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Automatic modulation recognition of radio fuzes using a DR2D-based adaptive denoising method and textural feature extraction 被引量:1
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作者 Yangtian Liu Xiaopeng Yan +2 位作者 Qiang Liu Tai An Jian Dai 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第4期328-338,共11页
The identification of intercepted radio fuze modulation types is a prerequisite for decision-making in interference systems.However,the electromagnetic environment of modern battlefields is complex,and the signal-to-n... The identification of intercepted radio fuze modulation types is a prerequisite for decision-making in interference systems.However,the electromagnetic environment of modern battlefields is complex,and the signal-to-noise ratio(SNR)of such environments is usually low,which makes it difficult to implement accurate recognition of radio fuzes.To solve the above problem,a radio fuze automatic modulation recognition(AMR)method for low-SNR environments is proposed.First,an adaptive denoising algorithm based on data rearrangement and the two-dimensional(2D)fast Fourier transform(FFT)(DR2D)is used to reduce the noise of the intercepted radio fuze intermediate frequency(IF)signal.Then,the textural features of the denoised IF signal rearranged data matrix are extracted from the statistical indicator vectors of gray-level cooccurrence matrices(GLCMs),and support vector machines(SVMs)are used for classification.The DR2D-based adaptive denoising algorithm achieves an average correlation coefficient of more than 0.76 for ten fuze types under SNRs of-10 d B and above,which is higher than that of other typical algorithms.The trained SVM classification model achieves an average recognition accuracy of more than 96%on seven modulation types and recognition accuracies of more than 94%on each modulation type under SNRs of-12 d B and above,which represents a good AMR performance of radio fuzes under low SNRs. 展开更多
关键词 Automatic modulation recognition Adaptive denoising data rearrangement and the 2d FFT(dR2d) Radio fuze
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Homological properties of modules characterized by matrices
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作者 张小向 陈建龙 《Journal of Southeast University(English Edition)》 EI CAS 2005年第2期239-243,共5页
Some homological properties of R-modules were investigated by matrices over aring R. Given two cardinal numbers α, β and an α x β row-finite matrix A, it was proved thatExt_R^1(R^((α))/R^((β))A, M) = 0 if and on... Some homological properties of R-modules were investigated by matrices over aring R. Given two cardinal numbers α, β and an α x β row-finite matrix A, it was proved thatExt_R^1(R^((α))/R^((β))A, M) = 0 if and only if M_α/r_(M_α)(R^((β))A) ≈ Hom_R(R^((β))A,M) ifand only if r_(M_β)l_(R^((β)))(A) = AM_α. Thus, the notion of (m,n)-injectivity was extended.Moreover, ( α, β) -flatness was characterized via annihilators of matrices, factorizations ofhomomorphisms as well as homological groups so that (m, n)-flat modules, f-projective modules andn-projective modules were consolidated under the notion of (α, β)-flat modules. Furthermore, acharacterization of left R-ML modules and some equivalent conditions for R^((β)) to be left R-MLwere presented. Consequently, the notions of coherent rings, (m, n)-coherent rings and π-coherentrings were consolidated under that of (α, β)-coherent rings. 展开更多
关键词 β)-injective module β) -flat module R-ML module β)-coherent ring
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改进D-Linknet的眼底视网膜血管分割
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作者 徐武 沈智方 +2 位作者 范鑫豪 刘洋 徐天奇 《应用科技》 CAS 2024年第2期99-104,119,共7页
