Effect of negative mood,serum inflammatory factors,miR-155,and brain-derived neurotrophic factor

BACKGROUND Abdominal postoperative patients are susceptible to postoperative depression resulting from pain and stress,which can hinder their rehabilitation.Acupuncture has shown potential to relieve this condition.AIM To analyze the mechanism by which acupuncture relieves postoperative depression in patients post-abdominal surgery.METHODS Abdominal postoperative patients with depression between January 2015 and December 2023 at the First Affiliated Hospital of Heilongjiang University of Chinese Medicine were enrolled.Patients were divided into two groups using the random throwing method:Observation(250 cases,fluoxetine hydrochloride+acupuncture treatment)and control(250 cases,fluoxetine hydrochloride treatment).Changes in negative emotions Hamilton Depression Scale 24,serum inflammatory factors[tumor necrosis factorα,interleukin(IL)-1β,IL-6],miR-155 expression levels,and BDNF levels were assessed.RESULTS Significant improvements were observed in the observation group compared to the control group in all assessed parameters after six weeks(P<0.05).This suggests that the combination of fluoxetine hydrochloride and acupuncture may be more effective in managing postoperative depression than medication alone.CONCLUSION Acupuncture complies with the principle of traditional Chinese medicine syndrome differentiation and ensures the pertinence and effectiveness of treatment.In addition,it not only actively improves depressive symptoms but also effectively regulates the serum level of inflammatory factors.

Effects of hormone replacement therapy on mood and sleep quality in menopausal women

BACKGROUND Hormone replacement therapy is an effective treatment strategy for the management of symptoms in naturally menopausal women.However,some patients report experiencing adverse effects.AIM To analyze the effects of hormone replacement therapy in menopausal female patients.METHODS A total of 152 menopausal female patients admitted to the Gynecology Department of the Ganzhou Maternal and Child Health Hospital between January 2021 and December 2023 were divided into the observation group(n=76,conventional treatment+hormone replacement therapy)and the control group(n=76,conventional treatment only)via random casting.The improvement observed in the following items were compared between the groups:Kupperman menopausal index(KMI),emotional state[The Positive and Negative Affect Scale(PANAS)],sleep quality[Self-Rating Scale of Sleep(SRSS)],treatment effectiveness,and treatment safety.RESULTS The modified KMI and SRSS scores of the observation group were lower than those of the control group after three rounds of treatment.The improvement in the PANAS score observed in the observation group was greater than that observed in the control group(P<0.05).The total treatment effectivity rate in the observation group was higher than that in the control group(86.84%vs 96.05%,χ2=4.121,P=0.042).The incidence rate of adverse reactions in the two groups was comparable(6.58%vs 9.21%,χ2=0.361,P=0.547).CONCLUSION Hormone replacement therapy effectively improved the clinical symptoms,actively channeled negative emotions,and improved the quality of sleep in menopausal patients,indicating its effectiveness and safety.

Vividly Colored Accessories and Mood Changes in Patients Undergoing Breast Surgery

Few studies have examined the impacts of color stimuli on perioperative mood and quality of recovery;thus, this randomized controlled trial aimed to assess impacts of vividly colored accessories on mood and quality of recovery after breast surgery. This single-center, single-blind randomized controlled trial included 36 participants (all aged ≥ 20 years) who were randomized into intervention (n = 19) and control groups (n = 17). The intervention group received vividly colored accessories. The primary and secondary study outcomes were patient mood, evaluated using a two-dimensional mood scale, and postoperative recovery, evaluated using Quality of Recovery-15, which were assessed on postoperative day 3. There were no statistical intergroup differences in the scores of the Two-Dimensional Mood Scale (11.2 [intervention group] vs. 10.4 [control group], P = 0.75) and Quality of Recovery-15 (126.8 [intervention group] vs. 129.3 [control group], P = 0.73). Thus, the use of vividly colored accessories by patients undergoing breast surgery was not found to affect patients’ mood and quality of recovery.

