Data envelopment analysis（DEA） is a mathematical programming approach to appraise the relative efficiencies of peer decision-making unit（DMU）,which is widely used in ranking DMUs.However,almost all DEA-related ran...Data envelopment analysis（DEA） is a mathematical programming approach to appraise the relative efficiencies of peer decision-making unit（DMU）,which is widely used in ranking DMUs.However,almost all DEA-related ranking approaches are based on the self-evaluation efficiencies.In other words,each DMU chooses the weights it prefers to most,so the resulted efficiencies are not suitable to be used as ranking criteria.Therefore this paper proposes a new approach to determine a bundle of common weights in DEA efficiency evaluation model by introducing a multi-objective integer programming.The paper also gives the solving process of this multi-objective integer programming,and the solution is proven a Pareto efficient solution.The solving process ensures that the obtained common weight bundle is acceptable by a great number of DMUs.Finally a numeral example is given to demonstrate the approach.展开更多
This paper stipulates that the subject-based library liaison service to a university's teaching and research programs with certain embedded distinctive features should become the mainstream modus operandi of its l...This paper stipulates that the subject-based library liaison service to a university's teaching and research programs with certain embedded distinctive features should become the mainstream modus operandi of its library service. It takes the innovative service program based on an IC2 conceptualized program at Shanghai Jiao Tong University Library(thereafter abbreviated as SJTUL) as a concrete example to elucidate the merit of such an endeavor. Specifically, this paper discusses the particular development background, overall objectives and service contents of the IC2 motivated program at SJTUL. By presenting a detailed account of some of the key measures, major achievements and also possible future directions of library service development under the guiding principles of SJTUL's IC2 program, these authors hope that its innovative library practice may serve as a reference for other academic librarians to gain some inspirations for their own parallel service innovations or refinement focused on subject-oriented library liaison service to their constituents and parent institution's curricula and research projects.展开更多
Previous studies have shown that baicalin prevented iron accumulation after substantia nigra injury, reduced divalent metal transporter 1 expression, and increased ferroportin 1 expression in the substantia nigra of r...Previous studies have shown that baicalin prevented iron accumulation after substantia nigra injury, reduced divalent metal transporter 1 expression, and increased ferroportin 1 expression in the substantia nigra of rotenone-induced Parkinson＇s disease rats. In the current study, we investigated the relationship between iron accumulation and transferrin expression in C6 cells, to explore the mechanisms of the inhibitory effect of baicalin on iron accumulation observed in Parkinson＇s disease rats. Iron content was detected using inductively coupled plasma-atomic emission spectroscopy. Results showed that iron content decreased 41% after blocking divalent metal transporter 1 and ferroportin 1 proteins. After treatment with ferric ammonium citrate of differing concentrations （10, 50, 100, 400 ktg/mL） in C6 glioma cells, cell survival rate and ferroportin 1 expression were negatively correlated with ferric ammonium citrate concentration, but divalent metal transporter 1 expression positively correlated with ferric ammonium citrate concentration. Baicalin or deferoxamine reduced divalent metal transporter 1 expression, but increased ferroportin 1 expression in the 100 μg/mL ferric ammonium citrate-loaded C6 cells. These results indicate that baicalin down-regulated iron concentration, which positively regulat- ed divalent metal transporter 1 expression and negatively regulated ferroportin 1 expression, and decreased iron accumulation in the substantia nigra.展开更多
基金supported by the National Natural Science Foundation of China for Innovative Research Groups(70821001)and the National Natural Science Foundation of China(70801056)
文摘Data envelopment analysis（DEA） is a mathematical programming approach to appraise the relative efficiencies of peer decision-making unit（DMU）,which is widely used in ranking DMUs.However,almost all DEA-related ranking approaches are based on the self-evaluation efficiencies.In other words,each DMU chooses the weights it prefers to most,so the resulted efficiencies are not suitable to be used as ranking criteria.Therefore this paper proposes a new approach to determine a bundle of common weights in DEA efficiency evaluation model by introducing a multi-objective integer programming.The paper also gives the solving process of this multi-objective integer programming,and the solution is proven a Pareto efficient solution.The solving process ensures that the obtained common weight bundle is acceptable by a great number of DMUs.Finally a numeral example is given to demonstrate the approach.
基金supported by the National Social Science Foundation of China(Grant No.08CTQ001)the Elsevier Foundation of Collaborative Digital Reference Service System(CDRSS)for university libraries in China
文摘This paper stipulates that the subject-based library liaison service to a university's teaching and research programs with certain embedded distinctive features should become the mainstream modus operandi of its library service. It takes the innovative service program based on an IC2 conceptualized program at Shanghai Jiao Tong University Library(thereafter abbreviated as SJTUL) as a concrete example to elucidate the merit of such an endeavor. Specifically, this paper discusses the particular development background, overall objectives and service contents of the IC2 motivated program at SJTUL. By presenting a detailed account of some of the key measures, major achievements and also possible future directions of library service development under the guiding principles of SJTUL's IC2 program, these authors hope that its innovative library practice may serve as a reference for other academic librarians to gain some inspirations for their own parallel service innovations or refinement focused on subject-oriented library liaison service to their constituents and parent institution's curricula and research projects.
基金supported by the Scientific Research Common Program of Beijing Municipal Commission of Education,No.KM20110025010
文摘Previous studies have shown that baicalin prevented iron accumulation after substantia nigra injury, reduced divalent metal transporter 1 expression, and increased ferroportin 1 expression in the substantia nigra of rotenone-induced Parkinson＇s disease rats. In the current study, we investigated the relationship between iron accumulation and transferrin expression in C6 cells, to explore the mechanisms of the inhibitory effect of baicalin on iron accumulation observed in Parkinson＇s disease rats. Iron content was detected using inductively coupled plasma-atomic emission spectroscopy. Results showed that iron content decreased 41% after blocking divalent metal transporter 1 and ferroportin 1 proteins. After treatment with ferric ammonium citrate of differing concentrations （10, 50, 100, 400 ktg/mL） in C6 glioma cells, cell survival rate and ferroportin 1 expression were negatively correlated with ferric ammonium citrate concentration, but divalent metal transporter 1 expression positively correlated with ferric ammonium citrate concentration. Baicalin or deferoxamine reduced divalent metal transporter 1 expression, but increased ferroportin 1 expression in the 100 μg/mL ferric ammonium citrate-loaded C6 cells. These results indicate that baicalin down-regulated iron concentration, which positively regulat- ed divalent metal transporter 1 expression and negatively regulated ferroportin 1 expression, and decreased iron accumulation in the substantia nigra.
