitive dysfunction in previous studies has revealed different results.This prospective observational study investigated the correlation between serum CysC levels and post-stroke cognitive dysfunction at 3 months.Data from 638 patients were obtained from the China Antihypertensive Trial in Acute Ischemic Stroke (CATIS).Cognitive dysfunction was assessed using the Mini-Mental State Examination (MMSE) at 3 months after stroke.According to the MMSE score,308 patients (52.9%) had post-stroke cognitive dysfunction.After adjusting for potential confounding factors,the odds ratio (95% CI) of post-stroke cognitive dysfunction for the highest quartile of serum CysC levels was 0.54 (0.30–0.98),compared with the lowest quartile.The correlation between serum CysC and cognitive dysfunction was modified by renal function status.We observed a negative linear dose-response correlation between CysC and cognitive dysfunction in patients with normal renal function (Plinearity = 0.044),but not in those with abnormal renal function.Elevated serum CysC levels were correlated with a low risk of 3-month cognitive dysfunction in patients with acute ischemic stroke,especially in those with normal renal function.The current results suggest that CysC is a protective factor for post-stroke cognitive dysfunction,and could be used to treat post-stroke cognitive dysfunction.The CATIS study was approved by the Institutional Review Boards at Soochow University from China (approval No.2012-02) on December 30,2012,and was registered at ClinicalTrials.gov (identifier No.NCT01840072) on April 25,2013. 展开更多
关键词 abnormal RENAL FUNCTION cognitive dysfunction CYSTATIN C ISCHEMIC stroke Mini-Mental State Examination neural regeneration NEUROPROTECTIVE effect normal RENAL FUNCTION
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Practice and Effect of Appropriate Error-correction in English Teaching 被引量:2
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作者 任静明 胡蓉 《Journal of Donghua University(English Edition)》 EI CAS 2002年第2期140-142,共3页
This paper points out that with interference from their native language and culture, Chinese students will inevitably make some errors in the process of learning English. It is important for teachers to know when and ... This paper points out that with interference from their native language and culture, Chinese students will inevitably make some errors in the process of learning English. It is important for teachers to know when and how to correct the students’ errors. By employing error-correction skillfully and appropriately, one can expect to improve the present English teaching and learning, to develop the self-confidence and self-esteem in students themselves. 展开更多
关键词 error-correction practice effect
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Framework of Pattern Recognition Model Based on the Cognitive Psychology 被引量:1
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作者 WANG Shugen 《Geo-Spatial Information Science》 2002年第2期74-78,共5页
According to the fundamental theory of visual cognition mechanism and cognitive psychology,the visual pattern recognition model is introduced briefly.Three pattern recognition models,i.e.template_based matching model,... According to the fundamental theory of visual cognition mechanism and cognitive psychology,the visual pattern recognition model is introduced briefly.Three pattern recognition models,i.e.template_based matching model,prototype_based matching model and feature_based matching model are built and discussed separately.In addition,the influence of object background information and visual focus point to the result of pattern recognition is also discussed with the example of recognition for fuzzy letters and figures 展开更多
关键词 PERCEPTION perception processing cognitive psychology pattern recognition superiority effect
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First Time Demonstration of the Quantum Interference Effect during Integration of Cognition and Emotion in Children 被引量:1
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作者 Elio Conte Rui Freire Lucas 《World Journal of Neuroscience》 2015年第2期91-98,共8页
Quantum cognition is a scientific approach to cognitive phenomena which makes use of the mathematical formalism of quantum theory. Quantum interference effect constitutes one of this theory’s main tenets and has been... Quantum cognition is a scientific approach to cognitive phenomena which makes use of the mathematical formalism of quantum theory. Quantum interference effect constitutes one of this theory’s main tenets and has been repeatedly demonstrated experimentally, in the last decade, in adult subjects. In the present paper, we aim to demonstrate, for the first time, the existence of thequantum interference effect on children during an experiment involving an integration of cognition and emotion. Our positive results consolidate the presuppositions of quantum cognition, enlarging its field of application to children’s mental apparatus and evidence the important question to consider the quantum model in the current investigated question of the interaction of cognition and emotion in children at neurological and psychological levels. 展开更多
关键词 QUANTUM cognitION QUANTUM Interference effect QUANTUM MECHANICS Emotion-cognition Interaction in CHILDREN
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Antidepressant and cognitive activities of intranasal piperine-encapsulated liposomes 被引量:1
