[Objectives] Volatile oil components of traditional drug use site " root and rhizome" of N. jatamansi and herb were identified and contrasted,which aimed to provide the basis for rationally using wild N. jat...[Objectives] Volatile oil components of traditional drug use site " root and rhizome" of N. jatamansi and herb were identified and contrasted,which aimed to provide the basis for rationally using wild N. jatamansi resource. [Methods]Volatile oil components from different sites of N. jatamansi were identified and isolated by GC-MS. [Results] There were 56 kinds of volatile oil components from different sites of N. jatamansi,in which 39 components from herb of N. jatamansi,39 components from root and rhizome of N. jatamansi,and there were 22 common components. But 1 component in higher concentration had obvious difference. [Conclusions] The herb of N. jatamansi could not completely replace " root and rhizome" of N. jatamansi as the medicine,which was consistent with prior detection result of each physicochemical index from different sites of N. jatamansi. The research could provide the reference for making quality standard of N. jatamansi medicine and rational basis for its further research and development.展开更多
[Objectives]To establish the HPLC-DAD fingerprint of Xueshuan Xinmaining Capsule(XXC).[Methods]The chromatographic conditions for the analysis of XXC solution were as follows:XSelect HSS T3 column;acetonitrile-0.1%pho...[Objectives]To establish the HPLC-DAD fingerprint of Xueshuan Xinmaining Capsule(XXC).[Methods]The chromatographic conditions for the analysis of XXC solution were as follows:XSelect HSS T3 column;acetonitrile-0.1%phosphoric acid water was used as mo-bile phase,gradient elution;flow rate:1.0 mL/min;column temperature 30℃;The injection volume is 10μL.The quality of XXC samples produced by different manufacturers was evaluated by similarity evaluation and cluster analysis.[Results]In theHPLC-dad fingerprints of 15 batches of XXC,23 common peaks were identified and 9 peaks were identified,and the similarity was greater than 0.95.According to the re-sults of cluster analysis,15 batches of XXC samples could be divided into two categories,S2,S5,S6,S7 and S8 batches belonged to category Ⅰ,and the rest batches belonged to category Ⅱ.[Conclusions]In this study,a representative and universal identification method of Xxc HPLC-DAD fingerprint was established.The method has high precision,stability and repeatability,is simple and reliable,and provides a pow-erful reference for further improving the quality evaluation system of XXC.展开更多
The identification between chaotic systems and stochastic processes is not easy since they have numerous similarities. In this study, we propose a novel approach to distinguish between chaotic systems and stochastic p...The identification between chaotic systems and stochastic processes is not easy since they have numerous similarities. In this study, we propose a novel approach to distinguish between chaotic systems and stochastic processes based on the component reordering procedure and the visibility graph algorithm. It is found that time series and their reordered components will show diverse characteristics in the 'visibility domain'. For chaotic series, there are huge differences between the degree distribution obtained from the original series and that obtained from the corresponding reordered component. For correlated stochastic series, there are only small differences between the two degree distributions. For uncorrelated stochastic series, there are slight differences between them. Based on this discovery, the well-known Kullback Leible divergence is used to quantify the difference between the two degree distributions and to distinguish between chaotic systems, correlated and uncorrelated stochastic processes. Moreover, one chaotic map, three chaotic systems and three different stochastic processes are utilized to illustrate the feasibility and effectiveness of the proposed method. Numerical results show that the proposed method is not only effective to distinguish between chaotic systems, correlated and uncorrelated stochastic processes, but also easy to operate.展开更多
An improved covariance driven subspace identification method is presented to identify the weakly excited modes. In this method, the traditional Hankel matrix is replaced by a reformed one to enhance the identifiabilit...An improved covariance driven subspace identification method is presented to identify the weakly excited modes. In this method, the traditional Hankel matrix is replaced by a reformed one to enhance the identifiability of weak characteristics. The robustness of eigenparameter estimation to noise contamination is reinforced by the improved Hankel matrix, in combination with component energy index (CEI) which indicates the vibration intensity of signal components, an alternative stabilization diagram is adopted to effectively separate spurious and physical modes. Simulation of a vibration system of multiple-degree-of-freedom and experiment of a frame structure subject to wind excitation are presented to demonstrate the improvement of the proposed blind method. The performance of this blind method is assessed in terms of its capability in extracting the weak modes as well as the accuracy of estimated parameters. The results have shown that the proposed blind method gives a better estimation of the weak modes from response signals of small signal to noise ratio (SNR)and gives a reliable separation of spurious and physical estimates.展开更多
To avoid the decrease of system reliability due to insufficient component maintenance and the resource waste caused by excessive component maintenance,identifying the critical components of complex products is an effe...To avoid the decrease of system reliability due to insufficient component maintenance and the resource waste caused by excessive component maintenance,identifying the critical components of complex products is an effective way to improve the efficiency of maintenance activities.Existing studies on identifying critical components of complex products are mainly from two aspects i.e.,topological properties and functional properties,respectively.In this paper,we combine these two aspects to establish a hybrid intuitionistic fuzzy set to incorporate the different types of attribute values.Considering the mutual correlation between attributes,a combination of AHP(Analytic Hierarchy Process)and Improved Mahalanobis-Taguchi System(MTS)is used to determine the λ-Shapley fuzzy measures for attributes.Then,the λ-Shapley Choquet integral intuitionistic fuzzy TOPSIS(Technique for Order Preference by Similarity to an Ideal Solution)method is proposed for calculating the closeness degrees of components to generate their ranking order.Finally,a case study which is about the right gear of airbus 320 is taken as an example to verify the feasibility and effectiveness of this method.This novel methodology can effectively solve the critical components identification problem with different types of evaluation information and completely unknown weight information of attributes,which provides the implementation of protection measures for the system reliability of complex products.展开更多
