Gaming disorder has become a significant issue in mental healthcare. While gaming is an important form of entertainment, excessive gaming may cause serious consequences for players. At present, there are still controv...Gaming disorder has become a significant issue in mental healthcare. While gaming is an important form of entertainment, excessive gaming may cause serious consequences for players. At present, there are still controversies in the academic community concerning the public health problems related to gaming disorder. This article attempts to expound the definition, epidemiology, aetiology, diagnosis, treatment and prevention of gaming disorder, in order to contribute to future conceptualization of gaming disorder.展开更多
In this report, we want to touch upon two aspects of teaching mathematics in middle and high school. The first of them is the eternal question of how to teach, to motivate students and make them involved in the educat...In this report, we want to touch upon two aspects of teaching mathematics in middle and high school. The first of them is the eternal question of how to teach, to motivate students and make them involved in the educational process, particularly in mathematics, where the most important factor is the natural gifts. The second aspect concerns the question which became very urgent in the modern world: what, in fact, we want to teach the students in a world over-saturated with information of any kind. As a result of the information blowup, two aspects emerge. On the one hand, straight passing over the skills and knowledge to the students becomes irrelevant today (just like a teacher or lecturer, merely speaking to an audience, who is not that relevant for young people, accustomed from childhood to perceive information through dynamic color visuals). On the other hand, there is a change in emphasis in the objective function of the educational process from gaining knowledge to acquisition of skills of working with information, consideration and estimation, and choosing of the optimal strategy of a number of possibilities. This trend can be seen in the selection of problems in the international examination PISA (Program for international Student Assessment), in the new curriculum in mathematics and in the selection of problems in the matriculation exams. These considerations (along with others) make teachers took for rtew forms of teaming, more appropriate to the demands of modernity. In this report we suggest the idea of using a mathematical competition called "Mathematical debate" (mathematical fight) as an integral part of the educational process at different levels of learning mathematics, as an appropriate tool.展开更多
viral dance sensation and the debate it sparks.EMERGING f rom a festive wedding ceremony,a dance colloquially known as Kemusan or Subject Three has achieved a meteoric rise to fame across digital platforms in recent w...viral dance sensation and the debate it sparks.EMERGING f rom a festive wedding ceremony,a dance colloquially known as Kemusan or Subject Three has achieved a meteoric rise to fame across digital platforms in recent weeks.In the realm of social media,where trends emerge and vanish like fleeting sparks,the dance craze is currently at the zenith of popularity.展开更多
With the advancement of globalization,university students need not only to master English language skills but also to develop critical thinking and logical expression skills,both of which are crucial for academic and ...With the advancement of globalization,university students need not only to master English language skills but also to develop critical thinking and logical expression skills,both of which are crucial for academic and professional success.As an interactive and structured learning activity,English debates provide an effective platform for enhancing these cognitive and linguistic skills.This study investigates the impact of English debates on students’critical thinking and logical expression skills by analyzing pre-and post-debate assessments,survey data,and in-depth interviews with debate participants.The results indicate significant improvements in critical thinking skills,including argumentation logic,rebuttal techniques,and problem awareness.Students also demonstrated notable progress in organizing and expressing complex ideas logically in English.These findings offer valuable insights for English teaching in higher education,suggesting that debates can serve as an effective pedagogical tool for fostering both language and cognitive development in university students.展开更多
More than 200 scholars,researchers,former government o!cials and party leaders from over 50 countries gathered in the sprawling building of the Chinese Academy of History in Beijing on 20 March for the third Internati...More than 200 scholars,researchers,former government o!cials and party leaders from over 50 countries gathered in the sprawling building of the Chinese Academy of History in Beijing on 20 March for the third International Forum on Democracy:The Shared Human Values.The forum debated the concept of democracy,its trajectories and prospects,and,more importantly,how it can be made to work and deliver tangible results for di"erent countries.展开更多
