In this paper, we conduct research on primary core factors of influencing college students' entrepreneurial success rate under the perspectives of the law and team management perspectives. College students' entrepre...In this paper, we conduct research on primary core factors of influencing college students' entrepreneurial success rate under the perspectives of the law and team management perspectives. College students' entrepreneurship education is cultivating he students innovative spirit and creative ability as the basic value tendency, in order to cultivate creative talents as the main goal of education, it is an extension of the quality-oriented education, is the comprehensive development of students' qualities of wisdom education is the all-round development of students' personality education 'is pay more attention to the body of the human spirit, the humanist education. Carrying out entrepreneurship education, the reform and development of higher education to improve the quality of talent training levels promote national independent innovation and entrepreneurship has important significance. Our research proposes the novel perspective on the issues that is meaningful.展开更多
Nitrate,an oxidized product of NO x preserved in the polar ice cores,has often been used to estimate past changes of the atmospheric nitrogen cycle.A 102.65 m ice core drilled at DT-401(79°01'S,77°00'...Nitrate,an oxidized product of NO x preserved in the polar ice cores,has often been used to estimate past changes of the atmospheric nitrogen cycle.A 102.65 m ice core drilled at DT-401(79°01'S,77°00'E) in 1999 provides an opportunity to investigate the possible influencing factors for the nitrate budget in the eastern Antarctica.We studied the relationship between the δ18O(representing the temperature),accumulation rate,volcanic deposition and the astronomical factors(such as the solar activities,supernovae,etc.),and the nitrate variation along the whole duration(2680-year) of the ice core.Prominent impacts of the accumulation rate acting on the nitrate flux rather than the concentration were detected.However,no significant correlation was found between the δ18O and the nitrate deposition characteristics(concentration and the flux variations).Volcanic deposition can significantly affect the deposition of nitrate with a decreasing trend accompanied by the nss-SO42(volcanic signal) peak values.Impacts of the solar activities on the nitrate deposition can be detected at this site,and three prominent periodicities(16.6,24.0 and 102.0 yr) were found for the nitrate concentration variations.Six climatic events(Dalton Minimum,Maunder Minimum,Sporer Minimum,Wolf Minimum,Oort Minimum and Medieval Maximum) during the past 1150 years were observed with lower nitrate values for the foregoing five events and higher value for the last one.展开更多
The problem of steady rotation of a composite sphere located at the centre of a spherical container has been investigated. A composite particle referred to in this paper is a spherical solid core covered with a permea...The problem of steady rotation of a composite sphere located at the centre of a spherical container has been investigated. A composite particle referred to in this paper is a spherical solid core covered with a permeable spherical shell. The Brinkman's model for the flow inside the compos- ite sphere and the Stokes equation for the flow in the spheri- cal container were used to study the motion. The torque ex- perienced by the porous spherical particle in the presence of cavity is obtained. The wall correction factor is calculated. In the limiting cases, the analytical solution describing the torque for a porous sphere and for a solid sphere in an un- bounded medium are obtained from the present analysis.展开更多
In this paper, we investigate the effect and the possible mechanism of high glucose levels on the calcification of human aortic smooth muscle cells (HASMCs). HASMCs were divided into four groups: normal glucose gro...In this paper, we investigate the effect and the possible mechanism of high glucose levels on the calcification of human aortic smooth muscle cells (HASMCs). HASMCs were divided into four groups: normal glucose group (NG), osmolality control group (OC), high glucose group (HG, HASMCs culture medium containing 30 mmol/L glucose), and high glucose plus recombinant human Noggin protein (bone morphogenetic protein-2 (BMP-2) antagonist) group (HN). The mRNA levels and the protein expressions of BMP-2 and core binding factor alpha-1 (Cbfa-1) were measured by real-time quantitative polymerase chain reaction (PCR) and Western blot. After induced by 10 mmol/L β-glycerol phosphoric acid, cells were had'vested for assessments of alkaline phosphatase (ALP) activities at Days 1,2, and 3, and intracellular calcium contents at Days 7 and 14, respectively. High glucose levels increased the mRNA levels and the protein expressions of BMP-2 and Cbfa-1 (P〈0.05). The expression of Cbfa-1 was partially blocked by Noggin protein (P〈0.05), while BMP-2 was not (P〉0.05). After being induced by β-glycerol phosphoric acid, high glucose levels increased the ALP activity [(48.63±1.03) vs. (41.42±2.28) U/mg protein, Day 3; P〈0.05] and the intracellular calcium content [(2.76±0.09) vs. (1.75±0.07) μmol/mg protein, Day 14; P〈0.05] in a time-dependent manner when compared with the NG group, while the ALP activity could not be blocked by Noggin protein [(48.63±1.03) vs. (47.37±0.97) U/mg protein, Day 3; P〉0.05]. These results show that high glucose levels can evoke the calcification of HASMCs by inducing osteoblastic trans-differentiation and intracellular calcium deposition via the BMP-2/Cbfa-1 pathway, which can be partially blocked by Noggin protein.展开更多
文摘In this paper, we conduct research on primary core factors of influencing college students' entrepreneurial success rate under the perspectives of the law and team management perspectives. College students' entrepreneurship education is cultivating he students innovative spirit and creative ability as the basic value tendency, in order to cultivate creative talents as the main goal of education, it is an extension of the quality-oriented education, is the comprehensive development of students' qualities of wisdom education is the all-round development of students' personality education 'is pay more attention to the body of the human spirit, the humanist education. Carrying out entrepreneurship education, the reform and development of higher education to improve the quality of talent training levels promote national independent innovation and entrepreneurship has important significance. Our research proposes the novel perspective on the issues that is meaningful.