The component-based business architecture integration of military information systems is a popu- lar research topic in the field of military operational research. Identifying enterprise-level business components is an...The component-based business architecture integration of military information systems is a popu- lar research topic in the field of military operational research. Identifying enterprise-level business components is an important issue in business architecture integration. Currently used methodologies for business component identification tend to focus on software-level business components, and ignore such enterprise concerns in business architectures as organizations and resources. Moreover, approaches to enterprise-level business component identi- fication have proven laborious. In this study, we propose a novel approach to enterprise-level business component identification by considering overall cohesion, coupling, granularity, maintainability, and reusability. We first define and formulate enterprise-level business components based on the component business model and the Department of Defense Architecture Framework (DoDAF) models. To quantify the indices of business components, we formulate a create, read, update, and delete (CRUD) matrix and use six metrics as criteria. We then formulate business com- ponent identification as a multi:objective optimization problem and solve it by a novel meta-heuristic optimization algorithm called the 'simulated annealing hybrid genetic algorithm (SHGA)'. Case studies showed that our approach is more practical and efficient for enterprise-level business component identification than prevalent approaches.展开更多
Identifying business components is the basis of component-based software engineering. Many approaches, including cluster analysis and concept analysis, have been proposed to identify components from business models. T...Identifying business components is the basis of component-based software engineering. Many approaches, including cluster analysis and concept analysis, have been proposed to identify components from business models. These approaches classify business elements into a set of components by analyzing their properties. However, most of them do not consider the difference in their properties for the business elements, which may decrease the ac- curacy of the identification results. Fhrthermore, component identification by partitioning business elements cannot reflect which features are responsible for the generation of certain results. This paper deals with a new approach for component identification from business models using fuzzy formal concept analysis. First, the membership between business elements and their properties is quantified and transformed into a fuzzy formal context, from which the concept lattice is built using a refined incremental algorithm. Then the components are selected from the concepts according to the concept dispersion and distance. Finally, the effectiveness and efficiency are validated by applying our approach in the real-life cases and experiments.展开更多
The research and development (R&D) process of Chinese medicine, with one notable feature, clinical application based, is significantly different from which of chemical and biological medicine, from laboratory resea...The research and development (R&D) process of Chinese medicine, with one notable feature, clinical application based, is significantly different from which of chemical and biological medicine, from laboratory research to clinics. Besides, compound prescription is another character. Therefore, according to different R&D theories between Chinese and Western medicine, we put forward a new strategy in drug design of Chinese medicine, which focuses on "combination- activity relationship (CAR)", taking prescription discovery, component identification and formula optimization as three key points to identify the drugs of high efficacy and low toxicity. The method of drug design of Chinese medicine includes: new prescription discovery based on clinical data and literature information, component identification based on computing and experimental research, as well as formula optimization based on system modeling. This paper puts forward the concept,research framework and techniques of drug design of Chinese medicine, which embodies the R&D model of Chinese medicine, hoping to support the drug design of Chinese medicine theoretically and technologically.展开更多
基金Supported by the Applied Basic Research Project in Sichuan(2018)National Science and Technology Support Program(2015BAC05B02)Innovative Research Projects of Graduate Students in Southwest Minzu University in 2017(CX2017SZ085)
文摘[Objectives] Volatile oil components of traditional drug use site " root and rhizome" of N. jatamansi and herb were identified and contrasted,which aimed to provide the basis for rationally using wild N. jatamansi resource. [Methods]Volatile oil components from different sites of N. jatamansi were identified and isolated by GC-MS. [Results] There were 56 kinds of volatile oil components from different sites of N. jatamansi,in which 39 components from herb of N. jatamansi,39 components from root and rhizome of N. jatamansi,and there were 22 common components. But 1 component in higher concentration had obvious difference. [Conclusions] The herb of N. jatamansi could not completely replace " root and rhizome" of N. jatamansi as the medicine,which was consistent with prior detection result of each physicochemical index from different sites of N. jatamansi. The research could provide the reference for making quality standard of N. jatamansi medicine and rational basis for its further research and development.
