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Computational Experiments for Complex Social Systems:Experiment Design and Generative Explanation 被引量:2
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作者 Xiao Xue Deyu Zhou +5 位作者 Xiangning Yu Gang Wang Juanjuan Li Xia Xie Lizhen Cui Fei-Yue Wang 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第4期1022-1038,共17页
Powered by advanced information technology,more and more complex systems are exhibiting characteristics of the cyber-physical-social systems(CPSS).In this context,computational experiments method has emerged as a nove... Powered by advanced information technology,more and more complex systems are exhibiting characteristics of the cyber-physical-social systems(CPSS).In this context,computational experiments method has emerged as a novel approach for the design,analysis,management,control,and integration of CPSS,which can realize the causal analysis of complex systems by means of“algorithmization”of“counterfactuals”.However,because CPSS involve human and social factors(e.g.,autonomy,initiative,and sociality),it is difficult for traditional design of experiment(DOE)methods to achieve the generative explanation of system emergence.To address this challenge,this paper proposes an integrated approach to the design of computational experiments,incorporating three key modules:1)Descriptive module:Determining the influencing factors and response variables of the system by means of the modeling of an artificial society;2)Interpretative module:Selecting factorial experimental design solution to identify the relationship between influencing factors and macro phenomena;3)Predictive module:Building a meta-model that is equivalent to artificial society to explore its operating laws.Finally,a case study of crowd-sourcing platforms is presented to illustrate the application process and effectiveness of the proposed approach,which can reveal the social impact of algorithmic behavior on“rider race”. 展开更多
关键词 Agent-based modeling computational experiments cyber-physical-social systems(CPSS) generative deduction generative experiments meta model
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Design and analysis of an advanced thermal management system for the solar close observations and proximity experiments spacecraft 被引量:1
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作者 Liu Liu Kangli Bao +4 位作者 Jianchao Feng Xiaofei Zhu Haoyu Wang Xiaofeng Zhang Jun Lin 《Astronomical Techniques and Instruments》 CSCD 2024年第1期52-61,共10页
In this paper,the mission and the thermal environment of the Solar Close Observations and Proximity Experiments(SCOPE)spacecraft are analyzed,and an advanced thermal management system(ATMS)is designed for it.The relat... In this paper,the mission and the thermal environment of the Solar Close Observations and Proximity Experiments(SCOPE)spacecraft are analyzed,and an advanced thermal management system(ATMS)is designed for it.The relationship and functions of the integrated database,the intelligent thermal control system and the efficient liquid cooling system in the ATMS are elaborated upon.For the complex thermal field regulation system and extreme space thermal environment,a modular simulation and thermal field planning method are proposed,and the feasibility of the planning algorithm is verified by numerical simulation.A solar array liquid cooling system is developed,and the system simulation results indicate that the temperatures of the solar arrays meet the requirements as the spacecraft flies by perihelion and aphelion.The advanced thermal management study supports the development of the SCOPE program and provides a reference for the thermal management in other deep-space exploration programs. 展开更多
关键词 Solar Close Observations and Proximity experiments Adaptive thermal control method Thermal field planning method Pumped liquid cooling system Advanced thermal management system
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Plasma nitrogen fixation system with dual-loop enhancement for improved energy efficiency and its efficacy for lettuce cultivation
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作者 韩泽阳 张梦雪 +8 位作者 张頔 何欣 井天军 葛知轩 李玉鸽 朱童 任云鸿 仲崇山 季方 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第1期82-92,共11页
Plasma nitrogen fixation(PNF)has been emerging as a promising technology for greenhouse gasfree and renewable energy-based agriculture.Yet,most PNF studies seldom address practical application-specific issues.In this ... Plasma nitrogen fixation(PNF)has been emerging as a promising technology for greenhouse gasfree and renewable energy-based agriculture.Yet,most PNF studies seldom address practical application-specific issues.In this work,we present the development of a compact and automatic PNF system for on-site agricultural applications.The system utilized a gliding-arc discharge as the plasma source and employed a dual-loop design to generate NO_(x)from air and water under atmospheric conditions.Experimental results showed that the system with a dualloop design performs well in terms of energy costs and production rates.Optimal operational parameters for the system were determined through experimentation,resulting in an energy cost of 13.9 MJ mol^(-1)and an energy efficiency of 16 g kWh^(-1)for NO_(3)^(-)production,respectively.Moreover,the concentration of exhausted NO_(x)was below the emission standards.Soilless lettuce cultivation experiments demonstrated that NO_(x)^(-)produced by the PNF system could serve as liquid nitrate nitrogen fertilizer.Overall,our work demonstrates the potential of the developed PNF system for on-site application in the production of green-leaf vegetables. 展开更多
