Bayesian and Non-Bayesian Analysis for the Sine Generalized Linear Exponential Model under Progressively Censored Data

This article introduces a novel variant of the generalized linear exponential(GLE)distribution,known as the sine generalized linear exponential(SGLE)distribution.The SGLE distribution utilizes the sine transformation to enhance its capabilities.The updated distribution is very adaptable and may be efficiently used in the modeling of survival data and dependability issues.The suggested model incorporates a hazard rate function(HRF)that may display a rising,J-shaped,or bathtub form,depending on its unique characteristics.This model includes many well-known lifespan distributions as separate sub-models.The suggested model is accompanied with a range of statistical features.The model parameters are examined using the techniques of maximum likelihood and Bayesian estimation using progressively censored data.In order to evaluate the effectiveness of these techniques,we provide a set of simulated data for testing purposes.The relevance of the newly presented model is shown via two real-world dataset applications,highlighting its superiority over other respected similar models.

Using Extreme Value Theory Approaches to Estimate High Quantiles for Stroke Data

This paper aims to explore the application of Extreme Value Theory (EVT) in estimating the conditional extreme quantile for time-to-event outcomes by examining the functional relationship between ambulatory blood pressure trajectories and clinical outcomes in stroke patients. The study utilizes EVT to analyze the functional connection between ambulatory blood pressure trajectories and clinical outcomes in a sample of 297 stroke patients. The 24-hour ambulatory blood pressure measurement curves for every 15 minutes are considered, acknowledging a censored rate of 40%. The findings reveal that the sample mean excess function exhibits a positive gradient above a specific threshold, confirming the heavy-tailed distribution of data in stroke patients with a positive extreme value index. Consequently, the estimated conditional extreme quantile indicates that stroke patients with higher blood pressure measurements face an elevated risk of recurrent stroke occurrence at an early stage. This research contributes to the understanding of the relationship between ambulatory blood pressure and recurrent stroke, providing valuable insights for clinical considerations and potential interventions in stroke management.

A class of estimators of the mean survival time from interval censored data with application to linear regression

A class of estimators of the mean survival time with interval censored data are studied by unbiased transformation method. The estimators are constructed based on the observations to ensure unbiasedness in the sense that the estimators in a certain class have the same expectation as the mean survival time. The estimators have good properties such as strong consistency （with the rate of O（n^-1/1 （log log n）^1/2）） and asymptotic normality. The application to linear regression is considered and the simulation reports are given.

EMPIRICAL LIKELIHOOD-BASED INFERENCE IN LINEAR MODELS WITH INTERVAL CENSORED DATA

An empirical likelihood approach to estimate the coefficients in linear model with interval censored responses is developed in this paper. By constructing unbiased transformation of interval censored data,an empirical log-likelihood function with asymptotic X^2 is derived. The confidence regions for the coefficients are constructed. Some simulation results indicate that the method performs better than the normal approximation method in term of coverage accuracies.

KERNEL ESTIMATION OF HIGHER DERIVATIVES OF DENSITY AND HAZARD RATE FUNCTION FOR TRUNCATED AND CENSORED DEPENDENT DATA

Based on left truncated and right censored dependent data, the estimators of higher derivatives of density function and hazard rate function are given by kernel smoothing method. When observed data exhibit α-mixing dependence, local properties including strong consistency and law of iterated logarithm are presented. Moreover, when the mode estimator is defined as the random variable that maximizes the kernel density estimator, the asymptotic normality of the mode estimator is established.

ESTIMATORS AND SOME BEHAVIORS FORA PARTIALLY LINEAR MODEL WITH CENSORED DATA

This paper considers the local linear regression estimators for partially linear model with censored data. Which have some nice large-sample behaviors and are easy to implement. By many simulation runs, the author also found that the estimators show remarkable in the small sample case yet.

ESTIMATION FOR THE AYMPTOTIC VARIANCE OF PARAMETRIC ESTIMATES IN PARTIAL LINEAR MODEL WITH CENSORED DATA

Consider tile partial linear model Y=Xβ+ g(T) + e. Wilers Y is at risk of being censored from the right, g is an unknown smoothing function on [0,1], β is a 1-dimensional parameter to be estimated and e is an unobserved error. In Ref[1,2], it wes proved that the estimator for the asymptotic variance of βn(βn) is consistent. In this paper, we establish the limit distribution and the law of the iterated logarithm for,En, and obtain the convergest rates for En and the strong uniform convergent rates for gn(gn).

