Objective:This study aimed to explore the effects of different types of palatal lateral excisions on the growth and development of the maxilla and dental arch, and to investigate the underlying mechanisms. Methods: A ...Objective:This study aimed to explore the effects of different types of palatal lateral excisions on the growth and development of the maxilla and dental arch, and to investigate the underlying mechanisms. Methods: A total of 112 3-week-old Sprague-Dawley (SD) male rats were randomly divided into a control and 3 experimental groups: the mucoperiosteal denudation group, the mucosal flap excision group, and the periosteum excision group. In the experimental groups, bilateral mucoperiosteal, mucosal flap and periosteum were excised respectively in the lateral one half of the palate. Four rats in each group were randomly chosen for sacrifice every two weeks. The maxilla was dissected following the excision. The widths of the maxilla and dental arch were measured and the histological phenomena were investigated at different phases. At the same time, 12 animals in each group were sequentially injected with calcein every two weeks. Three animals in each group, whose fluorescent labeling was used, were sacrificed for investigating bone formation at Week 8 following injection. Results: (1) Each experimental group presented the constriction of the maxilla and dental arch. The upper first molars in the experimental groups inclined medially. The mucoperio-steal denudation group showed the largest degree of effect followed by the periosteum excision group. The indices of the mucosal flap excision group, which retained the structures of the periosteum layer, had the most approximate values to the control group; (2) Different histological changes among the experimental groups were detected. The fibers penetrated into the palatal bone as Sharpey's fibers in the mucoperiosteal denudation group. The pattern of bone deposition was the bundle type. Sharpey's fibers were not found in the mucosal flap and periosteum excision groups and the depositions of palatal bone were the lamellar type as those in the control group; (3) The rates of bone deposition in the experimental groups decreased compared with the control group. The rates in different phases were the most approximate values to those of the control group in the mucosal flap excision group, which has the same structure of periosteum as the control group. Conclusion: There were different effects on the growth and development of the maxilla and dental arch in different types of palatal lateral excisions. Periosteum is important for bone for-mation and deposition pattern. The prevention of Sharpey's fibers forming and attaching to the palatine can effectively avert the following malformation.展开更多
背景:目前对于骨性Ⅲ类错(牙合)的诊断和治疗都具有一定的挑战性,主要是因为这类错(牙合)类型的患者颅面部结构生长的多样性和不可预测性,治疗决策及其成败在很大程度上取决于骨性Ⅲ类错(牙合)患者未来的生长潜力。目的:综述儿童骨性Ⅲ...背景:目前对于骨性Ⅲ类错(牙合)的诊断和治疗都具有一定的挑战性,主要是因为这类错(牙合)类型的患者颅面部结构生长的多样性和不可预测性,治疗决策及其成败在很大程度上取决于骨性Ⅲ类错(牙合)患者未来的生长潜力。目的:综述儿童骨性Ⅲ类错(牙合)牙弓和基骨弓生长发育的研究现状研究进展。方法:在PubMed、中国知网、万方、Medline数据库中进行相关文献检索,以“malocclusion,skeletal class Ⅲ malocclusion,dental arch,basal arch,growth and development,mixed dentition,tongue,etiology,jaw”为英文检索词进行检索,以“错(牙合)、骨性Ⅲ类错(牙合)、牙弓、基骨弓、生长发育、替牙期、舌、病因、颌骨”为中文检索词进行检索,最后纳入64篇文献进行仔细阅读分析与总结。结果与结论:①骨性Ⅲ类错(牙合)畸形是儿童(牙合)发育异常中较为常见的一种错(牙合)类型,其颌骨、牙弓、基骨弓在一定程度上也会受到遗传和环境因素的影响。②颌骨、牙弓、基骨弓作为特殊的颅颌面复合体有相同的增长变化趋势,具有协同性。③骨性Ⅲ类错(牙合)患儿的上、下颌骨生长速率与年龄和骨龄相关,颌骨长度的增长在不同生长高峰期的速率也有差异,一直持续到患儿成年。④正确预测生长发育高峰期,抑制骨性Ⅲ类儿童下颌骨的生长发育就显得尤为重要。⑤由于骨性Ⅲ类错(牙合)畸形的治疗具有复杂性,因此及时发现上、下颌骨、牙齿、牙列及咬合关系等异常发育的情况,正确诊断,早期矫治,适时干预对于引导儿童颅颌面的正常生长发育具有重要意义。⑥目前对于儿童牙弓、基骨弓生长发育的研究主要集中在正常(牙合),因为骨性Ⅲ类错(牙合)畸形患儿一旦开始治疗,就不能继续观察其生长发育特点,因此未来还需对骨性Ⅲ类错(牙合)畸形的生长发育机制进行进一步研究。展开更多
