As a novel paradigm,semantic communication provides an effective solution for breaking through the future development dilemma of classical communication systems.However,it remains an unsolved problem of how to measure...As a novel paradigm,semantic communication provides an effective solution for breaking through the future development dilemma of classical communication systems.However,it remains an unsolved problem of how to measure the information transmission capability for a given semantic communication method and subsequently compare it with the classical communication method.In this paper,we first present a review of the semantic communication system,including its system model and the two typical coding and transmission methods for its implementations.To address the unsolved issue of the information transmission capability measure for semantic communication methods,we propose a new universal performance measure called Information Conductivity.We provide the definition and the physical significance to state its effectiveness in representing the information transmission capabilities of the semantic communication systems and present elaborations including its measure methods,degrees of freedom,and progressive analysis.Experimental results in image transmission scenarios validate its practical applicability.展开更多
In this paper, we focus on the power allocation of Integrated Sensing and Communication(ISAC) with orthogonal frequency division multiplexing(OFDM) waveform. In order to improve the spectrum utilization efficiency in ...In this paper, we focus on the power allocation of Integrated Sensing and Communication(ISAC) with orthogonal frequency division multiplexing(OFDM) waveform. In order to improve the spectrum utilization efficiency in ISAC, we propose a design scheme based on spectrum sharing, that is,to maximize the mutual information(MI) of radar sensing while ensuring certain communication rate and transmission power constraints. In the proposed scheme, three cases are considered for the scattering off the target due to the communication signals,as negligible signal, beneficial signal, and interference signal to radar sensing, respectively, thus requiring three power allocation schemes. However,the corresponding power allocation schemes are nonconvex and their closed-form solutions are unavailable as a consequence. Motivated by this, alternating optimization(AO), sequence convex programming(SCP) and Lagrange multiplier are individually combined for three suboptimal solutions corresponding with three power allocation schemes. By combining the three algorithms, we transform the non-convex problem which is difficult to deal with into a convex problem which is easy to solve and obtain the suboptimal solution of the corresponding optimization problem. Numerical results show that, compared with the allocation results of the existing algorithms, the proposed joint design algorithm significantly improves the radar performance.展开更多
In this paper,the covert age of information(CAoI),which characterizes the timeliness and covertness performance of communication,is first investigated in the short-packet covert communication with time modulated retro...In this paper,the covert age of information(CAoI),which characterizes the timeliness and covertness performance of communication,is first investigated in the short-packet covert communication with time modulated retrodirective array(TMRDA).Specifically,the TMRDA is designed to maximize the antenna gain in the target direction while the side lobe is sufficiently suppressed.On this basis,the covertness constraint and CAoI are derived in closed form.To facilitate the covert transmission design,the transmit power and block-length are jointly optimized to minimize the CAoI,which demonstrates the trade-off between covertness and timelessness.Our results illustrate that there exists an optimal block-length that yields the minimum CAoI,and the presented optimization results can achieve enhanced performance compared with the fixed block-length case.Additionally,we observe that smaller beam pointing error at Bob leads to improvements in CAoI.展开更多
With the rapid development of information technology,5G communication technology has gradually entered real life,among which the application of edge computing is particularly significant in the information and communi...With the rapid development of information technology,5G communication technology has gradually entered real life,among which the application of edge computing is particularly significant in the information and communication system field.This paper focuses on using edge computing based on 5G communication in information and communication systems.First,the study analyzes the importance of combining edge computing technology with 5G communication technology,and its advantages,such as high efficiency and low latency in processing large amounts of data.The study then explores multiple application scenarios of edge computing in information and communication systems,such as integrated use in the Internet of Things,intelligent transportation,telemedicine and Industry 4.0.The research method is mainly based on theoretical analysis and experimental verification,combined with the characteristics of the 5G network to optimize the edge computing model and test the performance of edge computing in different scenarios through experimental simulation.The results show that edge computing significantly improves the data processing capacity and response speed of ICS in a 5G environment.However,there are also a series of challenges in practical application,including data security and privacy protection,the complexity of resource management and allocation,and the guarantee of quality of service(QoS).Through the case analysis and problem analysis,the paper puts forward the corresponding solution strategies,such as strengthening the data security protocol,introducing the intelligent resource scheduling system and establishing a multi-dimensional service quality monitoring mechanism.Finally,this study points out that the deep integration of edge computing and 5G communication will continue to promote the innovative development of information and communication systems,which has a far-reaching impact and important practical significance for promoting the transformation and upgrading in the field of information technology.展开更多
