A COMBINATORIAL APPROACH TO THE OXIDATION RESISTANCE OF (Ti,Al)N AND Ti-Al-Si-N HARD COATINGS

The increasing complexity of modern functional materials leads to the demandof a cost efficient tool for the development of new products. One possible approach to this questionis the adaptation of combinatorial methods to the specific requirements of materials industry.These methods, originally developed for the pharmaceutical industry, have recently been applied tothe screening of superconductive, magnetoresistant and photoluminescent materials. The principle ofthese combinatorial approaches is the deposition of large materials libraries in one processcombined with fast methods for the determination of the resulting properties. In this paper, thedeposition and characterization of laterally graded materials libraries (composition spread) ispresented. The films have been deposited by reactive magnetron sputtering, using two or threemetallic targets at a low angle to the substrate surface as well as a system of apertures. Toillustrate the advantages of combinatorial approaches for the development of advanced materials, themulticomponent metastable hardcoatings (Ti,Al)N and Ti-Al-Si-N are discussed with special emphasison the relations between structure and composition on the one hand and the oxidation resistance ofthese coatings on the other. The results illustrate that the composition spread approach is apowerful and cost efficient tool for the development and optimization of new multicomponentfunctional materials.

Functional Peptides from One-bead One-compound High-throughput Screening Technique

Combinatorial chemistry provides a cost-effective method for the rapid discovery of new functional peptides.One-bead one-compound(OBOC)high-throughput screening technique offers a lot of structurally diverse peptides to be rapidly synthesized and screened for binding to a target of interest.The OBOC peptide library screening involves three main steps:library construction,positive beads separation,and peptide sequencing.This review mainly summarizes some special technique tips during functional peptide screening and potential future directions of the OBOC high-throughput screening technique.

Recent progress on discovery of novel phosphors for solid state lighting

Luminescent materials play indispensable roles in many application areas such as lighting,advanced displays,bio-imaging,medical treatments,sensing and detection.Pursuing new luminescent materials with improved or desired properties is an endless mission,driven by increasing demands of advances in technologies and applications.The traditional trial-and-error method,usually based on intensive experiments,cannot search for new materials in a fast and efficient way,therefore alternative model-or theory-based approaches for materials discovery need to be developed.In this work we overviewed several promising methods for screening and discovering novel luminescent materials,including solid state combinatorial chemistry,chemical unit substitution,single particle diagnosis and high-throughput calculations.These methods,having their own merits and demerits,enable to search for new phosphor materials with interesting properties for white light-emitting diodes(wLEDs)rapidly and efficiently.Finally,data-driven discovery of materials is emphasized as a state-of-art approach.