Polyvinylpyrrolidone-iodine (PVP-I) complexes are widely used in the medical and health field due to its strong antimicrobial properties and good biocompatibility,but their water solubility negates the possibility to ...Polyvinylpyrrolidone-iodine (PVP-I) complexes are widely used in the medical and health field due to its strong antimicrobial properties and good biocompatibility,but their water solubility negates the possibility to be used as a wound dressing.In this work,the problem of PVP dissolving in water was solved by the method of thermally crosslinking,and it was found that the thermally crosslinked PVP nanofiber heated at 170 ℃ for 6 h had good liquid absorption capacity,stability and good fiber morphology.In addition,the thermally crosslinked PVP nanofiber is complexed with I2 to endow it with excellent antibacterial properties.It has been demonstrated to have good biocompatibility through cytotoxicity and hemolysis experiments,which provides the possibility for it to be a dressing for the treatment of infectious wounds.展开更多
Microencapsulation of phase change materials(Micro PCMs) has been paid special attention because of their extensive applications in saving and releasing energy. Micro PCMs containing paraffin with a melting point of ...Microencapsulation of phase change materials(Micro PCMs) has been paid special attention because of their extensive applications in saving and releasing energy. Micro PCMs containing paraffin with a melting point of 55 ℃ in polystyrene-divinylbenzene(P(St-DVB)) were prepared by suspension-like polymerization. The characterization of microcapsules by FTIR, DSC and TG proved that paraffin had been successfully encapsulated and the proportion of encapsulated paraffin was 49.8%—58.5%. The effects of polyvinylpyrrolidone(PVP) with different molecular weights serving as the suspension stabilizer were investigated in detail. The results illustrated that the type of PVP had a significant influence on the particle size of Micro PCMs. The average diameter of Micro PCMs decreased with an increasing molecular weight of PVP. Moreover, the crosslinker-postaddition method was adopted in this study to improve the morphology of P(St-DVB) Micro PCMs. SEM images showed that when the DVB was added at the 2nd hour of polymerization the morphology of obtained P(St-DVB) Micro PCMs exhibited good sphericity since it could avoid the influence of cross-linker agent during the nucleation period.展开更多
基金supported by the Jilin Provincial Development and Reform Commission Industrial Technology Research and Development Project,China(No.2023C039-5)the Jilin Province Science and Technology Development Plan Project,China(No.20210204107YY)the Jilin Province Health Technology Capability Enhancement Project,China(No.2021LC028).
文摘Polyvinylpyrrolidone-iodine (PVP-I) complexes are widely used in the medical and health field due to its strong antimicrobial properties and good biocompatibility,but their water solubility negates the possibility to be used as a wound dressing.In this work,the problem of PVP dissolving in water was solved by the method of thermally crosslinking,and it was found that the thermally crosslinked PVP nanofiber heated at 170 ℃ for 6 h had good liquid absorption capacity,stability and good fiber morphology.In addition,the thermally crosslinked PVP nanofiber is complexed with I2 to endow it with excellent antibacterial properties.It has been demonstrated to have good biocompatibility through cytotoxicity and hemolysis experiments,which provides the possibility for it to be a dressing for the treatment of infectious wounds.
基金financially supported by the National Natural Science Foundation of China (No. 20973022 and 11472048)the State Key Laboratory of Catalytic Materials and Reaction Engineering (RIPP, SINOPEC)
文摘Microencapsulation of phase change materials(Micro PCMs) has been paid special attention because of their extensive applications in saving and releasing energy. Micro PCMs containing paraffin with a melting point of 55 ℃ in polystyrene-divinylbenzene(P(St-DVB)) were prepared by suspension-like polymerization. The characterization of microcapsules by FTIR, DSC and TG proved that paraffin had been successfully encapsulated and the proportion of encapsulated paraffin was 49.8%—58.5%. The effects of polyvinylpyrrolidone(PVP) with different molecular weights serving as the suspension stabilizer were investigated in detail. The results illustrated that the type of PVP had a significant influence on the particle size of Micro PCMs. The average diameter of Micro PCMs decreased with an increasing molecular weight of PVP. Moreover, the crosslinker-postaddition method was adopted in this study to improve the morphology of P(St-DVB) Micro PCMs. SEM images showed that when the DVB was added at the 2nd hour of polymerization the morphology of obtained P(St-DVB) Micro PCMs exhibited good sphericity since it could avoid the influence of cross-linker agent during the nucleation period.