BACKGROUND Acute liver failure(ALF)has a high mortality with widespread hepatocyte death involving ferroptosis and pyroptosis.The silent information regulator sirtuin 1(SIRT1)-mediated deacetylation affects multiple b...BACKGROUND Acute liver failure(ALF)has a high mortality with widespread hepatocyte death involving ferroptosis and pyroptosis.The silent information regulator sirtuin 1(SIRT1)-mediated deacetylation affects multiple biological processes,including cellular senescence,apoptosis,sugar and lipid metabolism,oxidative stress,and inflammation.AIM To investigate the association between ferroptosis and pyroptosis and the upstream regulatory mechanisms.METHODS This study included 30 patients with ALF and 30 healthy individuals who underwent serum alanine aminotransferase(ALT)and aspartate aminotransferase(AST)testing.C57BL/6 mice were also intraperitoneally pretreated with SIRT1,p53,or glutathione peroxidase 4(GPX4)inducers and inhibitors and injected with lipopolysaccharide(LPS)/D-galactosamine(D-GalN)to induce ALF.Gasdermin D(GSDMD)^(-/-)mice were used as an experimental group.Histological changes in liver tissue were monitored by hematoxylin and eosin staining.ALT,AST,glutathione,reactive oxygen species,and iron levels were measured using commercial kits.Ferroptosis-and pyroptosis-related protein and mRNA expression was detected by western blot and quantitative real-time polymerase chain reaction.SIRT1,p53,and GSDMD were assessed by immunofluorescence analysis.RESULTS Serum AST and ALT levels were elevated in patients with ALF.SIRT1,solute carrier family 7a member 11(SLC7A11),and GPX4 protein expression was decreased and acetylated p5,p53,GSDMD,and acyl-CoA synthetase long-chain family member 4(ACSL4)protein levels were elevated in human ALF liver tissue.In the p53 and ferroptosis inhibitor-treated and GSDMD^(-/-)groups,serum interleukin(IL)-1β,tumour necrosis factor alpha,IL-6,IL-2 and C-C motif ligand 2 levels were decreased and hepatic impairment was mitigated.In mice with GSDMD knockout,p53 was reduced,GPX4 was increased,and ferroptotic events(depletion of SLC7A11,elevation of ACSL4,and iron accumulation)were detected.In vitro,knockdown of p53 and overexpression of GPX4 reduced AST and ALT levels,the cytostatic rate,and GSDMD expression,restoring SLC7A11 depletion.Moreover,SIRT1 agonist and overexpression of SIRT1 alleviated acute liver injury and decreased iron deposition compared with results in the model group,accompanied by reduced p53,GSDMD,and ACSL4,and increased SLC7A11 and GPX4.Inactivation of SIRT1 exacerbated ferroptotic and pyroptotic cell death and aggravated liver injury in LPS/D-GalNinduced in vitro and in vivo models.CONCLUSION SIRT1 activation attenuates LPS/D-GalN-induced ferroptosis and pyroptosis by inhibiting the p53/GPX4/GSDMD signaling pathway in ALF.展开更多
While the increasing development of modern information technology, the globalization is becoming an obvious feature on educational situations. Therefore, mastering some necessary bilingual competencies will present es...While the increasing development of modern information technology, the globalization is becoming an obvious feature on educational situations. Therefore, mastering some necessary bilingual competencies will present essential meaning for educators. In the case of language teachers who teaching in the ethnically plural countries, for instance, China, the United States, language teachers have to face to various difficulties on the process of teaching in the bilingual class. Currently, the advanced technology is gradually being applied into language teaching, and then provides a series of advantages on improving the quality of language teaching. Firstly, the essay will analyse the barriers which exist in the language class, which in the level of Chinese university. Secondly, it will systematically describe how ICT can help language teachers to solve difficulties on teaching and display diverse innovative technological tools of language teaching.展开更多
Although a large number of studies have focused on various aspects of politeness,very little is known about how politeness intention is activated cognitively during verbal communication.The present study aims to explo...Although a large number of studies have focused on various aspects of politeness,very little is known about how politeness intention is activated cognitively during verbal communication.The present study aims to explore the cognitive mechanism of politeness intention processing,and how it is related to pragmatic failure during cross-cultural communication.Using 30 Chinese EFL university students who were instructed to finish a probe word judgment task with 96 virtual scenarios,the results indicate that within both mono-and cross-cultural contexts,the response time in the experimental scenarios was significantly slower than that of the filler scenarios.This suggests that politeness intention was activated while understanding the surface meaning of the conversation;however,the EFL learners could not completely avoid the negative transfer of their native politeness conventions when they were comprehending the conversational intention of the target language.Furthermore,no significant differences in response time were found between the groups with high and low English pragmatic competence,illustrating that transferring the pragmatic rules and principles into cross-cultural communication skills was more cognitively demanding.Overall,this study adds to the literature on politeness research and provides some implications for foreign language pragmatic instructions.展开更多
There is tremendous growth in the use of Geographic Information Systems(GIS), Global Positioning Systems (GPS), Remote Sensing, Satellite Communication, andModeling & Simulation techniques.These tools and techniqu...There is tremendous growth in the use of Geographic Information Systems(GIS), Global Positioning Systems (GPS), Remote Sensing, Satellite Communication, andModeling & Simulation techniques.These tools and techniques helps significantly in characterizinginfrastructure, risk area and disaster zones, planning and implementation ofhazards reduction measures etc.Communication satellites becomes vital for providingemergency communication and timely relief measures.Integration of space technologyinputs into natural disaster monitoring and mitigation mechanisms is critical for hazard reduction.This paper mainly focused on all the issues described above.Major emphasis hadbeen given to the recent developments in information & communication technology enabledtools and their applications in mining industries for safe mining operations with increasedproductivity.展开更多
Communities in developing country mountain areas,in part due to their remoteness,find themselves excluded from social,political and economic systems; and excluded from access to resources. This paper aims to study the...Communities in developing country mountain areas,in part due to their remoteness,find themselves excluded from social,political and economic systems; and excluded from access to resources. This paper aims to study the impact of information and communication technologies (ICTs) on remoteness and exclusion. It utilises two models - the resource movement framework,and the "information chain" - to analyse a telecentre in one district of mountainous Huancavelica,Peru's poorest region,set in the high Andes. It finds ICTs enabling new and positive resource flows for the two key user groups:teenaged school students and young farmers. These help to maintain social networks. They also support information searches that have improved agricultural practice where other information chain resources have been available. But non-use and ineffective use of the telecentre are found where information chain resources are lacking. ICTs have some impacts on intangible elements of remoteness. In this particular example,they also offer access to some previously-excluded resources. But they have not really addressed the systematic exclusions faced by mountain communities. And they so far appear to be a technology of inequality; favouring those residents who begin with better resource endowments.The paper concludes by offering some recommendations for mountain ICT project practice.展开更多
