Objective: Discuss the analysis of the results of control and elimination of coal-burning fluorosis in Chongqing, and evaluate the effect of prevention and control. Methods: Dean’s method was used to investigate the ...Objective: Discuss the analysis of the results of control and elimination of coal-burning fluorosis in Chongqing, and evaluate the effect of prevention and control. Methods: Dean’s method was used to investigate the fluorosis for the local children whose ages ranged from 8 to 12 years old, the use of improved stoves in residential households, the drying of corn and pepper for human consumption, and the results were evaluated and discussed according to the national standard for the control and elimination of coal-burning fluorosis. Results: The prevalence rate of dental fluorosis borne-disease in children whose ages ranged from 8 to 12 years old was about 11.28% in 661 historically diseased villages in 100 townships and in 13 districts and counties of Chongqing city. The correct utilization rates of improved stoves, qualified improved stoves, and qualified stoves were 100%, 98.82%, and 99.45%, respectively. The correct drying rates of corn and pepper for human consumption were 99.88% and 99.75% respectively. There are 24 uncontrolled villages, 225 controlled villages, and 412 villages in eliminated disease zones in administrative villages. There are 4 villages and counties in uncontrolled, 4 in controlled, and 5 eliminated areas in districts and counties. Conclusion: Fluorosis borne-disease caused by coal-burning in Chongqing has reached the control and elimination targets of the twelfth Five-year plan.展开更多
In order to output sine wave with small degree of distortion and improve stability,a type of inverter power supply is designed based on harmonic elimination pulse-width modulation(PWM)control.The rectifier and filter ...In order to output sine wave with small degree of distortion and improve stability,a type of inverter power supply is designed based on harmonic elimination pulse-width modulation(PWM)control.The rectifier and filter are added to input circuit of the inverter.Single-phrase full-bridge inverter performs the function of converting direct current into alternating current(DC/AC).In the control circuit,single chip micyoco(SCM)AT89C2051 is used for main control chip to accomplish the hardware design of the control system.A given value of output frequency of the inverter is input in the way of coding.According to the output frequency code which is read,SCM AT89C2051 defined harmonic elimination PWM control data which will be selected.Through internal timing control,the switches are switched under this provision of PWM control data.Then the driving signals of the switches in the inverter are output from I/O of SCM AT89C2051 to realize harmonic elimination PWM control.The results show that adding Newton homotopic algorithm of harmonic elimination PWM control to corresponding software of the control system can make the quality of output voltage of the inverter higher and it will have broad application prospects.展开更多
The phenomenon of anti-symmetrical bifurcation of periodic solutionsoccurring near an integral manifold is the intrinsic cause resulting in harmonic resonanceover-voltage in power systems. Due to this discovery, the p...The phenomenon of anti-symmetrical bifurcation of periodic solutionsoccurring near an integral manifold is the intrinsic cause resulting in harmonic resonanceover-voltage in power systems. Due to this discovery, the principle of eliminating resonance byusing anti-bifurcation technique is presented, which makes that the theoretical bases of verymeasure to eliminate resonance are unified firstly from a point of view of basic theory. Ourdiscussion models depend on a class of nonlinear control model. Using the direct Lyapunov method, acomplete theoretical proof is given in accordance with the measure of eliminating resonance byconnecting nonlinear resistor in series to the neutral point of P. T., and the feedback control lawbeing applied. It comprises the action of parameters of resistor to eliminate resonance and theactual process of eliminating resonance, i.e., to go against bifurcation process which forces thebig harmonic solutions to retreat to the integral manifold gradually and disappear eventually, whichby using the nonlinear controllers. This makes it sure that the intrinsic cause of resonance iseliminated thoroughly. The obtained theory results and computing results are better than thepresented results.展开更多
