BACKGROUND Locally advanced gastric cancer(LAGC)is a common malignant tumor.In recent years,neoadjuvant chemotherapy has gradually become popular for the treatment of LAGC.AIM To investigate the efficacy of oxaliplati...BACKGROUND Locally advanced gastric cancer(LAGC)is a common malignant tumor.In recent years,neoadjuvant chemotherapy has gradually become popular for the treatment of LAGC.AIM To investigate the efficacy of oxaliplatin combined with a tigio neoadjuvant chemotherapy regimen vs a conventional chemotherapy regimen for LAGC.METHODS Ninety patients with LAGC were selected and randomly divided into control and study groups with 45 patients in each group,according to the numerical table method.The control group was treated with conventional chemotherapy,and the study group was treated with oxaliplatin combined with tigio-neoadjuvant che-motherapy.The primary outcome measures were the clinical objective response rate(ORR)and surgical resection rate(SRR),whereas the secondary outcome measures were safety and Karnofsky Performance Status score.RESULTS The ORR in the study group was 80.00%,which was significantly higher than that of the control group(57.78%).In the study group,SRR was 75.56%,which was significantly higher than that of the control group(57.78%).There were 15.56%adverse reactions in the study group and 35.56%in the control group.These differences were statistically significant between the two groups.CONCLUSION The combination of oxaliplatin and tigio before surgery as neoadjuvant chemotherapy for patients with LAGC can effectively improve the ORR and SRR and is safe.展开更多
A detailed examination on various aspects of the southwest monsoon over the Indian subcontinent using analyses and forecasts of the NCMRWF global data assimilation and forecast system for the years 1994 and 1996 is c...A detailed examination on various aspects of the southwest monsoon over the Indian subcontinent using analyses and forecasts of the NCMRWF global data assimilation and forecast system for the years 1994 and 1996 is carried out in this study. Objective procedures developed by Ramesh et al. (1996) based on the monsoon 1995 data are employed in the present work. It is found that all the deterministic features of the summer monsoon viz., the onset, its advancement, stagnation/revival and the withdrawal, can reasonably by prognosticated after employing the objective methodologies and monitoring daily variations of certain derived quantities from the large scale analyses and forecasts. Further, a good correspondence of the observed large scale/synoptic scale circulation features and the observed rainfall etc. with the deterministic characteristics of the summer monsoon show a good prospect for real time prognosis of the important summer monsoon activities over the Indian subcontinent.展开更多
The goods delivery process of one cold rolling plant was analyzed and the result shows it is necessary to reengineer and optimize this process. The goods delivery forecasting system was proposed after choosing suitabl...The goods delivery process of one cold rolling plant was analyzed and the result shows it is necessary to reengineer and optimize this process. The goods delivery forecasting system was proposed after choosing suitable sampling methods. It is necessary to verify the efficiency of this optimization before the real system adjustment, which is costly and dangerous to some distance. A Simulation method, which employs object oriented paradigm to construct simulation system and stochastic approach to calculate process parameters, was put forward. The simulation result shows the feasibility of this method.展开更多
The 19th National Congress of the Communist Party of China（CPC）has concluded in Beijing and the new CPC leadership was elected.What are the core objectives that the Party with its new leadership after this congress ...The 19th National Congress of the Communist Party of China（CPC）has concluded in Beijing and the new CPC leadership was elected.What are the core objectives that the Party with its new leadership after this congress now focused on,and what sort of management will they need？展开更多
文摘BACKGROUND Locally advanced gastric cancer(LAGC)is a common malignant tumor.In recent years,neoadjuvant chemotherapy has gradually become popular for the treatment of LAGC.AIM To investigate the efficacy of oxaliplatin combined with a tigio neoadjuvant chemotherapy regimen vs a conventional chemotherapy regimen for LAGC.METHODS Ninety patients with LAGC were selected and randomly divided into control and study groups with 45 patients in each group,according to the numerical table method.The control group was treated with conventional chemotherapy,and the study group was treated with oxaliplatin combined with tigio-neoadjuvant che-motherapy.The primary outcome measures were the clinical objective response rate(ORR)and surgical resection rate(SRR),whereas the secondary outcome measures were safety and Karnofsky Performance Status score.RESULTS The ORR in the study group was 80.00%,which was significantly higher than that of the control group(57.78%).In the study group,SRR was 75.56%,which was significantly higher than that of the control group(57.78%).There were 15.56%adverse reactions in the study group and 35.56%in the control group.These differences were statistically significant between the two groups.CONCLUSION The combination of oxaliplatin and tigio before surgery as neoadjuvant chemotherapy for patients with LAGC can effectively improve the ORR and SRR and is safe.
文摘A detailed examination on various aspects of the southwest monsoon over the Indian subcontinent using analyses and forecasts of the NCMRWF global data assimilation and forecast system for the years 1994 and 1996 is carried out in this study. Objective procedures developed by Ramesh et al. (1996) based on the monsoon 1995 data are employed in the present work. It is found that all the deterministic features of the summer monsoon viz., the onset, its advancement, stagnation/revival and the withdrawal, can reasonably by prognosticated after employing the objective methodologies and monitoring daily variations of certain derived quantities from the large scale analyses and forecasts. Further, a good correspondence of the observed large scale/synoptic scale circulation features and the observed rainfall etc. with the deterministic characteristics of the summer monsoon show a good prospect for real time prognosis of the important summer monsoon activities over the Indian subcontinent.
文摘The goods delivery process of one cold rolling plant was analyzed and the result shows it is necessary to reengineer and optimize this process. The goods delivery forecasting system was proposed after choosing suitable sampling methods. It is necessary to verify the efficiency of this optimization before the real system adjustment, which is costly and dangerous to some distance. A Simulation method, which employs object oriented paradigm to construct simulation system and stochastic approach to calculate process parameters, was put forward. The simulation result shows the feasibility of this method.
文摘The 19th National Congress of the Communist Party of China（CPC）has concluded in Beijing and the new CPC leadership was elected.What are the core objectives that the Party with its new leadership after this congress now focused on,and what sort of management will they need？