关键词 plasma nitrogen fixation gliding arc soilless cultivation LETTUCE
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Mechanical heterogeneity characterization of coal materials based on nano-indentation experiments
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作者 ZHANG Qi LI Xiang-chun +3 位作者 LI Biao MENG Jun-qing NIE Bai-sheng LU Wei-dong 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第9期3142-3155,共14页
To investigate the complex macro-mechanical properties of coal from a micro-mechanical perspective,we have conducted a series of micro-mechanical experiments on coal using a nano-indentation instrument.These experimen... To investigate the complex macro-mechanical properties of coal from a micro-mechanical perspective,we have conducted a series of micro-mechanical experiments on coal using a nano-indentation instrument.These experiments were conducted under both dynamic and static loading conditions,allowing us to gather the micro-mechanical parameters of coal for further analysis of its micro-mechanical heterogeneity using the box counting statistical method and the Weibull model.The research findings indicate that the load–displacement curves of the coal mass under the two different loading modes exhibit noticeable discreteness.This can be attributed to the stress concentration phenomenon caused by variations in the mechanical properties of the micro-units during the loading process of the coal mass.Consequently,there are significant fluctuations in the micro-mechanical parameters of the coal mass.Moreover,the mechanical heterogeneity of the coal at the nanoscale was confirmed based on the calculation results of the standard deviation coefficient and Weibull modulus of the coal body’s micromechanical parameters.These results reveal the influence of microstructural defects and minerals on the uniformity of the stress field distribution within the loaded coal body,as well as on the ductility characteristics of the micro-defect structure.Furthermore,there is a pronounced heterogeneity in the micromechanical parameters.Furthermore,we have established a relationship between the macro and micro elastic modulus of coal by applying the Mori-Tanaka homogenization method.This relationship holds great significance for revealing the micro-mechanical failure mechanism of coal. 展开更多
关键词 nano-indentation experiment MICROMECHANICS heterogeneity characterization COAL
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Effects of water and nitrogen rate on grain-filling characteristics under high-low seedbed cultivation in winter wheat
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作者 Junming Liu Zhuanyun Si +6 位作者 Shuang Li Lifeng Wu Yingying Zhang Xiaolei Wu Hui Cao Yang Gao Aiwang Duan 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第12期4018-4031,共14页
A high-efficiency mode of high-low seedbed cultivation(HLSC)has been listed as the main agricultural technology to increase land utilization ratio and grain yield in Shandong Province,China.However,limited information... A high-efficiency mode of high-low seedbed cultivation(HLSC)has been listed as the main agricultural technology to increase land utilization ratio and grain yield in Shandong Province,China.However,limited information is available on the optimized water and nitrogen management for yield formation,especially the grain-filling process,under HLSC mode.A three-year field experiment with four nitrogen rates and three irrigation rates of HLSC was conducted to reveal the response of grain-filling parameters,grain weight percentage of spike weight(GPS),spike moisture content(SMC),and winter wheat yield to water and nitrogen rates.The four nitrogen rates were N1(360 kg ha^(-1) pure N),N2(300 kg ha^(-1) pure N),N3(240 kg ha^(-1) pure N),and N4(180 kg ha^(-1) pure N),respectively,and the three irrigation quotas were W1(120 mm),W2(90 mm),and W3(60 mm),respectively.Results showed that the determinate growth function generally performed well in simulating the temporal dynamics of grain weight(0.989<R^(2)<0.999,where R2 is the determination coefficient).The occurrence time of maximum filling rate(T_(max))and active grain-filling period(AGP)increased with the increase in the water or nitrogen rate,whereas the average grain-filling rate(G_(mean))had a decreasing trend.The final 1,000-grain weight(FTGW)increased and then decreased with the increase in the nitrogen rates and increased with the increase in the irrigation rates.The GPS and SMC had a highly significant quadratic polynomial relationship with grain weight and days after anthesis.Nitrogen,irrigation,and year significantly affected the T_(max),AGP,G_(mean),and FTGW.Particularly,the AGP and FTGW were insignificantly different between high seedbed(HLSC-H)and low seedbed(HLSC-L)across the water and nitrogen levels.Moreover,the moderate water and nitrogen supply was more beneficial for grain yield,as well as for spike number and grain number per hectare.The principal component analysis indicated that combining 240-300 kg N ha^(-1) and 90^(-1)20 mm irrigation quota could improve grain-filling efficiency and yield for the HLSC-cultivated winter wheat. 展开更多