临床医生可通过观察眼底视网膜血管及其分支对人体是否患有疾病进行早期诊断,但由于视网膜中的血管错综复杂,模型在分割时会出现对微细血管分割精确度不足的问题。为此,提出一种结合残差模块Res2-net以及高效通道注意力机制(efficient c... 临床医生可通过观察眼底视网膜血管及其分支对人体是否患有疾病进行早期诊断,但由于视网膜中的血管错综复杂,模型在分割时会出现对微细血管分割精确度不足的问题。为此,提出一种结合残差模块Res2-net以及高效通道注意力机制(efficient channel attention,ECA)的D-Linknet模型。首先,利用Res2-net代替基础模型中的残差模块Res-net以提升每个网络层的感受野;其次,在Res2-net中添加一种结合压缩激励(squeeze and excitation,SE)和门通道(gated channel transformation,GCT)的注意力机制模块,改善处于复杂背景下的血管分割效果和效率;在网络的解码层加入ECA确保模型计算的性能,避免因降维导致的精度下降;最后,融合改进的模型输出图与掩膜图细化分割结果。在公开数据集DRIVE、STARE上进行分割实验,模型准确度(accuracy,AC)分别为97.11%、96.32%,灵敏度(sensitivity,SE)为84.55%、83.92%,曲线下方范围的面积(area under curve,AUC)为0.9873和0.9766,分割效果优于其他模型。实验证明了算法的可行性,为后续研究提供科学依据。 展开更多
关键词 图像分割 眼底视网膜血管 d-Linknet 残差模块 注意力机制 解码层 模型准确度 模型灵敏度
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西门子SIMADYND交-交变频主传动系统深度保养技术介绍
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作者 安宏亮 孔伟海 陈帅 《变频器世界》 2024年第7期112-115,共4页
变频器的维护与保养是确保其正常运行和延长使用寿命的重要环节。通过检查变频器的外部环境、电源及电气连接、散热器和风扇的清洁、绝缘性能的检查以及软件和固件的更新升级等,我们可以有效地管理和保养变频器,提高其可靠性和稳定性。
关键词 SIMAdYNd机箱 晶闸管 功率组件 脉冲测试
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Waveguide-integrated optical modulators with two-dimensional materials
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作者 Haitao Chen Hongyuan Cao +2 位作者 Zejie Yu Weike Zhao Daoxin Dai 《Journal of Semiconductors》 EI CAS CSCD 2023年第11期8-25,共18页
Waveguide-integrated optical modulators are indispensable for on-chip optical interconnects and optical computing.To cope with the ever-increasing amount of data being generated and consumed,ultrafast waveguide-integr... Waveguide-integrated optical modulators are indispensable for on-chip optical interconnects and optical computing.To cope with the ever-increasing amount of data being generated and consumed,ultrafast waveguide-integrated optical modulators with low energy consumption are highly demanded.In recent years,two-dimensional(2D)materials have attracted a lot of attention and have provided tremendous opportunities for the development of high-performance waveguide-integrated optical modulators because of their extraordinary optoelectronic properties and versatile compatibility.This paper reviews the state-of-the-art waveguide-integrated optical modulators with 2D materials,providing researchers with the developing trends in the field and allowing them to identify existing challenges and promising potential solutions.First,the concept and fundamental mechanisms of optical modulation with 2D materials are summarized.Second,a review of waveguide-integrated optical modulators employing electro-optic,all-optic,and thermo-optic effects is provided.Finally,the challenges and perspectives of waveguide-integrated modulators with 2D materials are discussed. 展开更多
关键词 optical modulation two-dimensional(2d)materials ON-CHIP WAVEGUIdE
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改进YOLOv7-tiny与D-S理论结合的实验室人员行为检测研究
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作者 杨永亮 曹敏 +4 位作者 徐凌桦 王霄 杨靖 王涛 冯平平 《现代电子技术》 北大核心 2024年第19期153-160,共8页
针对目前实验室场景缺少对人员行为检测的方法,且主流算法精度低、误检率高的问题,文中提出一种改进YOLOv7-tiny的人员行为检测算法,并通过多源信息融合,提高人员行为在实际实验室场景中的识别准确率。首先,在检测算法主干网络引入Ghost... 针对目前实验室场景缺少对人员行为检测的方法,且主流算法精度低、误检率高的问题,文中提出一种改进YOLOv7-tiny的人员行为检测算法,并通过多源信息融合,提高人员行为在实际实验室场景中的识别准确率。首先,在检测算法主干网络引入GhostNetV2轻量化网络,进一步降低模型计算量和复杂度;其次,在颈部网络嵌入改进后的CBAM_E注意力模块,加强目标重要特征的提取;再次,在预测端使用SIoU替换原有的损失函数,减少角度因素和边界框回归精度的影响。检测结果表明,相较于YOLOv7-tiny,文中算法精度提升10.08%,模型参数量和复杂度分别下降36.45%和46.76%。最后通过将检测数据与传感器采集数据运用D-S证据理论进行信息融合后发现,人员不规范行为检测的误检率得到有效降低。结果表明,该方法可实现对实验室人员不规范行为的有效检测。 展开更多
关键词 实验室场景 人员行为 YOLOv7-tiny 轻量化网络 注意力模块 损失函数 d-S证据理论 信息融合
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Expression analysis of the R2R3-MYB gene family in upland cotton and functional study of GhMYB3D5 in regulating Verticillium wilt resistance
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作者 Jie Liu Zhicheng Wang +15 位作者 Bin Chen Guoning Wang Huifeng Ke Jin Zhang Mengjia Jiao Yan Wang Meixia Xie Yanbin Li Dongmei Zhang Xingyi Wang Qishen Gu Zhengwen Sun Liqiang Wu Xingfen Wang Zhiying Ma Yan Zhang 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第10期3294-3310,共17页