In order to forecast promising technologies in the field of next generation mobile communication, various patent indicators were analyzed such as citation per patent, patent family information, patent share, increase ...In order to forecast promising technologies in the field of next generation mobile communication, various patent indicators were analyzed such as citation per patent, patent family information, patent share, increase rate, and patent activity. These indicators were quantified into several indexes and then integrated into an evaluation score to provide promising technologies. As a result of the suggested patent analysis, four technologies out of twenty two in details classification were selected, which showed outstanding technology competitiveness, high patent share and increasing rates as well as high recent-patent-ratios and triad-patent-family-ratios. Each of the selected technologies scored more than 10 points in total, and the following four technologies were suggested as promising ones in the field of next generation mobile communication: 1) 3GPP based mobile communication, 2) beyond 4G mobile communication, 3) IEEE 802.16 based mobile communication, which are in medium classification of broadband mobile communication system, and 4) testing/certification system of mobile communication, which is in medium classification of mobile communication testing/certification system.展开更多
The paper aims to study the current communication condition,configuration,characteristic and regulation of Chinese agricultural information in terms of the eyeshot of communication studies,and provide reference to bui...The paper aims to study the current communication condition,configuration,characteristic and regulation of Chinese agricultural information in terms of the eyeshot of communication studies,and provide reference to build Chinese agricultural information service system based on the analysis of their advantages and disadvantages.展开更多
Visible Light Communication( VLC) based on LED is a new wireless communication technology with high response rate and good modulation characteristics in the wavelengths of 380- 780 nm. Compared with conventional metho...Visible Light Communication( VLC) based on LED is a new wireless communication technology with high response rate and good modulation characteristics in the wavelengths of 380- 780 nm. Compared with conventional methods,the waveband of VLC is harmless to human and safe to communication because of no magnetism radiation. An audio information transmission system using LED traffic lights is presented based on VLC technology. The system is consisted of transmitting terminal,receiving terminal and communication channel. Some experiments were made under real communication environment. The experimental results showed that the traffic information transmission system works steadily with good communication quality and achieves the purpose of transmitting audio information through LED traffic lights,with a data transfer rate up to 250 kbps over a distance of 5 meters.展开更多
In the intercultural communication, people often ignore the nonverbal behavior when they talk to others. With the raid progress of modern traffic and tools of communication, people’s contacts have become increasingly...In the intercultural communication, people often ignore the nonverbal behavior when they talk to others. With the raid progress of modern traffic and tools of communication, people’s contacts have become increasingly frequent with different regions and countries. The research on pragmatic failures in nonverbal communication allows people to understand its nature and eliminate some unnecessary misunderstanding. This paper aims at finding out the root causes about pragmatic failures in nonverbal communication in the intercultural communication, and providing several sensible recommendations.展开更多
Map is one of the communication means created by human being.Cartographers have been making efforts on the comparison of maps to natural languages so as to establish a"cartographic language"or"map langu...Map is one of the communication means created by human being.Cartographers have been making efforts on the comparison of maps to natural languages so as to establish a"cartographic language"or"map language".One of such efforts is to adopt the Shannon’s Information Theory originated in digital communication into cartography so as to establish an entropy-based cartographic communication theory.However,success has been very limited although research work had started as early as the mid-1960 s.It is then found that the bottleneck problem was the lack of appropriate measures for the spatial(configurational)information of(graphic and image)maps,as the classic Shannon entropy is only capable of characterizing statistical information but fails to capture the configurational information of(graphic and image)maps.Fortunately,after over 40-year development,some bottleneck problems have been solved.More precisely,generalized Shannon entropies for metric and thematic information of(graphic)maps have been developed and the first feasible solution for computing the Boltzmann entropy of image maps has been invented,which is capable of measuring the spatial information of not only numerical images but also categorical maps.With such progress,it is now feasible to build the"Information Theory of Cartography".In this paper,a framework for such a theory is proposed and some key issues are identified.For these issues,some have already been tackled while others still need efforts.As a result,a research agenda is set for future action.After all these issues are tackled,the theory will become matured so as to become a theoretic basis of cartography.It is expected that the Information Theory of Cartography will play an increasingly important role in the discipline of cartography because more and more researchers have advocated that information is more fundamental than matter and energy.展开更多
This paper focuses on pragmatic failures in cross-cultural communication and explores the difficult meanings in cross-cultural pragmatics. Through exploring the differences in address, greeting, politeness and other c...This paper focuses on pragmatic failures in cross-cultural communication and explores the difficult meanings in cross-cultural pragmatics. Through exploring the differences in address, greeting, politeness and other cross-cultural aspects, the author explains the cross-cultural basis for pragmatics. The author first explains certain concepts, including culture, pragmatics, pragmatic failures and cross-cultural communication, and then illustrates some pragmatic failures in cross-cultural communication and discusses the causes of these failures. Finally, she gives some suggestions on improving competence in cross-cultural communication. This thesis is intended to remind English learners of the importance of learning cultures of English-speaking countries and facilitate cross-cultural communication.展开更多
