In this paper,an NMOS output-capacitorless low-dropout regulator(OCL-LDO)featuring dual-loop regulation has been proposed,achieving fast transient response with low power consumption.An event-driven charge pump(CP)loo...In this paper,an NMOS output-capacitorless low-dropout regulator(OCL-LDO)featuring dual-loop regulation has been proposed,achieving fast transient response with low power consumption.An event-driven charge pump(CP)loop with the dynamic strength control(DSC),is proposed in this paper,which overcomes trade-offs inherent in conventional structures.The presented design addresses and resolves the large signal stability issue,which has been previously overlooked in the event-driven charge pump structure.This breakthrough allows for the full exploitation of the charge-pump structure's poten-tial,particularly in enhancing transient recovery.Moreover,a dynamic error amplifier is utilized to attain precise regulation of the steady-state output voltage,leading to favorable static characteristics.A prototype chip has been fabricated in 65 nm CMOS technology.The measurement results show that the proposed OCL-LDO achieves a 410 nA low quiescent current(IQ)and can recover within 30 ns under 200 mA/10 ns loading change.展开更多
The arc regulation method is applied to the high-current ion source for high-power hydrogen ion beam extraction for the first time. The characteristics of the arc and beam, including the probe ion saturation current, ...The arc regulation method is applied to the high-current ion source for high-power hydrogen ion beam extraction for the first time. The characteristics of the arc and beam, including the probe ion saturation current, the arc power and the beam current, are studied with feedback control. The results show that the arc regulation method can be successfully applied to ion beam extraction. This lays a sound foundation for the testing of a new ion source and the operation of a conditioned ion source for neutral beam injector devices.展开更多
BACKGROUND Acute recurrent pancreatitis(ARP)is characterized by episodes of acute pancreatitis in an otherwise normal gland.When no cause of ARP is identifiable,the diagnosis of"idiopathic"ARP is given.Mutat...BACKGROUND Acute recurrent pancreatitis(ARP)is characterized by episodes of acute pancreatitis in an otherwise normal gland.When no cause of ARP is identifiable,the diagnosis of"idiopathic"ARP is given.Mutations in the cystic fibrosis transmembrane conductance regulator(CFTR)gene increase the risk of ARP by 3-to 4-times compared to the general population,while cystic fibrosis(CF)patients present with a 40-to 80-times higher risk of developing pancreatitis.CASE SUMMARY In non-classical CF or CFTR-related disorders,CFTR functional tests can help to ensure a proper diagnosis.We applied an individualized combination of standardized and new CFTR functional bioassays for a patient referred to the Verona CF Center for evaluation after several episodes of acute pancreatitis.The CFTR genotype was G542X+/-with IVS8Tn:T7/9 polymorphism.The sweat(Cl-)values were borderline.Intestinal current measurements were performed according to the European Cystic Fibrosis Society Standardized Operating Procedure.Recent nasal surgery for deviated septum did not allow for nasal potential difference measurements.Lung function and sputum cultures were normal;azoospermia was excluded.Pancreas divisum was excluded by imaging but hypoplasia of the left hepatic lobe was detected.Innovative tests applied in this case include sweat rate measurement by image analysis,CFTR function in monocytes evaluated using a membrane potential-sensitive fluorescent probe,and the intestinal organoids forskolin-induced swelling assay.CONCLUSION Combination of innovative CFTR functional assays might support a controversial diagnosis when CFTR-related disorders and/or non-classical CF are suspected.展开更多
An ultra-low quiescent current low-dropout regulator with small output voltage variations and improved load regulation is presented in this paper. It makes use of dynamically-biased shunt feedback as the buffer stage ...An ultra-low quiescent current low-dropout regulator with small output voltage variations and improved load regulation is presented in this paper. It makes use of dynamically-biased shunt feedback as the buffer stage and the LDO regulator can be stable for all load conditions. The proposed structure also employs a momentarily current-boosting circuit to reduce the output voltage to the normal value when output is switched from full load to no load. The whole circuit is designed in a 0.18 μm CMOS technology with a quiescent current of 550 nA. The maximum output voltage variation is less than 20 mV when used with 1 μF external capacitor.展开更多
