A frequency domain modeling method is given for a soft switching combination DC DC converter worked in current controlled discrete pulse modulation mode. A equivalent model for the current loop as one forward com...A frequency domain modeling method is given for a soft switching combination DC DC converter worked in current controlled discrete pulse modulation mode. A equivalent model for the current loop as one forward component in the converter system is built up directly at the first time. Using time domain simulation and Fourier transform, the method is helpful for system performance analysis and converter voltage regulator design, and can be applied to soft switching combination inverter.展开更多
BACKGROUND Tyrosine kinase inhibitors(TKI)have been the standard first-line therapy for advanced non-small cell lung cancer(NSCLC)of epidermal growth factor receptor(EGFR)sensitive mutations.Uncommon EGFR mutations ar...BACKGROUND Tyrosine kinase inhibitors(TKI)have been the standard first-line therapy for advanced non-small cell lung cancer(NSCLC)of epidermal growth factor receptor(EGFR)sensitive mutations.Uncommon EGFR mutations are increasingly reported with the development of next-generation sequencing.However,their sensitivity to TKIs is variable with limited clinical evidence.CASE SUMMARY Here,we report a patient with the rare delE709_T710insD mutation,who showed the favorable efficacy of dacomitinib and achieved a partial response with a progression-free survival of 7.0 mo.CONCLUSION To our knowledge,this is the first report displaying the clinical efficacy of dacomitinib for patients with delE709_T710insD,which may help to provide alternatives in non-classical variant NSCLC patients.Further studies are warranted to make the optimal choice of EGFR-TKI for rare mutations.展开更多
At the invitation of CAFIU,an 8-member delegation of the Kazankai Foundation of Japan headed by Executive Director Hoshi Hiroto visited China from June 29 to July 3,2015.In Beijing,CAFIU Vice-President Ai Ping met wit...At the invitation of CAFIU,an 8-member delegation of the Kazankai Foundation of Japan headed by Executive Director Hoshi Hiroto visited China from June 29 to July 3,2015.In Beijing,CAFIU Vice-President Ai Ping met with thedelegation.Ai Ping stressed that China-Japan people-to-people exchanges should play a positive role in improving the bilateral relations展开更多
At the invitation of the China-Japan Friendship Association(CJFA),a 75-member Japanese delegation composed of students from four senior middle schools in Chiba and Ibaragi Prefectures paid a visit to Sichuan from Nove...At the invitation of the China-Japan Friendship Association(CJFA),a 75-member Japanese delegation composed of students from four senior middle schools in Chiba and Ibaragi Prefectures paid a visit to Sichuan from November 24 to 26,2006.展开更多
In the afternoon of September 11,Governor of Hebei Province Zhang Qingwei met with the delegation led by Chinalco Chairman Ge Honglin and General Manager of Shenhua Group Ling Wen in Shijiazhuang,and attended the coop...In the afternoon of September 11,Governor of Hebei Province Zhang Qingwei met with the delegation led by Chinalco Chairman Ge Honglin and General Manager of Shenhua Group Ling Wen in Shijiazhuang,and attended the cooperation agreement signing ceremony for aluminum oxide project between展开更多
At the invitation of the China-Malaysia Friendship Association, a 96-member Chi- nese youth dance delegation organized by the CPAFFC and the Chinese Dancers Association, went to Pinang, a famous
文摘A frequency domain modeling method is given for a soft switching combination DC DC converter worked in current controlled discrete pulse modulation mode. A equivalent model for the current loop as one forward component in the converter system is built up directly at the first time. Using time domain simulation and Fourier transform, the method is helpful for system performance analysis and converter voltage regulator design, and can be applied to soft switching combination inverter.
文摘BACKGROUND Tyrosine kinase inhibitors(TKI)have been the standard first-line therapy for advanced non-small cell lung cancer(NSCLC)of epidermal growth factor receptor(EGFR)sensitive mutations.Uncommon EGFR mutations are increasingly reported with the development of next-generation sequencing.However,their sensitivity to TKIs is variable with limited clinical evidence.CASE SUMMARY Here,we report a patient with the rare delE709_T710insD mutation,who showed the favorable efficacy of dacomitinib and achieved a partial response with a progression-free survival of 7.0 mo.CONCLUSION To our knowledge,this is the first report displaying the clinical efficacy of dacomitinib for patients with delE709_T710insD,which may help to provide alternatives in non-classical variant NSCLC patients.Further studies are warranted to make the optimal choice of EGFR-TKI for rare mutations.
文摘At the invitation of CAFIU,an 8-member delegation of the Kazankai Foundation of Japan headed by Executive Director Hoshi Hiroto visited China from June 29 to July 3,2015.In Beijing,CAFIU Vice-President Ai Ping met with thedelegation.Ai Ping stressed that China-Japan people-to-people exchanges should play a positive role in improving the bilateral relations
文摘At the invitation of the China-Japan Friendship Association(CJFA),a 75-member Japanese delegation composed of students from four senior middle schools in Chiba and Ibaragi Prefectures paid a visit to Sichuan from November 24 to 26,2006.
文摘In the afternoon of September 11,Governor of Hebei Province Zhang Qingwei met with the delegation led by Chinalco Chairman Ge Honglin and General Manager of Shenhua Group Ling Wen in Shijiazhuang,and attended the cooperation agreement signing ceremony for aluminum oxide project between
文摘At the invitation of the China-Malaysia Friendship Association, a 96-member Chi- nese youth dance delegation organized by the CPAFFC and the Chinese Dancers Association, went to Pinang, a famous