Improving plant resistance to Verticillium wilt(VW),which causes massive losses in Gossypium hirsutum,is a global challenge.Crop plants need to efficiently allocate their limited energy resources to maintain a balance... Improving plant resistance to Verticillium wilt(VW),which causes massive losses in Gossypium hirsutum,is a global challenge.Crop plants need to efficiently allocate their limited energy resources to maintain a balance between growth and defense.However,few transcriptional regulators specifically respond to Verticillium dahliae and the underlying mechanism has not been identified in cotton.In this study,we found that the that expression of most R2R3-MYB members in cotton is significantly changed by V.dahliae infection relative to the other MYB types.One novel R2R3-MYB transcription factor(TF)that specifically responds to V.dahliae,GhMYB3D5,was identified.GhMYB3D5 was not expressed in 15 cotton tissues under normal conditions,but it was dramatically induced by V.dahliae stress.We functionally characterized its positive role and underlying mechanism in VW resistance.Upon V.dahliae infection,the up-regulated GhMYB3D5 bound to the GhADH1 promoter and activated GhADH1expression.In addition,GhMYB3D5 physically interacted with GhADH1 and further enhanced the transcriptional activation of GhADH1.Consequently,the transcriptional regulatory module GhMYB3D5-GhADH1 then promoted lignin accumulation by improving the transcriptional levels of genes related to lignin biosynthesis(GhPAL,GhC4H,Gh4CL,and GhPOD/GhLAC)in cotton,thereby enhancing cotton VW resistance.Our results demonstrated that the GhMYB3D5 promotes defense-induced lignin accumulation,which can be regarded as an effective way to orchestrate plant immunity and growth. 展开更多
关键词 COTTON Verticillium wilt resistance GhMYB3d5 GhAdH1 transcriptional regulatory module
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基于Production Module 3D数控铣削仿真技术在钛合金主吊挂加工中的应用 被引量:2
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作者 吴东华 邓志刚 +2 位作者 张德纯 赵万岳 丁代华 《机械工程师》 2021年第11期149-152,155,共5页
在钛合金主吊挂支架的铣削过程中,采用Production Module 3D软件对数控程序、材料、刀具及工件的综合分析,得到了在整个数控程序下的温度峰值、进给力、切削力及材料去除率等数据。然后采用完善数控程序中的吃刀量、切削速度及进给量来... 在钛合金主吊挂支架的铣削过程中,采用Production Module 3D软件对数控程序、材料、刀具及工件的综合分析,得到了在整个数控程序下的温度峰值、进给力、切削力及材料去除率等数据。然后采用完善数控程序中的吃刀量、切削速度及进给量来使加工过程中温度、切削力等符合要求,使负载平衡,降低振动。最终刀具的使用寿命提高20%,加工周期降低22%。 展开更多
关键词 钛合金 铣削 Production module 3d
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基于跨模态特征融合的RGB-D显著性目标检测
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作者 李可新 何丽 +1 位作者 刘哲凝 钟润豪 《国外电子测量技术》 2024年第6期59-67,共9页
RGB-D显著性目标检测因其有效性和易于捕捉深度线索而受到越来越多的关注。现有的工作通常侧重于通过各种融合策略学习共享表示,少有方法明确考虑如何维持RGB和深度的模态特征。提出了一种跨模态特征融合网络,该网络维持RGB-D显著目标... RGB-D显著性目标检测因其有效性和易于捕捉深度线索而受到越来越多的关注。现有的工作通常侧重于通过各种融合策略学习共享表示,少有方法明确考虑如何维持RGB和深度的模态特征。提出了一种跨模态特征融合网络,该网络维持RGB-D显著目标检测的RGB和深度的模态,通过探索共享信息以及RGB和深度模态的特性来提高显著检测性能。具体来说,采用RGB模态、深度模态网络和一个共享学习网络来生成RGB和深度模态显著性预测图以及共享显著性预测图。提出了一种跨模态特征融合模块,用于融合共享学习网络中的跨模态特征,然后将这些特征传播到下一层以整合跨层次信息。此外,提出了一种多模态特征聚合模块,将每个单独解码器的模态特定特征整合到共享解码器中,这可以提供丰富的互补多模态信息来提高显著性检测性能。最后,使用跳转连接来组合编码器和解码器层之间的分层特征。通过在4个基准数据集上与7种先进方法进行的实验表明,方法优于其他最先进的方法。 展开更多
关键词 RGB-d显著性目标检测 跨模态融合网络 跨模态特征融合 多模态聚合
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Dye-sensitized solar cell module realized photovoltaic and photothermal highly efficient conversion via three-dimensional printing technology
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作者 黄启章 朱艳青 +3 位作者 史继富 王雷雷 钟柳文 徐刚 《Chinese Physics B》 SCIE EI CAS CSCD 2017年第3期575-581,共7页
