Cost-benefit analysis of esophageal cancer endoscopic screening in high-risk areas of China

AIM:To estimate the cost-benefit of endoscopic screening strategies of esophageal cancer(EC)in high-risk areas of China. METHODS:Markov model-based analyses were conducted to compare the net present values(NPVs)and the benefit-cost ratios(BCRs)of 12 EC endoscopic screening strategies.Strategies varied according to the targeted screening age,screening frequencies,and follow-up intervals.Model parameters were collected from population-based studies in China,published literatures,and surveillance data. RESULTS:Compared with non-screening outcomes,all strategies with hypothetical 100 000 subjects saved life years.Among five dominant strategies determined by the incremental cost-effectiveness analysis,screening once at age 50 years incurred the lowest NPV(international dollar-I$55 million)and BCR(2.52).Screening six times between 40-70 years at a 5-year interval[i.e., six times(40)f-strategy]yielded the highest NPV(I$99 million)and BCR(3.06).Compared with six times(40)fstrategy,screening thrice between 40-70 years at a 10-year interval resulted in relatively lower NPV,but the same BCR. CONCLUSION:EC endoscopic screening is cost-beneficial in high-risk areas of China.Policy-makers should consider the cost-benefit,population acceptance,and local economic status when choosing suitable screening strategies.

Cost-benefit analysis of screening for diabetic retinopathy among Chinese type 2 diabetes: decision from different perspectives of a population-based study

The purpose of this study is to explore whether it is worthwhile to launch a routine diabetic retinopathy (DR) screening for blindness pre-vention among Chinese type 2 diabetes from different perspective based on the popula-tion-based study in Kinmen, Taiwan. A total of 971 community dwelling adults previously di-agnosed with type 2 diabetes in 1991-1993 un-derwent DR screening in 1999-2002 by a panel of ophthalmologists using on-site indirect oph-thalmoscopy and 45-degree color fundus retinal photographs. The cost-benefit analysis is used to evaluate the DR screening. In terms of bene-fit-cost ratio, the different screening programs for DR could save New Taiwan Dollars (NTD) from 14.38 to 36.83 in discounted costs for each dollar incurred in different screening years from the societal viewpoint for Taiwan and save NTD from 0.81 to 1.80 in different screening years from health care payer’s perspective. The av-erage estimate of willingness-to-pay to translate into benefit yields NTD from 937.8 to 4,689 be- nefits per case due to DR screening in different screening years during 10-year follow-up. The net present value of the DR screening were NTD from -167,318 to -307,251.2 in different screening years. In conclusion, it is worthwhile to initial a routine DR screening of Chinese type 2 diabetes for blindness prevention from the societal per-spective but not from consumer decision based on the willingness-to-pay perspective.

2023—2024赛季CBA宁波队制胜关键技术指标分析

本文采用文献资料法、数理统计法、聚类分析法、对比分析法等研究方法,通过对520场CBA常规赛数据的分析,结合宁波队在常规赛中的表现,识别并评估了影响宁波队比赛结果的核心技术统计指标;同时,通过聚类分析将比赛分为发挥出色的I组和发挥平庸的II组,进一步对比分析了2组间技术指标的差异。结果显示,得分、抢断、盖帽、三分命中率等指标在2组间存在显著性差异,表明这些指标在宁波队获胜的比赛中起到了关键作用。运用单因素和多因素Logistic回归分析及Lasso回归方法,进一步筛选和验证了对宁波队比赛胜负影响最大的技术统计指标,以期为宁波队制定合理的备战策略提供支持,以助其在未来的比赛中提高竞技水平,争取更多的胜利。

CBA大前锋球员竞技水平诊断与评价研究——基于2022-2023赛季数据

采用因子分析法对2022-2023赛季CBA联赛20支球队大前锋球员的竞技水平进行诊断研究,结果:①构建出CBA大前锋竞技水平模型,具体为:“Y=0.61Y_(1)+0.16Y_(2)+0.09Y_(3)+0.07Y_(4)+0.06Y_(5)”,其中5个因子依重要程度排序为:Y_(1)“进攻效率因子”、Y_(2)“上场时间因子”、Y_(3)“三分投篮因子”、Y_(4)“罚球能力因子”、Y_(5)“投篮能力因子”。②宏观分析可见,国内大前锋球员竞技水平不及外援球员;本赛季发挥最出色的是山东队优秀外援吉伦·沃特;浙江稠州队创队史最佳战绩(常规赛第一)离不开大前锋刘泽一和摩西·赖特的出色发挥;③微观分析可见,优秀大前锋球员三分出手次数多,罚篮命中率高,但大前锋球员普遍存在投篮不稳定性的短板。

