A is a tumor associated antigen. Monoclonal antibody (mAb) against 17 1A has been used in adjuvant therapy of colorectal carcinoma. Using mAb against 17 1A antigen on affinity chromatography, a novel putative tumor ...A is a tumor associated antigen. Monoclonal antibody (mAb) against 17 1A has been used in adjuvant therapy of colorectal carcinoma. Using mAb against 17 1A antigen on affinity chromatography, a novel putative tumor associated antigen (P50) whose relative molecular mass is 5 0×10 4 has been isolated from human colorectal tumor tissues which are recognized by mAbs 17 1A and M79, while the relative molecular mass of 17\|1A antigen isolated from several colorectal tumor cell lines is 3 3×10 4. P50 was recognized by mAbs 17 1A and M79 which are specific mAbs against 17 1A antigen.展开更多
基金the Ministry of Education of China !(No .1 996 4 6 6 )
文摘A is a tumor associated antigen. Monoclonal antibody (mAb) against 17 1A has been used in adjuvant therapy of colorectal carcinoma. Using mAb against 17 1A antigen on affinity chromatography, a novel putative tumor associated antigen (P50) whose relative molecular mass is 5 0×10 4 has been isolated from human colorectal tumor tissues which are recognized by mAbs 17 1A and M79, while the relative molecular mass of 17\|1A antigen isolated from several colorectal tumor cell lines is 3 3×10 4. P50 was recognized by mAbs 17 1A and M79 which are specific mAbs against 17 1A antigen.