User influence is generally considered as one of the most critical factors that affect information cascading spreading. Based on this common assumption, this paper proposes a theoretical model to examine user influenc...User influence is generally considered as one of the most critical factors that affect information cascading spreading. Based on this common assumption, this paper proposes a theoretical model to examine user influence on the information multi-step communication in a micro-biog. The multi-steps of information communication are divided into first-step and non-first-step, and user influence is classified into five dimensions. Actual data from the Sina micro-blog is collected to construct the model by means of an approach based on structural equations that uses the Partial Least Squares (PLS) technique. Our experimental results indicate that the dimensions of the number of fans and their authority significantly impact the information of first-step conxrnunication. Leader rank has a positive impact on both first-step and non-first-step communication. Moreover, global centrality and weight of friends are positively related to the information non-first-step communication, but authority is found to have much less relation to it.展开更多
As a form of a future traffic system,a connected and automated vehicle(CAV)platoon is a typical nonlinear physical system.CAVs can communicate with each other and exchange information.However,communication failures ca...As a form of a future traffic system,a connected and automated vehicle(CAV)platoon is a typical nonlinear physical system.CAVs can communicate with each other and exchange information.However,communication failures can change the platoon system status.To characterize this change,a dynamic topology-based car-following model and its generalized form are proposed in this work.Then,a stability analysis method is explored.Finally,taking the dynamic cooperative intelligent driver model(DC-IDM)for example,a series of numerical simulations is conducted to analyze the platoon stability in different communication topology scenarios.The results show that the communication failures reduce the stability,but information from vehicles that are farther ahead and the use of a larger desired time headway can improve stability.Moreover,the critical ratio of communication failures required to ensure stability for different driving parameters is studied in this work.展开更多
The concept of rough communication based on both-branch fuzzy set is proposed, in which the loss of information may exist, for each agent there has a different language and can not provide precise communication to eac...The concept of rough communication based on both-branch fuzzy set is proposed, in which the loss of information may exist, for each agent there has a different language and can not provide precise communication to each other. The method of information measure in a rough communication based on both-branch fuzzy set is proposed. By using some concepts, such as |α|-both-branch rough communication cut, the relation theorem between rough communication based on both-branch fuzzy concept and rough communication based on classical concept is obtained. Finally, an example of rough communication based on both-branch fuzzy set is given.展开更多
The general goal of the management of communication and information technology (MCIT) in the health sector, is to accelerate collecting, achieving and supporting the health system processes, and effective decision-mak...The general goal of the management of communication and information technology (MCIT) in the health sector, is to accelerate collecting, achieving and supporting the health system processes, and effective decision-making for managing this system;because preparing and providing health care services for society is very complex, and highly dependent on the information system. The aim of this investigation is to determine the mean scores of the possibility of implementing the MCIT standards in Khorasan Razavi hospitals, from the perspective of managers. This was a cross sectional descriptive-analytic study conducted in two steps in all hospitals. In the first step, the applicability of the standards in hospitals was studied. In the second step, the current status of hospitals was compared with international standards MCIT. In order to determine the validity of the questionnaires, opinions of professors and experts were acquired. Regarding the reliability, the SPSS V. 12 calculated the value of Cronbach’s to be 0.95 for the first questionnaire and 0.86 for the second questionnaire. Data were analyzed using statistic tests of one way ANOVA and t-test. The level of significance was fixed at 0.5. In the 16 hospitals studied, the mean and standard deviation of MCIT were (57.25 ± 13.74). The MCIT standards are applicable in hospitals of Khorasan Razavi according to half (49.4%) of managers;nonetheless, their application requires greater efforts by the hospitals.展开更多
The proposed secure communication approach adopts the proposed algorithm of Analysis-By- Synthesis (ABS) speech information hiding to establish a Secret Speech Subliminai Channel (SSSC) for speech secure communica...The proposed secure communication approach adopts the proposed algorithm of Analysis-By- Synthesis (ABS) speech information hiding to establish a Secret Speech Subliminai Channel (SSSC) for speech secure communication over PSTN (Public Switched Telephone Network), and employs the algorithm of ABS speech information extracting to recovery the secret information, This approach is more reliable, covert and securable than traditional and chaotic secure communication.展开更多
基金supported by the National Natural Science Foundation of China(No.62293481,No.62071058)。
文摘As a novel paradigm,semantic communication provides an effective solution for breaking through the future development dilemma of classical communication systems.However,it remains an unsolved problem of how to measure the information transmission capability for a given semantic communication method and subsequently compare it with the classical communication method.In this paper,we first present a review of the semantic communication system,including its system model and the two typical coding and transmission methods for its implementations.To address the unsolved issue of the information transmission capability measure for semantic communication methods,we propose a new universal performance measure called Information Conductivity.We provide the definition and the physical significance to state its effectiveness in representing the information transmission capabilities of the semantic communication systems and present elaborations including its measure methods,degrees of freedom,and progressive analysis.Experimental results in image transmission scenarios validate its practical applicability.
