The theoretical research of cable-driven mechanisms is developed with its broad applications. The first prototype of cable-driven mechanisms is RoboCrane, which was developed by the National Institute of Standards and...The theoretical research of cable-driven mechanisms is developed with its broad applications. The first prototype of cable-driven mechanisms is RoboCrane, which was developed by the National Institute of Standards and Technology (NIST). Then many excellent properties were developed and they have a variety of applications such as aerospace, aircraft and automobile industries [1]. Example application for RoboCrane in the field of aircraft mainte- nance is equipped with a quick-change mechanism to remove the robot arm remotely.展开更多
Coffee is one of the world's favorite and most popular beverages,the third most popular beverage after water and tea.For many people,it is an indispensable habit before going to work and a socialization tool for t...Coffee is one of the world's favorite and most popular beverages,the third most popular beverage after water and tea.For many people,it is an indispensable habit before going to work and a socialization tool for the rest of the day.In general,the average consum ption varies from 2 to6 cups per day.What are the health implications?Given this consum ption,the benefits are actually greater than the risks.This is the conclusion of a careful study published in the New England Journal of Medicine(van Dam et al.,2020).展开更多
The concept of intraductal papillary neoplasm of the bile duct(IPNB)has gained recognition as a discrete entity[1,2],possessing many features including multiplicity[3,4],mucin production[3],slow progression[3,5],vario...The concept of intraductal papillary neoplasm of the bile duct(IPNB)has gained recognition as a discrete entity[1,2],possessing many features including multiplicity[3,4],mucin production[3],slow progression[3,5],various morphology[6,7],easy sloughing and seeding[8],and having unique risk factors[2,9-11].We have previously proposed a morphologic classification[6]and a progression model of IPNB[12].展开更多
Dear Editor,We have read with interest the article by Li et al[1].In the response to this article[1]which is a well thought out and written paper,I would like to draw attention to some critical points in this study an...Dear Editor,We have read with interest the article by Li et al[1].In the response to this article[1]which is a well thought out and written paper,I would like to draw attention to some critical points in this study and add some comments to the results and the conclusion of the study which authors have detected.In the Li et al’s[1]study,it is detected that,choroidal thickness is significantly negatively correlated with body mass index(BMI)and choroidal thickness is decreased in people with overweight or obesity.展开更多
Only when the foundation is strong will the state be safe and stable.THE concept that"the people are the foundation of a state"is the best expression of the people-centered philosophy of ancient China.Past C...Only when the foundation is strong will the state be safe and stable.THE concept that"the people are the foundation of a state"is the best expression of the people-centered philosophy of ancient China.Past Chinese sages and philosophers reached this conclusion in their study of state governance amid the rise and fall of dynasties over thousands of years.Based on the belief that the people's support of state power is vital for its success,this precept has inspired policies and practices aimed at nurturing,benefiting and enriching the people throughout Chinese history.展开更多
There are errors in Figure 1D1 on page 94.Specifically,RAB22A-induced autophagosomes were inadvertently marked in Figure 1D.We have revised Figure 1 to correct the errors.Of note,the errors do not impact the conclusio...There are errors in Figure 1D1 on page 94.Specifically,RAB22A-induced autophagosomes were inadvertently marked in Figure 1D.We have revised Figure 1 to correct the errors.Of note,the errors do not impact the conclusion of this article.We apologize for the errors and for any resulting confusion.展开更多
Abnormal subchondral bone remodeling leading to sclerosis is a main feature of osteoarthritis(OA), and osteomodulin(OMD), a proteoglycan involved in extracellular matrix mineralization, is associated with the scleroti...Abnormal subchondral bone remodeling leading to sclerosis is a main feature of osteoarthritis(OA), and osteomodulin(OMD), a proteoglycan involved in extracellular matrix mineralization, is associated with the sclerotic phenotype. However, the functions of OMD remain poorly understood, specifically in vivo. We used Omd knockout and overexpressing male mice and mutant zebrafish to study its roles in bone and cartilage metabolism and in the development of OA. The expression of Omd is deeply correlated with bone and cartilage microarchitectures affecting the bone volume and the onset of subchondral bone sclerosis and spontaneous cartilage lesions. Mechanistically, OMD binds to RANKL and inhibits osteoclastogenesis, thus controlling the balance of bone remodeling. In conclusion, OMD is a key factor in subchondral bone sclerosis associated with OA. It participates in bone and cartilage homeostasis by acting on the regulation of osteoclastogenesis. Targeting OMD may be a promising new and personalized approach for OA.展开更多
