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Effects of Continuous Precision Nursing Model on Knowledge, Attitudes, and Practices (KAP) Behavior and Cardiac Function in Patients after Percutaneous Coronary Angiography and Stent Implantation
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作者 Cuiying Han 《Journal of Clinical and Nursing Research》 2024年第3期1-6,共6页
Objective:To explore the impact of a continuous precision nursing model on patients’Knowledge,Attitudes,and Practices(KAP)and cardiac function during the nursing process of patients undergoing percutaneous coronary a... Objective:To explore the impact of a continuous precision nursing model on patients’Knowledge,Attitudes,and Practices(KAP)and cardiac function during the nursing process of patients undergoing percutaneous coronary angiography and stent implantation.Methods:Ninety patients who underwent percutaneous coronary angiography and stent implantation in our hospital from April 2022 to April 2023 were selected and randomly divided into the control group(45 cases),in which routine nursing support was carried out during the treatment process,and the observation group(45 cases),in which continuous precision nursing model was carried out during the treatment process.Comparisons were made between the two groups of patients on their KAP,cardiac function,and quality of life during recovery.Results:There was no difference in the left ventricular ejection fraction(LVEF),cardiac output(CO),and cardiac index(CI)levels before intervention.After the intervention,the levels of cardiac function in the observation group were higher than those of the control group(P<0.05).There was no difference in the Exercise of Self-Care Agency(ESCA)self-care ability scale scores before the intervention.After the intervention,the observation group had higher ESCA scores than the control group(P<0.05).Conclusion:Implementation of a continuous precision nursing model in the care of patients undergoing percutaneous coronary angiography and stent implantation improved the patient’s cardiac function,and KAP,and promoted recovery. 展开更多
关键词 continuous precision nursing model Percutaneous coronary angiography Stent implantation Knowledge attitudes and practices(KAP) Cardiac function
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Effect of continuous nursing combined with respiratory exercise nursing on pulmonary function of postoperative patients with lung cancer 被引量:4
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作者 Qiong-Xiang Qiu Wen-Juan Li +1 位作者 Xi-Miao Ma Xue-Hua Feng 《World Journal of Clinical Cases》 SCIE 2023年第6期1330-1340,共11页
BACKGROUND Lung cancer is a malignant tumor with high morbidity and mortality among cancers.Surgery is currently one of the primary methods of treating lung cancer.Although it can slow down the progression of the dise... BACKGROUND Lung cancer is a malignant tumor with high morbidity and mortality among cancers.Surgery is currently one of the primary methods of treating lung cancer.Although it can slow down the progression of the disease by removing the lesion,this invasive surgery inevitably damages the integrity of the patient’s chest.Moreover,the patient’s pulmonary function may have a low compensatory capacity after surgery,causing various respiratory diseases such as atelectasis,respiratory function decline,and even serious cardiovascular disease.All of these have great negative impacts on the surgical effect and the prognosis of patients.With the continuous exploration and development of nursing,continuous nursing and respiratory exercise nursing have been gradually applied in the nursing of patients after lung cancer surgery,and have achieved good nursing results.AIM To investigate the effect of continuous nursing combined with respiratory exercise nursing on the pulmonary function of postoperative patients with lung cancer.METHODS A total of 80 patients with lung cancer who underwent surgery in our hospital from January 2021 to December 2021 were selected as the study subjects.All subjects were randomly divided into the control group(n=40 cases)and the experimental group(n=40 cases).Patients with lung cancer in the control group were given conventional nursing after surgery,while the experimental group was given continuous nursing combined with respiratory exercise nursing based on conventional nursing.The recovery of pulmonary function and respiratory symptoms was observed before and after 3 mo of intervention in both groups.The pulmonary function parameters,blood gas analysis,MD Anderson Symptom Inventory-lung cancer module(MDASI-LC)scores,incidence of pulmonary complications,and Morisky compliance scores were compared between the two groups before and after 3 mo of intervention.RESULTS There was no significant difference in pulmonary