This experimental study is a contribution to the search for solutions to reduce indoor heat gain through sheet metal roofing in hot weather. It has evaluated the thermal impact of two different sheet metal roofs insid...This experimental study is a contribution to the search for solutions to reduce indoor heat gain through sheet metal roofing in hot weather. It has evaluated the thermal impact of two different sheet metal roofs inside of two identical test buildings in sunny weather and cloudy weather conditions. Test building 1 has a single sheet corrugated roof and the building 2 is covered with roof made from top to bottom with corrugated sheet metal, a 12 mm thick serpentine copper tube in which water is circulated, a sheet of aluminium foil acting as a heat reflector, a 4 cm thick polystyrene panel and a 1.5 cm thick plywood. A maximum reduction of 15.1˚C in the temperature of the inner face of the test Building 2 roof was obtained comparatively to the temperature of the inner face of the test Building 1 roof consisting of a single sheet of metal at the warmest hours. In addition, the simple corrugated sheet metal roof of the test building generates high and varied temperatures inside the building. Whereas the proposed heat recovery roof favours low and relatively uniform temperatures inside the building. The proposed sheet metal roof construction technique is very effective in reducing the heat gain through the roof considerably;thus improving the thermal comfort inside sheet metal roofed dwellings. Hot water has been produced by recovering heat from the metal sheet of the roof of test building 2. The temperature of the hot water produced reached of 39˚C. This study could be also an alternative for the reduction of energy consumption due to the use of mechanical means for cooling of sheet metal roofed houses and the reduction of the use of fossil fuels for domestic hot water production.展开更多
现代的大型复杂结构,如大坝、高层建筑、桥梁及海洋平台等,处于复杂的环境载荷作用下,这些环境载荷往往是无法测量的。在仅有输出响应时,应用随机减量法RDT获得自由衰减响应信号,而后用时域复指数拟合法、ITD法、特征系统实现算法ERA等...现代的大型复杂结构,如大坝、高层建筑、桥梁及海洋平台等,处于复杂的环境载荷作用下,这些环境载荷往往是无法测量的。在仅有输出响应时,应用随机减量法RDT获得自由衰减响应信号,而后用时域复指数拟合法、ITD法、特征系统实现算法ERA等算法获得结构的模态参数是一种有效的方法。但在数据量有限时,随机减量函数的平均次数过少,导致RD函数的收敛性较差。为此提出了利用Vector Random Decrement技术(VRDT)提取自由衰减响应信号,而后利用特征系统实现算法ERA求得模态参数的方法,新算法能够有效地提高模态参数识别精度。数值算例验证了所提算法的有效性。展开更多
目的:研究不同剂量依巴斯汀联合复方甘草酸苷递减疗法治疗慢性荨麻疹的临床应用效果。方法:选取2022年1月至2023年9月我院就诊的44例慢性荨麻疹患者为研究对象。按照不同治疗方案分为对照组和观察组,各22例。对照组采用10 mg依巴斯汀片...目的:研究不同剂量依巴斯汀联合复方甘草酸苷递减疗法治疗慢性荨麻疹的临床应用效果。方法:选取2022年1月至2023年9月我院就诊的44例慢性荨麻疹患者为研究对象。按照不同治疗方案分为对照组和观察组,各22例。对照组采用10 mg依巴斯汀片,观察组采用20 mg依巴斯汀,两组均联合复方甘草酸苷递减疗法治疗。比较两组治疗前后临床症状积分、血液学指标[血清白介素-17(Interleukin-17,IL-17)、白介素-25(Interleukin-25,IL-25)、白介素-33(Interleukin,33,IL-33)]、T淋巴细胞计数[辅助性T细胞(Helper T cell,CD4^(+))、细胞毒性T细胞(Cytotoxic T cell,CD8^(+))]水平、临床疗效及用药不良反应发生率。结果:治疗后,观察组临床症状积分总有效率均高于对照组(P<0.05);观察组总有效率均高于对照组(P<0.05);治疗后,观察组IL-17、IL-25、IL-33及CD8^(+)均低于对照组,CD4^(+)高于对照组(P<0.05);两组不良反应发生率无显著差异。结论:20 mg依巴斯汀联合复方甘草酸苷递减疗法可以更有效缓解慢性荨麻疹患者临床症状,降低血清IL-17、IL-25、IL-33水平,改善机体免疫功能,且较为安全。展开更多
The dying-back hypothesis holds that the damage to neuromuscular junctions and distal axons in amyotrophic lateral sclerosis occurs at the earliest stage of the disease.Previous basic studies have confirmed early dama...The dying-back hypothesis holds that the damage to neuromuscular junctions and distal axons in amyotrophic lateral sclerosis occurs at the earliest stage of the disease.Previous basic studies have confirmed early damage to neuromuscular junctions,but it is difficult to obtain such evidence directly in clinical practice.In this prospective cross-sectional study,we recruited 22 patients with early amyotrophic lateral sclerosis with disease duration < 12 months and with clinical symptoms limited to the upper limbs.We also recruited 32 healthy controls.Repetitive nerve stimulation was performed,and patients were followed for 12 months.We found a significant change in the response to repetitive nerve stimulation in amyotrophic lateral sclerosis patients without spontaneous electromyographic activity.Patients that were prone to denervation had an increased decrement response of target muscles after repetitive nerve stimulation.These results suggest that changes in response to repetitive nerve stimulation may occur before denervation in amyotrophic lateral sclerosis patients.The damage to lower motor neurons is more obvious in patients with a higher percentage of repetitive never stimulation-related amplitude decrements.This study was approved by the Institutional Ethics Committee of Peking University Third Hospital(approval No.M2017198) on August 24,2017.展开更多