文摘In this paper, we focus on the power allocation of Integrated Sensing and Communication(ISAC) with orthogonal frequency division multiplexing(OFDM) waveform. In order to improve the spectrum utilization efficiency in ISAC, we propose a design scheme based on spectrum sharing, that is,to maximize the mutual information(MI) of radar sensing while ensuring certain communication rate and transmission power constraints. In the proposed scheme, three cases are considered for the scattering off the target due to the communication signals,as negligible signal, beneficial signal, and interference signal to radar sensing, respectively, thus requiring three power allocation schemes. However,the corresponding power allocation schemes are nonconvex and their closed-form solutions are unavailable as a consequence. Motivated by this, alternating optimization(AO), sequence convex programming(SCP) and Lagrange multiplier are individually combined for three suboptimal solutions corresponding with three power allocation schemes. By combining the three algorithms, we transform the non-convex problem which is difficult to deal with into a convex problem which is easy to solve and obtain the suboptimal solution of the corresponding optimization problem. Numerical results show that, compared with the allocation results of the existing algorithms, the proposed joint design algorithm significantly improves the radar performance.
文摘In this paper,the covert age of information(CAoI),which characterizes the timeliness and covertness performance of communication,is first investigated in the short-packet covert communication with time modulated retrodirective array(TMRDA).Specifically,the TMRDA is designed to maximize the antenna gain in the target direction while the side lobe is sufficiently suppressed.On this basis,the covertness constraint and CAoI are derived in closed form.To facilitate the covert transmission design,the transmit power and block-length are jointly optimized to minimize the CAoI,which demonstrates the trade-off between covertness and timelessness.Our results illustrate that there exists an optimal block-length that yields the minimum CAoI,and the presented optimization results can achieve enhanced performance compared with the fixed block-length case.Additionally,we observe that smaller beam pointing error at Bob leads to improvements in CAoI.
文摘With the rapid development of information technology,5G communication technology has gradually entered real life,among which the application of edge computing is particularly significant in the information and communication system field.This paper focuses on using edge computing based on 5G communication in information and communication systems.First,the study analyzes the importance of combining edge computing technology with 5G communication technology,and its advantages,such as high efficiency and low latency in processing large amounts of data.The study then explores multiple application scenarios of edge computing in information and communication systems,such as integrated use in the Internet of Things,intelligent transportation,telemedicine and Industry 4.0.The research method is mainly based on theoretical analysis and experimental verification,combined with the characteristics of the 5G network to optimize the edge computing model and test the performance of edge computing in different scenarios through experimental simulation.The results show that edge computing significantly improves the data processing capacity and response speed of ICS in a 5G environment.However,there are also a series of challenges in practical application,including data security and privacy protection,the complexity of resource management and allocation,and the guarantee of quality of service(QoS).Through the case analysis and problem analysis,the paper puts forward the corresponding solution strategies,such as strengthening the data security protocol,introducing the intelligent resource scheduling system and establishing a multi-dimensional service quality monitoring mechanism.Finally,this study points out that the deep integration of edge computing and 5G communication will continue to promote the innovative development of information and communication systems,which has a far-reaching impact and important practical significance for promoting the transformation and upgrading in the field of information technology.