Recent bathymetric changes in the Changjiang Estuary under the influence of artificial regulation engineerings and basin reservoirs have been analyzed based on the maritime charts since 1997 and recent fieldworks. The...Recent bathymetric changes in the Changjiang Estuary under the influence of artificial regulation engineerings and basin reservoirs have been analyzed based on the maritime charts since 1997 and recent fieldworks. The results indicate a slight erosion of the channels in the upper and middle estuary, continuing deposition and seaward move of the mouth bar crest and intensifying erosion at the nearshore seabed. It is noteworthy that the morphological evolution caused by intensive human activities dominates over the changes from nature process. First, the riverbes are eroded overall in the South Branch (SB), the South Channel (SC) and the upper and middle reaches of the North Channel (NC). The nearshore seabed outside the river mouth is being eroded slightly, which is attributed to the declining sediment supply from the Changjiang Basin due to the construction of the Three Gorges Dam upstream. The sediment above the seabed is very active and coarsened, meanwhile, sand waves are becoming more distinct. Second, a deposition occurs in the North Brach (NB), the mouth of the NC, the mouth bars of the North Passage (NP) and the South Passage (SP) and especially the main channel of the NP, where it shows a massive siltation after the deep waterway project. The reasons for the recent changes are not only the dynamic structure in estuarine mouth bars, but also the supply of sediment resuspension in a local and offshore area. Meanwhile, the severe erosion and siltation in some reaches is related to the construction of estuarine engineerings. It is indicated that the Changjiang Estuary is gradually self-adjusted and adapting to the varying natural factors and intensive human activities. The study on the mechanism of self-regulation of the recent bathymetric changes in the Changjiang Estuary has important and practical significance.展开更多
Improving the temperature stability and widening the constant current range are two important problems to be solved in the application of the current regulators. This paper introduces a modular approach for the design...Improving the temperature stability and widening the constant current range are two important problems to be solved in the application of the current regulators. This paper introduces a modular approach for the design of the current regulator with a very wide current range. The test results show that their output current ranges from 0.1A to 8A, with its current temperature coefficient as low as 10-4/℃ to 10-5/℃ and limiting voltage lower than 0.4V.展开更多
Coupled inductor is one appealing technology to improve transient response and reduce output decoupling significantly in interleaved multi-phase voltage regulators (VRs). One known problem is that there is no mature s...Coupled inductor is one appealing technology to improve transient response and reduce output decoupling significantly in interleaved multi-phase voltage regulators (VRs). One known problem is that there is no mature solution yet to sense the individual phase current accurately in a lossless way for couple inductor based VRs design. This will impact VR some normal function in one phase mode. This paper proposes a new solution to this problem and simulation is conducted to verify effectiveness of the proposal.展开更多
The speed regulation problem with only speed measurement is investigated in this paper for a permanent magnet direct current(DC)motor driven by a buck converter.By lumping all unknown matched/unmatched disturbances an...The speed regulation problem with only speed measurement is investigated in this paper for a permanent magnet direct current(DC)motor driven by a buck converter.By lumping all unknown matched/unmatched disturbances and uncertainties together,the traditional active disturbance rejection control(ADRC)approach provides an intuitive solution for the problem under consideration.However,for such a higher-order disturbed system,the increase of poles for the extended state observer(ESO)therein will lead to drastically growth of observer gains,which causes severe noise amplification.This paper aims to propose a new model-based disturbance rejection controller for the converter-driven DC motor system using output-feedback.Instead of estimating lumped disturbances directly,a new observer is constructed to estimate the desired steady state of control signal as well as errors between the real states and their desired steady-state responses.Thereafter,a controller with only speed measurement is proposed by utilizing the estimates.The performance of the proposed method is tested through experiments on dSPACE.It is further shown via numerical calculations and experimental results that the poles of the observer within the proposed control approach can be largely increased without significantly increasing magnitude of the observer gains.展开更多
