Alcohol use disorders represent a heterogeneous spectrum of clinical manifestations that have been defined by the Diagnostic and Statistical Manual of Mental Disorders-5. Excessive alcohol intake can lead to damage of...Alcohol use disorders represent a heterogeneous spectrum of clinical manifestations that have been defined by the Diagnostic and Statistical Manual of Mental Disorders-5. Excessive alcohol intake can lead to damage of various organs, including the liver. Alcoholic liver disease includes different injuries ranging from steatosis to cirrhosis and implicates a diagnostic assessment of the liver disease and of its possible complications. There is growing interest in the possible different tools for assessing previous alcohol consumption and for establishing the severity of liver injury, especially by noninvasive methods.展开更多
Based on digital land use data from 1995 to 2000 and road data, the land use and landscape changes of Golmud, Qumaleb and Zhidoi are studied on a macro-scale. Land use and landscape changes in highway buffer zones and...Based on digital land use data from 1995 to 2000 and road data, the land use and landscape changes of Golmud, Qumaleb and Zhidoi are studied on a macro-scale. Land use and landscape changes in highway buffer zones and city expansion are special subjects. A new formula is used to define the exact degree of dynamic land use. To adequately define land use and landscape pattern changes, the buffer zones, illustrating the changes at different distances from the road, are recognized with ArcGIS 8.1 software. Prominent changes took place in land use and landscape patterns from 1995 to 2000, and the area of built-up land increased by 323.8%. The comprehensive degree of dynamic land use is 2.25, and the degree of dynamic land use of built-up land is the highest, followed by cultivated land. Woodland has the lowest value. The used degree index of land resources declined by 38.8 from 1995 to 2000. Landscape changed dramatically which influenced ecological processes immensely. Different from the corridor effect of other traffic routes, the corridor effect of this section of road is not obvious and its “point” radiation effect can be easily seen. The expanding range of Golmud City is confined to a 3 km buffer, while for Wudaoliang, it is 1 km. No land use change happened in the Nanshankou buffer.展开更多
AIM: To investigate if there is a correlation between electrical activity measured by electrogastrography (EGG) and contractile activity of the stomach as measured by antroduodenal manometry (ADM). We also studied whe...AIM: To investigate if there is a correlation between electrical activity measured by electrogastrography (EGG) and contractile activity of the stomach as measured by antroduodenal manometry (ADM). We also studied whether the underlying motility disorder could be predicted from EGG parameters. METHODS: We compared 21 parameters measured from EGG with 8 parameters measured from ADM. The ability of EGG to identify the underlying diagnosis was tested by comparing EGG parameters for each diagnosis group against other patients. The study comprised recordings from 148 patients and 125 females. Their median age was 45 (range 17-76) years. RESULTS: We found few and weak correlations between EGG and ADM. Specifically the correlation between parameters reflecting the response to meal was poor (r = -0.07, P = 0.39). The discriminatory power of EGG for underlying motility disorder was also low. Patients with slow transit constipation (STC) showed a lower postprandial power in normogastric (3.7 ± 0.5 vs 4.0 ± 0.5) and tachygastric (3.5 ± 0.4 vs 3.7 ± 0.4) regions, a lower percentage of time with normogastria [87.2 (56.5-100)% vs 95.7 (0-100)%], and a higher percentage of time with tachygastria [9.3 (0-33)% vs 3.5 (0-100)%] and bradygastria [1.8 (0-20)% vs 0 (0-17.1)%]. Patients with irritable bowel syndrome had a higher percentage of time with normogastria [96.5 (62.5-100)% vs 93.3 (0-100)%] and a less unstable dominant frequency as measured by the instability coefficient [15 (3-77) vs 24 (2-72)]. CONCLUSION: EGG and ADM seem to measure different aspects of gastric motor activity but cannot show a spatial correlation. The diagnostic value of EGG is poor, but EGG may have some value for the identification of patients with STC.展开更多