Bayesian Study Using MCMC of Three-Parameter Frechet Distribution Based on Type-I Censored Data

Type-I censoring mechanism arises when the number of units experiencing the event is random but the total duration of the study is fixed. There are a number of mathematical approaches developed to handle this type of data. The purpose of the research was to estimate the three parameters of the Frechet distribution via the frequentist Maximum Likelihood and the Bayesian Estimators. In this paper, the maximum likelihood method (MLE) is not available of the three parameters in the closed forms;therefore, it was solved by the numerical methods. Similarly, the Bayesian estimators are implemented using Jeffreys and gamma priors with two loss functions, which are: squared error loss function and Linear Exponential Loss Function (LINEX). The parameters of the Frechet distribution via Bayesian cannot be obtained analytically and therefore Markov Chain Monte Carlo is used, where the full conditional distribution for the three parameters is obtained via Metropolis-Hastings algorithm. Comparisons of the estimators are obtained using Mean Square Errors (MSE) to determine the best estimator of the three parameters of the Frechet distribution. The results show that the Bayesian estimation under Linear Exponential Loss Function based on Type-I censored data is a better estimator for all the parameter estimates when the value of the loss parameter is positive.

Inference and optimal design on step-stress partially accelerated life test for hybrid system with masked data

Under Type-Ⅱ progressively hybrid censoring, this paper discusses statistical inference and optimal design on stepstress partially accelerated life test for hybrid system in presence of masked data. It is assumed that the lifetime of the component in hybrid systems follows independent and identical modified Weibull distributions. The maximum likelihood estimations(MLEs)of the unknown parameters, acceleration factor and reliability indexes are derived by using the Newton-Raphson algorithm. The asymptotic variance-covariance matrix and the approximate confidence intervals are obtained based on normal approximation to the asymptotic distribution of MLEs of model parameters. Moreover,two bootstrap confidence intervals are constructed by using the parametric bootstrap method. The optimal time of changing stress levels is determined under D-optimality and A-optimality criteria.Finally, the Monte Carlo simulation study is carried out to illustrate the proposed procedures.

STRONG REPRESENTATIONS OF THE SURVIVAL FUNCTION ESTIMATOR ON INCREASING SETS FOR TRUNCATED AND CENSORED DATA

In this paper, based on random left truncated and right censored data, the authors derive strong representations of the cumulative hazard function estimator and the product-limit estimator of the survival function. which are valid up to a given order statistic of the observations. A precise bound for the errors is obtained which only depends on the index of the last order statistic to be included.

A KERNEL ESTIMATOR OF A DENSITY FUNCTION IN MULTIVARIATE CASE FROM RANDOMLY CENSORED DATA

A kernel density estimator is proposed when tile data are subject to censorship in multivariate case. The asymptotic normality, strong convergence and asymptotic optimal bandwidth which minimize the mean square error of the estimator are studied.

Functional Kernel Estimation of the Conditional Extreme Quantile under Random Right Censoring

The study of estimation of conditional extreme quantile in incomplete data frameworks is of growing interest. Specially, the estimation of the extreme value index in a censorship framework has been the purpose of many investigations when finite dimension covariate information has been considered. In this paper, the estimation of the conditional extreme quantile of a heavy-tailed distribution is discussed when some functional random covariate (i.e. valued in some infinite-dimensional space) information is available and the scalar response variable is right-censored. A Weissman-type estimator of conditional extreme quantiles is proposed and its asymptotic normality is established under mild assumptions. A simulation study is conducted to assess the finite-sample behavior of the proposed estimator and a comparison with two simple estimations strategies is provided.

Life Distribution Transformation Model of Planetary Gear System

Planetary gear systems have been widely used in transportation, construction, metallurgy, petroleum, aviation and other industrial fields. Under the same condition of power transmission, they have a more compact structure than ordinary gear train. However, some critical parts, such as sun gear, planet gear and ring gear often suffer from fatigue and wear under the conditions of high speed and heavy load. For reliability research, in order to predict the fatigue probability life of planetary gear system, detailed kinematic and mechanical analysis for a planetary gear system is firstly completed. Meanwhile, a gear bending fatigue test is carried out at a stress level to obtain the strength information of specific gears. Then, a life distribution transformation model is established according to the order statistics theory. Transformation process is that, the life distribution of test gear is transformed to that of single tooth, and then the life distribution of single tooth can be effectively transformed to that of the planetary gear system. In addition, the effectiveness of the transformation model is finally verified by a processing method with random censoring data.