Frequency regulation of voltage source converter-based multi-terminal high-voltage direct current(VSC-MTDC)system with offshore wind farms enhances the frequency stability by compensating the power for a disturbed AC ...Frequency regulation of voltage source converter-based multi-terminal high-voltage direct current(VSC-MTDC)system with offshore wind farms enhances the frequency stability by compensating the power for a disturbed AC system.However,it is difficult to reasonably allocate frequency-regulation resources due to a lack of coordination mechanisms between wind farms and the MTDC system.Moreover,it is difficult for the frequency control of the wind farms to manage changes in wind speed;and the risk of wind-turbine stalls is high.Thus,based on the kinetic energy of wind turbines and the power margin of the converters,the frequency-regulation capability of wind turbines is evaluated,and a dynamic frequency-support scheme considering the real-time frequency-support capability of the wind turbines and system frequency evolution is proposed to improve the frequency-support performance.A power adaptation technique at variable wind speeds is developed;the active power in the frequency-support stage and restoration stage is switched according to the wind speed.A hierarchical zoning frequency-regulation scheme is designed to use the frequency-regulation resources of different links in the MTDC system with wind farms.The simulation results show that the novel frequency-regulation strategy maintains frequency stability with wind-speed changes and avoids multiple frequency dips.展开更多
该文针对多源时变干扰影响的双三相永磁同步电机系统,研究其基波平面内的调速控制问题和谐波平面内的谐波电流抑制问题。首先,在基波平面采用非串级控制结构,通过构造广义比例积分观测器(generalized proportional integral observer,GP...该文针对多源时变干扰影响的双三相永磁同步电机系统,研究其基波平面内的调速控制问题和谐波平面内的谐波电流抑制问题。首先,在基波平面采用非串级控制结构,通过构造广义比例积分观测器(generalized proportional integral observer,GPIO)估计转速环的多源快变干扰;然后,针对q轴电流的过流保护问题,在传统比例微分反馈控制器的基础上利用障碍函数设计思想,结合干扰估计信息,得到基于GPIO的电流约束复合控制器;其次,在谐波平面,通过设计2个GPIO精准估计电流环的多源快变干扰,并与比例反馈控制器结合形成复合控制器来抑制2个电流环中的谐波电流。最后,给出严谨的稳定性分析,并通过对比实验验证所提方法的有效性。展开更多
基金supported by the National Natural Science Foundation of China under Grant 62274189the Natural Science Foundation of Guangdong Province,China,under Grant 2022A1515011054the Key Area R&D Program of Guangdong Province under Grant 2022B0701180001.
文摘In this paper,an NMOS output-capacitorless low-dropout regulator(OCL-LDO)featuring dual-loop regulation has been proposed,achieving fast transient response with low power consumption.An event-driven charge pump(CP)loop with the dynamic strength control(DSC),is proposed in this paper,which overcomes trade-offs inherent in conventional structures.The presented design addresses and resolves the large signal stability issue,which has been previously overlooked in the event-driven charge pump structure.This breakthrough allows for the full exploitation of the charge-pump structure's poten-tial,particularly in enhancing transient recovery.Moreover,a dynamic error amplifier is utilized to attain precise regulation of the steady-state output voltage,leading to favorable static characteristics.A prototype chip has been fabricated in 65 nm CMOS technology.The measurement results show that the proposed OCL-LDO achieves a 410 nA low quiescent current(IQ)and can recover within 30 ns under 200 mA/10 ns loading change.
基金supported by the National Magnetic Confinement Fusion Science Program of China(No.2013GB101000)partly supported by National Natural Science Foundation of China(No.11075183)the Knowledge Innovation Program of the Chinese Academy of Sciences(Study of the physical characteristics of arc power feedback control for the high current ion source)
文摘The arc regulation method is applied to the high-current ion source for high-power hydrogen ion beam extraction for the first time. The characteristics of the arc and beam, including the probe ion saturation current, the arc power and the beam current, are studied with feedback control. The results show that the arc regulation method can be successfully applied to ion beam extraction. This lays a sound foundation for the testing of a new ion source and the operation of a conditioned ion source for neutral beam injector devices.