Hormone replacement therapy for menopausal mood swings and sleep quality:The current evidence

Marked alterations in the normal female hormonal milieu in the perimenopausal period significantly affect women’s health,leading to decreased well-being,psychological distress,and impaired quality of life.Common menopausal symp-toms include hot flashes,sleep and mood changes,fatigue,weight gain,and urogenital disturbances.Clinicians often neglect mood swings and disrupted sleep,although those can significantly limit the productivity of women and impair their cognitive function and mental health.Evidence-based management should include a personalized,holistic approach to alleviate symptoms and careful consideration of the risks vs benefits of hormone replacement therapy(HRT),with due consideration of personal preferences.A research paper in the recent issue of the World Journal of Psychiatry by Liu et al investigated the role of HRT in altering mood changes and impaired sleep quality in menopausal women,which helps us to understand the benefits of this treatment approach.

Research status of hormone replacement therapy on mood and sleep quality in menopausal women

Menopausal syndrome is a common disease of clinical women,which refers to a series of physical and mental symptoms caused by the fluctuation or reduction of sex hormones before and after menopause.Many of these patients have sleep and mood abnormalities that affect their health and quality of life.At present,the understanding of it is gradually improving.This paper mainly analyzes its back-ground and current treatment.

Color Expression and Mood Creation in Imagery Oil Painting

Oil painting is a traditional Western painting form.With the introduction of China and the influence of China’s traditional painting and aesthetics,the painting style became more distinctive,expanding a new development direction of oil painting,and thus imagery oil painting came into being.Color,as the most important element in imagery oil painting,mainly plays the role of mood creation and emotional expression.Many creators are good at injecting their thoughts and emotions into the paintings through color matching,so as to enhance the artistic expression of the paintings.This paper analyzes the color expression characteristics of imagery oil painting and explores the color expression techniques in imagery oil painting and mood creation of imagery oil painting from several aspects.

A Study on the Mental Space of Subjunctive Mood

Cognitive linguistics offers a novel approach to studying and elucidating language phenomena,with the theory of mental spaces being particularly adept at interpreting many“non-canonical”linguistic occurrences and providing a fresh cognitive framework.The subjunctive mood,one of the three primary moods in English,is integral to English grammar.Yet,it remains a contentious topic within the field,with a lack of consensus among different linguistic schools regarding this significant grammatical category.The substantial role of human cognition in the construction and interpretation of the subjunctive mood’s meaning has been infrequently explored.This paper,from a cognitive perspective,employs the theory of mental spaces to discuss the English subjunctive mood,addressing the questions of its theoretical foundation,the reasons for its use,and the methods of its application.

面向对象度量——MOOD算法集及其应用分析

面向对象软件的主要特性包括抽象性、封装性、继承性和多态性等 .本文在分析这些特性的基础上 ,介绍了一种能对这些特性进行全面度量的算法集 ,并对这种算法集在实际应用中可能出现的问题进行了分析 。

立体定向手术治疗重型脑干出血临床疗效分析

目的 探讨立体定向手术治疗重型脑干出血临床疗效分析。方法 对收治的80例重型脑干出血患者治疗情况进行回顾性分析,选取时间2021年1月至2022年12月,只愿接受保守治疗患者40例作为对照组,愿意接受立体定向手术治疗患者40例作为研究组,比较两组治疗7d时GCS评分情况,比较两组治疗30d时NSE、IL-6水平情况,比较两组治疗90d时mRs评分情况,比较两组患者家属心理情绪情况。结果 治疗7d时,研究组GCS评分9-15分的百分比高于对照组,死亡百分比低于对照组(P<0.05);与治疗前比较,治疗30d时两组NSE水平、IL-6水平均有所下降(P<0.05),与对照组比较,治疗30d时研究组NSE水平、IL-6水平均更低(P<0.05);治疗90d时,研究组mRs评分在0-2级者百分比高于对照组,死亡百分比低于对照组(P<0.05);治疗后两组患者家属心理不良情绪均有所减轻(P<0.05),与对照组比较,研究组治疗90d时的SDS、SAS评分均更低(P<0.05)。结论 重型脑干出血患者治疗中采用立体定向手术治疗,相较于常规保守治疗,患者机体炎症反应缓解幅度更大,患者死亡率显著降低,疾病预后有明显改善,且能够有效减轻患者家属的心理负担、心理压力,值得积极应用,临床疗效更为优良。