Nonparametric Estimation of Interval-censored Failure Time Data in the Presence of Informative Censoring

Nonparametric estimation of a survival function is one of the most commonly asked questions in the analysis of failure time data and for this, a number of procedures have been developed under various types of censoring structures （Kalbfleisch and Prentice, 2002）. In particular, several algorithms are available for interval-censored failure time data with independent censoring mechanism （Sun, 2006; Turnbull, 1976）. In this paper, we consider the interval-censored data where the censoring mechanism may be related to the failure time of interest, for which there does not seem to exist a nonparametric estimation procedure. It is well-known that with informative censoring, the estimation is possible only under some assumptions. To attack the problem, we take a copula model approach to model the relationship between the failure time of interest and censoring variables and present a simple nonparametric estimation procedure. The method allows one to conduct a sensitivity analysis among others.

k-NN METHOD IN PARTIAL LINEAR MODEL UNDER RANDOM CENSORSHIP

Consider the regression model Y=Xβ+ g(T) + e. Here g is an unknown smoothing function on [0, 1], β is a l-dimensional parameter to be estimated, and e is an unobserved error. When data are randomly censored, the estimators βn* and gn*forβ and g are obtained by using class K and the least square methods. It is shown that βn* is asymptotically normal and gn* achieves the convergent rate O(n-1/3).

A Censored Nonparametric Software Reliability Model

This paper analyses the effect of censoring on the estimation of failure rate, and presents a framework of a censored nonparametric software reliability model. The model is based on nonparametric testing of failure rate monotonically decreasing and weighted kernel failure rate estimation under the constraint of failure rate monotonically decreasing. Not only does the model have the advantages of little assumptions and weak constraints, but also the residual defects number of the software system can be estimated. The numerical experiment and real data analysis show that the model performs wdl with censored data.

THE NONPARAMETRIC ESTIMATION OF THE NEXT FAILURE TIME

The nonparametric estimation of the next failure time is considered in this paper. The estimator given in the paper has a.s. convergence under some proper conditions. The asymptotic normality of the estimator is also discussed.

Stratified Cox Regression Analysis of Survival under CIMAvax^(■)EGF Vaccine

Background: The Center of Molecular Immunology (CIM) is a center in Cuba devoted to the research, development and manufacturing of biotechnological products. CIMAvax?EGF is a vaccine for the treatment of non-small cell lung cancer patients (NSCL). Purpose: The aim of this work is to evaluate the effects of some potential prognostic factors on the overall survival of patients treated with CIMAvax?EGF vaccine, based on data collected in a phase II and a phase III clinical trials. Methods: The stratified Cox regression model is used to evaluate the effects of these prognostic factors, based on separate analysis for each trial, and on the combined data from both trials. Results: Patients with Performance status 0 or 1, with IV stage of tumor and male under 60 years obtain more benefit in terms of overall survival if they receive CIMAvax?EGF. Conclusions: Vaccinated group has a better performance if patients have a performance status 0 or 1, stage IV and age under 60 years. These prognostic factors influence overall survival in a positive way for those patients that received CIMAvax?EGF.

Reliability Estimators for the Components of Series and Parallel Systems:The Weibull Model

This paper presents a hierarchical Bayesian approach to the estimation of components’ reliability (survival) using a Weibull model for each of them. The proposed method can be used to estimation with general survival censored data, because the estimation of a component’s reliability in a series (parallel) system is equivalent to the estimation of its survival function with right- (left-) censored data. Besides the Weibull parametric model for reliability data, independent gamma distributions are considered at the first hierarchical level for the Weibull parameters and independent uniform distributions over the real line as priors for the parameters of the gammas. In order to evaluate the model, an example and a simulation study are discussed.

An Empirical Likelihood Method in a Partially Linear Single-index Model with Right Censored Data

Empirical-likelihood-based inference for the parameters in a partially linear single-index model with randomly censored data is investigated. We introduce an estimated empirical likelihood for the parameters using a synthetic data approach and show that its limiting distribution is a mixture of central chi-squared distribution. To attack this difficulty we propose an adjusted empirical likelihood to achieve the standard X2-1imit. Furthermore, since the index is of norm 1, we use this constraint to reduce the dimension of parameters, which increases the accuracy of the confidence regions. A simulation study is carried out to compare its finite-sample properties with the existing method. An application to a real data set is illustrated.