基金Supported by National Natural Science Foundation of China,No.82060123Doctoral Start-up Fund of Affiliated Hospital of Guizhou Medical University,No.gysybsky-2021-28+1 种基金Fund Project of Guizhou Provincial Science and Technology Department,No.[2020]1Y299Guizhou Provincial Health Commission,No.gzwjk2019-1-082。
文摘BACKGROUND Acute liver failure(ALF)has a high mortality with widespread hepatocyte death involving ferroptosis and pyroptosis.The silent information regulator sirtuin 1(SIRT1)-mediated deacetylation affects multiple biological processes,including cellular senescence,apoptosis,sugar and lipid metabolism,oxidative stress,and inflammation.AIM To investigate the association between ferroptosis and pyroptosis and the upstream regulatory mechanisms.METHODS This study included 30 patients with ALF and 30 healthy individuals who underwent serum alanine aminotransferase(ALT)and aspartate aminotransferase(AST)testing.C57BL/6 mice were also intraperitoneally pretreated with SIRT1,p53,or glutathione peroxidase 4(GPX4)inducers and inhibitors and injected with lipopolysaccharide(LPS)/D-galactosamine(D-GalN)to induce ALF.Gasdermin D(GSDMD)^(-/-)mice were used as an experimental group.Histological changes in liver tissue were monitored by hematoxylin and eosin staining.ALT,AST,glutathione,reactive oxygen species,and iron levels were measured using commercial kits.Ferroptosis-and pyroptosis-related protein and mRNA expression was detected by western blot and quantitative real-time polymerase chain reaction.SIRT1,p53,and GSDMD were assessed by immunofluorescence analysis.RESULTS Serum AST and ALT levels were elevated in patients with ALF.SIRT1,solute carrier family 7a member 11(SLC7A11),and GPX4 protein expression was decreased and acetylated p5,p53,GSDMD,and acyl-CoA synthetase long-chain family member 4(ACSL4)protein levels were elevated in human ALF liver tissue.In the p53 and ferroptosis inhibitor-treated and GSDMD^(-/-)groups,serum interleukin(IL)-1β,tumour necrosis factor alpha,IL-6,IL-2 and C-C motif ligand 2 levels were decreased and hepatic impairment was mitigated.In mice with GSDMD knockout,p53 was reduced,GPX4 was increased,and ferroptotic events(depletion of SLC7A11,elevation of ACSL4,and iron accumulation)were detected.In vitro,knockdown of p53 and overexpression of GPX4 reduced AST and ALT levels,the cytostatic rate,and GSDMD expression,restoring SLC7A11 depletion.Moreover,SIRT1 agonist and overexpression of SIRT1 alleviated acute liver injury and decreased iron deposition compared with results in the model group,accompanied by reduced p53,GSDMD,and ACSL4,and increased SLC7A11 and GPX4.Inactivation of SIRT1 exacerbated ferroptotic and pyroptotic cell death and aggravated liver injury in LPS/D-GalNinduced in vitro and in vivo models.CONCLUSION SIRT1 activation attenuates LPS/D-GalN-induced ferroptosis and pyroptosis by inhibiting the p53/GPX4/GSDMD signaling pathway in ALF.
文摘While the increasing development of modern information technology, the globalization is becoming an obvious feature on educational situations. Therefore, mastering some necessary bilingual competencies will present essential meaning for educators. In the case of language teachers who teaching in the ethnically plural countries, for instance, China, the United States, language teachers have to face to various difficulties on the process of teaching in the bilingual class. Currently, the advanced technology is gradually being applied into language teaching, and then provides a series of advantages on improving the quality of language teaching. Firstly, the essay will analyse the barriers which exist in the language class, which in the level of Chinese university. Secondly, it will systematically describe how ICT can help language teachers to solve difficulties on teaching and display diverse innovative technological tools of language teaching.
文摘Although a large number of studies have focused on various aspects of politeness,very little is known about how politeness intention is activated cognitively during verbal communication.The present study aims to explore the cognitive mechanism of politeness intention processing,and how it is related to pragmatic failure during cross-cultural communication.Using 30 Chinese EFL university students who were instructed to finish a probe word judgment task with 96 virtual scenarios,the results indicate that within both mono-and cross-cultural contexts,the response time in the experimental scenarios was significantly slower than that of the filler scenarios.This suggests that politeness intention was activated while understanding the surface meaning of the conversation;however,the EFL learners could not completely avoid the negative transfer of their native politeness conventions when they were comprehending the conversational intention of the target language.Furthermore,no significant differences in response time were found between the groups with high and low English pragmatic competence,illustrating that transferring the pragmatic rules and principles into cross-cultural communication skills was more cognitively demanding.Overall,this study adds to the literature on politeness research and provides some implications for foreign language pragmatic instructions.
文摘There is tremendous growth in the use of Geographic Information Systems(GIS), Global Positioning Systems (GPS), Remote Sensing, Satellite Communication, andModeling & Simulation techniques.These tools and techniques helps significantly in characterizinginfrastructure, risk area and disaster zones, planning and implementation ofhazards reduction measures etc.Communication satellites becomes vital for providingemergency communication and timely relief measures.Integration of space technologyinputs into natural disaster monitoring and mitigation mechanisms is critical for hazard reduction.This paper mainly focused on all the issues described above.Major emphasis hadbeen given to the recent developments in information & communication technology enabledtools and their applications in mining industries for safe mining operations with increasedproductivity.
