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Modeling optimal oil production paths under risk service contracts 被引量:1
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作者 Luo Dongkun Zhao Xu 《Petroleum Science》 SCIE CAS CSCD 2013年第4期596-602,共7页
Due to the rigorous fiscal terms and huge potential risk of risk service contracts,optimizing oil production paths is one of the main challenges in designing oilfield development plans.In this paper,an oil production ... Due to the rigorous fiscal terms and huge potential risk of risk service contracts,optimizing oil production paths is one of the main challenges in designing oilfield development plans.In this paper,an oil production path optimization model is developed to maximize economic benefits within constraints of technology factors and oil contracts.This analysis describes the effects of risk service contract terms on parameters of inputs and outputs and quantifies the relationships between production and production time,revenues,investment and costs.An oil service development and production project is illustrated in which the optimal production path under its own geological conditions and contract terms is calculated.The influences of oil price,service fees per barrel and operating costs on the optimal production have been examined by sensitivity analysis.The results show that the oil price has the largest impact on the optimal production,which is negatively related to oil price and positively related to service fees per barrel and operating costs. 展开更多
关键词 Risk service contract optimal production path nonlinear programming service fees per barrel sensitivity analysis
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Viruses and autism: A Bi-mutual cause and effect
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作者 Mohammed Al-Beltagi Nermin Kamal Saeed +3 位作者 Reem Elbeltagi Adel Salah Bediwy Syed A Saboor Aftab Rawan Alhawamdeh 《World Journal of Virology》 2023年第3期172-192,共21页
Autism spectrum disorder(ASD)is a group of heterogeneous,multi-factorial,neurodevelopmental disorders resulting from genetic and environmental factors interplay.Infection is a significant trigger of autism,especially ... Autism spectrum disorder(ASD)is a group of heterogeneous,multi-factorial,neurodevelopmental disorders resulting from genetic and environmental factors interplay.Infection is a significant trigger of autism,especially during the critical developmental period.There is a strong interplay between the viral infection as a trigger and a result of ASD.We aim to highlight the mutual relationship between autism and viruses.We performed a thorough literature review and included 158 research in this review.Most of the literature agreed on the possible effects of the viral infection during the critical period of development on the risk of developing autism,especially for specific viral infections such as Rubella,Cytomegalovirus,Herpes Simplex virus,Varicella Zoster Virus,Influenza virus,Zika virus,and severe acute respiratory syndrome coronavirus 2.Viral infection directly infects the brain,triggers immune activation,induces epigenetic changes,and raises the risks of having a child with autism.At the same time,there is some evidence of increased risk of infection,including viral infections in children with autism,due to lots of factors.There is an increased risk of developing autism with a specific viral infection during the early developmental period and an increased risk of viral infections in children with autism.In addition,children with autism are at increased risk of infection,including viruses.Every effort should be made to prevent maternal and early-life infections and reduce the risk of autism.Immune modulation of children with autism should be considered to reduce the risk of infection. 展开更多
关键词 AUTISM Children Rubella Cytomegalovirus Herpes simplex virus Influenza virus Zika virus SARS-CoV-2 COVID-19 Viral infection Core Tip:There is a mutual relationship between viral infections and autism.There is an increased risk of developing autism when contracting a viral infection during pregnancy or early postnatal life during the critical period of brain development.At the same time children with autism have many co-morbidities that expose them to more risk of contracting infections including viruses.Therefore every effort should be made to prevent infections especially during this critical period of neurodevelopment.Parents should also be educated about the importance of vaccination and immune modulation in children with autism to avoid further infections.
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