Threshold-Based Software-Defined Networking(SDN)Solution for Healthcare Systems against Intrusion Attacks

The healthcare sector holds valuable and sensitive data.The amount of this data and the need to handle,exchange,and protect it,has been increasing at a fast pace.Due to their nature,software-defined networks(SDNs)are widely used in healthcare systems,as they ensure effective resource utilization,safety,great network management,and monitoring.In this sector,due to the value of thedata,SDNs faceamajor challengeposed byawide range of attacks,such as distributed denial of service(DDoS)and probe attacks.These attacks reduce network performance,causing the degradation of different key performance indicators(KPIs)or,in the worst cases,a network failure which can threaten human lives.This can be significant,especially with the current expansion of portable healthcare that supports mobile and wireless devices for what is called mobile health,or m-health.In this study,we examine the effectiveness of using SDNs for defense against DDoS,as well as their effects on different network KPIs under various scenarios.We propose a threshold-based DDoS classifier(TBDC)technique to classify DDoS attacks in healthcare SDNs,aiming to block traffic considered a hazard in the form of a DDoS attack.We then evaluate the accuracy and performance of the proposed TBDC approach.Our technique shows outstanding performance,increasing the mean throughput by 190.3%,reducing the mean delay by 95%,and reducing packet loss by 99.7%relative to normal,with DDoS attack traffic.

Open-Source Software Defined Networking Controllers:State-of-the-Art,Challenges and Solutions for Future Network Providers

Software Defined Networking(SDN)is programmable by separation of forwarding control through the centralization of the controller.The controller plays the role of the‘brain’that dictates the intelligent part of SDN technology.Various versions of SDN controllers exist as a response to the diverse demands and functions expected of them.There are several SDN controllers available in the open market besides a large number of commercial controllers;some are developed tomeet carrier-grade service levels and one of the recent trends in open-source SDN controllers is the Open Network Operating System(ONOS).This paper presents a comparative study between open source SDN controllers,which are known as Network Controller Platform(NOX),Python-based Network Controller(POX),component-based SDN framework(Ryu),Java-based OpenFlow controller(Floodlight),OpenDayLight(ODL)and ONOS.The discussion is further extended into ONOS architecture,as well as,the evolution of ONOS controllers.This article will review use cases based on ONOS controllers in several application deployments.Moreover,the opportunities and challenges of open source SDN controllers will be discussed,exploring carriergrade ONOS for future real-world deployments,ONOS unique features and identifying the suitable choice of SDN controller for service providers.In addition,we attempt to provide answers to several critical questions relating to the implications of the open-source nature of SDN controllers regarding vendor lock-in,interoperability,and standards compliance,Similarly,real-world use cases of organizations using open-source SDN are highlighted and how the open-source community contributes to the development of SDN controllers.Furthermore,challenges faced by open-source projects,and considerations when choosing an open-source SDN controller are underscored.Then the role of Artificial Intelligence(AI)and Machine Learning(ML)in the evolution of open-source SDN controllers in light of recent research is indicated.In addition,the challenges and limitations associated with deploying open-source SDN controllers in production networks,how can they be mitigated,and finally how opensource SDN controllers handle network security and ensure that network configurations and policies are robust and resilient are presented.Potential opportunities and challenges for future Open SDN deployment are outlined to conclude the article.

Software defined satellite networks:A survey

In recent years,satellite networks have been proposed as an essential part of next-generation mobile communication systems.Software defined networking techniques are introduced in satellite networks to handle the growing challenges induced by time-varying topology,intermittent inter-satellite link and dramatically increased satellite constellation size.This survey covers the latest progress of software defined satellite networks,including key techniques,existing solutions,challenges,opportunities,and simulation tools.To the best of our knowledge,this paper is the most comprehensive survey that covers the latest progress of software defined satellite networks.An open GitHub repository is further created where the latest papers on this topic will be tracked and updated periodically.Compared with these existing surveys,this survey contributes from three aspects:(1)an up-to-date SDN-oriented review for the latest progress of key techniques and solutions in software defined satellite networks;(2)an inspiring summary of existing challenges,new research opportunities and publicly available simulation tools for follow-up studies;(3)an effort of building a public repository to track new results.