基金supported by the Foundation for Excellent Youth Scholars of CAREERI,CASthe National Natural Science Foundation of China(Grant Nos.40776002,40825017,41171052)+2 种基金the Hundred Talent Project of Chinese Academy of Sciencesthe Polar Scientific Explore Organizing Committee Foundation (Grant Nos.20080202&0852H71001)State Oceanic Administration of People's Republic of China Project on Climate in Polar Regions(Grant Nos.CHINARE2012-04-04 and CHINARE2012-02-02)
文摘Nitrate,an oxidized product of NO x preserved in the polar ice cores,has often been used to estimate past changes of the atmospheric nitrogen cycle.A 102.65 m ice core drilled at DT-401(79°01'S,77°00'E) in 1999 provides an opportunity to investigate the possible influencing factors for the nitrate budget in the eastern Antarctica.We studied the relationship between the δ18O(representing the temperature),accumulation rate,volcanic deposition and the astronomical factors(such as the solar activities,supernovae,etc.),and the nitrate variation along the whole duration(2680-year) of the ice core.Prominent impacts of the accumulation rate acting on the nitrate flux rather than the concentration were detected.However,no significant correlation was found between the δ18O and the nitrate deposition characteristics(concentration and the flux variations).Volcanic deposition can significantly affect the deposition of nitrate with a decreasing trend accompanied by the nss-SO42(volcanic signal) peak values.Impacts of the solar activities on the nitrate deposition can be detected at this site,and three prominent periodicities(16.6,24.0 and 102.0 yr) were found for the nitrate concentration variations.Six climatic events(Dalton Minimum,Maunder Minimum,Sporer Minimum,Wolf Minimum,Oort Minimum and Medieval Maximum) during the past 1150 years were observed with lower nitrate values for the foregoing five events and higher value for the last one.
文摘The problem of steady rotation of a composite sphere located at the centre of a spherical container has been investigated. A composite particle referred to in this paper is a spherical solid core covered with a permeable spherical shell. The Brinkman's model for the flow inside the compos- ite sphere and the Stokes equation for the flow in the spheri- cal container were used to study the motion. The torque ex- perienced by the porous spherical particle in the presence of cavity is obtained. The wall correction factor is calculated. In the limiting cases, the analytical solution describing the torque for a porous sphere and for a solid sphere in an un- bounded medium are obtained from the present analysis.
文摘In this paper, we investigate the effect and the possible mechanism of high glucose levels on the calcification of human aortic smooth muscle cells (HASMCs). HASMCs were divided into four groups: normal glucose group (NG), osmolality control group (OC), high glucose group (HG, HASMCs culture medium containing 30 mmol/L glucose), and high glucose plus recombinant human Noggin protein (bone morphogenetic protein-2 (BMP-2) antagonist) group (HN). The mRNA levels and the protein expressions of BMP-2 and core binding factor alpha-1 (Cbfa-1) were measured by real-time quantitative polymerase chain reaction (PCR) and Western blot. After induced by 10 mmol/L β-glycerol phosphoric acid, cells were had'vested for assessments of alkaline phosphatase (ALP) activities at Days 1,2, and 3, and intracellular calcium contents at Days 7 and 14, respectively. High glucose levels increased the mRNA levels and the protein expressions of BMP-2 and Cbfa-1 (P〈0.05). The expression of Cbfa-1 was partially blocked by Noggin protein (P〈0.05), while BMP-2 was not (P〉0.05). After being induced by β-glycerol phosphoric acid, high glucose levels increased the ALP activity [(48.63±1.03) vs. (41.42±2.28) U/mg protein, Day 3; P〈0.05] and the intracellular calcium content [(2.76±0.09) vs. (1.75±0.07) μmol/mg protein, Day 14; P〈0.05] in a time-dependent manner when compared with the NG group, while the ALP activity could not be blocked by Noggin protein [(48.63±1.03) vs. (47.37±0.97) U/mg protein, Day 3; P〉0.05]. These results show that high glucose levels can evoke the calcification of HASMCs by inducing osteoblastic trans-differentiation and intracellular calcium deposition via the BMP-2/Cbfa-1 pathway, which can be partially blocked by Noggin protein.