双相障碍患者的风险决策偏好:来自三水平元分析的证据

本研究采用三水平元分析定量估计双相患者与健康个体的风险决策偏好差异,并检验该差异是否受到样本特征和测量特征的调节。基于71篇文献和176个效应量的元分析发现,双相患者比健康个体更偏好风险寻求(Hedges'g=0.301),且这一偏好在风险态度量表(Hedges'g=0.624)、行为实验任务(Hedges'g=0.252)和日常风险行为(Hedges'g=0.312)中都稳定存在。同时,该差异还受到年龄(β=0.009)和心境阶段的调节,其中不论心境阶段如何,双相患者均比健康个体更偏好风险寻求(缓解期:Hedges'g=0.245;<轻>躁狂期:Hedges'g=0.604;重性抑郁期:Hedges'g=0.417)。此外,在行为实验任务中,该差异受到年龄(β=0.012)和地区的调节。特别是欧洲(Hedges'g=0.419)和南美洲(Hedges'g=0.420)的患者,以及在爱荷华赌博任务(Hedges'g=0.396)和剑桥赌博任务(Hedges'g=0.220)中的患者,均比健康个体更偏好风险寻求;而在日常态度和行为中,该差异仅受到心境阶段的调节,<轻>躁狂期患者(Hedges'g=0.747)比健康个体更偏好风险寻求。本研究首次通过多种风险决策偏好测量类型探讨双相障碍与风险决策的关系,得出了较稳定的结果,并提出未来研究应充分考虑心境阶段、任务类型等因素的影响,深入挖掘双相障碍影响风险决策的心理机制,为双相障碍的临床管理和心理教育提供参考。

基于Brown-Mood中位数检验的小企业债信评级体系

债信评级是通过挖掘评级数据与违约风险的关系,评价一笔债务回收的可能性及不同等级违约损失率的大小。基于Brown-Mood中位数检验建立小企业债信评级体系。创新与特色:①根据某个指标的非违约样本中位数显著大于违约样本的中位数,则该指标越能将非违约与违约样本区分开的思路构造Brown-Mood中位数检验统计量值,遴选通过检验、即违约鉴别力显著的指标。改变了绝大多数现有研究未以违约鉴别力显著为指标遴选标准的不足。②在相关系数大的一对指标中,删除Brown-Mood中位数检验统计量值小的指标,在避免了指标反映信息冗余的同时,也避免了指标的误删。③根据指标的违约鉴别力越强、指标权重就应越大的思路对指标赋权,确保了违约鉴别力越大的指标,权重也越大。④根据非违约样本的债信得分中位数显著大于违约样本的债信得分中位数,则债信得分越能显著区分违约状态、债信评分体系越合理的思路,检验债信评分体系的合理性,开拓了债信评分体系检验的新思路。实证表明:包括资产负债率、恩格尔系数等24个指标的小企业债信评级体系具有显著的违约鉴别力,在债信评级时,应重点关注恩格尔系数、行业景气指数等企业外部宏观环境因素以及法人代表汽车及不动产价值、担任该职务时间等法人代表基本情况因素。

六指标MOOD度量网络软件尺度因子拓扑优化模型

针对复杂网络环境下软件质量测评技术的特点,基于最新计算机网络软件质量管理理论,提出MOOD度量方法对软件质量进行体系测评,定义了六指标体系算法作为软件评估度量体系,首次对Mc-Call模型、Boehm模型和ISO/IEC 9126模型3种典型的计算机软件质量优化模型进行系统结构拓扑和测评误差分析,并提出采用WAF尺度因子对结果拓扑进行评价。仿真结果表明,3种优化模型误差率都得到有效降低,趋于0.01,比传统度量方法误差降低23%。研究成果为软件质量管理提供了有效的理论依据。