关键词 high-low seedbed cultivation water and nitrogen grain filling determinate growth equation wheat yield
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Strawberry (Fragaria spp.): Cultivation, Production, Consumption, and Marketing in Cameroon
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作者 Djeuani Astride Carole Moutamal Djem Rose Theophine Derricka +21 位作者 Mbouobda Hermann Désiré Abdoulaye Souaibou Meliga Essimi Célestine Bouopda Nono Joël Anafack Donasson Dioril Messouang Bernard Didier Ndongo III Boris Charlen Kaffo Emmanuel Kamga Fossouo Anselme Xavier Tiki Antoine Marie Kevin Nyimiebolo Bengono Audrey Maguy Manuela Diobe Motassy Adounga Samuel Brice Amama Amama Benjamin Nshanji Jones Panguepko Fendju Christophe Nzie Oussena Nguetrapouna Issofa Mpon Ikoyin Linda NKouéya Christelle Ladone Amang Amang A. Ziem Niemenak Nicolas 《Agricultural Sciences》 2024年第4期449-471,共23页
Strawberry (Fragaria spp.) is one of the most important fruits classified as exotic fruits imported into Cameroon. To have an inventory of its cultivation in Cameroon, a survey study was carried out among eight farms ... Strawberry (Fragaria spp.) is one of the most important fruits classified as exotic fruits imported into Cameroon. To have an inventory of its cultivation in Cameroon, a survey study was carried out among eight farms of Fragaria spp. from January 2021 to February 2022. The plant was introduced in Cameroon in 2018. There are 13 varieties of Fragaria spp. currently cultivated. Among these 13 varieties, eleven are hybrids of Fragaria x ananassa (“Amiga”, “Amine”, “Camarosa”, “Chandler”, “Charlotte”, “Elsanta”, “Gariguette”, “Madame Moutot”, “Ostara”, “Ruby gem” and “San Andreas”), and two of the hybrids of Fragaria vesca (“Maestro” and “Mara des bois”). The cropping system, irrigation system, and type of fertilizers applied differ from one strawberry farm to another. Biofertilizers (such as mycorrhizal), inorganic and organic fertilizers are actually used to improve production. The potential annual production of strawberries from January 2021 to February 2022, estimated based on the survey data, was 21.216 tons for all growers. Among these eight production farms, the Lolodorf BIO Farm presents 6000 kg (six tons) of strawberries and 100,000 stolons (seedlings) produced, from seven varieties of Fragaria spp. cultivated, with 6 varieties which are hybrids variety Fragaria x ananassa (“Amiga”, “Amine”, “Chandler”, “Gariguette”, “Madame Moutot”, and “Ruby gem”), and one which is a hybrid of Fragaria vesca (“Mara des bois”). Certain diseases were also observed and recorded depending on the growing areas. 展开更多
关键词 Fragaria spp. cultivation Technique Attack of Pathogens Annual Production Cameroon
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Cultivation Path of Nursing Undergraduates’Scientific Research and Innovation Ability
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作者 Guanying Yang Yuan Zhao 《Journal of Biosciences and Medicines》 2024年第5期202-212,共11页
Objective: The cultivation of the innovation ability and scientific research is one of the nursing learning objectives for undergraduate students. To explore the method and effect of training system of scientific rese... Objective: The cultivation of the innovation ability and scientific research is one of the nursing learning objectives for undergraduate students. To explore the method and effect of training system of scientific research innovation ability of nursing undergraduates based on “3332”. Methods: Three course learning modules are constructed: stage-based course learning module, systematic project practice training module and comprehensive practice training module. A practical training platform for scientific research innovation projects is built, and undergraduate scientific research innovation ability training is carried out from both in-class and out-of-class lines. Results: Since 2017, the students have obtained 7 national innovation and entrepreneurship training programs, 52 university-level undergraduate scientific research projects, published more than 10 academic papers, and obtained 2 patent authorization. Conclusions: The training system of scientific research innovation ability of nursing undergraduates based on “3332” is conducive to the development of scientific research innovation ability of nursing students, and to cultivate nursing talents who can adapt to the development of the new era and have better post competence. 展开更多