The authors examined the original data of their work and noticed misuse of images in fig.1 and fig.3(as shown below on the upper panels,red box).The correct images are shown on the lower panels(red box).The authors si...The authors examined the original data of their work and noticed misuse of images in fig.1 and fig.3(as shown below on the upper panels,red box).The correct images are shown on the lower panels(red box).The authors sincerely apologize for the mistake and confirm the change does not affect the scientific conclusion of the published work.展开更多
In the original version of this article,we published a figure showing a gap in the confidence intervals for body and tail due to data paucity for mid stages of moult progress.Here,we amended this problem adding data f...In the original version of this article,we published a figure showing a gap in the confidence intervals for body and tail due to data paucity for mid stages of moult progress.Here,we amended this problem adding data from the 2023 moulting season,during which we obtained 139 moult records from 98 individuals.The final sample size used for plotting these results are shown in the caption below.This amendment corroborates the conclusion already stated:body moult does not seem to be under physiological constraints,although primary moult appears to be tightly controlled to reduce aerodynamic losses.展开更多
Gravitational waves propagating at nanohertz frequencies?Do they exist?Yes.Four observational networks,from China,Australia,Europe-India,and USA,respectively,simultaneously answered on June 29,releasing results from t...Gravitational waves propagating at nanohertz frequencies?Do they exist?Yes.Four observational networks,from China,Australia,Europe-India,and USA,respectively,simultaneously answered on June 29,releasing results from their independent observations in the extremely low waveband of nanohertz.Consistent with each other,the results arrive at a common conclusion:our planet is immersed in a wavy spacetime ruffled by overlapping low-tone ripples.FAST,the Five-hundred-meter Aperture Spherical radio Telescope of China,is among the many giant telescopes that have played a key role in the search for this low-pitch voice.They are not the real detectors,though.展开更多
Super rice is an essendal part of China's rice production. Through survey on actual situation of 1568 households of rice growers in Heilongjiang, Hunan and Zhejiang provinces, this paper focused on influence of super...Super rice is an essendal part of China's rice production. Through survey on actual situation of 1568 households of rice growers in Heilongjiang, Hunan and Zhejiang provinces, this paper focused on influence of super rice development on increase of China's grain yield, influence on increase of rice growers' economic in- come, difference in production cost and profit between the North and the South, as well as profit percentage of super rice in production, processing, and sales. It obtained following results: rice price determines rice growers' income; expansion of super rice extension area plays a great role in increase of China's grain yield; by 2015 and 2020, keeping the yield of other crops not changed, merely the extension of super rice can increase grain for 5 million tons and 11 million tons separately; super rice significantly increases rice growers' economic income; for production cost of super rice, the South is higher than the North, and the profit ratio of cost is up to 35.54% on average; with respect of profit in production, processing, and sales, the ratio is 1:2:1.5; with the yield of other crops unchanged, every increase of 1% in area percentage of super rice to rice will additionally produce 1 million tons of grain for China, which is equivalent to saving the yield of 133 300 hm2 farmland and can additional feed 3.5 million people. In view of importance of super rice production, at the same time of strengthening research on super rice variety, it is required to accelerate expanding production area of super rice in suitable areas. Since the development of super rice can support China's ration demand of increasing population, China should make effort to realize "one yuan for one mu" financial subsidy for super rice of main grain production provinces and counties. Besides, China should establish special financial plan for extension of super rice.展开更多
The special issue deals with the Cretaceous-Tertiary deserts in southwestern China and relevant sedimentological problems about deserts. The study area is located between 101°10'- 107°00'E and 28°00'...The special issue deals with the Cretaceous-Tertiary deserts in southwestern China and relevant sedimentological problems about deserts. The study area is located between 101°10'- 107°00'E and 28°00'-30°40′ N. The ancient desert study is so little in China that there has not been a systematic report about it up to now. Based on the study in many ways on Cretaceous-Tertiary deserts in southwestern China, plentiful data have been obtained. Though it is still a bit rough, the study is a good beginning of the ancient desert study in China. The main ideas and conclusions are summarized as follows.展开更多