Deployment Strategy for Multiple Controllers Based on the Aviation On-Board Software-Defined Data Link Network

In light of the escalating demand and intricacy of services in contemporary terrestrial,maritime,and aerial combat operations,there is a compelling need for enhanced service quality and efficiency in airborne cluster communication networks.Software-Defined Networking(SDN)proffers a viable solution for the multifaceted task of cooperative communication transmission and management across different operational domains within complex combat contexts,due to its intrinsic ability to flexibly allocate and centrally administer network resources.This study pivots around the optimization of SDN controller deployment within airborne data link clusters.A collaborative multi-controller architecture predicated on airborne data link clusters is thus proposed.Within this architectural framework,the controller deployment issue is reframed as a two-fold problem:subdomain partition-ing and central interaction node selection.We advocate a subdomain segmentation approach grounded in node value ranking(NDVR)and a central interaction node selection methodology predicated on an enhanced Artificial Fish Swarm Algorithm(AFSA).The advanced NDVR-AFSA(Node value ranking-Improved artificial fish swarm algorithm)algorithm makes use of a chaos algorithm for population initialization,boosting population diversity and circumventing premature algorithm convergence.By the integration of adaptive strategies and incorporation of the genetic algorithm’s crossover and mutation operations,the algorithm’s search range adaptability is enhanced,thereby increasing the possibility of obtaining globally optimal solutions,while concurrently augmenting cluster reliability.The simulation results verify the advantages of the NDVR-IAFSA algorithm,achieve a better load balancing effect,improve the reliability of aviation data link cluster,and significantly reduce the average propagation delay and disconnection rate,respectively,by 12.8%and 11.7%.This shows that the optimization scheme has important significance in practical application,and can meet the high requirements of modern sea,land,and air operations to aviation airborne communication networks.

The Impact of Delay in Software-Defined Integrated Terrestrial-Satellite Networks

Satellite communication networks have been evolving from standalone networks with ad-hoc infrastructures to possibly interconnected portions of a wider Future Internet architecture. Experts belonging to the fifth-generation(5 G) standardization committees are considering satellites as a technology to integrate in the 5 G environment. Software Defined Networking(SDN) is one of the paradigms of the next generation of mobile and fixed communications. It can be employed to perform different control functionalities, such as routing, because it allows traffic flow identification based on different parameters and traffic flow management in a centralized way. A centralized set of controllers makes the decisions and sends the corresponding forwarding rules for each traffic flow to the involved intermediate nodes that practically forward data up to the destination. The time to perform this process in integrated terrestrial-satellite networks could be not negligible due to satellite link delays. The aim of this paper is to introduce an SDN-based terrestrial satellite network architecture and to estimate the mean time to deliver the data of a new traffic flow from the source to the destination including the time required to transfer SDN control actions. The practical effect is to identify the maximum performance than can be expected.

Cryopreservation of cynomolgus monkey (Macacafascicularis)spermatozoa in a chemically defined extender