Three-dimensional (3D) printing technology is employed to improve the photovoltaic and photothermal conversion efficiency of dye-sensitized solar cell (DSC) module. The 3D-printed concentrator is optically designe... Three-dimensional (3D) printing technology is employed to improve the photovoltaic and photothermal conversion efficiency of dye-sensitized solar cell (DSC) module. The 3D-printed concentrator is optically designed and improves the photovoltaic efficiency of the DSC module from 5.48% to 7.03%. Additionally, with the 3D-printed microfluidic device serving as water cooling, the temperature of the DSC can be effectively controlled, which is beneficial for keeping a high photovoltaic conversion efficiency for DSC module. Moreover, the 3D-printed microfluidic device can realize photothermal conversion with an instantaneous photothermal efficiency of 42.1%. The integrated device realizes a total photovoltaic and photothermal conversion efficiency of 49% at the optimal working condition. 展开更多
关键词 3d printing dye-sensitized solar cell module CONCENTRATOR microfluidic
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Penrose Transform on <i>D</i>-Modules, Moduli Spaces and Field Theory
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作者 Francisco Bulnes 《Advances in Pure Mathematics》 2012年第6期379-390,共12页
We consider a generalization of the Radon-Schmid transform on coherent D-modules of sheaves of holomorphic complex bundles inside a moduli space, with the purpose of establishing the equivalences among geometric objec... We consider a generalization of the Radon-Schmid transform on coherent D-modules of sheaves of holomorphic complex bundles inside a moduli space, with the purpose of establishing the equivalences among geometric objects (vector bundles) and algebraic objects as they are the coherent D-modules, these last with the goal of obtaining conformal classes of connections of the holomorphic complex bundles. The class of these equivalences conforms a moduli space on coherent sheaves that define solutions in field theory. Also by this way, and using one generalization of the Penrose transform in the context of coherent D-modules we find conformal classes of the space-time that include the heterotic strings and branes geometry. 展开更多
关键词 Penrose Transform Coherent d-moduleS derived SHEAF modulI Space Conformal Classes Heterotic Strings
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Penrose Transform on Induced <i>D<sub>G/H</sub></i>-Modules and Their Moduli Stacks in the Field Theory
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作者 Francisco Bulnes 《Advances in Pure Mathematics》 2013年第2期246-253,共8页
We consider generalizations of the Radon-Schmid transform on coherent DG/H-Modules, with the intention of obtaining the equivalence between geometric objects (vector bundles) and algebraic objects (D-Modules) characte... We consider generalizations of the Radon-Schmid transform on coherent DG/H-Modules, with the intention of obtaining the equivalence between geometric objects (vector bundles) and algebraic objects (D-Modules) characterizing conformal classes in the space-time that determine a space moduli [1] on coherent sheaves for the securing solutions in field theory [2]. In a major context, elements of derived categories like D-branes and heterotic strings are considered, and using the geometric Langlands program, a moduli space is obtained of equivalence between certain geometrical pictures (non-conformal world sheets [3]) and physical stacks (derived sheaves), that establishes equivalence between certain theories of super symmetries of field of a Penrose transform that generalizes the implications given by the Langlands program. With it we obtain extensions of a cohomology of integrals for a major class of field equations to corresponding Hecke category. 展开更多
关键词 Penrose Transform Coherent G-Quasi-Equivariant d-moduleS HECKE SHEAF modulI STACKS modulI Spaces
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The hypothalamic-spinal dopaminergic system:a target for pain modulation 被引量:10
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作者 Michelino Puopolo 《Neural Regeneration Research》 SCIE CAS CSCD 2019年第6期925-930,共6页