基金a grant from the International Development Research Centre, Canada, and Microsoft Corporationsupport of the Seminario Permanente de Investigacion Agraria (Permanent Seminar on Agricultural Research), SEPIA
文摘Communities in developing country mountain areas,in part due to their remoteness,find themselves excluded from social,political and economic systems; and excluded from access to resources. This paper aims to study the impact of information and communication technologies (ICTs) on remoteness and exclusion. It utilises two models - the resource movement framework,and the "information chain" - to analyse a telecentre in one district of mountainous Huancavelica,Peru's poorest region,set in the high Andes. It finds ICTs enabling new and positive resource flows for the two key user groups:teenaged school students and young farmers. These help to maintain social networks. They also support information searches that have improved agricultural practice where other information chain resources have been available. But non-use and ineffective use of the telecentre are found where information chain resources are lacking. ICTs have some impacts on intangible elements of remoteness. In this particular example,they also offer access to some previously-excluded resources. But they have not really addressed the systematic exclusions faced by mountain communities. And they so far appear to be a technology of inequality; favouring those residents who begin with better resource endowments.The paper concludes by offering some recommendations for mountain ICT project practice.
文摘In order to forecast promising technologies in the field of next generation mobile communication, various patent indicators were analyzed such as citation per patent, patent family information, patent share, increase rate, and patent activity. These indicators were quantified into several indexes and then integrated into an evaluation score to provide promising technologies. As a result of the suggested patent analysis, four technologies out of twenty two in details classification were selected, which showed outstanding technology competitiveness, high patent share and increasing rates as well as high recent-patent-ratios and triad-patent-family-ratios. Each of the selected technologies scored more than 10 points in total, and the following four technologies were suggested as promising ones in the field of next generation mobile communication: 1) 3GPP based mobile communication, 2) beyond 4G mobile communication, 3) IEEE 802.16 based mobile communication, which are in medium classification of broadband mobile communication system, and 4) testing/certification system of mobile communication, which is in medium classification of mobile communication testing/certification system.
基金Supported by the Basic Scientific Research Special Item of Central Commonweal Scientific Institution (0032009023)~~
文摘The paper aims to study the current communication condition,configuration,characteristic and regulation of Chinese agricultural information in terms of the eyeshot of communication studies,and provide reference to build Chinese agricultural information service system based on the analysis of their advantages and disadvantages.
基金Sponsored by the National Science and Technology Innovation Fund for Small and Medium Enterprises(Grant No.10C26211200144)Tianjin Science and Technology Key Supporting Projects(Grant No.10ZCGYGX18300)
文摘Visible Light Communication( VLC) based on LED is a new wireless communication technology with high response rate and good modulation characteristics in the wavelengths of 380- 780 nm. Compared with conventional methods,the waveband of VLC is harmless to human and safe to communication because of no magnetism radiation. An audio information transmission system using LED traffic lights is presented based on VLC technology. The system is consisted of transmitting terminal,receiving terminal and communication channel. Some experiments were made under real communication environment. The experimental results showed that the traffic information transmission system works steadily with good communication quality and achieves the purpose of transmitting audio information through LED traffic lights,with a data transfer rate up to 250 kbps over a distance of 5 meters.
文摘In the intercultural communication, people often ignore the nonverbal behavior when they talk to others. With the raid progress of modern traffic and tools of communication, people’s contacts have become increasingly frequent with different regions and countries. The research on pragmatic failures in nonverbal communication allows people to understand its nature and eliminate some unnecessary misunderstanding. This paper aims at finding out the root causes about pragmatic failures in nonverbal communication in the intercultural communication, and providing several sensible recommendations.
基金National Natural Science Foundation of China(Nos.41930104,41971330)Hong Kong Research Grants Council General Research Fund(No.152219/18E)。
文摘Map is one of the communication means created by human being.Cartographers have been making efforts on the comparison of maps to natural languages so as to establish a"cartographic language"or"map language".One of such efforts is to adopt the Shannon’s Information Theory originated in digital communication into cartography so as to establish an entropy-based cartographic communication theory.However,success has been very limited although research work had started as early as the mid-1960 s.It is then found that the bottleneck problem was the lack of appropriate measures for the spatial(configurational)information of(graphic and image)maps,as the classic Shannon entropy is only capable of characterizing statistical information but fails to capture the configurational information of(graphic and image)maps.Fortunately,after over 40-year development,some bottleneck problems have been solved.More precisely,generalized Shannon entropies for metric and thematic information of(graphic)maps have been developed and the first feasible solution for computing the Boltzmann entropy of image maps has been invented,which is capable of measuring the spatial information of not only numerical images but also categorical maps.With such progress,it is now feasible to build the"Information Theory of Cartography".In this paper,a framework for such a theory is proposed and some key issues are identified.For these issues,some have already been tackled while others still need efforts.As a result,a research agenda is set for future action.After all these issues are tackled,the theory will become matured so as to become a theoretic basis of cartography.It is expected that the Information Theory of Cartography will play an increasingly important role in the discipline of cartography because more and more researchers have advocated that information is more fundamental than matter and energy.