Since the water supply crisis in the Taihu Lake on May 29,2007,the control of the Taihu Lake has achieved remarkable results,and the eutrophication has been greatly reduced.Existing problems are as follows:outbreaks o...Since the water supply crisis in the Taihu Lake on May 29,2007,the control of the Taihu Lake has achieved remarkable results,and the eutrophication has been greatly reduced.Existing problems are as follows:outbreaks of blue-green alga still appear seriously every year,and there is no goal to eliminate outbreaks of blue-green alga;the load into the lake greatly exceeds the environmental capacity;reed wetlands are greatly reduced;there is still the possibility of a water supply crisis;the research of eliminating outbreak of blue-green alga is weak.In this paper,the experience of controlling the Taihu Lake is summarized,and the ultimate goals of eliminating eutrophication and outbreaks of blue-green alga and restoring wetlands and biodiversity are proposed.Control measures are proposed,such as deepening the promotion of the lake chief system,establishing the lake chief system in an all-round way,and increasing applied scientific and technological efforts and capital investment.The necessity and possibility of further controlling the Taihu Lake to eliminate outbreaks of blue-green alga should be recognized.Relying on controlling eutrophication alone cannot eliminate outbreaks of blue-green alga.The point that phosphorus control is the key to eliminate outbreaks of blue-green alga is not suitable for the Taihu Lake.The integration ideas of"three types"of technologies should be innovated.The first one is"double reduction and double increase"measures to eliminate eutrophication,of which"double reduction"is to reduce external point sources and non-point sources and internal blue-green alga in sediment;for external sources,the treatment standard of sewage plants should be paid special attention to.The second one is"double algae removal"measures to salvage blue-green alga,suppresses and kills algae.The blue-green alga on the surface,middle and bottom of water should be thoroughly salvaged and eliminated from various water areas.The third one is"double restoration"measures to restore wetlands and biodiversity.The area of wetlands should be restored to the area from the 1960s to the 1970s before outbreaks of blue-green alga,and vegetation coverage reaches 25%-30%.The Taihu Lake is controlled in different waters to ensure water supply safety in water sources.Five suggestions are proposed,such as revising the"Overall Plan for the Comprehensive Treatment of Water Environment in the Taihu Lake Basin"again,incorporating the goal of eliminating outbreaks of blue-green alga in the plan,setting up this research topic,greatly improving sewage treatment standards in local legislation.展开更多
When a differential field <em>K</em> having <em>n</em> commuting derivations is given together with two finitely generated differential extensions <em>L</em> and <em>M</em&...When a differential field <em>K</em> having <em>n</em> commuting derivations is given together with two finitely generated differential extensions <em>L</em> and <em>M</em> of <em>K</em>, an important problem in differential algebra is to exhibit a common differential extension <em>N</em> in order to define the new differential extensions <em>L</em><span style="white-space:nowrap;"><span style="white-space:nowrap;">∩</span></span><em>M </em>and the smallest differential field <span style="white-space:nowrap;">(<em>L</em>,<em>M</em> ) <span style="white-space:nowrap;"><span style="white-space:nowrap;">⊂</span></span> <em>N</em></span> containing both <em>L</em> and <em>M</em>. Such a result allows to generalize the use of complex numbers in classical algebra. Having now two finitely generated differential modules<em> L</em> and <em>M</em> over the non-commutative ring <span style="white-space:nowrap;"><em>D</em> = <em>K </em>[<em>d</em><sub>1</sub>,...,<em>d</em><sub>n</sub>] = <em>K</em> [<em>d</em>]</span> of differential operators with coefficients in <em>K</em>, we may similarly look for a differential module <em>N</em> containing both <em>L</em> and <em>M </em>in order to define <span style="white-space:nowrap;"><em>L</em>∩<em>M</em></span> and <span style="white-space:nowrap;"><em>L</em>+<em>M</em></span>. This is <em>exactly</em> the situation met in linear or non-linear OD or PD control theory by selecting the inputs and the outputs among the control variables. However, in many recent books and papers, we have shown that controllability was a <em>built-in</em> property of a control system, not depending on the choice of inputs and outputs. The purpose of this paper is thus to revisit control theory by showing the specific importance of the two previous problems and the part plaid by <em>N</em> in both cases for the parametrization of the control system. An important tool will be the study of <em>differential correspondence</em><em>s</em>, a modern name for what was called <em>B<span style="white-space:nowrap;"><span style="white-space:nowrap;">ä</span></span>cklund problem</em> during the last century, namely the elimination theory for groups of variables among systems of linear or nonlinear OD or PD equations. The main difficulty is to revisit <em>differential homological algebra</em> by using noncommutative localization as a way to generalize the symbolic calculus in the style of Heaviside and Mikusinski. Finally, when <em>M</em> is a <em>D</em>-module, this paper is using for the first time the fact that the system <span style="white-space:nowrap;"><em>R</em> = <em>hom<sub>K</sub></em> (<em>M</em>,<em>K</em>)</span> is a <em>D</em>-module for the Spencer operator acting on sections, avoiding thus behaviours, trajectories and signal spaces in a purely formal way, contrary to a few recent works on this difficult subject.展开更多