关键词 Nursing Undergraduates Scientific Research Innovation Ability Learning Module cultivation Path
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The response of roots and the rhizosphere environment to integrative cultivation practices in paddy rice
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作者 Hanzhu Gu Xian Wang +10 位作者 Minhao Zhang Wenjiang Jing Hao Wu Zhilin Xiao Weiyang Zhang Junfei Gu Lijun Liu Zhiqin Wang Jianhua Zhang Jianchang Yang Hao Zhang 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第6期1879-1896,共18页
Integrative cultivation practices(ICPs)are essential for enhancing cereal yield and resource use efficiency.However,the effects of ICP on the rhizosphere environment and roots of paddy rice are still poorly understood... Integrative cultivation practices(ICPs)are essential for enhancing cereal yield and resource use efficiency.However,the effects of ICP on the rhizosphere environment and roots of paddy rice are still poorly understood.In this study,four rice varieties were produced in the field.Each variety was treated with six different cultivation techniques,including zero nitrogen application(0 N),local farmers’practice(LFP),nitrogen reduction(NR),and three progressive ICP techniques comprised of enhanced fertilizer N practice and increased plant density(ICP1),a treatment similar to ICP1 but with alternate wetting and moderate drying instead of continuous flooding(ICP2),and the same practices as ICP2 with the application of organic fertilizer(ICP3).The ICPs had greater grain production and nitrogen use efficiency than the other three methods.Root length,dry weight,root diameter,activity of root oxidation,root bleeding rate,zeatin and zeatin riboside compositions,and total organic acids in root exudates were elevated with the introduction of the successive cultivation practices.ICPs enhanced nitrate nitrogen,the activities of urease and invertase,and the diversity of microbes(bacteria)in rhizosphere and non-rhizosphere soil,while reducing the ammonium nitrogen content.The nutrient contents(ammonium nitrogen,total nitrogen,total potassium,total phosphorus,nitrate,and available phosphorus)and urease activity in rhizosphere soil were reduced in all treatments in comparison with the non-rhizosphere soil,but the invertase activity and bacterial diversity were greater.The main root morphology and physiology,and the ammonium nitrogen contents in rhizosphere soil at the primary stages were closely correlated with grain yield and internal nitrogen use efficiency.These findings suggest that the coordinated enhancement of the root system and the environment of the rhizosphere under integrative cultivation approaches may lead to higher rice production. 展开更多
关键词 rice(Oryza sativa L.) nitrogen use efficiency grain yield integrative cultivation practices ROOTS
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Detection of Bisphenol A (BPA) in Plastic Bottles Using Vertical Cultivation at Various Temperatures
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作者 Karwan Alkaradaghi Tara Ali +2 位作者 Nadhir Al-Ansari Polla Khanaqa Jan Laue 《Journal of Environmental Protection》 2024年第6期656-671,共16页
Polycarbonate plastics containing bisphenol A (BPA) used to manufacture drinking water bottles. Kurdistan region in northern Iraq is a developed area with increased pollution from plastic bottles. Trace amounts of BPA... Polycarbonate plastics containing bisphenol A (BPA) used to manufacture drinking water bottles. Kurdistan region in northern Iraq is a developed area with increased pollution from plastic bottles. Trace amounts of BPA have been detected in bottled water samples. The absorption of BPA was measured with HPLC using a vertical cultivation system with Bulbs of the Allium Cepa plant planted in these plastic bottles with monitored growth. Vertical cultivation was found to have a low level of BPA in the plant cells, making it a safe cultivation method under specific climate conditions. The mean concentration of BPA in vertical cultivation is 0.19 ug/ml (3.8 ng for a 20 uL injection), and the Limit of Quantification (LOQ) is 0.63 ug/ml (12.7 ng for 20 uL injection). While Scanning Electron Microscope (SEM) shows that the concentrations are relatively low in water samples stored at room temperature compared to those exposed to direct sunlight (40°C) and water bottle samples stored at (-4°C), The correlation coefficients were found to be good (0.9992). SEM is used for plastic bottle samples stored at different temperatures. The images identify compound decay and explore the morphology of BPA in manufactured plastic materials. 展开更多
关键词 Vertical cultivation ALLIUM Bisphenol A Plastic Bottles Scanning Electron Microscope (SEM)
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Determinants of Tobacco Cultivation and the Associated Impacts of Adoption in Hurungwe District, Zimbabwe
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作者 Spencer Sibanda Satoshi Tsuyuki 《Agricultural Sciences》 2024年第4期505-531,共27页
