Tight sandstone reservoir sensitivity and damage mechanism analysis: A case study from Ordos Basin, China and implications for reservoir damage prevention

Analysis of reservoir sensitivity to velocity,water,salt,acid,alkali and stress is critical for reservoir protection.To study the tight sandstone reservoir sensitivity at different formation depths(effective stress)and formation water conditions(pH,salinity,and fluid velocity),a series of dynamic core flow tests under different pH,salinity,acid,and effective stress conditions were performed on samples from tight sandstone reservoirs of the Upper Triassic Yanchang 8(T_(3)y^(8))Member and conventional reservoirs of the Middle-Lower Jurassic Yan'an 9(J_(1-2)y^(9))Member in the Ordos Basin.The results indicate that,compared with the conventional reservoirs,the tight sandstone reservoirs are more sensitive to velocity and stress,less sensitive to water,alkali and salinity,and respond better to acid fracturing.In addition,the critical conditions(salinity,velocity,pH,and stress)for pumping drilling,completion,and fracturing fluids into tight sandstone reservoirs were investigated.A combination of scanning electron microscopy coupled with energy-dispersive spectrometry(SEM-EDS),cathodoluminescence(CL),casting thin section(CTS)and nuclear magnetic resonance(NMR)images,high-pressure mercury injection capillary pressure(MICP)measurements as well as X-ray fluorescence spectral(XRF)analyses were employed to analyze the damage mechanisms of the conventional reservoirs(J_(1-2)y^(9))and tight sandstone reservoirs(T_(3)y^(8))caused by fluid invasion.The results suggest that reservoir sensitivity is primarily conditioned by the composition of detrital components and interstitial fillings,petrophysical properties,pore-throat structure,and diagenetic facies.All these factors control the sensitivity types and extent of the reser-voirs.Our results indicate that the poorer the reservoir physical properties,the stronger the reservoir heterogeneity and sensitivity,implying that tight sandstone reservoirs are more susceptible to changes in fluids than conventional reservoirs.This study offers insights into the reservoir damage types and helps to improve the design and implementation of protection measures for tight sandstone reservoir exploration.

Green Tea Chemical May Prevent Brain Damage

绿茶对人体健康是否有利。这个问题似乎一直没有一个科学的论证。本文是一个先例。据最新一期美国《全国科学院学报》报道,美国老兵事务医疗中心的科学家发现。绿茶中含有的化学物质可以预防在中风和其他脑组织受伤后发生的脑损或脑死亡。在中风和其他脑部损伤时,脑细胞会因过度活跃而引发自身死亡,这主要是由于人体内脱氧核糖核酸修复系统(即PARP/PARG系统)过度活跃所造成的,我们可以通过阻止这些系统过度活跃而拯救濒临死亡的脑细胞。科学家测试了从绿茶中提取的两种化学物质对受伤脑细胞的影响,结 果发现,这些化学物质对阻止脑部细胞过度活跃有很好的功效。

Preventive effect of Fangshuan capsule on PCI-induced myocardial damage and vascular endothelial injury in patients with unstable angina pectoris

Objective To observe the prevention of Fangshuan Capsule(FC)on percutaneous coronary intervention(PCI)induced myocardial damage and vascular endothelial injury in patients with unstable angina pectoris(UAP).Methods Totally 100 UAP patients undergoing PCI were assigned to the control group and the

DETACHED EDDY SIMULATION OF HYDRAULIC CHARACTERISTICS ALONG THE SIDE-WALL AFTER A NEW ARRANGEMENT-SCHEME OF THE SUDDEN LATERAL ENLARGEMENT AND THE VERTICAL DROP

In order to study the cavitation damage in a side-wall when a sudden lateral enlargement and a vertical drop are imposed at the radial gate, a new arrangement-scheme is proposed, where the sudden lateral enlargement and the vertical drop can be imposed at the outlet of the gate chamber. The hydraulic characteristics along the side-wall are simulated by the detached eddy simulation and the Volume Of Fluid （VOF） method. The numerical results agree well with those of experiment. The experimental and numerical results show that the flow condition is smooth with only a weak water-wing appearing behind the lateral cavity, and the length of the lateral cavity becomes longer and is mainly affected by the size of the lateral enlargement and the zone of negative pressure after the water impacts the side-wall would disappear. The hydraulic characteristics of the new arrangement-scheme are beneficial to the prevention of the cavitation damage in the side-wall and the Detached Eddy Simulation （DES） with the VOF method can well predict the hydraulic characteristics after the new arrangement-scheme of the sudden lateral enlargement and the vertical drop.

Neuroprotective Effects of Electroacupuncture Preventive Treatment in Senescence-Accelerated Mouse Prone 8 Mice

Objective： To investigate the preventive treatment effects of electroacupuncture（EA） on cognitive changes and brain damage in senescence-accelerated mouse prone 8（SAMP8） mice. Methods： The 5-month-old male SAMP8 and age-matched homologous normal aging mice（SAMR1） were adopted in this study. EA stimulation at Baihui（GV 20） and Yintang（EX-HN 3） was performed every other day for 12 weeks, 4 weeks as a course. Morris water maze test and Nissl-stained with cresyl violet were used for cognitive impairments evaluation and brain morphometric analysis. Amyloid-β（Aβ） expression in hippocampus and parietal cortex was detected by immunohistochemistry, and apoptosis was observed by TUNEL staining. Results： After 3 courses of EA preventive treatment, the escape latencies of 8-month-old SAMP8 mice in EA group were significantly shortened than those of un-pretreated SAMP8 mice. Compared with SAMR1 mice, extensive neuronal changes were visualized in the CA1 area of hippocampus in SAMP8 mice, while these pathological changes and attenuate cell loss in hippocampal CA1 area of SAMP8 mice markedly reduced after EA preventive treatment. Furthermore, Aβ expression in hippocampus and parietal cortex of SAMP8 mice decreased significantly after EA treatment, and neuronal apoptosis decreased as well. Conclusion： EA preventive treatment at GV 20 and EX-HN 3 might improve cognitive deficits and neuropathological changes in SAMP8 mice, which might be, at least in part, due to the effects of reducing brain neuronal damage, decreasing neuronal apoptosis and inhibiting Aβ-containing aggregates.