The koala^1 is a cutie,but does it steal^2 too much of the limelight^3?A new study adds quantitative detail to an ongoing debate over whether such"conservation mascots^4"receive publicity and funding to the detrime...The koala^1 is a cutie,but does it steal^2 too much of the limelight^3?A new study adds quantitative detail to an ongoing debate over whether such"conservation mascots^4"receive publicity and funding to the detriment of^5 animals typically deemed less attractive.展开更多
Rectal carcinoma represents the 30% of all colorectal cancers, with about 40000 new cases/years. In the past two decades, the management of rectal cancer has made important progress, highlighting the main role of a mu...Rectal carcinoma represents the 30% of all colorectal cancers, with about 40000 new cases/years. In the past two decades, the management of rectal cancer has made important progress, highlighting the main role of a multimodality strategy approach, combining surgery, radiation therapy and chemotherapy. Nowadays, surgery remains the primary treatment and neoadjuvant chemoradiotherapy, based on fluoropyrimidine(5-FU) continuous infusion, is considered the standard in locally advanced rectal carcinoma. The aim is to reduce the incidence of local recurrence and to perform a conservative surgery. To improve these purposes different drugs combination have been tested in the neo-adjuvant setting. At American Society of Clinical Oncology 2014 an important abstract was presented focusing on the role of adding oxaliplatin to concomitant treatment, in patients with locally advanced rectal carcinoma. Rodel et al reported on the CAO/ARO/AIO-04 randomized phase Ⅲ trial that compared standard treatment with 5-FU and radiation therapy, to oxaliplatin plus 5-FU inassociation with radiation therapy. The addition of oxaliplatin to the neo-adjuvant treatment has been shown to improve disease-free survival from 71.2% to 75.9%(P = 0.03). This editorial was planned to clarify the optimal treatment in patients with locally advanced rectal cancer, considering the results from CAO/ARO/AIO-04 study.展开更多
Through our newly-developed "chemical vapor deposition integrated process (ISVD-IP)'" using carbon OlOXlae (t..u2) as me raw matenal and only carbon source introduced, CO2 could be catalytically activated and c...Through our newly-developed "chemical vapor deposition integrated process (ISVD-IP)'" using carbon OlOXlae (t..u2) as me raw matenal and only carbon source introduced, CO2 could be catalytically activated and converted to a new solid-form product, i.e., carbon nanotubes (CO2-derived) at a quite high yield (the single-pass carbon yield in the solid-form carbon-product produced from CO2 catalytic capture and conversion was more than 30% at a single-pass carbon-base). For comparison, when only pure carbon dioxide was introduced using the conventional CVD method without integrated process, no solid-form carbon-material product could be formed. In the addition of saturated steam at room temperature in the feed for CVD, there were much more end-opening carbon nano-tubes produced, at a slightly higher carbon yield. These inspiring works opened a remarkable and alternative new approach for carbon dioxide catalytic capture to solid-form product, comparing with that of CO2 sequestration (CCS) or CO2 mineralization (solidification), etc. As a result, there was much less body volume and almost no greenhouse effect for this solid-form carbon-material than those of primitive carbon dioxide.展开更多
Following publication of NASCIS Ⅱ, methylprednisolone sodium succinate(MPSS) was hailed as a breakthrough for patients with acute spinal cord injury(SCI). MPSS use for SCI has since become very controversial and ...Following publication of NASCIS Ⅱ, methylprednisolone sodium succinate(MPSS) was hailed as a breakthrough for patients with acute spinal cord injury(SCI). MPSS use for SCI has since become very controversial and it is our opinion that additional evidence is unlikely to break the stalemate amongst clinicians. Patient opinion has the potential to break this stalemate and we review our recent findings which reported that spinal cord injured patients informed of the risks and benefits of MPSS reported a preference for MPSS administration. We discuss the implications of the current MPSS debate on translational research and seek to address some misconceptions which have evolved. As science has failed to resolve the MPSS debate we argue that the debate is an increasingly philosophical one. We question whether SCI might be viewed as a serious condition like cancer where serious side effects of therapeutics are tolerated even when benefits may be small. We also draw attention to the similarity between the side effects of MPSS and isotretinoin which is prescribed for the cosmetic disorder acne vulgaris. Ultimately we question how patient autonomy should be weighed in the context of current SCI guidelines and MPSS's status as a historical standard of care.展开更多