Under complex grid conditions,the grid voltage usually has an imbalance,low order harmonics,and a small of DC bias.When the grid voltage contains low order harmonics and a small amount of DC bias component,the inverte...Under complex grid conditions,the grid voltage usually has an imbalance,low order harmonics,and a small of DC bias.When the grid voltage contains low order harmonics and a small amount of DC bias component,the inverter’s output current cannot meet the grid connection requirements,and there is a three-phase current imbalance in the control strategy of common VSG under unbalanced voltage.A theoretical analysis of non-ideal power grids is carried out,and a VSG control strategy under complex operating conditions is proposed.Firstly,the third-order generalized integrator(TOGI)is used to eliminate the influence of the DC component of grid voltage.An improved delay signal cancellation(DSC)method is proposed to control the balance current and power fluctuation under unbalanced voltage based on the method of common VSG positive and negative sequence separation,It also eliminates the harmonic of command current.Then,the improved quasi proportional resonant controller(QPR)cascaded PI is used to suppress the harmonic current further so that the harmonic content of grid-connected current can meet the grid-connected requirements and achieve the three-phase current balance.Finally,the proposed strategy is verified by simulation under the control objectives of the current balance,active power,and reactive power constant.展开更多
Schistosomiasis is a water borne parasitic disease of global importance and with ongoing control the disease endemic landscape is changing.In sub-Saharan Africa,for example,the landscape is becoming ever more heteroge...Schistosomiasis is a water borne parasitic disease of global importance and with ongoing control the disease endemic landscape is changing.In sub-Saharan Africa,for example,the landscape is becoming ever more heterogeneous as there are several species of Schistosoma that respond in different ways to ongoing preventive chemotherapy and the inter-sectoral interventions currently applied.The major focus of preventive chemotherapy is delivery of praziquantel by mass drug administration to those shown to be,or presumed to be,at-risk of infection and disease.In some countries,regional progress may be uneven but in certain locations there are very real prospects to transition from control into interruption of transmission,and ultimately elimination.To manage this transition requires reconsideration of some of the currently deployed diagnostic tools used in surveillance and downward realignment of existing prevalence thresholds to trigger mass treatment.A key challenge will be maintaining and if possible,expanding the current donation of praziquantel to currently overlooked groups,then judging when appropriate to move from mass drug administration to selective treatment.In so doing,this will ensure the health system is adapted,primed and shown to be cost-effective to respond to these changing disease dynamics as we move forward to 2020 targets and beyond.展开更多
Significant progress has been made in the last 25 years to reduce the malaria burden,but considerable challenges remain.These gains have resulted from large investments in a range of control measures targeting malaria...Significant progress has been made in the last 25 years to reduce the malaria burden,but considerable challenges remain.These gains have resulted from large investments in a range of control measures targeting malaria.Fana and co-authors find a strong relationship between education level and net usage with malaria parasitemia in pregnant women,suggesting the need for targeted control strategies.Mayala and co-workers find important links between agriculture and malaria with implications for inter-sectoral collaboration for malaria control.展开更多