基于因子分析法的CBA小前锋球员竞技水平诊断与评价研究

本文运用因子分析法分析CBA 2022-2023赛季小前锋球员数据,构建CBA小前锋球员竞技水平的综合评价得分模型,旨在为国内小前锋球员选材、训练与参赛提供参考依据。研究结果发现:①CBA小前锋竞技水平模型为“Y=0.61Y_(1)+0.16Y_(2)+0.09Y_(3)+0.07Y_(4)”,其中Y_(1)“攻防效率因子”、Y_(2)“上场因子”、Y_(3)“三分因子”、Y_(4)“命中因子”系影响CBA小前锋球员竞技水平的主要因素,其因子影响重要程度依次递减。②CBA小前锋球员竞技水平综合得分越高说明其竞技能力越强,越有利于增加球队整体进攻能力。③CBA小前锋竞技水平综合得分前十名中,外援小前锋有六名,其中吉林九台队外援多米尼克·琼斯排名第一,其竞技水平最强。

Economic cost-benefit analysis for the agricultural use of sewage sludge treated with lime and fly ash

A tool for calculating the economic and environmental impacts of the use of byproducts of industrial processes that can substitute for perishable resources was presented.This was exemplified by fly ash(the fine fraction of ash originating from coal burned to generate electricity and collected by filtering exhaust gases leaving the furnace),added to soil as a component of sewage sludge stabilized with fly ash and lime(NVS).Application to soil of NVS has potential agricultural and environmental advantages and disadvantages.The costs and benefits of such application were calculated using both a database and expert opinions.The calculations assumed a representative assemblage of soils and crops,with weights assigned to each crop type and soil characteristic.The annual weighted benefits(additional income for the farmer)and costs per hectare reached 324$/ha and 131$/ha respectively.Major potential benefits include:Chemical fertilizer replacement,159$/ha;Improvement to the soil’s physical properties,75$/ha;Supply of vital trace elements,33$/ha.Major potential costs were:Regulatory limitations on marketing of crops pending proof of absence of risk of heavy metals or radionuclides accumulation in these crops,(17$/ha and 36$/ha respectively);Application and incorporation cost,50$/ha.The presented estimates of the costs and benefits refer to the array of soils and conditions typical to Israel.It is possible to maximize potential benefits by applying fly ash only to the most suitable agricultural soils while improper use of fly ash will increase the costs incurred from its use.

Cost-benefit Analysis of Chestnut Production in Xingtai County

On the basis of market demand survey of chestnut,this article carries out cost-benefit analysis of the chestnut production in Xingtai County,to understand the profitability and payback period of local chestnut production.It points out that chestnut production has a high rate of return on investment,and chestnut can be promoted on a large scale in Xingtai County.However,there are still some problems in the production and marketing of chestnut in Xingtai County,such as low level of technology,extensive management,low level of organization,market imperfections and weak brand consciousness.Based on these problems,corresponding recommendations are put forth.

Cost-benefit Analysis of Scale Pig Breeding in Shandong Province Based on Modified Entropy Weight-TOPSIS Model

According to the relevant statistical data in National Agricultural cost-benefit Data Compilation(2001- 2013),we use the modified entropy weight- TOPSIS model to research the cost-benefit status of scale pig breeding in Shandong Province from the perspective of comparing it with that of the entire country and 9 other main pig producing areas. The results show that compared with the national average,the cost-benefit ratio of small scale pig breeding in Shandong Province is lower,while the cost-benefit ratio of medium scale and large scale pig breeding is significantly improved; the cost-benefit ratio of small scale pig breeding in Shandong Province is basically the same as that in 9 other main pig producing areas,while the cost-benefit ratio of medium scale and large scale pig breeding is higher; the output value of main products and the purchase price of piglet are two major bottlenecks restricting the cost-benefit improvement of scale pig breeding in Shandong Province.

