In order to demonstrate the long term protective efficacy and immunologic persistence of domestically made hepatitis B plasma derived vaccine, 371 children had been followed up for 5 to 8 years after primary vacci...In order to demonstrate the long term protective efficacy and immunologic persistence of domestically made hepatitis B plasma derived vaccine, 371 children had been followed up for 5 to 8 years after primary vaccination (10 μg×3). The results showed that the positive rate of antibody to hepatitis B surface antigen (anti HBs) in 371 subjects was 77.6% and the geometric mean titre (GMT) of anti HBs was 47.32 IU/L. The anti HBs positive rates in the subjects who had been vaccined for five, six, seven and eight years remained 83.91%, 73.68%, 81.25% and 72.24%, respectively, while the GMTs were 59.53, 43.64, 42.21 and 46.20 IU/L, respectively. The protective efficacy rate of hepatitis B vaccine was 94.26% if both HBsAg and anti HBc were considered as infective indicators, and 88.28%, if only HBsAg positive cases were taken into account. The study indicated that the domestically made hepatitis B vaccine could provide at least 5 to 8 years protection against hepatitis B infection.展开更多
利用FACE（Free Air Carbon-Dioxide Enrichment）平台技术，用水培试验研究了低氮（14mg／L）和商氮（28mg／L）水平下，大气CO2浓度升高条件下水稻蒸腾与N吸收速率的相关关系。结果表明，在CO2浓度升高条件下，水稻生物量增加了36％（...利用FACE（Free Air Carbon-Dioxide Enrichment）平台技术，用水培试验研究了低氮（14mg／L）和商氮（28mg／L）水平下，大气CO2浓度升高条件下水稻蒸腾与N吸收速率的相关关系。结果表明，在CO2浓度升高条件下，水稻生物量增加了36％（低N）和29％（高N）；总吸N量也增加达7％（低N）和5％（高N）；而总蒸腾量减少28％（低N）和10％（高N）。由于促进更多分蘖的发生。高CO2浓度使分蘖期水稻平均N吸收速率提高了31％～156％（低N）和19％～87％（高N），在其他时期无明显影响；而高CO2浓度对水稻平均蒸腾速率的影响主要表现在抽穗到灌浆末期。在对照条件下，平均蒸腾速率和平均N吸收速率呈显著正相关；但在CO2浓度升高条件下，两者相关关系不显著。说明人们所推测的“蒸腾效应”——高CO2浓度条件下降低了的蒸腾作用并非影响水稻N吸收的关键因索。展开更多
为提高目前高致病性蓝耳病(HR-PRRS)灭活疫苗的免疫效果,将经Marc-145细胞培养收获的HP-PRRS病毒原液超滤浓缩50倍,再经灭活后用Sepharose 4 Fast Flow分子筛柱层析,收集完整的病毒粒子,加油佐剂制成纯化HP-PRRS灭活疫苗。纯化后疫苗的...为提高目前高致病性蓝耳病(HR-PRRS)灭活疫苗的免疫效果,将经Marc-145细胞培养收获的HP-PRRS病毒原液超滤浓缩50倍,再经灭活后用Sepharose 4 Fast Flow分子筛柱层析,收集完整的病毒粒子,加油佐剂制成纯化HP-PRRS灭活疫苗。纯化后疫苗的攻毒保护率达到4/5以上,血清抗体检测阳转率达86%以上,均高于同批病毒液制成的未纯化灭活疫苗,且差异显著。试验证明,HR-PRRS病毒液经浓缩纯化制成疫苗后,增强了免疫效果。展开更多
文摘In order to demonstrate the long term protective efficacy and immunologic persistence of domestically made hepatitis B plasma derived vaccine, 371 children had been followed up for 5 to 8 years after primary vaccination (10 μg×3). The results showed that the positive rate of antibody to hepatitis B surface antigen (anti HBs) in 371 subjects was 77.6% and the geometric mean titre (GMT) of anti HBs was 47.32 IU/L. The anti HBs positive rates in the subjects who had been vaccined for five, six, seven and eight years remained 83.91%, 73.68%, 81.25% and 72.24%, respectively, while the GMTs were 59.53, 43.64, 42.21 and 46.20 IU/L, respectively. The protective efficacy rate of hepatitis B vaccine was 94.26% if both HBsAg and anti HBc were considered as infective indicators, and 88.28%, if only HBsAg positive cases were taken into account. The study indicated that the domestically made hepatitis B vaccine could provide at least 5 to 8 years protection against hepatitis B infection.
文摘利用FACE（Free Air Carbon-Dioxide Enrichment）平台技术，用水培试验研究了低氮（14mg／L）和商氮（28mg／L）水平下，大气CO2浓度升高条件下水稻蒸腾与N吸收速率的相关关系。结果表明，在CO2浓度升高条件下，水稻生物量增加了36％（低N）和29％（高N）；总吸N量也增加达7％（低N）和5％（高N）；而总蒸腾量减少28％（低N）和10％（高N）。由于促进更多分蘖的发生。高CO2浓度使分蘖期水稻平均N吸收速率提高了31％～156％（低N）和19％～87％（高N），在其他时期无明显影响；而高CO2浓度对水稻平均蒸腾速率的影响主要表现在抽穗到灌浆末期。在对照条件下，平均蒸腾速率和平均N吸收速率呈显著正相关；但在CO2浓度升高条件下，两者相关关系不显著。说明人们所推测的“蒸腾效应”——高CO2浓度条件下降低了的蒸腾作用并非影响水稻N吸收的关键因索。
文摘为提高目前高致病性蓝耳病(HR-PRRS)灭活疫苗的免疫效果,将经Marc-145细胞培养收获的HP-PRRS病毒原液超滤浓缩50倍,再经灭活后用Sepharose 4 Fast Flow分子筛柱层析,收集完整的病毒粒子,加油佐剂制成纯化HP-PRRS灭活疫苗。纯化后疫苗的攻毒保护率达到4/5以上,血清抗体检测阳转率达86%以上,均高于同批病毒液制成的未纯化灭活疫苗,且差异显著。试验证明,HR-PRRS病毒液经浓缩纯化制成疫苗后,增强了免疫效果。