Background: Malaria cases have declined significantly along the China-Myanmar border in the past 10 years and this region is going through a process from control to elimination.The aim of this study is to investigate ...Background: Malaria cases have declined significantly along the China-Myanmar border in the past 10 years and this region is going through a process from control to elimination.The aim of this study is to investigate the epidemiology of malaria along the border,will identify challenges in the progress from control to elimination.Methods:: National reported malaria cases from China and Myanmar,along with the data of 18 Chinese border counties and 23 townships in Myanmar were obtained from a web-based diseases information reporting system in China and the national malaria control program of Myanmar,respectively.Epidemiological data was analyzed,including the number of reported cases,annual parasite index and proportion of vivax infection.Spatial mapping of the annual parasite index(API)at county or township level in 2014 and 2018 was performed by ArcGIS.The relationship of malaria endemicity on both sides of the border was evaluated by regression analysis.Results: The number of reported malaria cases and API declined in the border counties or townships.In 2014,392 malaria cases were reported from 18 Chinese border counties,including 8.4%indigenous cases and 91.6%imported cases,while the highest API(0.11)was occurred in Yingjiang County.There have been no indigenous cases reported since 2017,but 164 imported cases were reported in 2018 and 97.6%were imported from Myanmar.The average API in 2014 in 23 Myanmar townships was significantly greater than that of 18 Chinese counties(P<0.01).However,the API decreased significantly in Myanmar side from 2014 to 2018(P<0.01).The number of townships with an API between 0 and 1 increased to 15 in 2018,compared to only five in 2014,while still four townships had API>10.Plasmodium vivax was the predominant species along the border.The number of reported malaria cases and the proportion of vivax infection in the 18 Chinese counties were strongly correlated with those of the 23 Myanmar townships(P<0.05).Conclusions: Malaria elimination is approaching along the China-Myanmar border.However,in order to achieve the malaria elimination in this region and prevent the re-establishment of malaria in China after elimination,continued political,financial and scientific commitment is required.展开更多
Background:Onchocerciasis is found predominantly in Africa where large scale vector control started in 1974.Registration and donation of ivermectin by Merck&Co in 1987 enabled mass treatment with ivermectin in all...Background:Onchocerciasis is found predominantly in Africa where large scale vector control started in 1974.Registration and donation of ivermectin by Merck&Co in 1987 enabled mass treatment with ivermectin in all endemic countries in Africa and the Americas.Although elimination of onchocerciasis with ivermectin was considered feasible only in the Americas,recently it has been shown possible in Africa too,necessitating fundamental changes in technical and operational approaches and procedures.Main body:The American programme(OEPA)operating in onchocerciasis epidemiological settings similar to the mild end of the complex epidemiology of onchocerciasis in Africa,has succeeded in eliminating onchocerciasis from 4 of its 6 endemic countries.This was achieved through biannual mass treatment with ivermectin of 85%of the eligible population,and monitoring and evaluation using serological tests in children and entomological tests.The first African programme(OCP)had a head start of nearly two decades.It employed vector control and accumulated lots of knowledge on the dynamics of onchocerciasis elimination over a wide range of epidemiological settings in the vast expanse of its core area.OCP made extensive use of modelling and operationalised elimination indicators for entomological evaluation and epidemiological evaluation using skin snip procedures.The successor African programme(APOC)employed mainly ivermectin treatment.Initially its objective was to control onchocerciasis as a public health problem but that objective was later expanded to include the elimination of onchocerciasis where feasible.Building on the experience with onchocerciasis elimination of the OCP,APOC has leveraged OCP’s vast modelling experience and has developed operational procedures and indicators for evaluating progress towards elimination and stopping ivermectin mass treatment of onchocerciasis in the complex African setting.Conclusions:Following the closure of APOC in 2015,implementation of onchocerciasis elimination in Africa appears to overlook all the experience that has been accumulated by the African programmes.It is employing predominantly American processes that were developed in a dissimilar setting from the complex African onchocerciasis setting.This is impeding progress towards decisions to stop intervention in many areas that have reached the elimination point.This article summarizes lessons learned in Africa and their importance for achieving elimination in Africa by 2025.展开更多