文摘[Objectives]To establish the HPLC-DAD fingerprint of Xueshuan Xinmaining Capsule(XXC).[Methods]The chromatographic conditions for the analysis of XXC solution were as follows:XSelect HSS T3 column;acetonitrile-0.1%phosphoric acid water was used as mo-bile phase,gradient elution;flow rate:1.0 mL/min;column temperature 30℃;The injection volume is 10μL.The quality of XXC samples produced by different manufacturers was evaluated by similarity evaluation and cluster analysis.[Results]In theHPLC-dad fingerprints of 15 batches of XXC,23 common peaks were identified and 9 peaks were identified,and the similarity was greater than 0.95.According to the re-sults of cluster analysis,15 batches of XXC samples could be divided into two categories,S2,S5,S6,S7 and S8 batches belonged to category Ⅰ,and the rest batches belonged to category Ⅱ.[Conclusions]In this study,a representative and universal identification method of Xxc HPLC-DAD fingerprint was established.The method has high precision,stability and repeatability,is simple and reliable,and provides a pow-erful reference for further improving the quality evaluation system of XXC.
基金Supported by the National Natural Science Foundation of China under Grant No U1530126
文摘The identification between chaotic systems and stochastic processes is not easy since they have numerous similarities. In this study, we propose a novel approach to distinguish between chaotic systems and stochastic processes based on the component reordering procedure and the visibility graph algorithm. It is found that time series and their reordered components will show diverse characteristics in the 'visibility domain'. For chaotic series, there are huge differences between the degree distribution obtained from the original series and that obtained from the corresponding reordered component. For correlated stochastic series, there are only small differences between the two degree distributions. For uncorrelated stochastic series, there are slight differences between them. Based on this discovery, the well-known Kullback Leible divergence is used to quantify the difference between the two degree distributions and to distinguish between chaotic systems, correlated and uncorrelated stochastic processes. Moreover, one chaotic map, three chaotic systems and three different stochastic processes are utilized to illustrate the feasibility and effectiveness of the proposed method. Numerical results show that the proposed method is not only effective to distinguish between chaotic systems, correlated and uncorrelated stochastic processes, but also easy to operate.
基金This project is supported by National Natural Science Foundation of China (No.10302019).
文摘An improved covariance driven subspace identification method is presented to identify the weakly excited modes. In this method, the traditional Hankel matrix is replaced by a reformed one to enhance the identifiability of weak characteristics. The robustness of eigenparameter estimation to noise contamination is reinforced by the improved Hankel matrix, in combination with component energy index (CEI) which indicates the vibration intensity of signal components, an alternative stabilization diagram is adopted to effectively separate spurious and physical modes. Simulation of a vibration system of multiple-degree-of-freedom and experiment of a frame structure subject to wind excitation are presented to demonstrate the improvement of the proposed blind method. The performance of this blind method is assessed in terms of its capability in extracting the weak modes as well as the accuracy of estimated parameters. The results have shown that the proposed blind method gives a better estimation of the weak modes from response signals of small signal to noise ratio (SNR)and gives a reliable separation of spurious and physical estimates.