Tobacco is an essential cash crop in Zimbabwe and a strategic livelihood option for hundreds of thousands of rural households. However, the crop is linked to negative environmental, economic, and social impacts. The e... Tobacco is an essential cash crop in Zimbabwe and a strategic livelihood option for hundreds of thousands of rural households. However, the crop is linked to negative environmental, economic, and social impacts. The existing studies on tobacco cultivation in Zimbabwe present contradictory findings on the determinants and impacts of adoption, leaving unanswered questions about the crop’s sustainability impact in the country. This article investigates the determinants of smallholder farmers’ decisions to grow tobacco and the associated impacts of adoption. Random and purposive sampling were used to select 273 household surveys, including tobacco and non-tobacco smallholder farmers, and 56 expert interviews to answer the research questions. We employed regression models alongside expert interviews and document analysis to identify the determinants influencing the decision-making process of smallholder farmers in Zimbabwe regarding tobacco cultivation. Additionally, our investigation aimed to elucidate the perceived impacts associated with the adoption of this agricultural practice. The regression analysis indicated that the farmer’s age, education level, farming experience, family size, household income, and perceived high farm profitability are significant drivers of tobacco adoption. We also discovered divergent and convergent perceptions of the critical impacts of tobacco cultivation. The study highlights the need for proactive multi-stakeholder collaboration and sustainable financial arrangements to address the negative impacts of tobacco production. As the primary stakeholder responsible for regulating and promoting agricultural activities, the Zimbabwean government should provide meaningful financial support, increase access to credit, and ensure better market facilities for alternative crops to reduce the over-dependence on tobacco. 展开更多
关键词 Tobacco cultivation Determinants of Adoption Sustainability Impacts Economic Livelihood Stakeholder Perceptions
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Rotating tank experiments for the study of geophysical fluid dynamics
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作者 Changming DONG Xiaojie LU +6 位作者 Yuli LIU Guoqing HAN Minghan FU Qian CAO Yang ZHANG Xu CHEN Yeping YUAN 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2024年第5期1385-1398,共14页
Geophysical fluid dynamics(GFD)is an interdisciplinary field that studies the large-scale motion of fluids in the natural world.With a wide range of applications such as weather forecasts and climate prediction,GFD em... Geophysical fluid dynamics(GFD)is an interdisciplinary field that studies the large-scale motion of fluids in the natural world.With a wide range of applications such as weather forecasts and climate prediction,GFD employs various research approaches including in-situ observations,satellite measurements,numerical simulations,theoretical analysis,artificial intelligence,and physical model experiments in laboratory.Among these approaches,rotating tank experiments provide a valuable tool for simulating naturally-occurring fluid motions in laboratories.With proportional scaling and proper techniques,scientists can reproduce multi-scale physical processes of stratified fluids in the rotation system,which allows for the simulation of essential characteristics of fluid motions in the atmosphere and oceans.In this review,rotating tanks of various scales in the world are introduced,as these tanks have been actively used to explore fundamental scientific questions in ocean and atmosphere dynamics.To illustrate the GFD experiments,three representative cases are presented to demonstrate the frontier achievements in the the GFD study by using rotating tank experiments:mesoscale eddies in the ocean,convection processes,and plume dynamics.Detailed references for the experimental procedures are provided.Future studies are encouraged to further explore the utilization of rotating tanks with improvements in experimental design and integration of other research methods.This is a promising direction of GFD to help enhance our understanding of the complex nature of fluid motions in the natural world and to address the challenges posed by global environmental changes. 展开更多
关键词 laboratory experiment rotating tank geophysical fluid dynamics(GFD)
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Flume experiments to study fine-grain migration and its impact on slope stability
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作者 WANG Baoliang WANG Quanwei +2 位作者 LI Yong YAO Zhenguo WANG Hongfei 《Journal of Mountain Science》 SCIE CSCD 2024年第10期3552-3566,共15页