Barefoot running has been around for millions of years,and it is safe to presume that for most of that time,the practice occasioned little interest.Our ancestors ran barefoot because they had no shoes.When footwear wa...Barefoot running has been around for millions of years,and it is safe to presume that for most of that time,the practice occasioned little interest.Our ancestors ran barefoot because they had no shoes.When footwear was first invented during the last 40,000 years (no doubt at different times and in different places),shoes were by necessity minimal-essentially sandals and moccasins-designed to protect the sole of the foot but lacking any of the sophisticated features and materials present in modem running shoes such as elevated cushioned heels,arch supports,and toe springs.Most of these features were invented in the 1970s,and they quickly became more popular and sophisticated as running underwent a worldwide boom.Today,the vast majority of runners think it is normal to wear cushioned running shoes,and would never dream of running without them.展开更多
A piece of equipment designed under a multi-disciplinary project in Shandong University of Science and Technology is described.The purpose is to indicate speech-time status to speakers in debates by presenting a three...A piece of equipment designed under a multi-disciplinary project in Shandong University of Science and Technology is described.The purpose is to indicate speech-time status to speakers in debates by presenting a three-light output The speech length may be programmed by the user with a combination of buttons and LCD display.The system is portable and microcontroller-based,using on-chip timers for accurate measurement of durations.展开更多
The recent and ongoing debate about the character of(not only)ancient economies reveals that the traditional rivalry between‘primitivist-substantivist’and‘modernist-formalist’views has defi nitely come to an end a...The recent and ongoing debate about the character of(not only)ancient economies reveals that the traditional rivalry between‘primitivist-substantivist’and‘modernist-formalist’views has defi nitely come to an end although a more or less conscious afterlife and shaping of minds still exists.1As such。展开更多
About,of,on是几个常用介词.当然,除了of外,about和on还可作副词使用.在英语里,当它们作介词用时,其表达的意义很宽,使用的范围也很广.本文仅就它们作“论及、提及、说及、关于”等意义时的用法及区别作个讨论。 先看中学课本里出现的...About,of,on是几个常用介词.当然,除了of外,about和on还可作副词使用.在英语里,当它们作介词用时,其表达的意义很宽,使用的范围也很广.本文仅就它们作“论及、提及、说及、关于”等意义时的用法及区别作个讨论。 先看中学课本里出现的几个句子: a) In one of his books, Marx gave some advice on how to learn a foreign language. b) Once Lu Xun spoke to the youth about the study of foreign languages. c) Do you know the essays of Francis Bacon, who lived about the same time as shakespeare? They are full of good advice about reading. Here is a bit from the essay "of Studies". 从上述例句中可以看出about、of、on都是作“关于、论及、提及”等解释.下面就它们之间的用法及区别分述如下:展开更多
A growing world population coupled with changing diet is projected to increase demand for food production by 70% by 2050. Helping farmers lose less of their crops will be a key factor in promoting food security. In ad...A growing world population coupled with changing diet is projected to increase demand for food production by 70% by 2050. Helping farmers lose less of their crops will be a key factor in promoting food security. In addition to pesticides GM crops will continue to be a vital tool in the diverse range of technologies that can maintain and improve living standards for the people of the world. The EU is dependent for 65% on imports of protein-rich feedstuffs for which there are no substitutes in the short term. The EU livestock sector uses imported soybean, soybean meal and maize by-products as animal feed. Without an adequate supply of these feed ingredients, the EU’s livestock production will loose competitiveness. However, demands from the EU differ to those from third countries with respect to the GM varieties grown, and what are authorised for import into the EU. The risk that supplies of soya products and maize by-products could be affected by the low-level presence of non-EU approved GM material has not been fully resolved as the EU has allowed just a 0.1% tolerance for this plus 0.05% tolerance for measuring uncertainty. This could cause supply problems for the animal feed industry, and ultimately supply of food to consumers. The importance of the EU market and EU requirements for the major soybean and maize exporter countries is declining over time and it is becoming increasingly difficult and costly to maintain a non-GM supply chain in the EU. Food companies and supermarkets will struggle to stay GM-free. EU member states dependent on imports will be forced to deal with more GM presence in their chain. Market forces are forcing governments to authorize products more efficiently, develop tolerance policies or tolerate unapproved varieties in their imports.展开更多