基金Supported by Italian CF Research Foundation with the contributions of Delegazione FFC di Palermo e di Vittoria Ragusa Catania 2,No.FFC grants No.4/2013Delegazione FFC di Treviso Montebelluna La Bottega delle Donne,No.3/2014+3 种基金Delegazione FFC di Belluno,No.7/2016Delegazione FFC di Taranto Massafra,Cosenza sud,della Valpolicella,Guadagnin SRL,No.6/2018Delegazione FFC di Tradate Gallarate,No.13/2018CFFT-USA and Lega Italiana Fibrosi Cistica-Associazione Veneta ONLUS
文摘BACKGROUND Acute recurrent pancreatitis(ARP)is characterized by episodes of acute pancreatitis in an otherwise normal gland.When no cause of ARP is identifiable,the diagnosis of"idiopathic"ARP is given.Mutations in the cystic fibrosis transmembrane conductance regulator(CFTR)gene increase the risk of ARP by 3-to 4-times compared to the general population,while cystic fibrosis(CF)patients present with a 40-to 80-times higher risk of developing pancreatitis.CASE SUMMARY In non-classical CF or CFTR-related disorders,CFTR functional tests can help to ensure a proper diagnosis.We applied an individualized combination of standardized and new CFTR functional bioassays for a patient referred to the Verona CF Center for evaluation after several episodes of acute pancreatitis.The CFTR genotype was G542X+/-with IVS8Tn:T7/9 polymorphism.The sweat(Cl-)values were borderline.Intestinal current measurements were performed according to the European Cystic Fibrosis Society Standardized Operating Procedure.Recent nasal surgery for deviated septum did not allow for nasal potential difference measurements.Lung function and sputum cultures were normal;azoospermia was excluded.Pancreas divisum was excluded by imaging but hypoplasia of the left hepatic lobe was detected.Innovative tests applied in this case include sweat rate measurement by image analysis,CFTR function in monocytes evaluated using a membrane potential-sensitive fluorescent probe,and the intestinal organoids forskolin-induced swelling assay.CONCLUSION Combination of innovative CFTR functional assays might support a controversial diagnosis when CFTR-related disorders and/or non-classical CF are suspected.
文摘An ultra-low quiescent current low-dropout regulator with small output voltage variations and improved load regulation is presented in this paper. It makes use of dynamically-biased shunt feedback as the buffer stage and the LDO regulator can be stable for all load conditions. The proposed structure also employs a momentarily current-boosting circuit to reduce the output voltage to the normal value when output is switched from full load to no load. The whole circuit is designed in a 0.18 μm CMOS technology with a quiescent current of 550 nA. The maximum output voltage variation is less than 20 mV when used with 1 μF external capacitor.
基金The National Natural Science Foundation of China under contract Nos 51479074 and 41340044the Special Key Program of the Ministry of Science and Technology of China under contract No.2013FY112000
文摘Recent bathymetric changes in the Changjiang Estuary under the influence of artificial regulation engineerings and basin reservoirs have been analyzed based on the maritime charts since 1997 and recent fieldworks. The results indicate a slight erosion of the channels in the upper and middle estuary, continuing deposition and seaward move of the mouth bar crest and intensifying erosion at the nearshore seabed. It is noteworthy that the morphological evolution caused by intensive human activities dominates over the changes from nature process. First, the riverbes are eroded overall in the South Branch (SB), the South Channel (SC) and the upper and middle reaches of the North Channel (NC). The nearshore seabed outside the river mouth is being eroded slightly, which is attributed to the declining sediment supply from the Changjiang Basin due to the construction of the Three Gorges Dam upstream. The sediment above the seabed is very active and coarsened, meanwhile, sand waves are becoming more distinct. Second, a deposition occurs in the North Brach (NB), the mouth of the NC, the mouth bars of the North Passage (NP) and the South Passage (SP) and especially the main channel of the NP, where it shows a massive siltation after the deep waterway project. The reasons for the recent changes are not only the dynamic structure in estuarine mouth bars, but also the supply of sediment resuspension in a local and offshore area. Meanwhile, the severe erosion and siltation in some reaches is related to the construction of estuarine engineerings. It is indicated that the Changjiang Estuary is gradually self-adjusted and adapting to the varying natural factors and intensive human activities. The study on the mechanism of self-regulation of the recent bathymetric changes in the Changjiang Estuary has important and practical significance.