The authors regret that Fig.7b in our original article was incorrectly published,which is the same as Fig.6b due to an unintentional and random error.The correct Fig.7b is shown as follows(Reusability of the immobiliz...The authors regret that Fig.7b in our original article was incorrectly published,which is the same as Fig.6b due to an unintentional and random error.The correct Fig.7b is shown as follows(Reusability of the immobilized laccase).The change does not affect the results and conclusions.展开更多
Hsueh and O Brien (1971) proposed a model on coastal upwelling induced by alongshore current. Their model is two - dimensional .steady , f - plane , linear and homogeneous with constant depth , in which wind effect wa...Hsueh and O Brien (1971) proposed a model on coastal upwelling induced by alongshore current. Their model is two - dimensional .steady , f - plane , linear and homogeneous with constant depth , in which wind effect was not considered . In the present paper, we proposed a steady model on upwelling in a strait with alongshore boundary current and wind applied on the surface. The following conclusions have been drawn.1 . Alongshore boundary current contributes more to upwelling than wind near the right coast.2. Alongshore boundary current influence can reach to about 70 km away from the right coast.3. Upwelling in the left half of the strait is mainly produced by wind .4. Under certain conditions, the combined action of wind and alongshore boundary current can produce upwelling in the middle of the strait.展开更多
INTRODUCTION Machine learning(ML)techniques1 are becoming a major area of study in psychiatry,as ML possesses the theoretical capacity to draw conclusions based on a broad range of data once the system has been taught...INTRODUCTION Machine learning(ML)techniques1 are becoming a major area of study in psychiatry,as ML possesses the theoretical capacity to draw conclusions based on a broad range of data once the system has been taught through a process of trial and error.Specifically,and arguably most importantly,ML can do so more quickly and accurately than clinicians.2 Several studies have demonstrated accuracy through the use of ML in various populations and geographic locations,further perpetuating the perceived need to incorporate ML into ongoing studies.展开更多
INTRODUCTION Dissolution and precipitation of carbonates plays an important role in nature, such as in the chemistry of seawater, the sedimentation of carbonate at the seafloor, the geochemical evolution of freshwater...INTRODUCTION Dissolution and precipitation of carbonates plays an important role in nature, such as in the chemistry of seawater, the sedimentation of carbonate at the seafloor, the geochemical evolution of freshwater aquifers and last but not least, most spectacular, the evolution of karst landscapes. To provide a deeper understanding to all these processes knowledge is required展开更多
In the published paper1,the author's organization information on page 215 contained errors.The author information has been updated to correct the errors.The errors do not affect the conclusions of this article.We ...In the published paper1,the author's organization information on page 215 contained errors.The author information has been updated to correct the errors.The errors do not affect the conclusions of this article.We apologize for the errors and for any confusion they may have caused.展开更多
The short-term tests (STT) that have been usedsuccessfully to identify mutagens and potentialcarcinogens increasingly are being used to identifyantimutagens and potential anticarcinogens.Theconcept of activity profile...The short-term tests (STT) that have been usedsuccessfully to identify mutagens and potentialcarcinogens increasingly are being used to identifyantimutagens and potential anticarcinogens.Theconcept of activity profiles,already appliedsuccessfully to the display of mutagenicity展开更多
A relativistic extension for Blankenbecler-Goldberger approximation to the calculation of the electron capture processes in ion-atom collisions is developed.The results are compared with other methods and the relativi...A relativistic extension for Blankenbecler-Goldberger approximation to the calculation of the electron capture processes in ion-atom collisions is developed.The results are compared with other methods and the relativistic effects are discussed.Some new conclusions are obtained.展开更多
基金Supported by National Natural Science Foundation of China(Grant No.51575150)
文摘The theoretical research of cable-driven mechanisms is developed with its broad applications. The first prototype of cable-driven mechanisms is RoboCrane, which was developed by the National Institute of Standards and Technology (NIST). Then many excellent properties were developed and they have a variety of applications such as aerospace, aircraft and automobile industries [1]. Example application for RoboCrane in the field of aircraft mainte- nance is equipped with a quick-change mechanism to remove the robot arm remotely.
文摘Coffee is one of the world's favorite and most popular beverages,the third most popular beverage after water and tea.For many people,it is an indispensable habit before going to work and a socialization tool for the rest of the day.In general,the average consum ption varies from 2 to6 cups per day.What are the health implications?Given this consum ption,the benefits are actually greater than the risks.This is the conclusion of a careful study published in the New England Journal of Medicine(van Dam et al.,2020).