function and blood gas analysis between the two groups before intervention(P>0.05).3 mo after the intervention,the pulmonary function parameters in the experimental group(SpO2,VC,MVV,FEV1,FEV1%pred,and FEV1/FVC)were higher than those in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in blood gas analysis between the two groups before intervention(P>0.05).PaO2 in the experimental group was significantly higher than that in the control group,and PaCO_(2) was significantly lower than that in the control group 3 mo after the intervention.The difference had statistical significance(P<0.05).3 mo after the intervention,the MDASI score of respiratory symptoms in the experimental group was significantly lower than that in the control group(P<0.05),and the incidence of pulmonary complications was lower than that in the control group(P<0.05).In addition,the treatment compliance and nursing satisfaction of patients in the experimental group were higher than those in the control group,and the differences were statistically significant(P<0.05).CONCLUSION Continuous nursing combined with respiratory exercise nursing can significantly accelerate the recovery of respiratory function in postoperative lung cancer patients,reduce the incidence of postoperative complications of lung cancer as well as improve the treatment compliance of patients. 展开更多
关键词 Postoperative lung cancer continuous nursing Respiratory exercise nursing Pulmonary function
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From Hölder Continuous Solutions of 3D Incompressible Navier-Stokes Equations to No-Finite Time Blowup on [ 0,∞ ]
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作者 Terry E. Moschandreou 《Advances in Pure Mathematics》 2024年第9期695-743,共49页
This article gives a general model using specific periodic special functions, that is, degenerate elliptic Weierstrass P functions composed with the LambertW function, whose presence in the governing equations through... This article gives a general model using specific periodic special functions, that is, degenerate elliptic Weierstrass P functions composed with the LambertW function, whose presence in the governing equations through the forcing terms simplify the periodic Navier Stokes equations (PNS) at the centers of arbitrary r balls of the 3-Torus. The continuity equation is satisfied together with spatially periodic boundary conditions. The yicomponent forcing terms consist of a function F as part of its expression that is arbitrarily small in an r ball where it is associated with a singular forcing expression both for inviscid and viscous cases. As a result, a significant simplification occurs with a v3(vifor all velocity components) only governing PDE resulting. The extension of three restricted subspaces in each of the principal directions in the Cartesian plane is shown as the Cartesian product ℋ=Jx,t×Jy,t×Jz,t. On each of these subspaces vi,i=1,2,3is continuous and there exists a linear independent subspace associated with the argument of the W function. Here the 3-Torus is built up from each compact segment of length 2R on each of the axes on the 3 principal directions x, y, and z. The form of the scaled velocities for non zero scaled δis related to the definition of the W function such that e−W(ξ)=W(ξ)ξwhere ξdepends on t and proportional to δ→0for infinite time t. The ratio Wξis equal to 1, making the limit δ→0finite and well defined. Considering r balls where the function F=(x−ai)2+(y−bi)2+(z−ci)2−ηset equal to −1e+rwhere r>0. is such that the forcing is singular at every distance r of centres of cubes each containing an r-ball. At the centre of the balls, the forcing is infinite. The main idea is that a system of singular initial value problems with infinite forcing is to be solved for where the velocities are shown to be locally Hölder continuous. It is proven that the limit of these singular problems shifts the finite time blowup time ti∗for first and higher derivatives to t=∞thereby indicating that there is no finite time blowup. Results in the literature can provide a systematic approach to study both large space and time behaviour for singular solutions to the Navier Stokes equations. Among the references, it has been shown that mathematical tools can be applied to study the asymptotic properties of solutions. 展开更多
关键词 Navier-Stokes Periodic Navier-Stokes Equations 3-Torus PERIODIC Ball Sphere Hölder continuous functions Uniqueness Angular Velocity Velocity in Terms of Vorticity
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Sub-Differential Characterizations of Non-Smooth Lower Semi-Continuous Pseudo-Convex Functions on Real Banach Spaces
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作者 Akachukwu Offia Ugochukwu Osisiogu +4 位作者 Theresa Efor Friday Oyakhire Monday Ekhator Friday Nkume Sunday Aloke 《Open Journal of Optimization》 2023年第3期99-108,共10页
