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Detoxification of toxic herbs in TCM prescription based on modulation of efflux transporters
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作者 QIAN Liyunhe HE Yufei +1 位作者 ZHANG Mei XIE Ying 《Digital Chinese Medicine》 2021年第1期9-18,共10页
Traditional Chinese medicines(TCMs)have been used to prevent and treat various diseases for thousands of years.Promoting efficacy and reducing toxicity by the compatibility theory of TCMs has attracted increasing atte... Traditional Chinese medicines(TCMs)have been used to prevent and treat various diseases for thousands of years.Promoting efficacy and reducing toxicity by the compatibility theory of TCMs has attracted increasing attention,especially for the toxicity of herbs.Studies have pointed out the interactions between the active compounds of herbs and transporters in the detoxification process of toxic compounds.Here,we summarize data on five toxic herbs commonly used in TCMs and their related efflux transporters to reduce toxicity to offer a scientific rationale for the compatibility principle of TCMs and provide guidance for the rational clinical use of TCMs. 展开更多
关键词 Toxic herbs Efflux transporters DETOXIFICATION TCMs compatibility principles P-glycoprotein(P-gp)
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New Analysis of Banxia Xiexin Decoction and Its Similar Prescriptions in Treatise on Febrile Diseases to Explore the Universality of the Treatment and Compatibility Principle 被引量:1
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作者 Ren-Ling Wei Zheng-Feng Li +4 位作者 Ru-Sen Cao Jian-Bin Zeng Jian-Li Shen Qiu-Lan Pei Qi-Jun Liang 《World Journal of Traditional Chinese Medicine》 CAS 2022年第4期509-513,共5页
Objective:The objective of this study is to explore the treatment and compatibility principles of Traditional Chinese Medicine.Materials and Methods:Syndrome differentiation is used to identify the etiology,nature,and... Objective:The objective of this study is to explore the treatment and compatibility principles of Traditional Chinese Medicine.Materials and Methods:Syndrome differentiation is used to identify the etiology,nature,and location of a disease and the relationship between the healthy Qi and pathogenic factors by analyzing and synthesizing the four diagnostics data.The theory of treatment is to determine the principle and methods of treatment according to the results of syndrome differentiation and implement them as a specific prescription.This paper bears witness to the principle universality by analysis of the articles of the Banxia Xiexin Decoction,and it equally has analogical prescriptions in Treatise on Febrile Diseases.Results:The treatment and compatibility principles of Traditional Chinese Medicine are the same,that is,rectifying the deviation on three dimensions,strengthening the healthy Qi,and eliminating pathogenic factors in the light of its general trend.Conclusion:The treatment and compatibility principles of Traditional Chinese Medicine are the same,The treatment and compatibility principles provide a new thinking for clinical treatment. 展开更多
关键词 Banxia Xiexin Decoction compatibility principle eliminating pathogenic factors strengthening the healthy Qi therapeutic principle three dimensions treatment and compatibility principle
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