大学生焦虑情绪问题的现况调查及其影响因素研究

[目的]了解并分析大学生的焦虑情绪问题现况及相关影响因素,为制定对应的干预措施提供参考。[方法]利用GAD-7广泛性焦虑障碍量表,通过线上问卷调查方式对3086名在校大学生进行调查,采用χ^(2)检验和多因素Logistic回归方法分析其影响因素。[结果]调查对象焦虑阳性检出率为45.0%,其中:轻度为35.6%、中度为7.3%、重度为2.1%。单因素分析结果显示,大学生焦虑状况在常住地、年级、父母文化、主要抚养人、家庭关系、家庭经济状况6个因素上的分布差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,常住地(OR=0.849)、年级(OR=1.642)、家庭关系(OR=0.504)、家庭经济状况(OR=0.489)与焦虑情绪问题相关(P均<0.05)。[结论]大学生焦虑情绪与常住地、年级、家庭关系、家庭经济状况等因素有关,需要营造积极的校园学习氛围和良好的家庭氛围,关注大学生压力状况,帮助大学生提高适应能力。

On the Usage of the Subjunctive Mood in English

The subjunctive mood is one of the most difficult English grammar items for most English learners. In this thesis,the author discusses the usage of the subjunctive mood in English,especially its usage in English subordinate clauses. At the same time,the author provides a lot of examples. In the author's opinion,as long as the English learners find out the rules of it and practice it more,they will definitely grasp the subjunctive mood and use it correctly and skillfully.

两独立样本的Wilcoxon符号秩检验和Brown—Mood中位数检验的功效比较

本文针对两独立样本数据的Wilcoxon符号秩检验和Brown—Mood中位数检验的相对效率进行测度进而比较两种检验的功效。本文先通过类比的方法，基于渐进相对效率理论对二者的功效做出一个初步的判断得出Wilcoxon符号秩检验功效较高的结论；再通过蒙特卡洛模拟，运用R软件计算对于正态分布下不同参数的两总体两检验的功效。从模拟的结果也可以看出，Wilcoxon符号秩检验的检验效果较Brown—Mood检验而言要好。

Gut microbiota in autism and mood disorders

The hypothesis of an important role of gut microbiota in the maintenance of physiological state into the gastrointestinal(GI)system is supported by several studies that have shown a qualitative and quantitative alteration of the intestinal flora in a number of gastrointestinal and extra-gastrointestinal diseases.In the last few years,the importance of gut microbiota impairment in the etiopathogenesis of pathology such as autism,dementia and mood disorder,has been raised.The evidence of the inflammatory state alteration,highlighted in disorders such as schizophrenia,major depressive disorder and bipolar disorder,strongly recalls the microbiota alteration,highly suggesting an important role of the alteration of GI system also in neuropsychiatric disorders.Up to now,available evidences display that the impairment of gut microbiota plays a key role in the development of autism and mood disorders.The application of therapeutic modulators of gut microbiota to autism and mood disorders has been experienced only in experimental settings to date,with few but promising results.A deeper assessment of the role of gut microbiota in the development of autism spectrum disorder(ASD),as well as the advancement of the therapeutic armamentarium for the modulation of gut microbiota is warranted for a better management of ASD and mood disorders.

Effects of music and music therapy on mood in neurological patients

Mood disorder and depressive syndromes represent a common comorbid condition in neurological disorders witha prevalence rate that ranges between 20% and 50% of patients with stroke, epilepsy, multiple sclerosis, and Parkinson's disease. Notwithstanding, these conditions are often under-diagnosed and under-treated in the clinical practice and negatively affect the functional recovery, the adherence to treatment, the quality of life, and even the mortality risk. In addition, a bidirectional association between depression and neurological disorders may be possible being that depressive syndromes may be considered as a risk factor for certain neurological diseases. Despite the large amount of evidence regarding the effects of music therapy(MT) and other musical interventions on different aspects of neurological disorders, no updated article reviewing outcomes such as mood, emotions, depression, activity of daily living and so on is actually available; for this reason, little is known about the effectiveness of music and MT on these important outcomes in neurological patients. The aim of this article is to provide a narrative review of the current literature on musical interventions and their effects on mood and depression in patients with neurological disorders. Searching on Pub Med and Psyc Info databases, 25 studies corresponding to the inclusion criteria have been selected; 11 of them assess the effects of music or MT in Dementia, 9 explore the efficacy on patients with Stroke, and 5 regard other neurological diseases like Multiple Sclerosis, Amyotrophic Lateral Sclerosis/motor neuron disease, Chronic quadriplegia, Parkinson's Disease, and Acquired Brain dysfunctions. Selected studies are based on relational and rehabilitative music therapy approaches or concern music listening interventions. Most of the studies support the efficacy of MT and other musical interventions on mood, depressive syndromes, and quality of life on neurological patients.