Surface potential is an important parameter related to the physical and chemical properties of charged particles. A simple analytical model for the estimation of surface potential is established based on the Poisson–...Surface potential is an important parameter related to the physical and chemical properties of charged particles. A simple analytical model for the estimation of surface potential is established based on the Poisson–Boltzmann theory with the consideration of the dielectric decrement in mixed electrolyte. The analytical relationships between surface potential and charge density are derived in different mixed electrolytes with monovalent and bivalent ions. The dielectric decrease on the charged surface strongly affects the surface potential at a high charge density with different ion strengths and concentration ratios of counter-ions. The surface potential based on the Gouy–Chapman model is underestimated because of the dielectric decrement on the surface. The diffuse layer can be regarded as a continuous uniform medium only when the surface charge density is lower than 0.3 C·m-2. However, the surface charge densities of many materials in practical applications are higher than 0.3 C·m-2. The new model for the estimation of surface potential can return to the results obtained based on the Gouy–Chapman model at a low charge density. Therefore, it is implied that the established model that considers the dielectric decrement is valid and widely applicable.展开更多
The observation of a left sided accessory pathway with decremental properties is rare. We describe the behaviour of one of these pathways which was characterized by the presence of retrograde conduction (not previousl...The observation of a left sided accessory pathway with decremental properties is rare. We describe the behaviour of one of these pathways which was characterized by the presence of retrograde conduction (not previously reported) and thus inducibility of atrio-ventricular orthodromic reentrant tachycardia.展开更多
Frequent item sets mining plays an important role in association rules mining. A variety of algorithms for finding frequent item sets in very large transaction databases have been developed. Although many techniques w...Frequent item sets mining plays an important role in association rules mining. A variety of algorithms for finding frequent item sets in very large transaction databases have been developed. Although many techniques were proposed for maintenance of the discovered rules when new transactions are added, little work is done for maintaining the discovered rules when some transactions are deleted from the database. Updates are fundamental aspect of data management. In this paper, a decremental association rules mining algorithm is present for updating the discovered association rules when some transactions are removed from the original data set. Extensive experiments were conducted to evaluate the performance of the proposed algorithm. The results show that the proposed algorithm is efficient and outperforms other well-known algorithms.展开更多
文摘This experimental study is a contribution to the search for solutions to reduce indoor heat gain through sheet metal roofing in hot weather. It has evaluated the thermal impact of two different sheet metal roofs inside of two identical test buildings in sunny weather and cloudy weather conditions. Test building 1 has a single sheet corrugated roof and the building 2 is covered with roof made from top to bottom with corrugated sheet metal, a 12 mm thick serpentine copper tube in which water is circulated, a sheet of aluminium foil acting as a heat reflector, a 4 cm thick polystyrene panel and a 1.5 cm thick plywood. A maximum reduction of 15.1˚C in the temperature of the inner face of the test Building 2 roof was obtained comparatively to the temperature of the inner face of the test Building 1 roof consisting of a single sheet of metal at the warmest hours. In addition, the simple corrugated sheet metal roof of the test building generates high and varied temperatures inside the building. Whereas the proposed heat recovery roof favours low and relatively uniform temperatures inside the building. The proposed sheet metal roof construction technique is very effective in reducing the heat gain through the roof considerably;thus improving the thermal comfort inside sheet metal roofed dwellings. Hot water has been produced by recovering heat from the metal sheet of the roof of test building 2. The temperature of the hot water produced reached of 39˚C. This study could be also an alternative for the reduction of energy consumption due to the use of mechanical means for cooling of sheet metal roofed houses and the reduction of the use of fossil fuels for domestic hot water production.