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作者 Aroonsri Priprem Pennapa Chonpathompikunlert +1 位作者 Saengrawee Sutthiparinyanont Jintanaporn Wattanathorn 《Advances in Bioscience and Biotechnology》 2011年第2期108-116,共9页
Antidepressant and cognitive effects of piperine -encapsulated liposomes (PL) were investigated in male Wistar rats. Oral piperine (5 mg/kg body weight/day) and intranasal PL (7.2 μg/day) were randomly assigned to da... Antidepressant and cognitive effects of piperine -encapsulated liposomes (PL) were investigated in male Wistar rats. Oral piperine (5 mg/kg body weight/day) and intranasal PL (7.2 μg/day) were randomly assigned to daily administer for 14 days to rats which were subjected to forced swimming, Mor-ris water maze and spontaneous motor behavior tests. PL significantly exhibited anti-depression like activity and cognitive enhancing effects, in comparison to the control groups after the first dose (p < 0.01) and the effects could be maintained throughout the period of study. Quantitative analysis of the brain homogenates by HPLC indicated that piperine, delivered either orally or nasally, distributed to the hippocampus at a higher extent than the cortex and that the time to peak concentration of nasal PL was shorter than for the oral piperine. Intranasal PL was, thus, potential in delivery of piperine, at a low dose, to exert its an-tidepressant and cognitive enhancing activities. 展开更多
关键词 PIPERINE Liposome Anti-Depression Activity cognitive Enhancement effect INTRANASAL Route
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Anodal transcranial direct current stimulation alleviates cognitive impairment in an APP/PS1 model of Alzheimer’s disease in the preclinical stage 被引量:1
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作者 Yin-Pei Luo Zhi Liu +4 位作者 Cong Wang Xiu-Fang Yang Xiao-Ying Wu Xue-Long Tian Hui-Zhong Wen 《Neural Regeneration Research》 SCIE CAS CSCD 2022年第10期2278-2285,共8页
Anodal transcranial direct current stimulation(AtDCS)has been shown to alleviate cognitive impairment in an APP/PS1 model of Alzheimer’s disease in the preclinical stage.However,this enhancement was only observed imm... Anodal transcranial direct current stimulation(AtDCS)has been shown to alleviate cognitive impairment in an APP/PS1 model of Alzheimer’s disease in the preclinical stage.However,this enhancement was only observed immediately after AtDCS,and the long-term effect of AtDCS remains unknown.In this study,we treated 26-week-old mouse models of Alzheimer’s disease in the preclinical stage with 10 AtDCS sessions or sham stimulation.The Morris water maze,novel object recognition task,and novel object location test were implemented to evaluate spatial learning memory and recognition memory of mice.Western blotting was used to detect the relevant protein content.Morphological changes were observed using immunohistochemistry and immunofluorescence staining.Six weeks after treatment,the mice subjected to AtDCS sessions had a shorter escape latency,a shorter path length,more platform area crossings,and spent more time in the target quadrant than sham-stimulated mice.The mice subjected to AtDCS sessions also performed better in the novel object recognition and novel object location tests than sham-stimulated mice.Furthermore,AtDCS reduced the levels of amyloid-β42 and glial fibrillary acidic protein,a marker of astrocyte activation,and increased the level of neuronal marker NeuN in hippocampal tissue.These findings suggest that AtDCS can improve the spatial learning and memory abilities and pathological state of an APP/PS1 mouse model of Alzheimer’s disease in the preclinical stage,with improvements that last for at least 6 weeks. 展开更多
关键词 Alzheimer’s disease amyloid-β anodal transcranial direct current stimulation cognitive function INFLAMMATION long-term effect NEURON preclinical stage
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Action Research: The Application of Cognitive Load Theory to Reading Teaching 被引量:1
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作者 GAO Jun-xia 《Sino-US English Teaching》 2007年第4期19-23,共5页
In this report, the author found out that the materials on hand imposed undue cognitive load on students. In order to maximize learning, the author changed her instructional design, kept a close eye on the whole proce... In this report, the author found out that the materials on hand imposed undue cognitive load on students. In order to maximize learning, the author changed her instructional design, kept a close eye on the whole process, and ultimately discovered that reducing the cognitive load of the learning materials is beneficial for the increase of learners' interest and the liven-up of the classroom atmosphere, which can finally maximize learners' language learning. 展开更多
关键词 cognitive load split-attention effect redundancy effect reading teaching
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高校教师学术创业经历对创新创业教学效果的影响研究 被引量:1
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作者 李华晶 刘佳琪 +2 位作者 薛红志 吴亚军 陈睿绮 《扬州大学学报(高教研究版)》 2024年第2期46-57,共12页
从学术创业理论视角出发,通过对全国多所高校949名创新创业教师进行问卷调查,再运用结构方程模型构建并验证教师学术创业经历对创新创业教学效果的影响机理,结果表明:高校创新创业教师学术创业经历对创新创业教学效果有显著的直接正向影... 从学术创业理论视角出发,通过对全国多所高校949名创新创业教师进行问卷调查,再运用结构方程模型构建并验证教师学术创业经历对创新创业教学效果的影响机理,结果表明:高校创新创业教师学术创业经历对创新创业教学效果有显著的直接正向影响,学术创业经历通过提升教学认知与能力进而积极促进教师创新创业教学效果。因此,应进一步重视和加强学术创业实践、提升教学知行水平,从而促进创新创业教学效果的提升。 展开更多
关键词 学术创业 创新创业 教学效果 高校教师 认知与能力
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