Fine grains migration is a primary cause of landslides and debris flows.This study investigates the effect of fine-grain migration on slope failure through flume experiments,focusing on the spatiotemporal characterist... Fine grains migration is a primary cause of landslides and debris flows.This study investigates the effect of fine-grain migration on slope failure through flume experiments,focusing on the spatiotemporal characteristics and mechanisms of slope stability.A series of artificial rainfall flume experiments with varying rainfall intensities and slopes were conducted using soil samples collected from Wei Jia Gully.The experiments monitored pore-water pressure,grain migration,and failure sequences.Grain-size distribution parameters(μand Dc)were analyzed to understand the migration path and accumulation of fine grains.The experiments reveal that fine-grain migration significantly alters soil structure,leading to random blockage and interconnection of internal pore channels.These changes result in fluctuating pore-water pressure distributions and uneven fine-grain accumulation,critical factors in slope stability.Slope failures occur randomly and intermittently,influenced by fine-grain content in runoff and resulting pore-water pressure variations.This study highlights that fine-grain migration plays a vital role in slope stability,with significant implications for predicting and mitigating slope failures.The stochastic nature of fine-grain migration and its impact on soil properties should be incorporated into predictive models to enhance their accuracy and reliability. 展开更多
关键词 Fine-grain migration Slope stability Pore-water pressure Artificial rainfall Soil structure Flume experiments
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Laboratory Experiments Do Not Support the Greenhouse Effect as Applicable to CO2
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作者 Michael D. Nelson 《International Journal of Geosciences》 CAS 2024年第10期809-839,共31页
The analysis of Greenhouse Effect experiments in the public domain indicated that the lab tests were primarily centered around illustrating the mechanics of conventional greenhouses. They used high-energy visible ligh... The analysis of Greenhouse Effect experiments in the public domain indicated that the lab tests were primarily centered around illustrating the mechanics of conventional greenhouses. They used high-energy visible light (such as sunlight), rather than addressing the Greenhouse Effect, which involves low-energy infrared radiation emitted by the Earth’s surface. Studies with argon, a non-greenhouse gas with similar density to CO2, showed thermal heat transfer as the dominant factor in the temperature profiles, with radiation absorption being undetected. The same conclusion was drawn by another study, which measured infrared back radiation. Experiments using exaggerated CO2 concentrations inadvertently illustrated the principle of the Popper Falsification Test by disproving the Greenhouse Effect applicable to CO2 within the troposphere. A straightforward kitchen test showed that a microwave oven cannot be used as a model for the Greenhouse Effect. 展开更多
关键词 Laboratory Experiment Climate Change Greenhouse Effect CO2
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Strategic insights into the cultivation of pancreatic cancer organoids from endoscopic ultrasonography-guided biopsy tissue
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作者 Jia-Li Yang Jun-Feng Zhang +4 位作者 Jian-You Gu Mei Gao Ming-You Zheng Shi-Xiang Guo Tao Zhang 《World Journal of Gastroenterology》 SCIE CAS 2024年第42期4532-4543,共12页
BACKGROUND The frequent suboptimal efficacy of endoscopic ultrasound-guided fine-needle biopsy(EUS-FNB)to culture pancreatic cancer(PC)organoids(PCOs)poses a major challenge in the advancement of personalized medicine... BACKGROUND The frequent suboptimal efficacy of endoscopic ultrasound-guided fine-needle biopsy(EUS-FNB)to culture pancreatic cancer(PC)organoids(PCOs)poses a major challenge in the advancement of personalized medicine for advanced PC.AIM To explore how to obtain appropriate puncture tissues from EUS-FNB and optimize the strategy for efficiently constructing PCOs,providing an efficient tool for the advancement of personalized medicine.METHODS Patients who underwent EUS-FNB for the diagnosis of PC tissue were prospectively enrolled.We refined the endoscopic biopsy procedures and organoid cultivation techniques.All tissue specimens verified by on-site pathological assessment were cultured in a semi-suspended medium in a microfluidic environment.We assessed differences in PCOs cultured beyond and below five generations examining patient demographics,specimen and organoid attributes,and the sensitivity of organoids to a panel of clinical drugs through cell viability assays.RESULTS In this study,16 patients with PC were recruited,one sample was excluded because onsite cytopathology showed no tumor cells.Successful organoid generation occurred in 93.3%(14 of 15)of the EUS-FNB specimens,with 60%(9 of 15)sustaining over five generations.Among these patients,those with a history of diabetes,familial cancer,or larger tumors exhibited enhanced PCO expandability.The key factors influencing longterm PCOs expansion included initial needle sample quality(P=0.005),rapid initiation of organoid culture postisolation(P≤0.001),and high organoid activity(P=0.031).Drug sensitivity analysis revealed a partial response in two patients following therapeutic intervention and surgery and stable disease in four patients,indicating a moderate correlation between organoid response and clinical outcomes.CONCLUSION Optimal initial needle sampling,rapid and precise biopsy sample processing,process isolated samples as soon as possible,and sufficient cellular material are crucial for successful cultivating PCOs.High organoid activity is an important factor in maintaining their long-term expansion,which is essential for shortening the time of drug sensitivity analysis and is the basis of PC research. 展开更多
