An Eye-Movement Study on the Cognitive Neuroscience Mechanisms of Chinese Classifier Construction

The study manipulated semantic and syntactic variables to explore the cognitive neuroscience mechanisms of Chinese classifier construction"yi+N(CL)+N".It was indicated:First,the mismatch could be dissolved if and only if the CL and modified noun were semantically related,which implied the significance of semantics in dissolving syntactic conflicts and processing linguistic items.Second,syntactic and semantic information were both activated at the early and late stages of language processing,which is consistent with the claims of the extended Concurrent Model.Third,the Access Mechanism of CLs,i.e.items in ordinary partitive phrases and temporary partitive phrases was identified.The former were addressed in a direct way,while the latter were processed in an assembled way.

Cognitive training for elderly patients with early Alzheimer’s disease in the Qinghai-Tibet Plateau: A pilot study

BACKGROUND Alzheimer’s disease(AD)influences the social and economic quality of life of older adult patients and their families.AIM To explore the efficacy of cognitive training in clinical nursing for patients with early AD residing in the plateau area.METHODS This pilot study was conducted in patients with early AD treated in the Geriatric Department of the Qinghai Provincial People’s Hospital between August 2019 and March 2021.The patients were divided into a cognitive training group and a conventional nursing group using the random number table method.Patients in the conventional nursing group received conventional nursing,whereas the patients in the cognitive training group received the new nursing intervention.The mini-mental state examination(MMSE)and activities of daily living(ADL)scales were used to compare the cognitive ability and daily activities,respectively,between the two groups before and after the intervention.RESULTS Sixty patients were enrolled in this study,with 30 patients in the cognitive training group and conventional nursing group,respectively.The MMSE and ADL scores were significantly higher in the cognitive training group than in the conventional nursing group after the intervention(MMSE:25.11±2.02 vs 22.26±1.23,P=0.032;ADL:68.72±4.86 vs 60.16±2.27,P=0.018).CONCLUSION The application of cognitive training in clinical nursing for patients with early AD could improve both their cognitive ability and ADL.This method could be applied in clinical practice to manage cognitive dysfunction in patients with early AD.

Connecting the P300 to the diagnosis and prognosis of unconscious patients

The residual consciousness of unconscious patients can be detected by studying the P300, a wave among event-related potentials. Previous studies have applied tones, the subject＇s name and other names as stimuli. However, the results were not satisfactory. In this study, we changed the constituent order of subjects＇ two-character names to create derived names. The subject＇s derived names, together with tones and their own names, were used as auditory stimuli in event-related potential experiments. Healthy controls and unconscious patients were included in this study and made to listen to these auditory stimuli. In the two paradigms, a sine tone followed by the subject＇s own name and the subject＇s derived name followed by the subject＇s own name were used as standard and deviant stimuli, respectively. The results showed that all healthy controls had the P300 using both paradigms, and that the P300 in the second paradigm had a longer latency and two peaks. All minimally conscious state patients had the P300 in the first paradigm and the majority of them had the P300 in the second paradigm. Most vegetative state patients had no P300. Patients who showed the P300 in the two paradigms had more residual consciousness, and patients with the two-peak P300 had a higher probability of awakening within a short time. Our experimental findings suggest that the P300 event-related potential could reflect the conscious state of unconscious patients.

Procedural learning changes in patients with Wilson's disease

In the present study, we compared explicit memory performance, using the Wechsler Memory Scale and implicit memory performance, using the Nissen software version of the serial reaction time task, in patients with Wilson＇s disease to normal controls. The Wilson＇s disease patients exhibited deficits in explicit memory tasks, such as figure recall and understanding memory. Moreover, the Wilson＇s disease patients exhibited deficits in implicit memory tasks, including significantly prolonged response times. These findings indicate that Wilson＇s disease patients have explicit and implicit partial memory impairments.

A novel mind-set in primate experimentation:Implications for primate welfare

We emphasize the importance of studying the primate brain in cognitive neuroscience and suggest a new mind-set in primate experimentation within the boundaries of animal welfare regulations.Specifically,we list the advantages of investigating both genes and neural mechanisms and processes in the emergence of behavioral and cognitive functions,and propose the establishment of an open field of primate research.The latter may be conducted by implementing and harmonizing experimental practices with ethical guidelines that regulate(1)management of natural parks with free-moving populations of target nonhuman primates,(2)establishment of indoor-outdoor labs for both system genetics and neuroscience investigations,and(3)hotel space and technologies which remotely collect and dislocate information regarding primates geographically located elsewhere.

Components and sequential changes in event-related potential induced by gaze orientation processing under a reflective attention cue paradigm

Gaze orientation induces activation of relevant brain regions, presents differences in specificity and time course, and is exhibited in patients with brain injury. However, the components of activated event-related potential remain controversial. Previous studies of behavior and cognitive neuroscience related to gaze orientation investigated conscious attention of visual orientation. The present study explored gaze orientation processing-induced event-related potential components and changes with time using reflective orientation of visual attention under a reflective attention cue paradigm. Visual attention processing of gaze orientation was recorded using event-related potential and electroencephalographic recording. Results demonstrated that the reflective attention cue task evoked early directing attention negativity and anterior directing attention negativity, but did not trigger late directing attention positivity. These results suggest that reflective attention occurs over a short time of visual stimulus presentation. During the early stage of attention processing, early directing attention negativity and anterior directing attention negativity were detected, but late directing attention positivity did not occur. These results confirmed reflectivity and time-course superiority of gaze orientation attention processing.

Ground-0 Axioms vs.First Principles and Second Law:From the Geometry of Light and Logic of Photon to Mind-Light-Matter Unity-AI&QI

Without the geometry of light and logic of photon,observer-observability forms a paradox in modern science,truthequilibrium finds no unification,and mind-light-matter unity is unreachable in spacetime.Subsequently,quantum mechanics has been shrouded with mysteries preventing itself from reaching definable causality for a general purpose analytical quantum computing paradigm.Ground-0 Axioms are introduced as an equilibrium-based,dynamic,bipolar set-theoretic unification of the first principles of science and the second law of thermodynamics.Related literatures are critically reviewed to justify the self-evident nature of Ground-0 Axioms.A historical misinterpretation by the founding fathers of quantum mechanics is identified and corrected.That disproves spacetime geometries(including but not limited to Euclidean and Hilbert spaces)as the geometries of light and truth-based logics(including but not limited to bra-ket quantum logic)as the logics of photon.Backed with logically definable causality and Dirac 3-polarizer experiment,bipolar quantum geometry(BQG)and bipolar dynamic logic(BDL)are identified as the geometry of light and the logic of photon,respectively,and wave-particle complementarity is shown less fundamental than bipolar complementarity.As a result,Ground-0 Axioms lead to a geometrical and logical illumination of the quantum and classical worlds as well as the physical and mental worlds.With logical resolutions to the EPR and Schr?dinger’s cat paradoxes,an analytical quantum computing paradigm named quantum intelligence(QI)is introduced.It is shown that QI makes mind-light-matter unity and quantum-digital compatibility logically reachable for quantumneuro-fuzzy AI-machinery with groundbreaking applications.It is contended that Ground-0 Axioms open a new era of science and philosophy—the era of mind-light-matter unity in which humanlevel white-box AI&QI is logically prompted to join Einstein’s grand unification to foster major scientific advances.