Study on Cost of Environmental Degradation Based on Cost-Benefit Analysis

With the rapid economic development of China,the environmental degradation brought by economic development cannot be ignored.In order to measure the cost of environmental degradation brought by land projects in the process of economic development and evaluate a land project,this paper establishes an ecological service evaluation model based on cost-benefit method to analyze the cost and benefit of land development projects from a new perspective,and explore effective strategies to alleviate environmental degradation.

Cost-benefit analysis of trading strategies in the stock index futures market

With the introduction of many derivatives into the capital market,including stock index futures,the trading strategies in financial markets have been gradually enriched.However,there is still no theoretical model that can determine whether these strategies are effective,what the risks are,and how costly the strategies are.We built an agent-based cross-market platform that includes five stocks and one stock index future,and constructed an evaluation system for stock index futures trading strategies.The evaluation system includes four dimensions:effectiveness,risk,occupation of capital,and impact cost.The results show that the informed strategy performs well in all aspects.The risk of the technical strategy is relatively higher than that of the other strategies.Moreover,occupation of capital and impact cost are both higher for the arbitrage strategy.Finally,the wealth of noise traders is almost lost.

Evaluating and Improving the Effectiveness of Vehicle Inspection and Maintenance Programs: A Cost-Benefit Analysis Framework

Motor vehicle inspection and maintenance (I/M) programs are designed to identify high-emitting vehicles and mitigate their impacts on air quality and climate. I/M programs have been traditionally ranked superior among various vehicle emission control measures by the results of cost-benefit analysis, based on the assumption that these programs will achieve the targeted emission reduction outcomes. However, the actual effects of I/M programs may be greatly uncertain and when this uncertainty is taken into account, these programs may become suboptimal. This study develops a new a cost-benefit analysis framework that links various program design consideration, such as program participation rate, identification rate and effective repair rate, to the public health benefits as well as costs of the programs. This framework helps decision makers to investigate minimum implementation requirements that at least ensure the benefits are greater than the costs of implementing the programs in order to improve the overall effectiveness of the I/M programs. To illustrate the applications of the framework, it was applied to a particulate matter oriented I/M program targeting all diesel-fueled vehicles in the city of Bangkok, Thailand, a large metropolitan area that has been suffering from severe ambient PM pollution mainly attributable to its wide use of diesel-fueled vehicles and motorcycles. It was found that the health benefits achieved from the program are sensitive to several key program design elements, including participation rate and problem vehicle identification rate, fraction of effective repairs and illegal operation rate. Other variables, such as the testing cut-points and vehicle population growth rate, only have modest effects on the overall emission reduction and consequent health benefits. Overall, the performance of multiple variables associated with I/M program design needs to be improved simultaneous in order to achieve the targeted benefits of the program.

Transradial Versus Transfemoral Approach for Percutaneous Coronary Intervention in Elderly Patients in China： A Retrospective Analysis

Objective To compare hospital costs and clinical outcomes between transradial intervention （TRI） and transfemoral intervention （TFI） in elderly patients aged over 65 years. Methods We identified 1229 patients aged over 65 years who underwent percutaneous coronary intervention （PCI） in Fuwai Hospital, Beijing, China, between January 1 and December 31, 2010. Total hospital costs and in-hospital outcomes were compared between TRI and TFI. An inverse probability weighting （IPW） model was introduced to control potential biases. Results Patients who underwent TRI were younger, less often female, more likely to receive PCI for single-vessel lesions, and less likely to undergo the procedure for ostial lesions. TRI was associated with a cost saving of CNY7495 （95%CI： CNY4419-10 420）. Such differences were mainly driven by lower PCI-related costs. TRI patients had shorter length of stay （1.9 days, 95%CI： 1.1-2.7 days）, shorter post-procedural stay （0.7 days, 95%CI： 0.3-1.1 days）, and fewer major adverse cardiac events （adjusted odds ratio = 0.47, 95%CI： 0.31-0.73）. There was no statistical significance in the incidence of post-PCI bleeding between TRI and TFI （P〉0.05）. Such differences remained consistent in clinically relevant subgroups of acute myocardial infarction, acute coronary syndrome, and stable angina. Conclusion The use of TRI in patients aged over 65 years was associated with significantly reduced hospital costs and more favorable clinical outcomes.