Nociceptive signals conveyed to the dorsal horn of the spinal cord by primary nociceptors are subject to extensive modulation by local neurons and by supraspinal descending pathways to the spinal cord before being rel... Nociceptive signals conveyed to the dorsal horn of the spinal cord by primary nociceptors are subject to extensive modulation by local neurons and by supraspinal descending pathways to the spinal cord before being relayed to higher brain centers. Descending modulatory pathways to the spinal cord comprise,among others, noradrenergic, serotonergic, γ-aminobutyric acid(GABA)ergic, and dopaminergic fibers.The contributions of noradrenaline, serotonin, and GABA to pain modulation have been extensively investigated. In contrast, the contributions of dopamine to pain modulation remain poorly understood.The focus of this review is to summarize the current knowledge of the contributions of dopamine to pain modulation. Hypothalamic A11 dopaminergic neurons project to all levels of the spinal cord and provide the main source of spinal dopamine. Dopamine receptors are expressed in primary nociceptors as well as in spinal neurons located in different laminae in the dorsal horn of the spinal cord, suggesting that dopamine can modulate pain signals by acting at both presynaptic and postsynaptic targets. Here, I will review the literature on the effects of dopamine and dopamine receptor agonists/antagonists on the excitability of primary nociceptors, the effects of dopamine on the synaptic transmission between primary nociceptors and dorsal horn neurons, and the effects of dopamine on pain in rodents. Published data support both anti-nociceptive effects of dopamine mediated by D2-like receptors and pro-nociceptive effects mediated by D1-like receptors. 展开更多
关键词 A11 nucleus dESCENdING modulation dopamine dORSAL horn dORSAL root GANGLIA d2 RECEPTORS d1 RECEPTORS NOCICEPTORS pain SPINAL cord
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Modulation of the thermal transport of micro-structured materials from 3D printing 被引量:5
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作者 Qiangsheng Sun Zhixiang Xue +5 位作者 Yang Chen Ruding Xia Jianmei Wang Shen Xu Jun Zhang Yanan Yue 《International Journal of Extreme Manufacturing》 SCIE EI 2022年第1期22-33,共12页
It is desirable to fabricate materials with adjustable physical properties that can be used in different industrial applications.Since the property of a material is highly dependent on its inner structure,the understa... It is desirable to fabricate materials with adjustable physical properties that can be used in different industrial applications.Since the property of a material is highly dependent on its inner structure,the understanding of structure–property correlation is critical to the design of engineering materials.3D printing appears as a mature method to effectively produce micro-structured materials.In this work,we created different stainless-steel microstructures by adjusting the speed of 3D printing and studied the relationship between thermal property and printing speed.Our microstructure study demonstrates that highly porous structures appear at higher speeds,and there is a nearly linear relationship between porosity and printing speed.The thermal conductivity of samples fabricated by different printing speeds is characterized.Then,the correlation between porosity,thermal conductivity,and scanning speed is established.Based on this correlation,the thermal conductivity of a sample can be predicted from its printing speed.We fabricated a new sample at a different speed,and the thermal conductivity measurement agrees well with the value predicted from the correlation.To explore thermal transport physics,the effects of pore structure and temperature on the thermal performance of the printed block are also studied.Our work demonstrates that the combination of the 3D printing technique and the printing speed control can regulate the thermophysical properties of materials. 展开更多
