Adolescent idiopathic scoliosis (AIS) is one of the most prevalent diseases among teenagers, with an incidence rate of 1-3% worldwide, and at least 0.02% of patients require surgical treatment. The "gold standard"...Adolescent idiopathic scoliosis (AIS) is one of the most prevalent diseases among teenagers, with an incidence rate of 1-3% worldwide, and at least 0.02% of patients require surgical treatment. The "gold standard" procedure is instrumentation and fusion of 10 or more vertebrae with forceful correction of the deformity.Although autogenous bone grafts are the "gold standard" for spine fusion, significant progress has been made in discovering bone graft alternatives, including freeze-dried allograft, demineralized bone matrix (DBM), triosite ceramics, and bone marrow aspirate (BMA), which have been used as substitutes for iliac crest in AIS surgery.展开更多
基金grants from the National Natural Science Foundation of China,Shanghai Natural Science Foundation,Youth Project of Shanghai Municipal Health and Family Planning Commission
文摘Adolescent idiopathic scoliosis (AIS) is one of the most prevalent diseases among teenagers, with an incidence rate of 1-3% worldwide, and at least 0.02% of patients require surgical treatment. The "gold standard" procedure is instrumentation and fusion of 10 or more vertebrae with forceful correction of the deformity.Although autogenous bone grafts are the "gold standard" for spine fusion, significant progress has been made in discovering bone graft alternatives, including freeze-dried allograft, demineralized bone matrix (DBM), triosite ceramics, and bone marrow aspirate (BMA), which have been used as substitutes for iliac crest in AIS surgery.