Contemporary approaches for imaging skeletal metastasis

The skeleton is a common site of cancer metastasis. Notably high incidences of bone lesions are found for breast, prostate, and renal carcinoma. Malignant bone tumors result in significant patient morbidity. Identification of these lesions is a critical step to accurately stratify patients, guide treatment course, monitor disease progression, and evaluate response to therapy. Diagnosis of cancer in the skeleton typically relies on indirect bone-targeted radiotracer uptake at sites of active bone remodeling. In this manuscript, we discuss established and emerging tools and techniques for detection of bone lesions, quantification of skeletal tumor burden, and current clinical challenges.

The interaction of history and modern thought in the creation of Iran’s architecture by investigating the approaches of past-oriented architecture

The relationship between tradition and modernity significantly influences society,culture,and architectural discourse.This philosophy offers a framework for exploring the impact of traditional architecture on contemporary Iranian architecture from different perspectives and approaches.Various viewpoints exist on whether historical architecture can be a defining characteristic of contemporary architectural discourse.Through an in-depth review of analysis-centred architectural literature,a unique method was chosen for analysing contemporary architecture and gaining insight into its creation.The main goal of this study is to establish a productive relationship between past-oriented architecture,innovative architectural concepts,and contemporary thought.This article examines three critical viewpoints,tradition as imitation,transmission,and transformation,alongside analysing their influential components on architectural form to gain insight into productively connecting with historical achievements and show that the role of history is to add new values to architecture-conscious needs that have changed during history.Ultimately,the challenge lies in finding a suitable path among diverse perspectives and reinterpretations and establishing a productive relationship with history and contemporary thought.

SPECIAL ISSUE： IMPORTANT ISSUES IN MARXIST PHILOSOPHICAL STUDIES IN CONTEMPORARY CHINA：The theory of question-oriented reflection and its contemporary significance

The critique of a premise and reflection on a question represent two different philosophical positions, and at the same time constitute two distinct routes by which contemporary philosophy has appeared on the scene. The critique of a premise, a discourse exercise aimed at the reconstruction of forms, is premised on a position of morphology. It obfuscates the real foundation of philosophy： all authentic philosophy originates from questions, and only the process of critical reflection on questions can provide an authentic context allowing philosophy＇s joumey into the depths. While philosophical discourse systems have always been distinguished by morphological construction, they have nontheless remained attempts at providing philosophical answers to questions posed by practice. Questions, as opposed to morphology, cannot but take precedence and be of a more fundamental nature. The theory of question-oriented reflection, as put forward by the Marxist revolution in philosophy, refers to the basic positions of the ＂theory of practice＂ and the ＂theory of the question.＂ It stongly holds that philosophy in essence is about the logic of questions and answers and its real point is ＂to change the world;＂ sound premises for philosophical forms can be arrived at only through critical rethinking of the philosophy arising from questions and the questions posed by philosophy, and only on such premises can philosophical forms be properly constructed.