文摘The concept of intraductal papillary neoplasm of the bile duct(IPNB)has gained recognition as a discrete entity[1,2],possessing many features including multiplicity[3,4],mucin production[3],slow progression[3,5],various morphology[6,7],easy sloughing and seeding[8],and having unique risk factors[2,9-11].We have previously proposed a morphologic classification[6]and a progression model of IPNB[12].
文摘Dear Editor,We have read with interest the article by Li et al[1].In the response to this article[1]which is a well thought out and written paper,I would like to draw attention to some critical points in this study and add some comments to the results and the conclusion of the study which authors have detected.In the Li et al’s[1]study,it is detected that,choroidal thickness is significantly negatively correlated with body mass index(BMI)and choroidal thickness is decreased in people with overweight or obesity.
文摘Only when the foundation is strong will the state be safe and stable.THE concept that"the people are the foundation of a state"is the best expression of the people-centered philosophy of ancient China.Past Chinese sages and philosophers reached this conclusion in their study of state governance amid the rise and fall of dynasties over thousands of years.Based on the belief that the people's support of state power is vital for its success,this precept has inspired policies and practices aimed at nurturing,benefiting and enriching the people throughout Chinese history.
文摘There are errors in Figure 1D1 on page 94.Specifically,RAB22A-induced autophagosomes were inadvertently marked in Figure 1D.We have revised Figure 1 to correct the errors.Of note,the errors do not impact the conclusion of this article.We apologize for the errors and for any resulting confusion.
基金funded by the F.R.S.-FNRS for the “EOS: The Excellence of Science-Join-t-against-Osteoarthritis”, grant number 30480119by a research grant from the Osteoarthritis Foundation and by the University of Liege (Fonds Léon Fredericq and Fonds Speciaux à la Recherche)funded by Versus Arthritis senior fellowship 21937。
文摘Abnormal subchondral bone remodeling leading to sclerosis is a main feature of osteoarthritis(OA), and osteomodulin(OMD), a proteoglycan involved in extracellular matrix mineralization, is associated with the sclerotic phenotype. However, the functions of OMD remain poorly understood, specifically in vivo. We used Omd knockout and overexpressing male mice and mutant zebrafish to study its roles in bone and cartilage metabolism and in the development of OA. The expression of Omd is deeply correlated with bone and cartilage microarchitectures affecting the bone volume and the onset of subchondral bone sclerosis and spontaneous cartilage lesions. Mechanistically, OMD binds to RANKL and inhibits osteoclastogenesis, thus controlling the balance of bone remodeling. In conclusion, OMD is a key factor in subchondral bone sclerosis associated with OA. It participates in bone and cartilage homeostasis by acting on the regulation of osteoclastogenesis. Targeting OMD may be a promising new and personalized approach for OA.
文摘The authors examined the original data of their work and noticed misuse of images in fig.1 and fig.3(as shown below on the upper panels,red box).The correct images are shown on the lower panels(red box).The authors sincerely apologize for the mistake and confirm the change does not affect the scientific conclusion of the published work.
文摘In the original version of this article,we published a figure showing a gap in the confidence intervals for body and tail due to data paucity for mid stages of moult progress.Here,we amended this problem adding data from the 2023 moulting season,during which we obtained 139 moult records from 98 individuals.The final sample size used for plotting these results are shown in the caption below.This amendment corroborates the conclusion already stated:body moult does not seem to be under physiological constraints,although primary moult appears to be tightly controlled to reduce aerodynamic losses.
文摘Gravitational waves propagating at nanohertz frequencies?Do they exist?Yes.Four observational networks,from China,Australia,Europe-India,and USA,respectively,simultaneously answered on June 29,releasing results from their independent observations in the extremely low waveband of nanohertz.Consistent with each other,the results arrive at a common conclusion:our planet is immersed in a wavy spacetime ruffled by overlapping low-tone ripples.FAST,the Five-hundred-meter Aperture Spherical radio Telescope of China,is among the many giant telescopes that have played a key role in the search for this low-pitch voice.They are not the real detectors,though.