文摘现代的大型复杂结构,如大坝、高层建筑、桥梁及海洋平台等,处于复杂的环境载荷作用下,这些环境载荷往往是无法测量的。在仅有输出响应时,应用随机减量法RDT获得自由衰减响应信号,而后用时域复指数拟合法、ITD法、特征系统实现算法ERA等算法获得结构的模态参数是一种有效的方法。但在数据量有限时,随机减量函数的平均次数过少,导致RD函数的收敛性较差。为此提出了利用Vector Random Decrement技术(VRDT)提取自由衰减响应信号,而后利用特征系统实现算法ERA求得模态参数的方法,新算法能够有效地提高模态参数识别精度。数值算例验证了所提算法的有效性。
文摘目的:研究不同剂量依巴斯汀联合复方甘草酸苷递减疗法治疗慢性荨麻疹的临床应用效果。方法:选取2022年1月至2023年9月我院就诊的44例慢性荨麻疹患者为研究对象。按照不同治疗方案分为对照组和观察组,各22例。对照组采用10 mg依巴斯汀片,观察组采用20 mg依巴斯汀,两组均联合复方甘草酸苷递减疗法治疗。比较两组治疗前后临床症状积分、血液学指标[血清白介素-17(Interleukin-17,IL-17)、白介素-25(Interleukin-25,IL-25)、白介素-33(Interleukin,33,IL-33)]、T淋巴细胞计数[辅助性T细胞(Helper T cell,CD4^(+))、细胞毒性T细胞(Cytotoxic T cell,CD8^(+))]水平、临床疗效及用药不良反应发生率。结果:治疗后,观察组临床症状积分总有效率均高于对照组(P<0.05);观察组总有效率均高于对照组(P<0.05);治疗后,观察组IL-17、IL-25、IL-33及CD8^(+)均低于对照组,CD4^(+)高于对照组(P<0.05);两组不良反应发生率无显著差异。结论:20 mg依巴斯汀联合复方甘草酸苷递减疗法可以更有效缓解慢性荨麻疹患者临床症状,降低血清IL-17、IL-25、IL-33水平,改善机体免疫功能,且较为安全。
文摘The dying-back hypothesis holds that the damage to neuromuscular junctions and distal axons in amyotrophic lateral sclerosis occurs at the earliest stage of the disease.Previous basic studies have confirmed early damage to neuromuscular junctions,but it is difficult to obtain such evidence directly in clinical practice.In this prospective cross-sectional study,we recruited 22 patients with early amyotrophic lateral sclerosis with disease duration < 12 months and with clinical symptoms limited to the upper limbs.We also recruited 32 healthy controls.Repetitive nerve stimulation was performed,and patients were followed for 12 months.We found a significant change in the response to repetitive nerve stimulation in amyotrophic lateral sclerosis patients without spontaneous electromyographic activity.Patients that were prone to denervation had an increased decrement response of target muscles after repetitive nerve stimulation.These results suggest that changes in response to repetitive nerve stimulation may occur before denervation in amyotrophic lateral sclerosis patients.The damage to lower motor neurons is more obvious in patients with a higher percentage of repetitive never stimulation-related amplitude decrements.This study was approved by the Institutional Ethics Committee of Peking University Third Hospital(approval No.M2017198) on August 24,2017.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.41501240,41530855,41501241,and 41877026)the Natural Science Foundation of Chongqing CSTC(Grant No.cstc2018jcyjAX0318)the Fundamental Research Funds for the Central Universities,China(Grant No.XDJK2017B029)
文摘Surface potential is an important parameter related to the physical and chemical properties of charged particles. A simple analytical model for the estimation of surface potential is established based on the Poisson–Boltzmann theory with the consideration of the dielectric decrement in mixed electrolyte. The analytical relationships between surface potential and charge density are derived in different mixed electrolytes with monovalent and bivalent ions. The dielectric decrease on the charged surface strongly affects the surface potential at a high charge density with different ion strengths and concentration ratios of counter-ions. The surface potential based on the Gouy–Chapman model is underestimated because of the dielectric decrement on the surface. The diffuse layer can be regarded as a continuous uniform medium only when the surface charge density is lower than 0.3 C·m-2. However, the surface charge densities of many materials in practical applications are higher than 0.3 C·m-2. The new model for the estimation of surface potential can return to the results obtained based on the Gouy–Chapman model at a low charge density. Therefore, it is implied that the established model that considers the dielectric decrement is valid and widely applicable.
文摘The observation of a left sided accessory pathway with decremental properties is rare. We describe the behaviour of one of these pathways which was characterized by the presence of retrograde conduction (not previously reported) and thus inducibility of atrio-ventricular orthodromic reentrant tachycardia.
文摘Frequent item sets mining plays an important role in association rules mining. A variety of algorithms for finding frequent item sets in very large transaction databases have been developed. Although many techniques were proposed for maintenance of the discovered rules when new transactions are added, little work is done for maintaining the discovered rules when some transactions are deleted from the database. Updates are fundamental aspect of data management. In this paper, a decremental association rules mining algorithm is present for updating the discovered association rules when some transactions are removed from the original data set. Extensive experiments were conducted to evaluate the performance of the proposed algorithm. The results show that the proposed algorithm is efficient and outperforms other well-known algorithms.