Cost benefit analysis of the use of tranexamic acid in primary lower limb arthroplasty: A retrospective cohort study

AIM: To examine the cost benefit conferred by the perioperative administration of intravenous tranexamic acid(TXA) in lower limb arthroplasty.METHODS: This study evaluates the use of TXA in 200 consecutive lower limb arthroplasties performed in a single surgeon series. The initial 100 patients(control group) underwent surgery without perioperative administration of TXA while the subsequent 100 patients(TXA group) all received 1 g TXA at the time of induction of anaesthesia. Pre- and post-operative haemoglobin, platelet count, haematocrit, the use of blood product post-operatively, length of stay were examined. A financial analysis of both groups was then undertaken. RESULTS: The mean age of patients in both groups was 63 ± 13 years. There were no significant differences between groups in terms of gender(P = 0.47), proportion of total hip replacement to total knee replacement(P = 0.25) or pre-operative haemoglobin(P = 0.43). In the control group, the transfusion rate was 22%. In the TXA group, the transfusion rate dropped to 2%(P < 0.001). The mean post-operative haemoglobin was 10.82 ± 1.55g/dL in the control group vs 11.33 ± 1.27 g/dL in the TXA group(P = 0.01). The total cost of transfused blood products was €11055 and €603 respectively. The mean length of stay in the control group was 6.53 ± 5.93 d vs 5.47 ± 4.26 d in the TXA group(P = 0.15) leading to an estimated financial saving of €114586. There was one pulmonary embolus in the control group and one deep venous thrombosis in the TXA group.CONCLUSION: Intravenous TXA reduces blood loss in lower limb arthroplasty. This leads to lower transfusion rates, shorter length of stay in hospital and significant financial savings.

Long-term costs and benefits analysis of China’s low-carbon policies

China’s long-term,low-emission development goals will hinge on effective low-carbon policies.Therefore,it is valuable to evaluate the costs and benefits of low-carbon policy packages to ensure that low-carbon development concepts and strategies can be well integrated into the policy making process.This work uses the Low-carbon Policy Assessment(LPA)model to assess long-term costs and benefits of climate and energy policies in China under the reference(RS)scenario and the low-carbon(LC)scenario,which includes 25 additional climate and energy policies.In the LC scenario,both energy-related CO2 emissions and total greenhouse gas(GHG)emissions peak around 2030,achieving China’s Nationally Determined Contribution(NDC)target.Of the policies included in the LC scenario,the five with the highest GHG mitigation potential beyond China’s existing policies are:fluorinated gas(F-gas)substitution,a renewable portfolio standard,carbon pricing,carbon capture utilization and storage(CCUS),and a fuel economy standard for heavy duty vehicles(HDVs).In addition to reducing GHG emissions,these policies decrease particulate emissions and associated premature deaths,which would otherwise reduce China’s GDP by nearly 1.5%in 2050.Together,these policies have the potential to promote significant low-carbon prosperity in China.

Early infant male circumcision:Systematic review,risk-benefit analysis,and progress in policy

AIM To determine whether recent evidence-based United States polices on male circumcision(MC) apply to comparable Anglophone countries,Australia and New Zealand.METHODS Articles in 2005 through 2015 were retrieved from PubM ed using the keyword "circumcision" together with 36 relevant subtopics.A further PubM ed search was performed for articles published in 2016.Searches of the EMBASE and Cochrane databases did not yield additional citable articles.Articles were assessed for quality and those rated 2+ and above according to the Scottish Intercollegiate Grading System were studied further.The most relevant andrepresentative of the topic were included.Bibliographies were examined to retrieve further key references.Randomized controlled trials,recent high quality systematic reviews or meta-analyses(level 1++ or 1+ evidence) were prioritized for inclusion.A risk-benefit analysis of articles rated for quality was performed.For efficiency and reliability,recent randomized controlled trials,metaanalyses,high quality systematic reviews and large welldesigned studies were used if available.Internet searches were conducted for other relevant information,including policies and Australian data on claims under Medicare for MC.RESULTS Evidence-based policy statements by the American Academy of Pediatrics(AAP) and the Centers for Disease Control and Prevention(CDC) support infant and later age male circumcision(MC) as a desirable public health measure.Our systematic review of relevant literature over the past decade yielded 140 journal articles that met our inclusion criteria.Together,these showed that early infant MC confers immediate and lifelong benefits by protecting against urinary tract infections having potential adverse long-term renal effects,phimosis that causes difficult and painful erections and "ballooning" during urination,inflammatory skin conditions,inferior penile hygiene,candidiasis,various sexually transmissible infections in both sexes,genital ulcers,and penile,prostate and cervical cancer.Our risk-benefit analysis showed that benefits exceeded procedural risks,which are predominantly minor,by up to 200 to 1.We estimated that more than 1 in 2 uncircumcised males will experience an adverse foreskin-related medical condition over their lifetime.Wide-ranging evidence from surveys,physiological measurements,and the anatomical location of penile sensory receptors responsible for sexual sensation strongly and consistently suggested that MC has no detrimental effect on sexual function,sensitivity or pleasure.United States studies showed that early infant MC is cost saving.The evidence supporting early infant MC has further strengthened since the positive AAP and CDC reviews.CONCLUSION Affirmative MC policies are needed in Australia and New Zealand.Routine provision of accurate,unbiased education,and access in public hospitals,will maximize health and financial benefits.