Parkinson’s disease(PD)is a heterogeneous multifactorial disorder and,during the last years,new scientific evidence has supported this concept.The principal hallmarks of PD are the loss of dopaminergic neurons in the...Parkinson’s disease(PD)is a heterogeneous multifactorial disorder and,during the last years,new scientific evidence has supported this concept.The principal hallmarks of PD are the loss of dopaminergic neurons in the substantia nigra pars compacta and the aggregation of misfolded alpha-synuclein(α-syn).展开更多
Letters to the editor can provide useful scientific information and evaluation of published work as well as acting as an additional level of peer review.Furthermore,letters are good reading material,especially if they...Letters to the editor can provide useful scientific information and evaluation of published work as well as acting as an additional level of peer review.Furthermore,letters are good reading material,especially if they involve a debate between authors.Finally,letters are relatively short.Therefore,inexperienced career researchers can use such an opportunity to practice putting together a cogent argument.However,it is far from an ideal situation if letters are the only(or main)type of article on which to base an academic career.展开更多
基金grants from the National Key R&D Program of China(2017YFC1310400)the National Natural Science Foundation of China(81371465 and 81671324).
文摘Gaming disorder has become a significant issue in mental healthcare. While gaming is an important form of entertainment, excessive gaming may cause serious consequences for players. At present, there are still controversies in the academic community concerning the public health problems related to gaming disorder. This article attempts to expound the definition, epidemiology, aetiology, diagnosis, treatment and prevention of gaming disorder, in order to contribute to future conceptualization of gaming disorder.
文摘In this report, we want to touch upon two aspects of teaching mathematics in middle and high school. The first of them is the eternal question of how to teach, to motivate students and make them involved in the educational process, particularly in mathematics, where the most important factor is the natural gifts. The second aspect concerns the question which became very urgent in the modern world: what, in fact, we want to teach the students in a world over-saturated with information of any kind. As a result of the information blowup, two aspects emerge. On the one hand, straight passing over the skills and knowledge to the students becomes irrelevant today (just like a teacher or lecturer, merely speaking to an audience, who is not that relevant for young people, accustomed from childhood to perceive information through dynamic color visuals). On the other hand, there is a change in emphasis in the objective function of the educational process from gaining knowledge to acquisition of skills of working with information, consideration and estimation, and choosing of the optimal strategy of a number of possibilities. This trend can be seen in the selection of problems in the international examination PISA (Program for international Student Assessment), in the new curriculum in mathematics and in the selection of problems in the matriculation exams. These considerations (along with others) make teachers took for rtew forms of teaming, more appropriate to the demands of modernity. In this report we suggest the idea of using a mathematical competition called "Mathematical debate" (mathematical fight) as an integral part of the educational process at different levels of learning mathematics, as an appropriate tool.
文摘viral dance sensation and the debate it sparks.EMERGING f rom a festive wedding ceremony,a dance colloquially known as Kemusan or Subject Three has achieved a meteoric rise to fame across digital platforms in recent weeks.In the realm of social media,where trends emerge and vanish like fleeting sparks,the dance craze is currently at the zenith of popularity.
文摘With the advancement of globalization,university students need not only to master English language skills but also to develop critical thinking and logical expression skills,both of which are crucial for academic and professional success.As an interactive and structured learning activity,English debates provide an effective platform for enhancing these cognitive and linguistic skills.This study investigates the impact of English debates on students’critical thinking and logical expression skills by analyzing pre-and post-debate assessments,survey data,and in-depth interviews with debate participants.The results indicate significant improvements in critical thinking skills,including argumentation logic,rebuttal techniques,and problem awareness.Students also demonstrated notable progress in organizing and expressing complex ideas logically in English.These findings offer valuable insights for English teaching in higher education,suggesting that debates can serve as an effective pedagogical tool for fostering both language and cognitive development in university students.