In this paper, we characterize lower semi-continuous pseudo-convex functions f : X → R ∪ {+ ∞} on convex subset of real Banach spaces K  ⊂ X with respect to the pseudo-monotonicity of its Clarke-Rockafellar Su... In this paper, we characterize lower semi-continuous pseudo-convex functions f : X → R ∪ {+ ∞} on convex subset of real Banach spaces K  ⊂ X with respect to the pseudo-monotonicity of its Clarke-Rockafellar Sub-differential. We extend the results on the characterizations of non-smooth convex functions f : X → R ∪ {+ ∞} on convex subset of real Banach spaces K  ⊂ X with respect to the monotonicity of its sub-differentials to the lower semi-continuous pseudo-convex functions on real Banach spaces. 展开更多
关键词 Real Banach Spaces Pseudo-Convex functions Pseudo-Monotone Maps Sub-Differentials Lower Semi-continuous functions and Approximate Mean Value Inequality
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Effect of continuous nursing on treatment compliance and side effect management of coronary heart disease 被引量:1
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作者 Juan Wei Bai-Wen-Xian Li +2 位作者 Shao-Jie Han Hong-Jie Zhuang Wen-Hong Cao 《World Journal of Clinical Cases》 SCIE 2024年第19期3701-3707,共7页
BACKGROUND There are relatively few studies on continuing care of coronary heart disease(CHD),and its research value needs to be further clarified.AIM To investigate the effect of continuous nursing on treatment compl... BACKGROUND There are relatively few studies on continuing care of coronary heart disease(CHD),and its research value needs to be further clarified.AIM To investigate the effect of continuous nursing on treatment compliance and side effect management in patients with CHD.METHODS This is a retrospective study with patients from January 2021 to 2023.The study was divided into two groups with 30 participants in each group.Self-rating anxiety scale(SAS)and Self-rating depression scale(SDS)were used to assess patients'anxiety and depression,and medical coping questionnaire was used to assess patients'coping styles.The pelvic floor dysfunction questionnaire(PFDI-20)was used to assess the status of pelvic floor function,including bladder symptoms,intestinal symptoms,and pelvic symptoms.RESULTS SAS score decreased from 57.33±3.01before treatment to 41.33±3.42 after treatment,SDS score decreased from 50.40±1.45 to 39.47±1.57.The decrease of these two indexes was statistically significant(P<0.05).PFDI-20 scores decreased from the mean 16.83±1.72 before treatment to 10.47±1.3the mean after treatment,which was statistically significant(P<0.05).CONCLUSION The results of this study indicate that pioneering research in continuous care of CHD has a positive impact on improving patients'treatment compliance,reducing anxiety and depression levels,and improving coping styles and pelvic floor functional status. 展开更多
关键词 Coronary heart disease Continuing care Treatment compliance Anxiety and depression Coping style Pelvic floor function status Pioneering study
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Nonsingle-valley Continuous Solutions of p-order Feigenbaum's Functional Equation 被引量:2
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作者 张爱华 王立娟 宋威 《Northeastern Mathematical Journal》 CSCD 2003年第4期375-380,共6页
The author considers the Feigenbaum's functional equation fp(λx) = λf(x) for each p > 2. The existence of nonsingle-valley continuous solutions to this equation is discussed and a feasible method to construct... The author considers the Feigenbaum's functional equation fp(λx) = λf(x) for each p > 2. The existence of nonsingle-valley continuous solutions to this equation is discussed and a feasible method to construct such solutions is given. 展开更多
关键词 functional equation single-valley continuous solution nonsingle-valley continuous solution
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Dynamic Systems of Shifts in the Space of Piece-Wise Continuous Functions
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作者 Isaac Kwame Dontwi William Obeng-Denteh 《Advances in Pure Mathematics》 2012年第6期446-449,共4页
In this paper we embark on the study of Dynamic Systems of Shifts in the space of piece-wise continuous functions analogue to the known Bebutov system. We give a formal definition of a topological dynamic system in th... In this paper we embark on the study of Dynamic Systems of Shifts in the space of piece-wise continuous functions analogue to the known Bebutov system. We give a formal definition of a topological dynamic system in the space of piece-wise continuous functions and show, by way of an example, stability in the sense of Poisson discontinuous function. We prove that a fixed discontinuous function, f, is discontinuous for all its shifts, whereas the trajectory of discontinuous function is not a compact set. 展开更多