文摘Improving the temperature stability and widening the constant current range are two important problems to be solved in the application of the current regulators. This paper introduces a modular approach for the design of the current regulator with a very wide current range. The test results show that their output current ranges from 0.1A to 8A, with its current temperature coefficient as low as 10-4/℃ to 10-5/℃ and limiting voltage lower than 0.4V.
文摘Coupled inductor is one appealing technology to improve transient response and reduce output decoupling significantly in interleaved multi-phase voltage regulators (VRs). One known problem is that there is no mature solution yet to sense the individual phase current accurately in a lossless way for couple inductor based VRs design. This will impact VR some normal function in one phase mode. This paper proposes a new solution to this problem and simulation is conducted to verify effectiveness of the proposal.
基金supported in part by the Natural Science Foundation of China(61973080,61973081)by the Aviation Key Laboratory of Science and Technology on Aero Electromechanical System Integration(201928069002)the Key R&D Plan of Jiangsu Province(BE2020082-4)。
文摘The speed regulation problem with only speed measurement is investigated in this paper for a permanent magnet direct current(DC)motor driven by a buck converter.By lumping all unknown matched/unmatched disturbances and uncertainties together,the traditional active disturbance rejection control(ADRC)approach provides an intuitive solution for the problem under consideration.However,for such a higher-order disturbed system,the increase of poles for the extended state observer(ESO)therein will lead to drastically growth of observer gains,which causes severe noise amplification.This paper aims to propose a new model-based disturbance rejection controller for the converter-driven DC motor system using output-feedback.Instead of estimating lumped disturbances directly,a new observer is constructed to estimate the desired steady state of control signal as well as errors between the real states and their desired steady-state responses.Thereafter,a controller with only speed measurement is proposed by utilizing the estimates.The performance of the proposed method is tested through experiments on dSPACE.It is further shown via numerical calculations and experimental results that the poles of the observer within the proposed control approach can be largely increased without significantly increasing magnitude of the observer gains.
基金supported by the National Key R&D Program of China(No.2022YFB2402700).
文摘Frequency regulation of voltage source converter-based multi-terminal high-voltage direct current(VSC-MTDC)system with offshore wind farms enhances the frequency stability by compensating the power for a disturbed AC system.However,it is difficult to reasonably allocate frequency-regulation resources due to a lack of coordination mechanisms between wind farms and the MTDC system.Moreover,it is difficult for the frequency control of the wind farms to manage changes in wind speed;and the risk of wind-turbine stalls is high.Thus,based on the kinetic energy of wind turbines and the power margin of the converters,the frequency-regulation capability of wind turbines is evaluated,and a dynamic frequency-support scheme considering the real-time frequency-support capability of the wind turbines and system frequency evolution is proposed to improve the frequency-support performance.A power adaptation technique at variable wind speeds is developed;the active power in the frequency-support stage and restoration stage is switched according to the wind speed.A hierarchical zoning frequency-regulation scheme is designed to use the frequency-regulation resources of different links in the MTDC system with wind farms.The simulation results show that the novel frequency-regulation strategy maintains frequency stability with wind-speed changes and avoids multiple frequency dips.
文摘该文针对多源时变干扰影响的双三相永磁同步电机系统,研究其基波平面内的调速控制问题和谐波平面内的谐波电流抑制问题。首先,在基波平面采用非串级控制结构,通过构造广义比例积分观测器(generalized proportional integral observer,GPIO)估计转速环的多源快变干扰;然后,针对q轴电流的过流保护问题,在传统比例微分反馈控制器的基础上利用障碍函数设计思想,结合干扰估计信息,得到基于GPIO的电流约束复合控制器;其次,在谐波平面,通过设计2个GPIO精准估计电流环的多源快变干扰,并与比例反馈控制器结合形成复合控制器来抑制2个电流环中的谐波电流。最后,给出严谨的稳定性分析,并通过对比实验验证所提方法的有效性。