文摘This paper focuses on pragmatic failures in cross-cultural communication and explores the difficult meanings in cross-cultural pragmatics. Through exploring the differences in address, greeting, politeness and other cross-cultural aspects, the author explains the cross-cultural basis for pragmatics. The author first explains certain concepts, including culture, pragmatics, pragmatic failures and cross-cultural communication, and then illustrates some pragmatic failures in cross-cultural communication and discusses the causes of these failures. Finally, she gives some suggestions on improving competence in cross-cultural communication. This thesis is intended to remind English learners of the importance of learning cultures of English-speaking countries and facilitate cross-cultural communication.
基金supported by the National Natural Science Foundation of China(Grant No.60873246)China Information Technology Security Evaluation Center
文摘User influence is generally considered as one of the most critical factors that affect information cascading spreading. Based on this common assumption, this paper proposes a theoretical model to examine user influence on the information multi-step communication in a micro-biog. The multi-steps of information communication are divided into first-step and non-first-step, and user influence is classified into five dimensions. Actual data from the Sina micro-blog is collected to construct the model by means of an approach based on structural equations that uses the Partial Least Squares (PLS) technique. Our experimental results indicate that the dimensions of the number of fans and their authority significantly impact the information of first-step conxrnunication. Leader rank has a positive impact on both first-step and non-first-step communication. Moreover, global centrality and weight of friends are positively related to the information non-first-step communication, but authority is found to have much less relation to it.
基金Project supported by the National Key Research and Development Project of China(Grant No.2018YFE0204300)the Beijing Municipal Science&Technology Commission(Grant No.Z211100004221008)the National Natural Science Foundation of China(Grant No.U1964206).
文摘As a form of a future traffic system,a connected and automated vehicle(CAV)platoon is a typical nonlinear physical system.CAVs can communicate with each other and exchange information.However,communication failures can change the platoon system status.To characterize this change,a dynamic topology-based car-following model and its generalized form are proposed in this work.Then,a stability analysis method is explored.Finally,taking the dynamic cooperative intelligent driver model(DC-IDM)for example,a series of numerical simulations is conducted to analyze the platoon stability in different communication topology scenarios.The results show that the communication failures reduce the stability,but information from vehicles that are farther ahead and the use of a larger desired time headway can improve stability.Moreover,the critical ratio of communication failures required to ensure stability for different driving parameters is studied in this work.
基金supported by the National Natural Science Foundation of China (61070241)the Natural Science Foundation of Shandong Province (ZR2010 FM035)the Science Research Foundation of University of Jinan (XKYK31)
文摘The concept of rough communication based on both-branch fuzzy set is proposed, in which the loss of information may exist, for each agent there has a different language and can not provide precise communication to each other. The method of information measure in a rough communication based on both-branch fuzzy set is proposed. By using some concepts, such as |α|-both-branch rough communication cut, the relation theorem between rough communication based on both-branch fuzzy concept and rough communication based on classical concept is obtained. Finally, an example of rough communication based on both-branch fuzzy set is given.
文摘The general goal of the management of communication and information technology (MCIT) in the health sector, is to accelerate collecting, achieving and supporting the health system processes, and effective decision-making for managing this system;because preparing and providing health care services for society is very complex, and highly dependent on the information system. The aim of this investigation is to determine the mean scores of the possibility of implementing the MCIT standards in Khorasan Razavi hospitals, from the perspective of managers. This was a cross sectional descriptive-analytic study conducted in two steps in all hospitals. In the first step, the applicability of the standards in hospitals was studied. In the second step, the current status of hospitals was compared with international standards MCIT. In order to determine the validity of the questionnaires, opinions of professors and experts were acquired. Regarding the reliability, the SPSS V. 12 calculated the value of Cronbach’s to be 0.95 for the first questionnaire and 0.86 for the second questionnaire. Data were analyzed using statistic tests of one way ANOVA and t-test. The level of significance was fixed at 0.5. In the 16 hospitals studied, the mean and standard deviation of MCIT were (57.25 ± 13.74). The MCIT standards are applicable in hospitals of Khorasan Razavi according to half (49.4%) of managers;nonetheless, their application requires greater efforts by the hospitals.
基金Supported by the National High Technology Research and Development Program of China (863 Program) (No.2003AA142080, 2004AA775060)the National Natural Sicence Foundation of China (No.60203004)+1 种基金with additional support from the China Post-doctorial Research Foundation (2005-03)the Foundation of Tianjin Key Lab for Advanced Signal Processing(2005).
文摘The proposed secure communication approach adopts the proposed algorithm of Analysis-By- Synthesis (ABS) speech information hiding to establish a Secret Speech Subliminai Channel (SSSC) for speech secure communication over PSTN (Public Switched Telephone Network), and employs the algorithm of ABS speech information extracting to recovery the secret information, This approach is more reliable, covert and securable than traditional and chaotic secure communication.