Background:An estimated 25 million people are currently infected with onchocerciasis(a parasitic infection caused by the filarial nematode Onchocerca volvulus and transmitted by Simulium vectors),and 99%of these are i...Background:An estimated 25 million people are currently infected with onchocerciasis(a parasitic infection caused by the filarial nematode Onchocerca volvulus and transmitted by Simulium vectors),and 99%of these are in sub-Saharan Africa.The African Programme for Onchocerciasis Control closed in December 2015 and the World Health Organization has established a new structure,the Expanded Special Project for the Elimination of Neglected Tropical Diseases for the coordination of technical support for activities focused on five neglected tropical diseases in Africa,including onchocerciasis elimination.Aims:In this paper we argue that despite the delineation of a reasonably well-defined elimination strategy,its implementation will present particular difficulties in practice.We aim to highlight these in an attempt to ensure that they are well understood and that effective plans can be laid to solve them by the countries concerned and their international partners.Conclusions:A specific concern is the burden of disease caused by onchocerciasis-associated epilepsy in hyperendemic zones situated in countries experiencing difficulties in strengthening their onchocerciasis control programmes.These difficulties should be identified and programmes supported during the transition from morbidity control to interruption of transmission and elimination.展开更多
文摘Objective: Discuss the analysis of the results of control and elimination of coal-burning fluorosis in Chongqing, and evaluate the effect of prevention and control. Methods: Dean’s method was used to investigate the fluorosis for the local children whose ages ranged from 8 to 12 years old, the use of improved stoves in residential households, the drying of corn and pepper for human consumption, and the results were evaluated and discussed according to the national standard for the control and elimination of coal-burning fluorosis. Results: The prevalence rate of dental fluorosis borne-disease in children whose ages ranged from 8 to 12 years old was about 11.28% in 661 historically diseased villages in 100 townships and in 13 districts and counties of Chongqing city. The correct utilization rates of improved stoves, qualified improved stoves, and qualified stoves were 100%, 98.82%, and 99.45%, respectively. The correct drying rates of corn and pepper for human consumption were 99.88% and 99.75% respectively. There are 24 uncontrolled villages, 225 controlled villages, and 412 villages in eliminated disease zones in administrative villages. There are 4 villages and counties in uncontrolled, 4 in controlled, and 5 eliminated areas in districts and counties. Conclusion: Fluorosis borne-disease caused by coal-burning in Chongqing has reached the control and elimination targets of the twelfth Five-year plan.
文摘In order to output sine wave with small degree of distortion and improve stability,a type of inverter power supply is designed based on harmonic elimination pulse-width modulation(PWM)control.The rectifier and filter are added to input circuit of the inverter.Single-phrase full-bridge inverter performs the function of converting direct current into alternating current(DC/AC).In the control circuit,single chip micyoco(SCM)AT89C2051 is used for main control chip to accomplish the hardware design of the control system.A given value of output frequency of the inverter is input in the way of coding.According to the output frequency code which is read,SCM AT89C2051 defined harmonic elimination PWM control data which will be selected.Through internal timing control,the switches are switched under this provision of PWM control data.Then the driving signals of the switches in the inverter are output from I/O of SCM AT89C2051 to realize harmonic elimination PWM control.The results show that adding Newton homotopic algorithm of harmonic elimination PWM control to corresponding software of the control system can make the quality of output voltage of the inverter higher and it will have broad application prospects.
文摘The phenomenon of anti-symmetrical bifurcation of periodic solutionsoccurring near an integral manifold is the intrinsic cause resulting in harmonic resonanceover-voltage in power systems. Due to this discovery, the principle of eliminating resonance byusing anti-bifurcation technique is presented, which makes that the theoretical bases of verymeasure to eliminate resonance are unified firstly from a point of view of basic theory. Ourdiscussion models depend on a class of nonlinear control model. Using the direct Lyapunov method, acomplete theoretical proof is given in accordance with the measure of eliminating resonance byconnecting nonlinear resistor in series to the neutral point of P. T., and the feedback control lawbeing applied. It comprises the action of parameters of resistor to eliminate resonance and theactual process of eliminating resonance, i.e., to go against bifurcation process which forces thebig harmonic solutions to retreat to the integral manifold gradually and disappear eventually, whichby using the nonlinear controllers. This makes it sure that the intrinsic cause of resonance iseliminated thoroughly. The obtained theory results and computing results are better than thepresented results.