Building-integrated renewable energy policy analysis in China

With the dramatic development of renewable energy all over the world,and for purpose of adjusting energy structure,the Ministry of Construction of China plans to promote the large scale application of renewable energy in buildings. In order to ensure the validity of policy-making,this work firstly exerts a method to do cost-benefit analysis for three kinds of technologies such as building-integrated solar hot water (BISHW) system,building-integrated photovoltaic (BIPV) technology and ground water heat pump (GWHP). Through selecting a representative city of every climate region,the analysis comes into different results for different climate regions in China and respectively different suggestion for policy-making. On the analysis basis,the Ministry of Construction (MOC) and the Ministry of Finance of China (MOF) united to start-up Building-integrated Renewable Energy Demonstration Projects (BIREDP) in 2006. In the demonstration projects,renewable energy takes place of traditional energy to supply the domestic hot water,electricity,air-conditioning and heating. Through carrying out the demonstration projects,renewable energy related market has been expanded. More and more relative companies and local governments take the opportunity to promote the large scale application of renewable energy in buildings.

Empirical Analysis of the Typical Breeding Pattern of Clam in Hongdao Town and the Preliminary Estimates of Costs and Benefits

Based on the survey data about clam breeding farmers in Hongdao Town in August 2011,this paper analyzes the production and operation of typical clam breeding pattern,and estimates the costs and benefits. Through the analysis of operation conditions and economic conditions of Hongdao clam breeding,this paper aims to explore a more reasonable and effective breeding pattern so as to reduce breeding costs and market risks,and increase breeding farmers' income.

Comparative Cost Benefit Analysis of Different Solid Waste Management Scenarios in Basrah, Iraq

Solid Waste Management (SWM) system in Basrah has deteriorated recently to the point that only limited waste collection is undertaken in certain urban areas and disposal is largely to uncontrolled dump sites. In this study, the technical, economical, and environmental aspects of three SWM scenarios were investigated aiming to compare the scenarios and select the most appropriate one for implementation. Scenario 1 was to consider waste disposal into a sanitary landfill. Scenario 2 added waste transportation to transfer station before disposal to a sanitary landfill. Scenario 3 considered waste sorting, recycling and composting followed by landfill disposal in an integrated treatment disposal facility. The current open dumping practice was considered as the baseline scenario. According to economic analysis, the benefits from the revenues of selling the produced recyclables and compost did not improve the ranking of scenario 3. However, scenario 3 has gained positive recognition due to the environmental benefits of waste recycling. Therefore, final recommendations were in favour of scenario 3, which has been approved by the UNICEF, as well. Currently the recommended scenario is under implementation in Basrah, Iraq.

CBA前锋竞技表现的评价指标与实证分析——基于2022—2023赛季CBA季后赛

基于2022—2023赛季CBA季后赛比赛情况,分析前锋运动员在比赛中竞技表现能力,结果显示:不同球队在季后赛期间,前锋运动员的战术策略各不相同,因而运动员在各指标中的数据存在一定的差异;由因子分析得知,前锋运动员在攻击效率、罚球能力、防守篮板能力、投篮准确性以及比赛规范性和前场篮板能力等多个方面都有出色的表现,并且攻击效率的权重最高。教练员在制订训练计划时,可以根据这些权重来合理分配训练的时间和精力,以提高运动员的整体竞技表现。