关键词 modulATION thermal property MICROSTRUCTURE 3d printing SPEEd
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基于CPLD控制模块的智能机器人控制系统研究 被引量:4
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作者 李贺 朱珍元 陈任 《计算机测量与控制》 2023年第2期147-153,共7页
为提高物流周转智能机器人的环境感知能力和避障能力,降低智能机器人运行中碰撞障碍物的概率,设计了一种基于CPLD控制模块的物流周转智能机器人控制系统;以CPLD控制器为核心,调整A/D模拟采集接口模块信号的连接形式,并设置与PWM寄存器... 为提高物流周转智能机器人的环境感知能力和避障能力,降低智能机器人运行中碰撞障碍物的概率,设计了一种基于CPLD控制模块的物流周转智能机器人控制系统;以CPLD控制器为核心,调整A/D模拟采集接口模块信号的连接形式,并设置与PWM寄存器相关的连接参数;给出了主机智能程序的决策流程,并适时调整PWM寄存器的整流参数,提升控制指令执行向量的匹配精度,以实现对智能机器人运动轨迹的精确控制;与传统机器人控制系统相比,基于CPLD控制模块的智能机器人能够更准确地感知外界环境的变化,精确规避障碍物。 展开更多
关键词 CPLd控制模块 智能机器人 A/d模拟 PWM寄存器 避障敏感度
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The Realization of Mass Customization Using Modularization Method
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作者 SU Ju-ning 1, YANG Shui-li 1, DONG Peng-fei 2 (1. School of Business Administration, Xi’an University of Technology, Xi’an 710048, China 2. Jinduicheng Molybdenum Mining Corporation, Huaxian 714102, China) 《厦门大学学报(自然科学版)》 CAS CSCD 北大核心 2002年第S1期244-,共1页
In the view of the comparison of Mass Customization ( MC) with Mass Production and Customization Production, the objectives of MC are analyzed. It is pointed out that the core objectives of MC are to realize in dividu... In the view of the comparison of Mass Customization ( MC) with Mass Production and Customization Production, the objectives of MC are analyzed. It is pointed out that the core objectives of MC are to realize in dividuation customization, low cost, quick response to market demands. The modul arization theory is simply introduced. Based on the characteristics of modular ization, the mechanism of realizing MC with modularization is analyzed. The in dividuation customization can be realized with the different combinations of mod ules. The low cost can be realized with the scale economy and the category econo my of modules. The quick response can be realized with standard modules and its interfaces. So, the modularization is a kind of effective method in realizing MC . The modularization for MC is a systems engineering. With product modularized, production organization and management and manufacturing equipment will be chang ed. In addition, the paper also proposes a Mass Customization production model w hich is based on modularization. This Mass Customization production model is con sisted of modularization of product design, specialization of manufacturing, Vir tual Enterprises based on modularizing enterprises, and modularizing manufacturi ng equipment. The module design for MC, modularizing enterprises, and reconfigur able automation manufacturing equipment are discussed, and it is pointed out tha t they are the important supports for MC. 展开更多
关键词 Mass Customization (MC) modulARIZATION module d esign modularizing enterprise reconfigurable automation manufacturing equipmen t
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Modulation Effects of the 3D Strain Microenvironment on Characteristics of Mesenchymal Stem Cell-Derived Exosomes
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作者 Yufei Ma Wenting Yu Feng Xu 《医用生物力学》 EI CAS CSCD 北大核心 2019年第A01期128-129,共2页