文摘More than 200 scholars,researchers,former government o!cials and party leaders from over 50 countries gathered in the sprawling building of the Chinese Academy of History in Beijing on 20 March for the third International Forum on Democracy:The Shared Human Values.The forum debated the concept of democracy,its trajectories and prospects,and,more importantly,how it can be made to work and deliver tangible results for di"erent countries.
文摘The koala^1 is a cutie,but does it steal^2 too much of the limelight^3?A new study adds quantitative detail to an ongoing debate over whether such"conservation mascots^4"receive publicity and funding to the detriment of^5 animals typically deemed less attractive.
文摘Rectal carcinoma represents the 30% of all colorectal cancers, with about 40000 new cases/years. In the past two decades, the management of rectal cancer has made important progress, highlighting the main role of a multimodality strategy approach, combining surgery, radiation therapy and chemotherapy. Nowadays, surgery remains the primary treatment and neoadjuvant chemoradiotherapy, based on fluoropyrimidine(5-FU) continuous infusion, is considered the standard in locally advanced rectal carcinoma. The aim is to reduce the incidence of local recurrence and to perform a conservative surgery. To improve these purposes different drugs combination have been tested in the neo-adjuvant setting. At American Society of Clinical Oncology 2014 an important abstract was presented focusing on the role of adding oxaliplatin to concomitant treatment, in patients with locally advanced rectal carcinoma. Rodel et al reported on the CAO/ARO/AIO-04 randomized phase Ⅲ trial that compared standard treatment with 5-FU and radiation therapy, to oxaliplatin plus 5-FU inassociation with radiation therapy. The addition of oxaliplatin to the neo-adjuvant treatment has been shown to improve disease-free survival from 71.2% to 75.9%(P = 0.03). This editorial was planned to clarify the optimal treatment in patients with locally advanced rectal cancer, considering the results from CAO/ARO/AIO-04 study.
基金the National 973 Program of Ministry of Sciences and Technologies of China(2011CB201202)the National Natural Science Foundation of China(20776089)
文摘Through our newly-developed "chemical vapor deposition integrated process (ISVD-IP)'" using carbon OlOXlae (t..u2) as me raw matenal and only carbon source introduced, CO2 could be catalytically activated and converted to a new solid-form product, i.e., carbon nanotubes (CO2-derived) at a quite high yield (the single-pass carbon yield in the solid-form carbon-product produced from CO2 catalytic capture and conversion was more than 30% at a single-pass carbon-base). For comparison, when only pure carbon dioxide was introduced using the conventional CVD method without integrated process, no solid-form carbon-material product could be formed. In the addition of saturated steam at room temperature in the feed for CVD, there were much more end-opening carbon nano-tubes produced, at a slightly higher carbon yield. These inspiring works opened a remarkable and alternative new approach for carbon dioxide catalytic capture to solid-form product, comparing with that of CO2 sequestration (CCS) or CO2 mineralization (solidification), etc. As a result, there was much less body volume and almost no greenhouse effect for this solid-form carbon-material than those of primitive carbon dioxide.
文摘Following publication of NASCIS Ⅱ, methylprednisolone sodium succinate(MPSS) was hailed as a breakthrough for patients with acute spinal cord injury(SCI). MPSS use for SCI has since become very controversial and it is our opinion that additional evidence is unlikely to break the stalemate amongst clinicians. Patient opinion has the potential to break this stalemate and we review our recent findings which reported that spinal cord injured patients informed of the risks and benefits of MPSS reported a preference for MPSS administration. We discuss the implications of the current MPSS debate on translational research and seek to address some misconceptions which have evolved. As science has failed to resolve the MPSS debate we argue that the debate is an increasingly philosophical one. We question whether SCI might be viewed as a serious condition like cancer where serious side effects of therapeutics are tolerated even when benefits may be small. We also draw attention to the similarity between the side effects of MPSS and isotretinoin which is prescribed for the cosmetic disorder acne vulgaris. Ultimately we question how patient autonomy should be weighed in the context of current SCI guidelines and MPSS's status as a historical standard of care.