Aim:To establish a method for cynomolgus monkey sperm cryopreservation in a chemically defined extender. Methods:Semen samples were collected by electro-ejaculation from four sexually mature male cynomolgus monkeys. The spermatozoa were frozen in straws by liquid nitrogen vapor using egg-yolk-free Tes-Tris (mTTE) synthetic extender and glycerol as cryoprotectant.The effects of glycerol concentration (1%,3 %,5 %,10 % and 15 % [v/v]) and its equilibration time (10 min,30 min,60 min and 90 min) on post-thaw spermatozoa were examined by sperm motility and sperm head membrane integrity.Results:The post-thaw motility and head membrane integrity of spermatozoa were significantly higher (P<0.05) for 5 % glycerol (42.95±2.55 and 50.39±2.42,respectively) than those of the other groups (1%:19.19±3.22 and 24.84±3.64;3 %:34.23±3.43 and 41.37±3.42;10 %: 15.68±2.36 and 21.39±3.14;15 %:7.47±1.44 and 12.90±2.18).The parameters for 30 min equilibration (42.95±2.55 and 50.39±2.42) were better (P<0.05) than those of the other groups (10 min:31.33±3.06 and 38. 98±3.31;60 min:32.49±3.86 and 40.01±4.18;90 min:31.16±3.66 and 38.30±3.78).Five percent glycerol and 30 min equilibration yielded the highest post-thaw sperm motility and head membrane integrity.Conclusion: Cynomolgus monkey spermatozoa can be successfully cryopreserved in a chemically defined extender,which is related to the concentration and the equilibration time of glycerol.

A Novel Load Balancing Strategy of Software-Defined Cloud/Fog Networking in the Internet of Vehicles

The Internet of Vehicles(IoV)has been widely researched in recent years,and cloud computing has been one of the key technologies in the IoV.Although cloud computing provides high performance compute,storage and networking services,the IoV still suffers with high processing latency,less mobility support and location awareness.In this paper,we integrate fog computing and software defined networking(SDN) to address those problems.Fog computing extends computing and storing to the edge of the network,which could decrease latency remarkably in addition to enable mobility support and location awareness.Meanwhile,SDN provides flexible centralized control and global knowledge to the network.In order to apply the software defined cloud/fog networking(SDCFN) architecture in the IoV effectively,we propose a novel SDN-based modified constrained optimization particle swarm optimization(MPSO-CO) algorithm which uses the reverse of the flight of mutation particles and linear decrease inertia weight to enhance the performance of constrained optimization particle swarm optimization(PSO-CO).The simulation results indicate that the SDN-based MPSO-CO algorithm could effectively decrease the latency and improve the quality of service(QoS) in the SDCFN architecture.

A Dormant Multi-Controller Model for Software Defined Networking

In order to improve the scalability and reliability of Software Defined Networking(SDN),many studies use multiple controllers to constitute logically centralized control plane to provide load balancing and fail over.In this paper,we develop a flexible dormant multi-controller model based on the centralized multi-controller architecture.The dormant multi-controller model allows part of controllers to enter the dormant state under light traffic condition for saving system cost.Meanwhile,through queueing analysis,various performance measures of the system can be obtained.Moreover,we analyze the real traffic of China Education Network and use the results as the parameters of computer simulation and verify the effects of parameters on the system characteristics.Finally,a total expected cost function is established,and genetic algorithm is employed to find the optimal values of various parameters to minimize system cost for the deployment decision making.

Blockchain-Based Secure Distributed Control for Software Defined Optical Networking

Software defined optical networking(SDON)is a critical technology for the next generation network with the advantages of programmable control and etc.As one of the key issues of SDON,the security of control plane has also received extensive attention,especially in certain network scenarios with high security requirement.Due to the existence of vulnerabilities and heavy overhead,the existing firewalls and distributed control technologies cannot solve the control plane security problem well.In this paper,we propose a distributed control architecture for SDON using the blockchain technique(BlockCtrl).The proposed BlockCtrl model introduces the advantages of blockchain into SDON to achieve a high-efficiency fault tolerant control.We have evaluated the performance of our proposed architecture and compared it to the existing models with respect to various metrics including processing rate,recovery latency and etc.The numerical results show that the BlockCtrl is capable of attacks detection and fault tolerant control in SDON with high performance on resource utilization and service correlation.