文摘Since the water supply crisis in the Taihu Lake on May 29,2007,the control of the Taihu Lake has achieved remarkable results,and the eutrophication has been greatly reduced.Existing problems are as follows:outbreaks of blue-green alga still appear seriously every year,and there is no goal to eliminate outbreaks of blue-green alga;the load into the lake greatly exceeds the environmental capacity;reed wetlands are greatly reduced;there is still the possibility of a water supply crisis;the research of eliminating outbreak of blue-green alga is weak.In this paper,the experience of controlling the Taihu Lake is summarized,and the ultimate goals of eliminating eutrophication and outbreaks of blue-green alga and restoring wetlands and biodiversity are proposed.Control measures are proposed,such as deepening the promotion of the lake chief system,establishing the lake chief system in an all-round way,and increasing applied scientific and technological efforts and capital investment.The necessity and possibility of further controlling the Taihu Lake to eliminate outbreaks of blue-green alga should be recognized.Relying on controlling eutrophication alone cannot eliminate outbreaks of blue-green alga.The point that phosphorus control is the key to eliminate outbreaks of blue-green alga is not suitable for the Taihu Lake.The integration ideas of"three types"of technologies should be innovated.The first one is"double reduction and double increase"measures to eliminate eutrophication,of which"double reduction"is to reduce external point sources and non-point sources and internal blue-green alga in sediment;for external sources,the treatment standard of sewage plants should be paid special attention to.The second one is"double algae removal"measures to salvage blue-green alga,suppresses and kills algae.The blue-green alga on the surface,middle and bottom of water should be thoroughly salvaged and eliminated from various water areas.The third one is"double restoration"measures to restore wetlands and biodiversity.The area of wetlands should be restored to the area from the 1960s to the 1970s before outbreaks of blue-green alga,and vegetation coverage reaches 25%-30%.The Taihu Lake is controlled in different waters to ensure water supply safety in water sources.Five suggestions are proposed,such as revising the"Overall Plan for the Comprehensive Treatment of Water Environment in the Taihu Lake Basin"again,incorporating the goal of eliminating outbreaks of blue-green alga in the plan,setting up this research topic,greatly improving sewage treatment standards in local legislation.
文摘When a differential field <em>K</em> having <em>n</em> commuting derivations is given together with two finitely generated differential extensions <em>L</em> and <em>M</em> of <em>K</em>, an important problem in differential algebra is to exhibit a common differential extension <em>N</em> in order to define the new differential extensions <em>L</em><span style="white-space:nowrap;"><span style="white-space:nowrap;">∩</span></span><em>M </em>and the smallest differential field <span style="white-space:nowrap;">(<em>L</em>,<em>M</em> ) <span style="white-space:nowrap;"><span style="white-space:nowrap;">⊂</span></span> <em>N</em></span> containing both <em>L</em> and <em>M</em>. Such a result allows to generalize the use of complex numbers in classical algebra. Having now two finitely generated differential modules<em> L</em> and <em>M</em> over the non-commutative ring <span style="white-space:nowrap;"><em>D</em> = <em>K </em>[<em>d</em><sub>1</sub>,...,<em>d</em><sub>n</sub>] = <em>K</em> [<em>d</em>]</span> of differential operators with coefficients in <em>K</em>, we may similarly look for a differential module <em>N</em> containing both <em>L</em> and <em>M </em>in order to define <span style="white-space:nowrap;"><em>L</em>∩<em>M</em></span> and <span style="white-space:nowrap;"><em>L</em>+<em>M</em></span>. This is <em>exactly</em> the situation met in linear or non-linear OD or PD control theory by selecting the inputs and the outputs among the control variables. However, in many recent books and papers, we have shown that controllability was a <em>built-in</em> property of a control system, not depending on the choice of inputs and outputs. The purpose of this paper is thus to revisit control theory by showing the specific importance of the two previous problems and the part plaid by <em>N</em> in both cases for the parametrization of the control system. An important tool will be the study of <em>differential correspondence</em><em>s</em>, a modern name for what was called <em>B<span style="white-space:nowrap;"><span style="white-space:nowrap;">ä</span></span>cklund problem</em> during the last century, namely the elimination theory for groups of variables among systems of linear or nonlinear OD or PD equations. The main difficulty is to revisit <em>differential homological algebra</em> by using noncommutative localization as a way to generalize the symbolic calculus in the style of Heaviside and Mikusinski. Finally, when <em>M</em> is a <em>D</em>-module, this paper is using for the first time the fact that the system <span style="white-space:nowrap;"><em>R</em> = <em>hom<sub>K</sub></em> (<em>M</em>,<em>K</em>)</span> is a <em>D</em>-module for the Spencer operator acting on sections, avoiding thus behaviours, trajectories and signal spaces in a purely formal way, contrary to a few recent works on this difficult subject.