基金Supported by Super Rice Program for Agricultural Scientific&Technological Innovation Project of Chinese Academy of Agricultural SciencesSpecial Project of Public Welfare Industry of Ministry of Agriculture(201203029)Special Project for Construction of Modern Agricultural Industrial Technology System(CARS-01-09B)~~
文摘Super rice is an essendal part of China's rice production. Through survey on actual situation of 1568 households of rice growers in Heilongjiang, Hunan and Zhejiang provinces, this paper focused on influence of super rice development on increase of China's grain yield, influence on increase of rice growers' economic in- come, difference in production cost and profit between the North and the South, as well as profit percentage of super rice in production, processing, and sales. It obtained following results: rice price determines rice growers' income; expansion of super rice extension area plays a great role in increase of China's grain yield; by 2015 and 2020, keeping the yield of other crops not changed, merely the extension of super rice can increase grain for 5 million tons and 11 million tons separately; super rice significantly increases rice growers' economic income; for production cost of super rice, the South is higher than the North, and the profit ratio of cost is up to 35.54% on average; with respect of profit in production, processing, and sales, the ratio is 1:2:1.5; with the yield of other crops unchanged, every increase of 1% in area percentage of super rice to rice will additionally produce 1 million tons of grain for China, which is equivalent to saving the yield of 133 300 hm2 farmland and can additional feed 3.5 million people. In view of importance of super rice production, at the same time of strengthening research on super rice variety, it is required to accelerate expanding production area of super rice in suitable areas. Since the development of super rice can support China's ration demand of increasing population, China should make effort to realize "one yuan for one mu" financial subsidy for super rice of main grain production provinces and counties. Besides, China should establish special financial plan for extension of super rice.
文摘The special issue deals with the Cretaceous-Tertiary deserts in southwestern China and relevant sedimentological problems about deserts. The study area is located between 101°10'- 107°00'E and 28°00'-30°40′ N. The ancient desert study is so little in China that there has not been a systematic report about it up to now. Based on the study in many ways on Cretaceous-Tertiary deserts in southwestern China, plentiful data have been obtained. Though it is still a bit rough, the study is a good beginning of the ancient desert study in China. The main ideas and conclusions are summarized as follows.
文摘The authors regret that Fig.7b in our original article was incorrectly published,which is the same as Fig.6b due to an unintentional and random error.The correct Fig.7b is shown as follows(Reusability of the immobilized laccase).The change does not affect the results and conclusions.
文摘Hsueh and O Brien (1971) proposed a model on coastal upwelling induced by alongshore current. Their model is two - dimensional .steady , f - plane , linear and homogeneous with constant depth , in which wind effect was not considered . In the present paper, we proposed a steady model on upwelling in a strait with alongshore boundary current and wind applied on the surface. The following conclusions have been drawn.1 . Alongshore boundary current contributes more to upwelling than wind near the right coast.2. Alongshore boundary current influence can reach to about 70 km away from the right coast.3. Upwelling in the left half of the strait is mainly produced by wind .4. Under certain conditions, the combined action of wind and alongshore boundary current can produce upwelling in the middle of the strait.
基金JCL is supported by the Alfred Adler Scholarship.
文摘INTRODUCTION Machine learning(ML)techniques1 are becoming a major area of study in psychiatry,as ML possesses the theoretical capacity to draw conclusions based on a broad range of data once the system has been taught through a process of trial and error.Specifically,and arguably most importantly,ML can do so more quickly and accurately than clinicians.2 Several studies have demonstrated accuracy through the use of ML in various populations and geographic locations,further perpetuating the perceived need to incorporate ML into ongoing studies.
文摘INTRODUCTION Dissolution and precipitation of carbonates plays an important role in nature, such as in the chemistry of seawater, the sedimentation of carbonate at the seafloor, the geochemical evolution of freshwater aquifers and last but not least, most spectacular, the evolution of karst landscapes. To provide a deeper understanding to all these processes knowledge is required
文摘In the published paper1,the author's organization information on page 215 contained errors.The author information has been updated to correct the errors.The errors do not affect the conclusions of this article.We apologize for the errors and for any confusion they may have caused.
文摘The short-term tests (STT) that have been usedsuccessfully to identify mutagens and potentialcarcinogens increasingly are being used to identifyantimutagens and potential anticarcinogens.Theconcept of activity profiles,already appliedsuccessfully to the display of mutagenicity
基金Supported by Chinese Academy of Sciences(LWTZ-1298)by Chinese Research Center for Atomic and Molecular Data.
文摘A relativistic extension for Blankenbecler-Goldberger approximation to the calculation of the electron capture processes in ion-atom collisions is developed.The results are compared with other methods and the relativistic effects are discussed.Some new conclusions are obtained.