A Methodology for Reliability of WSN Based on Software Defined Network in Adaptive Industrial Environment

As communication technology and smart manufacturing have developed, the industrial internet of things(IIo T)has gained considerable attention from academia and industry.Wireless sensor networks(WSNs) have many advantages with broad applications in many areas including environmental monitoring, which makes it a very important part of IIo T. However,energy depletion and hardware malfunctions can lead to node failures in WSNs. The industrial environment can also impact the wireless channel transmission, leading to network reliability problems, even with tightly coupled control and data planes in traditional networks, which obviously also enhances network management cost and complexity. In this paper, we introduce a new software defined network(SDN), and modify this network to propose a framework called the improved software defined wireless sensor network(improved SD-WSN). This proposed framework can address the following issues. 1) For a large scale heterogeneous network, it solves the problem of network management and smooth merging of a WSN into IIo T. 2) The network coverage problem is solved which improves the network reliability. 3) The framework addresses node failure due to various problems, particularly related to energy consumption.Therefore, it is necessary to improve the reliability of wireless sensor networks, by developing certain schemes to reduce energy consumption and the delay time of network nodes under IIo T conditions. Experiments have shown that the improved approach significantly reduces the energy consumption of nodes and the delay time, thus improving the reliability of WSN.

Recent advances in chemically defined and tunable hydrogel platforms for organoid culture

Recent developments in organoid culture technologies have made it possible to closely recapitulate intrinsic characteristics of different tissues under in vitro conditions.These organoids act as a translational bridge between the traditional 2D/3D cultures and the in vivo models for studying the tissue development processes,disease modeling,and drug screening.Matrigel and tissue-specific extracellular matrix have been shown to support organoid development,efficiently;however,their chemically undefined nature,non-tunable properties,and associated batch-to-batch variations often limit reproducibility of the assembly process.In this regard,chemically defined platforms offer wider opportunities to optimize and recreate tissue-specific microenvironment.The present review delineates the current research trends in this sphere,focusing on material perspective and the target tissues(e.g.,neural,liver,pancreatic,renal,and intestinal).The review winds up with a discussion on the current limitations and future perspective to provide a basis for future research.

Optimal investment for the defined-contribution pension with stochastic salary under a CEV model

In this paper, we study the optimal investment strategy of defined-contribution pension with the stochastic salary. The investor is allowed to invest in a risk-free asset and a risky asset whose price process follows a constant elasticity of variance model. The stochastic salary follows a stochastic differential equation, whose instantaneous volatility changes with the risky asset price all the time. The HJB equation associated with the optimal investment problem is established, and the explicit solution of the corresponding optimization problem for the CARA utility function is obtained by applying power transform and variable change technique. Finally, we present a numerical analysis.

Autonomic QoS Management Mechanism in Software Defined Network

With the increase of network complexity,the flexibility of network control and management becomes a nontrivial problem.Both Software Defined Network(SDN) and Autonomic Network technologies are sophisticated technologies for the network control and management.These two technologies could be combined together to construct a software defined self-managing solution for the future network.An autonomic QoS management mechanism in Software Defined Network(AQSDN) is proposed in this paper.In AQSDN,the various QoS features can be configured autonomically in an OpenFlow switch through extending the OpenFlow and OF-Config protocols.Based on AQSDN,a novel packet context-aware QoS model(PCaQoS) is also introduced for improving the network QoS.PCaQoS takes packet context into account when packet is marked and managed into forwarding queues.The implementation of a video application's prototype which evaluates the self-configuration feature of the AQSDN and the enhancement ability of the PCaQoS is presented in order to validate this design.

EXPONENTIALLY BOUNDED C-SEMIGROUP AND INTEGRATED SEMIGROUP WITH NONDENSELY DEFINED GENERATORS I: APPROXIMATION:

In this paper, by Laplace transform version of the Trotter-Kato approximation theorem and the integrated C-semigroup introduced by Myadera, the authors obtained some Trotter-Kato approximation theorems on exponentially bounded C-semigroups, where the range of C (and so the domain of the generator) may not be dense. The authors deduced the corresponding results on exponentially bounded integrated semigroups with nondensely generators. The results of this paper extended and perfected the results given by Lizama, Park and Zheng.