文摘Barefoot running has been around for millions of years,and it is safe to presume that for most of that time,the practice occasioned little interest.Our ancestors ran barefoot because they had no shoes.When footwear was first invented during the last 40,000 years (no doubt at different times and in different places),shoes were by necessity minimal-essentially sandals and moccasins-designed to protect the sole of the foot but lacking any of the sophisticated features and materials present in modem running shoes such as elevated cushioned heels,arch supports,and toe springs.Most of these features were invented in the 1970s,and they quickly became more popular and sophisticated as running underwent a worldwide boom.Today,the vast majority of runners think it is normal to wear cushioned running shoes,and would never dream of running without them.
文摘A piece of equipment designed under a multi-disciplinary project in Shandong University of Science and Technology is described.The purpose is to indicate speech-time status to speakers in debates by presenting a three-light output The speech length may be programmed by the user with a combination of buttons and LCD display.The system is portable and microcontroller-based,using on-chip timers for accurate measurement of durations.
文摘The recent and ongoing debate about the character of(not only)ancient economies reveals that the traditional rivalry between‘primitivist-substantivist’and‘modernist-formalist’views has defi nitely come to an end although a more or less conscious afterlife and shaping of minds still exists.1As such。
文摘About,of,on是几个常用介词.当然,除了of外,about和on还可作副词使用.在英语里,当它们作介词用时,其表达的意义很宽,使用的范围也很广.本文仅就它们作“论及、提及、说及、关于”等意义时的用法及区别作个讨论。 先看中学课本里出现的几个句子: a) In one of his books, Marx gave some advice on how to learn a foreign language. b) Once Lu Xun spoke to the youth about the study of foreign languages. c) Do you know the essays of Francis Bacon, who lived about the same time as shakespeare? They are full of good advice about reading. Here is a bit from the essay "of Studies". 从上述例句中可以看出about、of、on都是作“关于、论及、提及”等解释.下面就它们之间的用法及区别分述如下:
文摘A growing world population coupled with changing diet is projected to increase demand for food production by 70% by 2050. Helping farmers lose less of their crops will be a key factor in promoting food security. In addition to pesticides GM crops will continue to be a vital tool in the diverse range of technologies that can maintain and improve living standards for the people of the world. The EU is dependent for 65% on imports of protein-rich feedstuffs for which there are no substitutes in the short term. The EU livestock sector uses imported soybean, soybean meal and maize by-products as animal feed. Without an adequate supply of these feed ingredients, the EU’s livestock production will loose competitiveness. However, demands from the EU differ to those from third countries with respect to the GM varieties grown, and what are authorised for import into the EU. The risk that supplies of soya products and maize by-products could be affected by the low-level presence of non-EU approved GM material has not been fully resolved as the EU has allowed just a 0.1% tolerance for this plus 0.05% tolerance for measuring uncertainty. This could cause supply problems for the animal feed industry, and ultimately supply of food to consumers. The importance of the EU market and EU requirements for the major soybean and maize exporter countries is declining over time and it is becoming increasingly difficult and costly to maintain a non-GM supply chain in the EU. Food companies and supermarkets will struggle to stay GM-free. EU member states dependent on imports will be forced to deal with more GM presence in their chain. Market forces are forcing governments to authorize products more efficiently, develop tolerance policies or tolerate unapproved varieties in their imports.
基金supported by a grant from NYU Grossman School of Medicine and The Marlene and Paolo Fresco Institute for Parkinson’s and Movement Disorders, which was made possible with support from Marlene and Paolo Fresco (to AC)
文摘Parkinson’s disease(PD)is a heterogeneous multifactorial disorder and,during the last years,new scientific evidence has supported this concept.The principal hallmarks of PD are the loss of dopaminergic neurons in the substantia nigra pars compacta and the aggregation of misfolded alpha-synuclein(α-syn).
文摘Letters to the editor can provide useful scientific information and evaluation of published work as well as acting as an additional level of peer review.Furthermore,letters are good reading material,especially if they involve a debate between authors.Finally,letters are relatively short.Therefore,inexperienced career researchers can use such an opportunity to practice putting together a cogent argument.However,it is far from an ideal situation if letters are the only(or main)type of article on which to base an academic career.