关键词 Endoscopic ultrasound-guided fine-needle biopsy Pancreatic cancer organoid Puncture technique cultivation optimization strategy Drug screening
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Technique of Earthworms Restoring Soil in Greenhouse Cultivation
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作者 Yanjiao LI Jiafei SU +7 位作者 Zhiu ZHANG Guang QI Jianhua CHEN Lixuan KOU Limin WANG Wenxian LIU Junyi ZHANG Libing QIU 《Asian Agricultural Research》 2024年第1期40-43,共4页
The production environment of greenhouse cultivation is relatively closed,the multiple cropping index is high,the management of fertilizationwatering and pesticideapplication isblindtosomeextent,andthe phenomenonofcon... The production environment of greenhouse cultivation is relatively closed,the multiple cropping index is high,the management of fertilizationwatering and pesticideapplication isblindtosomeextent,andthe phenomenonofcontinuous cropping isalsocommonSoilquali-ty affects the sustainable development of greenhouse cultivation.Earthworm is a ubiquitous invertebrate organism in soil,an important part of soil system,a link between terrestrial organisms and soil organisms,an important link in the small cycle of soil material organisms,and plays an important role in maintaining the structure and function of soil ecosystem.Different ecotypes of earthworms are closely related to their habi-tats(soil layers)and food resource preferences,and then affect their ecological functions.The principle of earthworm regulating soil function is essentially the close connection and interaction between earthworm and soil microorganism.Using different ecotypes of earthworms and bio-logical agents to carry out combined remediation of greenhouse cultivation soil is a technical model to realize sustainable development of green-house cultivation. 展开更多
关键词 Earthworms Greenhouse cultivation Soil remediation Biological agent
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Predicting the probability distribution of Martian rocks mechanical property based on microscale rock mechanical experiments and accurate grain-based modeling
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作者 Shuohui Yin Yingjie Wang Jingang Liu 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第9期1327-1339,共13页
The exploration of Mars would heavily rely on Martian rocks mechanics and engineering technology.As the mechanical property of Martian rocks is uncertain,it is of utmost importance to predict the probability distribut... The exploration of Mars would heavily rely on Martian rocks mechanics and engineering technology.As the mechanical property of Martian rocks is uncertain,it is of utmost importance to predict the probability distribution of Martian rocks mechanical property for the success of Mars exploration.In this paper,a fast and accurate probability distribution method for predicting the macroscale elastic modulus of Martian rocks was proposed by integrating the microscale rock mechanical experiments(micro-RME),accurate grain-based modeling(AGBM)and upscaling methods based on reliability principles.Firstly,the microstructure of NWA12564 Martian sample and elastic modulus of each mineral were obtained by micro-RME with TESCAN integrated mineral analyzer(TIMA)and nanoindentation.The best probability distribution function of the minerals was determined by Kolmogorov-Smirnov(K-S)test.Secondly,based on best distribution function of each mineral,the Monte Carlo simulations(MCS)and upscaling methods were implemented to obtain the probability distribution of upscaled elastic modulus.Thirdly,the correlation between the upscaled elastic modulus and macroscale elastic modulus obtained by AGBM was established.The accurate probability distribution of the macroscale elastic modulus was obtained by this correlation relationship.The proposed method can predict the probability distribution of Martian rocks mechanical property with any size and shape samples. 展开更多
关键词 Probability distribution Martian rocks Microscale rock mechanic experiment Nanoindentation Accurate grain-based modeling
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Ballistic limit velocity of small caliber projectiles against SS400 steel plates:Live fire experiments and empirical models
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作者 Jong-Hwan Kim Seungwon Baik +1 位作者 Jirui Fu Joon-Hyuk Park 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第11期22-34,共13页