关键词 Dynamic System SHIFTS PIECEWISE continuous functions Compact Sets POISSON DIScontinuous function
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A Note on Discontinuous Functions with Continuous Second Iterate
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作者 Pingping Zhang Xiaobing Gong 《Journal of Applied Mathematics and Physics》 2015年第6期691-696,共6页
This paper investigates four classes of functions with a single discontinuous point. We give the sufficient and necessary conditions under which the second order iterates are continuous functions. Furthermore, the suf... This paper investigates four classes of functions with a single discontinuous point. We give the sufficient and necessary conditions under which the second order iterates are continuous functions. Furthermore, the sufficient conditions for the continuity of the even order iterates with finitely many discontinuous points are obtained. 展开更多
关键词 ITERATION DIScontinuous POINT continuous function
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Inverse Limit of Spaces of Upper Semicontinuous Functions
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作者 张德学 《Northeastern Mathematical Journal》 CSCD 2001年第1期49-52,共4页
Given a compact Hausdorff space X, U(X) denotes the compact Hausdorff space of all the upper semicontinuous functions from X to the unit interval with the dual lim inf topology. Then U is an endofunctor o... Given a compact Hausdorff space X, U(X) denotes the compact Hausdorff space of all the upper semicontinuous functions from X to the unit interval with the dual lim inf topology. Then U is an endofunctor on compact Hausdorff space. It is proved in this note that this functor preserves inverse limits. 展开更多
关键词 upper semicontinuous function continuous lattice lim inf convergence inverse limit
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CONSTRUCTION OF SOME KIESSWETTER-LIKE FUNCTIONS-THE CONTINUOUS BUT NON-DIFFERENT-IABLE FUNCTION DEFINED BY QUINARY DECIMAL 被引量:1
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作者 TieYong YangGuangjun 《Analysis in Theory and Applications》 2004年第1期58-68,共11页
In this paper, we construct some continuous but non-differentiable functions defined by quinary dec-imal, that are Kiesswetter-like functions. We discuss their properties, then investigate the Hausdorff dimensions of ... In this paper, we construct some continuous but non-differentiable functions defined by quinary dec-imal, that are Kiesswetter-like functions. We discuss their properties, then investigate the Hausdorff dimensions of graphs of these functions and give a detailed proof. 展开更多
关键词 Kiesswetter-like functions continuous but non-differentiable quinary decimal iterated function system inequality Hausdorff dimension
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Techniques of Discrete Function Transfers into Continuous Function in Practice 被引量:1
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作者 Ming-Jong Lin 《Engineering(科研)》 2018年第10期680-687,共8页
One confusing question over a long period of time is how transfer the discrete function transfers into continuous function. Recently the issue has been resolved but some details of the transformation process will be i... One confusing question over a long period of time is how transfer the discrete function transfers into continuous function. Recently the issue has been resolved but some details of the transformation process will be introduced in the paper. The correlation coefficients of 100,000 values are established from the two groups of data with the range between -1 and 1, creating a histogram from these correlation coefficient values known as “the probability mass function.” The coefficient values are brought into the discrete distribution function, so that transfers into the discrete cumulative function, next converted into a continuous cumulative function, next which is differentiated to get the density function, so that it is easy to being research analysis. A model will be established during the process of the conversion what the medium is “the least squares algorithm.” Finally, when the integral of the area within the range of the density function equals to 1, this implies that the transformation complete succeeds from the discrete function to the continuous function. 展开更多
关键词 PROBABILITY MASS function DISCRETE CUMULATIVE function continuous CUMULATIVE function PROBABILITY Density function The Least SQUARES Algorithm
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Do Continuous Flow LVADS Improve Diastolic Dysfunction? 被引量:1
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作者 Nandini Nair Sudhir Thotakura Enrique Gongora 《Open Journal of Organ Transplant Surgery》 2014年第3期23-28,共6页