It is necessary to investigate the characteristics of Mesenchymal stem cells(MSCs)derived exosomes,and especially their application in tissue regeneration.Previous studies have shown that inflammatory stimulation enha... It is necessary to investigate the characteristics of Mesenchymal stem cells(MSCs)derived exosomes,and especially their application in tissue regeneration.Previous studies have shown that inflammatory stimulation enhanced the secretion of MSC-derived exosomes with stronger anti-inflammatory protein,cytokine profiles,and functional RNA via altering COX2/PGE2 pathway.Recently,accumulating evidence has also revealed that biophysical cues(especially biomechanical cues)in cell microenvironment have significant effects not only on cells but also on their exosomes.It has been reported that applying bi-axial strain to MSCs induces formation of a stiffer cytoskeleton through mTORC2 signaling,which biases against adipogenic differentiation and toward osteoblastogenesis.At the same time,For example,dimensionality,composition and stiffness of the extracellular matrix(ECM)has been proved to affect the size and composition of exosomes secreted by cancer cells.However,the effects of biomechanical cues in the three-dimensional(3D)microenvironment on stem cell-derived exosomes remains to be unveiled.Therefore,it is important to understand the roles of 3D cell mechanical microenvironment in regulating the characteristics of stem cell-derived exosomes and develop more efficient approaches to enhance their functions.This study aimed to explore the changes in characteristics of exosomes secreted by MSCs in periodontium in response to the matrix strain in 3D.Periodontal ligament stem cells(PDLSCs)were cultured in a 3D strain microenvironment engineered with microscale magnetically stretched collagen hydrogels.The morphology,particle distribution,marker protein expression of PDLSC-derived exosomes were analyzed.Then the pro-osteogenic property of exosomes was evaluated by assessing cell viability,proliferation,migration and osteogenic differentiation of target cells,for instance human bone marrow mesenchymal stem cells(hBMSCs).Detailed characterizations revealed that PDLSC-derived exosomes in the 3D strain mi-croenvironment were with similar morphology,particle distribution and surface markers.Notably,Exosomes secreted by PDLSCs in strain microenvironment were more endocytosed by hBMSCs and were more potent in improving proliferation and migration of hBMSCs,comparing with PDLSCs in non-strain environment.Alizarin red staining and molecular biology experiments confirmed that treatment of exosomes secreted by PDLSCs under mechanical stimulation led to a significant increase in osteogenic differentiation of hBMSCs in vitro.Meanwhile,in vivo study also indicated that PDLSC-derived exosomes obtained from the 3D strain microenvironment could obviously promote new bone formation.Our findings revealed that mechanical cues profoundly affected the characteristics of PDLSC-derived exosomes,especially for their bio-activity,providing a foundation for using the 3D mechanical microenvironment to enhance the osteo-inductive functions of stem cell-derived exosomes in cell-free therapy for bone regeneration. 展开更多
关键词 modulation Effects the 3d STRAIN MICROENVIRONMENT CHARACTERISTICS Mesenchymal Stem Cell-derived EXOSOMES
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A simple 2D modulation code in single-reader two-track reading BPMR systems
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作者 Wiparat Busyatras Chanon Warisarn +1 位作者 Santi Koonkarnkhai Piya Kovintavewat 《Digital Communications and Networks》 SCIE CSCD 2021年第1期100-106,共7页
A reduction in the track width of magnetic recording systems results in a welcome increase in Areal Density(AD),but can severely deteriorate system performance in the unfortunate appearance of extreme Inter-Track Inte... A reduction in the track width of magnetic recording systems results in a welcome increase in Areal Density(AD),but can severely deteriorate system performance in the unfortunate appearance of extreme Inter-Track Interference(ITI).The effect of severe ITI may be mitigated by using coding schemes.In this paper,therefore,we present a rate-5/62-Dimensional(2D)modulation code based on a proposed Single-Reader/Two-track Reading(SRTR)technique to cope with this serious problem in staggered Bit-Pattemed Magnetic Recording(BPMR)systems.We then evaluate the Bit-Error Rate(BER)performance of the proposed system in the presence of media noises,e.g.,position and size fluctuations.Our simulation results indicate that,at the same User Density(UD),the proposed system performs better than an uncoded system by about 1.0 dB at the BER of 105 and is also superior to the conventional recording system. 展开更多
