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Exploiting kinase polypharmacology for nerve regeneration
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作者 Hassan Al-Ali John L.Bixby Vance P.Lemmon 《Neural Regeneration Research》 SCIE CAS CSCD 2016年第1期71-72,共2页
The human central nervous system(CNS)has a markedly poor capacity for regenerating its axons following injury.This appears to be due to two main causes:1)a developmentally regulated decline in regenerative capacit... The human central nervous system(CNS)has a markedly poor capacity for regenerating its axons following injury.This appears to be due to two main causes:1)a developmentally regulated decline in regenerative capacity within mature CNS neurons,and 2)the presence of biological components that constitute barriers to axon regeneration(e.g.,growth-inhibitory molecules). 展开更多
关键词 regeneration alterations mature markedly constitute regenerative barriers phenotypic similarity inhibit
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