目的探讨13—18岁汉族正常骀青少年上牙弓后段可利用间隙的增龄性变化。方法对26名汉族正常骀青少年(男12人,女14人)13—18岁每年同期拍摄头颅侧位定位片,连续6年,进行 X 线头影测量纵向分析。结果(1)13—18岁上牙弓后段可用间隙的变化...目的探讨13—18岁汉族正常骀青少年上牙弓后段可利用间隙的增龄性变化。方法对26名汉族正常骀青少年(男12人,女14人)13—18岁每年同期拍摄头颅侧位定位片,连续6年,进行 X 线头影测量纵向分析。结果(1)13—18岁上牙弓后段可用间隙的变化存在明显的性别差异,女性每侧间隙共增长3.29mm,男性共增长5.25mm;(2)13—18岁牙弓后段可利用间隙的增加与上颌骨的生长改建及上颌磨牙近中漂移有关;(3)女性比男性较早结束颌骨的生长改建,女性14岁、男性15岁上颌后段骨改建基本结束;13—18岁期间存在上颌磨牙近中漂移现象,第二、三磨牙的萌出力可能会加速其近中漂移。结论上牙弓可用间隙的增龄性变化具有年龄、性别等差异,临床上可参考本研究结果预测相关可用间隙。展开更多
文摘Objective:This study aimed to explore the effects of different types of palatal lateral excisions on the growth and development of the maxilla and dental arch, and to investigate the underlying mechanisms. Methods: A total of 112 3-week-old Sprague-Dawley (SD) male rats were randomly divided into a control and 3 experimental groups: the mucoperiosteal denudation group, the mucosal flap excision group, and the periosteum excision group. In the experimental groups, bilateral mucoperiosteal, mucosal flap and periosteum were excised respectively in the lateral one half of the palate. Four rats in each group were randomly chosen for sacrifice every two weeks. The maxilla was dissected following the excision. The widths of the maxilla and dental arch were measured and the histological phenomena were investigated at different phases. At the same time, 12 animals in each group were sequentially injected with calcein every two weeks. Three animals in each group, whose fluorescent labeling was used, were sacrificed for investigating bone formation at Week 8 following injection. Results: (1) Each experimental group presented the constriction of the maxilla and dental arch. The upper first molars in the experimental groups inclined medially. The mucoperio-steal denudation group showed the largest degree of effect followed by the periosteum excision group. The indices of the mucosal flap excision group, which retained the structures of the periosteum layer, had the most approximate values to the control group; (2) Different histological changes among the experimental groups were detected. The fibers penetrated into the palatal bone as Sharpey's fibers in the mucoperiosteal denudation group. The pattern of bone deposition was the bundle type. Sharpey's fibers were not found in the mucosal flap and periosteum excision groups and the depositions of palatal bone were the lamellar type as those in the control group; (3) The rates of bone deposition in the experimental groups decreased compared with the control group. The rates in different phases were the most approximate values to those of the control group in the mucosal flap excision group, which has the same structure of periosteum as the control group. Conclusion: There were different effects on the growth and development of the maxilla and dental arch in different types of palatal lateral excisions. Periosteum is important for bone for-mation and deposition pattern. The prevention of Sharpey's fibers forming and attaching to the palatine can effectively avert the following malformation.
文摘背景:目前对于骨性Ⅲ类错(牙合)的诊断和治疗都具有一定的挑战性,主要是因为这类错(牙合)类型的患者颅面部结构生长的多样性和不可预测性,治疗决策及其成败在很大程度上取决于骨性Ⅲ类错(牙合)患者未来的生长潜力。目的:综述儿童骨性Ⅲ类错(牙合)牙弓和基骨弓生长发育的研究现状研究进展。方法:在PubMed、中国知网、万方、Medline数据库中进行相关文献检索,以“malocclusion,skeletal class Ⅲ malocclusion,dental arch,basal arch,growth and development,mixed dentition,tongue,etiology,jaw”为英文检索词进行检索,以“错(牙合)、骨性Ⅲ类错(牙合)、牙弓、基骨弓、生长发育、替牙期、舌、病因、颌骨”为中文检索词进行检索,最后纳入64篇文献进行仔细阅读分析与总结。结果与结论:①骨性Ⅲ类错(牙合)畸形是儿童(牙合)发育异常中较为常见的一种错(牙合)类型,其颌骨、牙弓、基骨弓在一定程度上也会受到遗传和环境因素的影响。②颌骨、牙弓、基骨弓作为特殊的颅颌面复合体有相同的增长变化趋势,具有协同性。③骨性Ⅲ类错(牙合)患儿的上、下颌骨生长速率与年龄和骨龄相关,颌骨长度的增长在不同生长高峰期的速率也有差异,一直持续到患儿成年。④正确预测生长发育高峰期,抑制骨性Ⅲ类儿童下颌骨的生长发育就显得尤为重要。⑤由于骨性Ⅲ类错(牙合)畸形的治疗具有复杂性,因此及时发现上、下颌骨、牙齿、牙列及咬合关系等异常发育的情况,正确诊断,早期矫治,适时干预对于引导儿童颅颌面的正常生长发育具有重要意义。⑥目前对于儿童牙弓、基骨弓生长发育的研究主要集中在正常(牙合),因为骨性Ⅲ类错(牙合)畸形患儿一旦开始治疗,就不能继续观察其生长发育特点,因此未来还需对骨性Ⅲ类错(牙合)畸形的生长发育机制进行进一步研究。
文摘目的探讨13—18岁汉族正常骀青少年上牙弓后段可利用间隙的增龄性变化。方法对26名汉族正常骀青少年(男12人,女14人)13—18岁每年同期拍摄头颅侧位定位片,连续6年,进行 X 线头影测量纵向分析。结果(1)13—18岁上牙弓后段可用间隙的变化存在明显的性别差异,女性每侧间隙共增长3.29mm,男性共增长5.25mm;(2)13—18岁牙弓后段可利用间隙的增加与上颌骨的生长改建及上颌磨牙近中漂移有关;(3)女性比男性较早结束颌骨的生长改建,女性14岁、男性15岁上颌后段骨改建基本结束;13—18岁期间存在上颌磨牙近中漂移现象,第二、三磨牙的萌出力可能会加速其近中漂移。结论上牙弓可用间隙的增龄性变化具有年龄、性别等差异,临床上可参考本研究结果预测相关可用间隙。