基金National Natural Science Foundation of China(61863023).
文摘Under complex grid conditions,the grid voltage usually has an imbalance,low order harmonics,and a small of DC bias.When the grid voltage contains low order harmonics and a small amount of DC bias component,the inverter’s output current cannot meet the grid connection requirements,and there is a three-phase current imbalance in the control strategy of common VSG under unbalanced voltage.A theoretical analysis of non-ideal power grids is carried out,and a VSG control strategy under complex operating conditions is proposed.Firstly,the third-order generalized integrator(TOGI)is used to eliminate the influence of the DC component of grid voltage.An improved delay signal cancellation(DSC)method is proposed to control the balance current and power fluctuation under unbalanced voltage based on the method of common VSG positive and negative sequence separation,It also eliminates the harmonic of command current.Then,the improved quasi proportional resonant controller(QPR)cascaded PI is used to suppress the harmonic current further so that the harmonic content of grid-connected current can meet the grid-connected requirements and achieve the three-phase current balance.Finally,the proposed strategy is verified by simulation under the control objectives of the current balance,active power,and reactive power constant.
基金The COUNTDOWN consortium receives funding from the Research and Evidence Division,Department for International Development,UKLATT received financial support from the Bill&Melinda Gates Foundation,Grand Challenges Explorations.
文摘Schistosomiasis is a water borne parasitic disease of global importance and with ongoing control the disease endemic landscape is changing.In sub-Saharan Africa,for example,the landscape is becoming ever more heterogeneous as there are several species of Schistosoma that respond in different ways to ongoing preventive chemotherapy and the inter-sectoral interventions currently applied.The major focus of preventive chemotherapy is delivery of praziquantel by mass drug administration to those shown to be,or presumed to be,at-risk of infection and disease.In some countries,regional progress may be uneven but in certain locations there are very real prospects to transition from control into interruption of transmission,and ultimately elimination.To manage this transition requires reconsideration of some of the currently deployed diagnostic tools used in surveillance and downward realignment of existing prevalence thresholds to trigger mass treatment.A key challenge will be maintaining and if possible,expanding the current donation of praziquantel to currently overlooked groups,then judging when appropriate to move from mass drug administration to selective treatment.In so doing,this will ensure the health system is adapted,primed and shown to be cost-effective to respond to these changing disease dynamics as we move forward to 2020 targets and beyond.
文摘Significant progress has been made in the last 25 years to reduce the malaria burden,but considerable challenges remain.These gains have resulted from large investments in a range of control measures targeting malaria.Fana and co-authors find a strong relationship between education level and net usage with malaria parasitemia in pregnant women,suggesting the need for targeted control strategies.Mayala and co-workers find important links between agriculture and malaria with implications for inter-sectoral collaboration for malaria control.
基金This work was supported by the Natural Science Foundation of Shanghai(No.18ZR1443400)the National Important Scientific&Technological Project 2018ZX10101002-002)the Forge Ahead Together for Elimination Towards Malaria free China–Myanmar border and National Malaria Elimination Program of China.
