Construction and Analysis of Three-dimensional Graphic Model of Single-chain Fv Derived from an Anti-human Placental Acidic Isoferritin Monoclonal Antibody by Computer

Summary: A three-dimensional (3D) graphic model of a single-chain Fv (scFv) which was derived from an anti-human placental acidic isoferritin (PAF) monoclonal antibody (MAb) was construct- ed by a homologous protein-predicting computer algorithm on Silicon graphic computer station. The structure, surface static electricity and hydrophobicity of scFv were investigated. Computer graphic modelling indicated that all regions of scFv including the linker, variable regions of the heavy (VH) and light (VL) chains were suitable. The VH region and the VL region were involved in composing the 'hydrophobic pocket'. The linker was drifted away VH and VL regions. The complementarity determining regions (CDRs) of VH and VL regions surrounded the 'hydrophobic pocket'. This study provides a theory basis for improving antibody affinity, investigating antibody structure and analyzing the functions of VH and VL regions in antibody activity.

细颗粒无烟煤焦在CFB锅炉燃烧室内的燃尽特性研究

建立细颗粒无烟煤焦在CFB燃烧室的燃烧模型。模型考虑颗粒与烟气的能量交换、炉内的流体动力特性、炉膛中氧气浓度分布、分离器的分离特性和颗粒在炉内停留时间等因素的影响,能较好描述细无烟煤焦的燃烧行为,反映出CFB锅炉飞灰碳在50μm粒径档附近处出现峰值分布的特征,与工业实际运行结果吻合良好。模型求解结果表明:提高燃烧温度对于福建无烟煤细颗粒的燃尽有利,但当温度高于1000℃时,进一步提高燃烧温度对降低飞灰含碳意义不大。另外,提高过量空气系数、降低炉膛烟气流速、提高锅炉分离器分离效率等有利于细无烟煤焦的燃尽。

DGS循环流化炉的技术开发

进行了ＤＧＳ循环流化炉的冷态试验和燃烧试验，考察了炉内物料在流化状态下，给料量、风量、温度及压力之间的关系，为下一步煤的流化气化工作打下基础。

燃煤循环流化床模型与试验研究

利用循环流化床内气 -固两相流动等基础方面的研究成果 ,根据本文床内气固浓 -淡流动模型 ,建立适用不同结构参数的循环流化床燃烧模型 ,考虑了床内气体、固体颗粒的返混、循环过程 ,以及煤燃烧、NO的生成和分解、颗粒磨损等因素。在循环流化床燃烧试验台上进行实验研究 ,模型仿真结果和实验数据吻合良好 ,表明气固两相浓

A Sufficient Condition for a Wire-Frame Representing a Solid Modeling Uniquely

Generally speaking, it is impossible for a wire-frame to define a 3D object uniquely. But wire-frame as a graphics medium is still applied in some industrial areas. A sufficient condition is presented in this paper. If this condition is satisfied by a wire-frame, then the wire-frame can represent a 3D object uniquely The result is applied to manufacturing of progressive stripe.

初始条件对喷雾火焰着火影响的大涡模拟研究

本文基于LES-LEM模拟方法开展了不同环境温度、压力条件下正庚烷喷雾火焰的大涡模拟研究。首先,通过与ECN喷雾燃烧基础数据库(Engine Combustion Network,ECN)中的实验结果进行对比,发现LE-LEM方法预测的着火延迟期和火焰浮升长度与实验值非常符合。因此,基于此分析了不同发动机工况下喷雾燃烧的着火和燃烧过程。结果显示高温火核首先出现在浓混合气区域,同时,喷雾火焰中同时存在预混和非预混燃烧。计算结果显示燃烧能够使喷雾火焰加速向下游发展,但高环境压力又能抑制喷雾火焰向下游运动。