This study presents the ballistic limit velocity of small caliber projectiles against SS400 steel plate derived from live-fire ballistic experiments. Four different small caliber projectiles were tested against SS400 ... This study presents the ballistic limit velocity of small caliber projectiles against SS400 steel plate derived from live-fire ballistic experiments. Four different small caliber projectiles were tested against SS400 steel plates of 9 mm, 10 mm, and 12 mm thicknesses. The ballistic limit velocity was calculated using two standard methods, MIL-STD-662F and NIJ-STD-0101.06, and additionally using a support vector machine algorithm. The results show a linear relationship between the plate thickness and ballistic limit velocity. Further, the relative penetration performance among five different small caliber projectiles was analyzed using the Penetration Performance Ratio(PPR) introduced in this study, which suggests the potential of PPR to predict the ballistic limit velocity of other untested materials and/or different projectiles. 展开更多
关键词 Live fire ballistic experiment SS400 Ballistic limit velocity Small caliber projectile
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High Yield Cultivation and Pest Control Technology of Cashew
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作者 Li ZHAO Weijian HUANG +1 位作者 Zhongrun ZHANG Haijie HUANG 《Plant Diseases and Pests》 2024年第3期21-22,共2页
In order to enhance the yield and quality of cashew,it is essential to implement high-yield cultivation techniques effectively throughout the production process.Additionally,pest control measures should be employed to... In order to enhance the yield and quality of cashew,it is essential to implement high-yield cultivation techniques effectively throughout the production process.Additionally,pest control measures should be employed to provide technical support for the industrialized development of cashew. 展开更多
关键词 CASHEW High yield cultivation Pest control technology
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Rice Cultivation under Film Mulching Can Improve Soil Environment and Be Beneficial for Rice Production in China
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作者 ZHANG Youliang ZHU Kaican +1 位作者 TANG Yongqi FENG Shaoyuan 《Rice science》 SCIE CSCD 2024年第5期545-555,共11页
Rice cultivation under film mulching is an integrated management technology that can conserve water, increase soil temperature, improve yield, and enhance water and nitrogen use efficiencies. Despite these advantages,... Rice cultivation under film mulching is an integrated management technology that can conserve water, increase soil temperature, improve yield, and enhance water and nitrogen use efficiencies. Despite these advantages, the system does have its drawbacks, such as soil organic matter reduction and microplastic pollution, which impede the widespread adoption of film mulching cultivation in China. Nonetheless, the advent of degradable film, controlled-release fertilizer, organic fertilizer, and film mulching machinery is promoting the development of rice film mulching cultivation. This review outlines the impact of rice cultivation under film mulching on soil moisture, soil temperature, soil fertility, greenhouse gas emissions, weed control, and disease and pest management. It also elucidates the mechanism of changes in rice growth, yield and quality, water use efficiency, and nitrogen use efficiency. This paper incorporates a review of published research articles and discusses some uncertainties and shortcomings associated with rice cultivation under film mulching. Consequently, prospective research directions for the technology of rice film mulching cultivation are outlined, and recommendations for future research into rice cultivation under film mulching are proposed. 展开更多
关键词 nitrogen use efficiency rice cultivation under film mulching soil organic matter yield and quality water use efficiency
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Variety Selection and Green Cultivation Technology of Courtyard Ornamental and Edible Peppers
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作者 Xilu ZHANG Shengying JI +2 位作者 Yinglin YE Xingzhi DING Juan CHEN 《Plant Diseases and Pests》 2024年第3期26-30,共5页
In order to comply with the development trend of the multifunctional use of peppers,we conducted an investigation into the characteristics and features of varieties,potting management techniques,and the methods of ext... In order to comply with the development trend of the multifunctional use of peppers,we conducted an investigation into the characteristics and features of varieties,potting management techniques,and the methods of extending the fruit ornamental period and other aspects of courtyard ornamental and edible peppers.A set of cultivation techniques suitable for courtyard ornamental and edible peppers has been developed,including timely sowing and seedling,nutrient soil preparation,water and fertilizer management,trimming and pruning,preservation of flowers and fruits,green prevention and control of diseases and pests,harvesting,and so on. 展开更多
关键词 Ornamental and edible pepper Courtyard gardening Variety characteristics cultivation technique
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