文摘Background: Malaria cases have declined significantly along the China-Myanmar border in the past 10 years and this region is going through a process from control to elimination.The aim of this study is to investigate the epidemiology of malaria along the border,will identify challenges in the progress from control to elimination.Methods:: National reported malaria cases from China and Myanmar,along with the data of 18 Chinese border counties and 23 townships in Myanmar were obtained from a web-based diseases information reporting system in China and the national malaria control program of Myanmar,respectively.Epidemiological data was analyzed,including the number of reported cases,annual parasite index and proportion of vivax infection.Spatial mapping of the annual parasite index(API)at county or township level in 2014 and 2018 was performed by ArcGIS.The relationship of malaria endemicity on both sides of the border was evaluated by regression analysis.Results: The number of reported malaria cases and API declined in the border counties or townships.In 2014,392 malaria cases were reported from 18 Chinese border counties,including 8.4%indigenous cases and 91.6%imported cases,while the highest API(0.11)was occurred in Yingjiang County.There have been no indigenous cases reported since 2017,but 164 imported cases were reported in 2018 and 97.6%were imported from Myanmar.The average API in 2014 in 23 Myanmar townships was significantly greater than that of 18 Chinese counties(P<0.01).However,the API decreased significantly in Myanmar side from 2014 to 2018(P<0.01).The number of townships with an API between 0 and 1 increased to 15 in 2018,compared to only five in 2014,while still four townships had API>10.Plasmodium vivax was the predominant species along the border.The number of reported malaria cases and the proportion of vivax infection in the 18 Chinese counties were strongly correlated with those of the 23 Myanmar townships(P<0.05).Conclusions: Malaria elimination is approaching along the China-Myanmar border.However,in order to achieve the malaria elimination in this region and prevent the re-establishment of malaria in China after elimination,continued political,financial and scientific commitment is required.
文摘Background:Onchocerciasis is found predominantly in Africa where large scale vector control started in 1974.Registration and donation of ivermectin by Merck&Co in 1987 enabled mass treatment with ivermectin in all endemic countries in Africa and the Americas.Although elimination of onchocerciasis with ivermectin was considered feasible only in the Americas,recently it has been shown possible in Africa too,necessitating fundamental changes in technical and operational approaches and procedures.Main body:The American programme(OEPA)operating in onchocerciasis epidemiological settings similar to the mild end of the complex epidemiology of onchocerciasis in Africa,has succeeded in eliminating onchocerciasis from 4 of its 6 endemic countries.This was achieved through biannual mass treatment with ivermectin of 85%of the eligible population,and monitoring and evaluation using serological tests in children and entomological tests.The first African programme(OCP)had a head start of nearly two decades.It employed vector control and accumulated lots of knowledge on the dynamics of onchocerciasis elimination over a wide range of epidemiological settings in the vast expanse of its core area.OCP made extensive use of modelling and operationalised elimination indicators for entomological evaluation and epidemiological evaluation using skin snip procedures.The successor African programme(APOC)employed mainly ivermectin treatment.Initially its objective was to control onchocerciasis as a public health problem but that objective was later expanded to include the elimination of onchocerciasis where feasible.Building on the experience with onchocerciasis elimination of the OCP,APOC has leveraged OCP’s vast modelling experience and has developed operational procedures and indicators for evaluating progress towards elimination and stopping ivermectin mass treatment of onchocerciasis in the complex African setting.Conclusions:Following the closure of APOC in 2015,implementation of onchocerciasis elimination in Africa appears to overlook all the experience that has been accumulated by the African programmes.It is employing predominantly American processes that were developed in a dissimilar setting from the complex African onchocerciasis setting.This is impeding progress towards decisions to stop intervention in many areas that have reached the elimination point.This article summarizes lessons learned in Africa and their importance for achieving elimination in Africa by 2025.
基金RC received funding for his work from the European Research Council(ERC grant No.671055)MGB thanks the Wellcome Trust(grants Nos.085133/Z/08/Z and 092677/Z/10/Z)The funders had no role in the writing of the manuscript or the decision to publish。
文摘Background:An estimated 25 million people are currently infected with onchocerciasis(a parasitic infection caused by the filarial nematode Onchocerca volvulus and transmitted by Simulium vectors),and 99%of these are in sub-Saharan Africa.The African Programme for Onchocerciasis Control closed in December 2015 and the World Health Organization has established a new structure,the Expanded Special Project for the Elimination of Neglected Tropical Diseases for the coordination of technical support for activities focused on five neglected tropical diseases in Africa,including onchocerciasis elimination.Aims:In this paper we argue that despite the delineation of a reasonably well-defined elimination strategy,its implementation will present particular difficulties in practice.We aim to highlight these in an attempt to ensure that they are well understood and that effective plans can be laid to solve them by the countries concerned and their international partners.Conclusions:A specific concern is the burden of disease caused by onchocerciasis-associated epilepsy in hyperendemic zones situated in countries experiencing difficulties in strengthening their onchocerciasis control programmes.These difficulties should be identified and programmes supported during the transition from morbidity control to interruption of transmission and elimination.