Service Function Chain in Small Satellite-Based Software Defined Satellite Networks

Software Defined Satellite Networks(SDSN) are proposed to solve the problems in traditional satellite networks, such as time-consuming configuration and inflexible traffic scheduling. The emerging application of small satellite and research of SDSN make it possible for satellite networks to provide flexible network services. Service Function Chain(SFC) can satisfy this need. In this paper, we are motivated to investigate applying SFC in the small satellite-based SDSN for service delivery. We introduce the structure of the multi-layer constellation-based SDSN. Then, we describe two deployment patterns of SFC in SDSN, the Multi-Domain(MD) pattern and the Satellite Formation(SF) pattern. We propose two algorithms, SFP-MD, and SFP-SF, to calculate the Service Function Path(SFP). We implement the algorithms and conduct contrast experiments in our prototype. Finally, we summarize the applicable conditions of two deployment patterns according to the experimental results in terms of hops, delay, and packet loss rate.

Design of BPS digital frontend for software defined radio receiver

In radio receivers,complete implementation of the software defined radio(SDR) concept is mainly limited by frontend.Based on bandpass sampling(BPS) theory,a flexible digital frontend(DFE) platform for SDR receiver is designed.In order to increase the processing speed,Gigabit Ethernet was applied in the platform at speed of 5×10~8 bit/s.By appropriate design of interpolant according to the position of input RF signals,multi-band receiving can be realized in the platform with suppression more than 35 d B without changing hardware.

Domain-Oriented Software Defined Computing Architecture

With the introduction of software defined hardware by DARPA Electronics Resurgence Initiative,software definition will be the basic attribute of information system.Benefiting from boundary certainty and algorithm aggregation of domain applications,domain-oriented computing architecture has become the technical direction that considers the high flexibility and efficiency of information system.Aiming at the characteristics of data-intensive computing in different scenarios such as Internet of Things(IoT),big data,artificial intelligence(AI),this paper presents a domain-oriented software defined computing architecture,discusses the hierarchical interconnection structure,hybrid granularity computing element and its computational kernel extraction method,finally proves the flexibility and high efficiency of this architecture by experimental comparison.

Analysis of Cardiovascular Risk Factors in Newly Defined Stage 1 Hypertension among Chinese on the Basis of the 2017 ACC/AHA Hypertension Guidelines

In 2017,American College of Cardiology(ACC)/American Heart Association(AHA)et al.jointly released the latest guidelines for adult hypertension,exactly including prevention,diagnosis,assess and treatment,in which blood pressure levels greater than 130/80 mm Hg were defined as hypertension[1].Based on these modified guidelines,the morbidity of hypertension in US increased from 32%to 46%.

Naive Echo-State-Network Based Services Awareness Algorithm of Software Defined Optical Networks

As internet services newly emerge with diversity and complexity, great challenges and demands are presented to the Open Flow controlled software defined optical networks(SDON) to achieve better match between services and SDON. With this aim, this paper proposes a naive Echo-State-Network(Naive-ESN) based services awareness algorithm of the software defined optical network, where the naive ESN model adopts the ring topology structure and generates the probability output result to determine the Qo S policy of SDON. Moreover, the Naive-ESN engine is also designed in controller node of SDON to perform services awareness by obtaining service traffic features from data plan, together with some necessary extension of the Open Flow protocol. Test results show that the proposed approach is able to improved services-oriented supporting ability of SDON.

Software Defined Optical Networks and Its Innovation Environment

Software defined optical networks （SDONs） integrate software defined technology with optical communication networks and represent the promising development trend of future optical networks. The key technologies for SDONs include software-defined optical transmission, switching, and networking. The main features include control and transport separation, hard-ware universalization, protocol standardization, controllable optical network, and flexible optical network applications. This paper introduces software defined optical networks and its innovation environment, in terms of network architecture, protocol extension solution, experiment platform and typical applications. Batch testing has been conducted to evaluate the performance of this SDON testbed. The results show that the SDON testbed has good scalability in different sizes. Meanwhile, we notice that controller output bandwidth has great influence on lightpath setup delay.