Twelve known compounds, colchicine, 2-demethylcolchicine, 2-demethyldemecolcine, 2-demethylcolchifoline, 2-demethyl-lumicolchicine, lumicolchicine, demecolcine, luteolin, apigenin, n-hentriacontane, n-triacontanol and...Twelve known compounds, colchicine, 2-demethylcolchicine, 2-demethyldemecolcine, 2-demethylcolchifoline, 2-demethyl-lumicolchicine, lumicolchicine, demecolcine, luteolin, apigenin, n-hentriacontane, n-triacontanol and sitosterol were isolated from cormsand flowers of colchicum autumnale Liliaceae which was introduced from Europe and cultivated in Zhaotong Yunnan, China The contents ofcolchicine in corms and flowers of colchicum autumnale were 0.015% and 0.04% respectively, and the content of demecolcine in corms was0.043%.展开更多
The secondary metabolites synthesized by plants are economically important chemical compounds in the agricultural and industrial areas such as food, perfumery and pharmaceutical sectors. In recent years, attempts for ...The secondary metabolites synthesized by plants are economically important chemical compounds in the agricultural and industrial areas such as food, perfumery and pharmaceutical sectors. In recent years, attempts for their production by in vitro plant cell and tissue cultures have been accelerated considerably. Colchicine, the principle secondary metabolite of Colchicum autumnale L. and Gloriosa superba L., is an important alkaloid that has poison effect used for treatment of various diseases and plant breeding studies. Presently, colchicine has been produced by using the seeds of C. autumnale L. and the tubers of G. superba L. through different chemical extraction methods. Applying in vitro plant cell and tissue cultures together with metabolic and genetic engineering techniques, large-scale production of colchicine can be achieved from the above two plant species.展开更多
文摘Twelve known compounds, colchicine, 2-demethylcolchicine, 2-demethyldemecolcine, 2-demethylcolchifoline, 2-demethyl-lumicolchicine, lumicolchicine, demecolcine, luteolin, apigenin, n-hentriacontane, n-triacontanol and sitosterol were isolated from cormsand flowers of colchicum autumnale Liliaceae which was introduced from Europe and cultivated in Zhaotong Yunnan, China The contents ofcolchicine in corms and flowers of colchicum autumnale were 0.015% and 0.04% respectively, and the content of demecolcine in corms was0.043%.
文摘The secondary metabolites synthesized by plants are economically important chemical compounds in the agricultural and industrial areas such as food, perfumery and pharmaceutical sectors. In recent years, attempts for their production by in vitro plant cell and tissue cultures have been accelerated considerably. Colchicine, the principle secondary metabolite of Colchicum autumnale L. and Gloriosa superba L., is an important alkaloid that has poison effect used for treatment of various diseases and plant breeding studies. Presently, colchicine has been produced by using the seeds of C. autumnale L. and the tubers of G. superba L. through different chemical extraction methods. Applying in vitro plant cell and tissue cultures together with metabolic and genetic engineering techniques, large-scale production of colchicine can be achieved from the above two plant species.