关键词 Bit-pattemed media recording 2d interference 2d modulation code Single-reader/two-track reading
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Pulse modulated microwave and infrared thermography for superficial hyperthermia
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作者 马国军 江国泰 陈志宏 《Journal of Central South University》 SCIE EI CAS 2012年第7期1927-1931,共5页
A 3D temperature field distribution of biological tissue for superficial hyperthermia using a pulse modulated microwave (PMMW) was presented. A 3D sliced homogeneous phantom was radiated by the PMMW and an infrared ... A 3D temperature field distribution of biological tissue for superficial hyperthermia using a pulse modulated microwave (PMMW) was presented. A 3D sliced homogeneous phantom was radiated by the PMMW and an infrared thermal imager was applied to image temperature distribution throughout the phantom. The period of the PMMW is 3 s and the output power is 35 W. The temperature rises by at least 3 ℃ in the phantom when the duty cycle varies from 1/3, 1/2, 2/3 to 1 (denoted by scenarios 1-4). Both the accumulative temperature-volume histogram and the relative depth-area ratio histogram show that the maximum temperature rise (MTR) is 6.6 and 8 ℃ in scenarios 2 and 3, and they are superior to scenarios 1 and 4. Furthermore, the PMMW can control temperature field distribution of biological tissue. It provides both preliminary basis for thermal volume control and new technology for temperature control and monitor in superficial hyperthermia. 展开更多
关键词 3d temperature field distribution pulse modulated microwave (PMMW) infrared thermography superficialhyperthermia
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Electronic structure modulation with ultrafine Fe_(3)O_(4) nanoparticles on 2D Ni-based metal-organic framework layers for enhanced oxygen evolution reaction
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作者 Wei Huang Chao Peng +7 位作者 Jing Tang Fangyuan Diao Murat Nulati Yesibolati Hongyu Sun Christian Engelbrekt Jingdong Zhang Xinxin Xiao Kristian S.Mølhave 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2022年第2期78-88,共11页
Two-dimensional(2D)metal organic frameworks(MOFs)are emerging as low-cost oxygen evolution reaction(OER)electrocatalysts,however,suffering aggregation and poor operation stability.Herein,ultrafine Fe_(3)O_(4) nanopart... Two-dimensional(2D)metal organic frameworks(MOFs)are emerging as low-cost oxygen evolution reaction(OER)electrocatalysts,however,suffering aggregation and poor operation stability.Herein,ultrafine Fe_(3)O_(4) nanoparticles(diameter:6±2 nm)are homogeneously immobilized on 2D Ni based MOFs(Ni-BDC,thickness:5±1 nm)to improve the OER stability.Electronic structure modulation for enhanced catalytic activity is studied via adjusting the amount of Fe_(3)O_(4) nanoparticles on Ni-BDC.The optimal Fe_(3)O_(4)/Ni-BDC achieves the best OER performance with an overpotential of 295 mV at 10 mA cm^(-2),a Tafel slope of 47.8 mV dec^(-1) and a considerable catalytic durability of more than 40 h(less than 5 h for Ni-BDC alone).DFT calculations confirm that the active sites for Fe_(3)O_(4)/Ni-BDC are mainly contributed by Fe species with a higher oxidation state,and the potential-determining step(PDS)is the formation of the adsorbed O*species,which are facilitated in the composite. 展开更多
关键词 Fe_(3)O_(4)nanoparticles 2d Ni-BdC Aggregation Electronic structure modulation Oxygen evolution reaction
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