Effects of mindfulness-based psychological care on mood and sleep of leukemia patients in chemotherapy

Purpose:The aim of this research was to explore the benefits of mindfulness-based psychological care(MBPC)and assess whether the intervention would be beneficial in reducing insomnia and emotional symptoms of leukemia patients receiving chemotherapy.Methods:A randomized control design study was applied in two hematology departments in a hospital in Zhengzhou.Patients in the experimental group received mindfulness-based psychological care(MBPC),and those in the control group received conventional care.Anxiety,depression,and sleeping problems were measured using the Self-Rating Anxiety Scale,Self-Rating Depression Scale,and the Pittsburgh Sleep Quality Index.Results:Statistically significant differences were observed among anxiety,depression,and sleeping problems between the two groups in the post-test(P<0.05).A significant decrease in anxiety and depression and an improvement in sleep were observed between pre-and post-interventions(P<0.05)in the experimental group.Conclusions:MBPC significantly improved sleep quality and mood of the experimental group.It is an effective complementary therapy for leukemia treatment that is inexpensive,noninvasive,and associated with relaxation and pain reduction.

The Effects of a Single Bout of Exercise on Mood and Self-Esteem in Clinically Diagnosed Mental Health Patients

Objectives: Research has highlighted the importance of regular exercise within the general population and mental health groups in regard to mood and self-esteem, as well as single bout exercise within the general population. However, research into single bout exercise in mental health population is lacking. This study investigated the impact of a single bout of exercise, on mood and self-esteem, in patients with a wider clinical mental health diagnosis. Design: A quantitative questionnaire was completed immediately pre and post a single, 45 minute bout of moderate intensity exercise, consisting of the Brunel Universal Mood States (BRUMS) questionnaire and the Rosenberg Self Esteem Scale (RSE). Methods: Participants attending a mental health hospital with a clinical mental health diagnosis (N = 54) completed the questionnaire. Information regarding physical activity levels, mental health diagnosis and length of hospital stay were collated. Results: A significant improvement was identified on the RSE as well as the BRUMS (depression, anger, confusion, anxious tension and vigour) over time. Conclusion: The significant findings highlight the importance of exercise promotion within this population group, and the potentially beneficial role that a single bout of exercise can have on mood and self-esteem in patients experiencing mental health problems.

Changes in Autonomic Nervous System Activity and Mood of Healthy People after Mindfulness Art Therapy Short Version

The aim of this study was to investigate changes in autonomic nervous system (ANS) activity and mood caused by Mindfulness Art Therapy Short version (MATS). The participants were 20 Japanese college students who were separated into high and low risk groups based on the median score of the General Health Questionnaire (GHQ). MATS consisted of mindfulness exercise and making of art in one session. ANS activity (TP: total energy, LF/HF: sympathetic nervous, HF: parasympathetic nervous system, LF: both sympathetic and parasympathetic) and mood (TA: tension arousal, EA: energy arousal) were measured psychologically before and after MATS. In the high risk group, TP significantly decreased and LF, HF, and LF/HF did not change significantly;while TA significantly decreased and EA significantly increased. In the low risk group, TP and LF significantly increased and HF and LF/HF did not change significantly;while TA significantly decreased and EA showed a non-significant increase. These results suggest that MATS affects the ANS differently for participants with different states of mental health, and particularly promotes activity in low-risk participants. Psychologically, MATS decreased tension or anxiety and increased energy. These findings justify further use of this therapy.