Background: Ventricular assist devices are now used as a bridge to recovery/decision/transplant or as destination therapy in end-stage heart failure. Continued improvements in technology and pump design have made impl... Background: Ventricular assist devices are now used as a bridge to recovery/decision/transplant or as destination therapy in end-stage heart failure. Continued improvements in technology and pump design have made implantation an easier process with reduced operative risks and pump-related adverse events. Considering the beneficial effects of these devices in the clinical setting, it seemed logical to address the long-term effect of the continuous flow pumps on diastolic dysfunction. Methods: This study addresses the effect of HeartMate IITM(HMII) support for 284+/-97 days on echocardiographic parameters of diastolic function. Data from fifteen patients was retrospectively studied status post left ventricular assist device (LVAD) implantation. The data at approximately 1-year post implantation was compared with that obtained prior to implantation. Statistical analyses were performed using the Microsoft Excel Program/MSExcel Stats. Echocardiographic measurements were carried out in accordance with the American Society of Echocardiography guidelines. Results: Of all the echocardiographic parameters assessed only E/Ea and calculated left atrial pressure (LAP) showed a statistically significant decrease. Two parameters that showed a trend towards significance are Ea (septal) and global functional index (p = 0.05). Conclusions: Continuous Flow LVAD support appears to improve diastolic dysfunction. This study has limitations in that we used a single type of continuous flow device (HeartMate IITM) and was conducted as a retrospective analysis. Further studies with larger populations and longer support are required to validate this finding. 展开更多
关键词 continuous Flow Device DIASTOLIC function HeartMate IITM LEFT VENTRICULAR Assist Devise
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On the Method of Multiplier-enlargement and Approximation of Unbounded Continuous Functions 被引量:1
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作者 郑成德 王仁宏 《Northeastern Mathematical Journal》 CSCD 2001年第2期231-235,共5页
By combining the classical appropriate functions “1, x, x 2” with the method of multiplier enlargement, this paper establishes a theorem to approximate any unbounded continuous functions with modified positive... By combining the classical appropriate functions “1, x, x 2” with the method of multiplier enlargement, this paper establishes a theorem to approximate any unbounded continuous functions with modified positive linear operators. As an example, Hermite Fejér interpolation polynomial operators are analysed and studied, and a general conclusion is obtained. 展开更多
关键词 positive linear operator approximation of unbounded continuous function method of multiplier enlargement Hermite Fejér interpolation polynomial operator
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Cylindrical Guided Wave Signals for Underground Pipe Inspection using Different Continuous Wavelet Mother Functions 被引量:1
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作者 Rais Ahmad Tribikram Kundu 《Journal of Civil Engineering and Architecture》 2011年第12期1103-1110,共8页
Over the past decade, wavelets provided a powerful and flexible set of tools for handling fundamental problems in science and engineering. Wavelet analyses are being used for solving problems in different engineering ... Over the past decade, wavelets provided a powerful and flexible set of tools for handling fundamental problems in science and engineering. Wavelet analyses are being used for solving problems in different engineering areas like audio de-noising, signal compression, object detection, image decomposition, speech recognition etc. Wavelet analysis employs orthonormal as well as non-orthonornal functions. This research investigates the effectiveness of wavelet analysis in detecting defects in underground steel pipe networks. Continuous Wavelet Transforms (CWT) has been performed on the received signals of cylindrical guided waves. Cylindrical Guided waves are generated and propagated through the pipe wall boundaries in a pitch-catch system. Piezo-electric transducers are used to generate as well as receive guided waves. Several mother wavelet functions such as Daubechies, Symlet, Coiflet and Meyer have been used for the Continuous Wavelet Transform to investigate the most suitable function for defect detection. This research also investigates the effect of surrounding soil on wavelet transforms for different mother wavelet functions. 展开更多
关键词 Wavelet analysis guided waves mother wavelet functions continuous wavelet transform.