基金supported by National Natural Science Foundation of China under Grant Nos.71471146,71501158 and 71871182General Program of Humanities and Social Sciences Research of Ministry of Education of China under Grant No.20XJA630003+1 种基金Fundamental Research Funds for the Central Universities under Grant No.3102020JC06Inno-vation Foundation for Doctor Dissertation of Northwestern Polytechnical University under Grant No.CX2021095.
文摘To avoid the decrease of system reliability due to insufficient component maintenance and the resource waste caused by excessive component maintenance,identifying the critical components of complex products is an effective way to improve the efficiency of maintenance activities.Existing studies on identifying critical components of complex products are mainly from two aspects i.e.,topological properties and functional properties,respectively.In this paper,we combine these two aspects to establish a hybrid intuitionistic fuzzy set to incorporate the different types of attribute values.Considering the mutual correlation between attributes,a combination of AHP(Analytic Hierarchy Process)and Improved Mahalanobis-Taguchi System(MTS)is used to determine the λ-Shapley fuzzy measures for attributes.Then,the λ-Shapley Choquet integral intuitionistic fuzzy TOPSIS(Technique for Order Preference by Similarity to an Ideal Solution)method is proposed for calculating the closeness degrees of components to generate their ranking order.Finally,a case study which is about the right gear of airbus 320 is taken as an example to verify the feasibility and effectiveness of this method.This novel methodology can effectively solve the critical components identification problem with different types of evaluation information and completely unknown weight information of attributes,which provides the implementation of protection measures for the system reliability of complex products.
基金Project supported by the National.Natural Science Foundation of China (No. 71571189)
文摘The component-based business architecture integration of military information systems is a popu- lar research topic in the field of military operational research. Identifying enterprise-level business components is an important issue in business architecture integration. Currently used methodologies for business component identification tend to focus on software-level business components, and ignore such enterprise concerns in business architectures as organizations and resources. Moreover, approaches to enterprise-level business component identi- fication have proven laborious. In this study, we propose a novel approach to enterprise-level business component identification by considering overall cohesion, coupling, granularity, maintainability, and reusability. We first define and formulate enterprise-level business components based on the component business model and the Department of Defense Architecture Framework (DoDAF) models. To quantify the indices of business components, we formulate a create, read, update, and delete (CRUD) matrix and use six metrics as criteria. We then formulate business com- ponent identification as a multi:objective optimization problem and solve it by a novel meta-heuristic optimization algorithm called the 'simulated annealing hybrid genetic algorithm (SHGA)'. Case studies showed that our approach is more practical and efficient for enterprise-level business component identification than prevalent approaches.
基金supported by the Fundamental Research Funds for the Central Universities,China
文摘Identifying business components is the basis of component-based software engineering. Many approaches, including cluster analysis and concept analysis, have been proposed to identify components from business models. These approaches classify business elements into a set of components by analyzing their properties. However, most of them do not consider the difference in their properties for the business elements, which may decrease the ac- curacy of the identification results. Fhrthermore, component identification by partitioning business elements cannot reflect which features are responsible for the generation of certain results. This paper deals with a new approach for component identification from business models using fuzzy formal concept analysis. First, the membership between business elements and their properties is quantified and transformed into a fuzzy formal context, from which the concept lattice is built using a refined incremental algorithm. Then the components are selected from the concepts according to the concept dispersion and distance. Finally, the effectiveness and efficiency are validated by applying our approach in the real-life cases and experiments.
文摘The research and development (R&D) process of Chinese medicine, with one notable feature, clinical application based, is significantly different from which of chemical and biological medicine, from laboratory research to clinics. Besides, compound prescription is another character. Therefore, according to different R&D theories between Chinese and Western medicine, we put forward a new strategy in drug design of Chinese medicine, which focuses on "combination- activity relationship (CAR)", taking prescription discovery, component identification and formula optimization as three key points to identify the drugs of high efficacy and low toxicity. The method of drug design of Chinese medicine includes: new prescription discovery based on clinical data and literature information, component identification based on computing and experimental research, as well as formula optimization based on system modeling. This paper puts forward the concept,research framework and techniques of drug design of Chinese medicine, which embodies the R&D model of Chinese medicine, hoping to support the drug design of Chinese medicine theoretically and technologically.