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Structure and Material Design of High Performance Functional Refractories for High-speed Continuous Casting
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作者 LI Hongxia,LIU Guoqi,YANG Wengang,YU Jianbin,MA Tianfei,QIAN Fan State Key Laboratory of Advanced Refractories,Sinosteel Luoyang Institute of Refractories Research Co. ,Ltd. ,Luoyang 471039,China 《China's Refractories》 CAS 2012年第1期1-5,共5页
Functional refractories, including submerged entry ,mzzle (SEN) , ladle shroud and monolithic stopper, are ,he key refractories for continuous casting. Drh,en by the demand (f high-speed continuous casting, traditi... Functional refractories, including submerged entry ,mzzle (SEN) , ladle shroud and monolithic stopper, are ,he key refractories for continuous casting. Drh,en by the demand (f high-speed continuous casting, traditional (unetional refractories ji,il to meet the needs of long span life, and high perfomance .[imctional refractories for continuous casting are hwreasingly required. Through structure and material de.sign, the performance of functional refiactories is significant5 improved. In this paper, some research adt,ances on functional refractories for continuous casting wetr mentiotted. Through numerical qmdeling and hot simulation, the service life of non-pretreating ladle shroud u,as increased front 8 h to more 'ban 12 h. Thraugh the water modeling, the flow patterns in the mold wetr significantly improved attd through hot simulation and material design, the sen;ice liJb and eliability oJ SEN were also significantly improved. 展开更多
关键词 functionAL REFRACTORIES continuous casting hotsimulation
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Continuous Piecewise Linear Approximation of BV Function
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作者 Hua Yi Tao Yu +1 位作者 Zhiquan Chen Jingwen Zhu 《Applied Mathematics》 2014年第4期667-671,共5页
Nonlinear approximation is widely used in signal processing. Real-life signals can be modeled as functions of bounded variation. Thus the variable knot of approximating function could be self- adaptively chosen by bal... Nonlinear approximation is widely used in signal processing. Real-life signals can be modeled as functions of bounded variation. Thus the variable knot of approximating function could be self- adaptively chosen by balancing the total variation of the target function. In this paper, we adopt continuous piecewise linear approximation instead of the existing piecewise constants approximation. The results of experiments show that this new method is superior to the old one. 展开更多
关键词 Nonlinear Approximation BOUNDED Variation continuous PIECEWISE Linear BASIS function PIECEWISE Constant BASIS function Compression DENOISING
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On Continuous Programming with Support Functions
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作者 Iqbal Husain Santosh K. Shrivastav Abdul Raoof Shah 《Applied Mathematics》 2013年第10期1441-1449,共9页
A second-order Mond-Weir type dual problem is formulated for a class of continuous programming problems in which both objective and constraint functions contain support functions;hence it is nondifferentiable. Under s... A second-order Mond-Weir type dual problem is formulated for a class of continuous programming problems in which both objective and constraint functions contain support functions;hence it is nondifferentiable. Under second-order strict pseudoinvexity, second-order pseudoinvexity and second-order quasi-invexity assumptions on functionals, weak, strong, strict converse and converse duality theorems are established for this pair of dual continuous programming problems. Special cases are deduced and a pair of dual continuous problems with natural boundary values is constructed. A close relationship between the duality results of our problems and those of the corresponding (static) nonlinear programming problem with support functions is briefly outlined. 展开更多
关键词 continuous PROGRAMMING SECOND-ORDER Generalized INVEXITY SECOND-ORDER DUALITY Nonlinear PROGRAMMING Support functions Natural BOUNDARY VALUES
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Second-Order Duality for Continuous Programming Containing Support Functions
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作者 Iqbal Husain Mashoob Masoodi 《Applied Mathematics》 2010年第6期534-541,共8页
A second-order dual problem is formulated for a class of continuous programming problem in which both objective and constrained functions contain support functions, hence it is nondifferentiable. Under second-order in... A second-order dual problem is formulated for a class of continuous programming problem in which both objective and constrained functions contain support functions, hence it is nondifferentiable. Under second-order invexity and second-order pseudoinvexity, weak, strong and converse duality theorems are established for this pair of dual problems. Special cases are deduced and a pair of dual continuous problems with natural boundary values is constructed. A close relationship between duality results of our problems and those of the corresponding (static) nonlinear programming problem with support functions is briefly outlined. 展开更多
关键词 continuous PROGRAMMING SECOND-ORDER INVEXITY SECOND-ORDER PSEUDOINVEXITY SECOND-ORDER DUALITY Nonlinear PROGRAMMING Support functions Natural Boundary VALUES
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Regularity of Continuous Linear Operators on Banach Function Spaces
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作者 JIANGNian-shengt ChenZi-li 《Chinese Quarterly Journal of Mathematics》 CSCD 2004年第1期51-56,共6页
In this paper we present some characterizations of Banach function spaces on which every continuous linear operator is regular.
关键词 Banach function space continuous linear operator REGULAR
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Efficacy of Ulinastatin Combined with Continuous Renal Replacement Therapy in the Treatment of Sepsis Acute Kidney Injury and Its Effects on Systemic Inflammation, Immune Function and miRAN Expression
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作者 Yudong Guan Lin Wu Yang Xiao 《Open Journal of Nephrology》 CAS 2022年第3期323-331,共9页
Objective: To research the effectiveness of ulinastatin in combination with continuous renal replacement therapy in treating sepsis acute kidney injury and its effect on systemic inflammation, immune function and miRA... Objective: To research the effectiveness of ulinastatin in combination with continuous renal replacement therapy in treating sepsis acute kidney injury and its effect on systemic inflammation, immune function and miRAN expression. Methods: The 84 patients who were diagnosed with sepsis complicated by acute kidney injury in our hospital between May 2020 and June 2022 were chosen and randomly assigned to the study group (n = 42) and the control group (n = 42). Ulinastatin in combination with continuous renal replacement therapy was administered to the study group, whereas the control group was administered with continuous renal replacement therapy alone. Both groups’ clinical effects were observed. The levels of blood urea nitrogen (BUN), serum creatinine (SCr), tumor necrosis factor-α (TNF-α), high sensitivity Creactive protein (hs-CRP), vascular cell adhesion molecule-1 (VCAM-1), IgG, IgA, IgM, expression levels of miR-233 and miR-10a were compared among both the groups, pre-, and post-treatment. Results: The study group’s overall effectiveness rate was higher that is 95.24%, in comparison to the control group’s 78.57%, and this difference was statistically significant (P α, hs-CRP, VCAM-1, and miR-233 and miR-10a expression levels in both the study and control groups were decreased, however, the study group had reduced levels in comparison to the control group, with statistically significant differences (P P Conclusion: Ulinastatin in combination with continuous renal replacement therapy for treating sepsis acute kidney injury exhibits a positive effect and can significantly improve the systemic inflammation and immune function in patients. 展开更多
关键词 ULINASTATIN Immune function continuous Renal Replacement Therapy Systemic Inflammation Sepsis Acute Kidney Injury miRAN
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