This paper reports a study of complex focussing acoustic fields of a convex phased array probe widely used in ultrasonic diagnostic B-scanner. The time delay necessary for electronic focussing and for geometric focuss...This paper reports a study of complex focussing acoustic fields of a convex phased array probe widely used in ultrasonic diagnostic B-scanner. The time delay necessary for electronic focussing and for geometric focussing of complex focussing is given. By means of Helmholtz's integral formula, the expressions of acoustic fields were obtained for the electronic focussing and complex focussing.With Simpson's numerical integral, a great deal of computations was carried out with an 86 / 330 computer. By means of using different parameters, an optimum focal range and beam width of a 4 sequences electronic and complex focussing acoustic system was selected. With an EUB-40 ultrasound diagnostic B-scanner produced by the Hitachi company, the lateral focussing acoustic field and lateral resolution in an echoic tank were photographed by latticing method and the experimental result is consistent with the theory.展开更多
Objective To compare the diagnostic efficiency of the thyroid imaging reporting and data system(TIRADS),the Bethesda system for reporting thyroid cytopathology(BSRTC)and BRAFV600Edetection,and their combined use in th...Objective To compare the diagnostic efficiency of the thyroid imaging reporting and data system(TIRADS),the Bethesda system for reporting thyroid cytopathology(BSRTC)and BRAFV600Edetection,and their combined use in the differentiation between benign and malignant thyroid nodules.Methods One hundred展开更多
目的用 Meta 分析方法研究^(18)F-FDG PET 在结直肠癌复发诊断中的价值,并探讨其主要的误诊原因。方法收集2007年2月8日前公开发表的关于 PET 对结直肠癌术后复发评估的所有中英文文献,对纳入文献进行方法学质量评估后,用统计软件计算...目的用 Meta 分析方法研究^(18)F-FDG PET 在结直肠癌复发诊断中的价值,并探讨其主要的误诊原因。方法收集2007年2月8日前公开发表的关于 PET 对结直肠癌术后复发评估的所有中英文文献,对纳入文献进行方法学质量评估后,用统计软件计算综合灵敏度(Se)、特异性(Sp)、诊断优势比(DOR),并绘制综合受试者工作特征(SROC)曲线。结果共有19篇文献纳入。PET评价结直肠癌全身复发及转移的综合 Se 为89.5%[95%可信区间(CI)86.6%～92.0%],综合 Sp为78.3%(95%CI 72.0%～83.8%),综合 DOR 为28.114(95%CI 12.120～65.216);SROC 曲线下面积为0.8857,Q~*值为0.8163。结论 ^(18)F-FDG PET 在结直肠癌术后复发诊断中有较高的价值。展开更多
AIM: To assess if certain triaging rules could be established to optimize the yield of mesenteric angiography. METHODS: Medical records of 101 patients were retrospectively reviewed and parameters relating to age, gen...AIM: To assess if certain triaging rules could be established to optimize the yield of mesenteric angiography. METHODS: Medical records of 101 patients were retrospectively reviewed and parameters relating to age, gender, pulse rate, blood pressure, serum hemoglobin, intensive care unit(ICU) admission, and the number of packed red blood cells(PRBC) transfused in the 12 and 24 h prior to the angiography were tabulated in two groups with positive and negative angiography results. RESULTS: We found no correlation between gender, pulse rate, blood pressure or serum hemoglobin and positivity of the mesenteric angiogram. But patients with positive angiogram were found to be on average 7 years older(73.2 years vs 65.9 years old)(P = 0.02). Angiogram was positive in 39.3 %(11/28) of patientsadmitted in ICU vs 23.2%(17/73) who were admitted elsewhere in the hospital(P = 0.03). In the 12 and 24 h prior to angiography, patients with a positive angiogram received a mean of 2.7 ± 2.3 and 3.3 ± 2.6 units of PRBC s respectively, while patients with a negative angiogram had a mean of 1.6 ± 1.9(P = 0.02) and 2.1 ± 2.6 units(P = 0.04) received respectively in the same period. CONCLUSION: Older age, ICU admission, having received at least 4 units PRBC over 12 h or 5 units over 24 h prior to angiogram are leading indicators for a positive study.展开更多
Objective To investigate the role of dobutamine stree echocardiography in evaluating cardiac betaadrenergic receptor (AR) function and responsive ness in children Methods Left ventricular ejection fraction (EF), fr...Objective To investigate the role of dobutamine stree echocardiography in evaluating cardiac betaadrenergic receptor (AR) function and responsive ness in children Methods Left ventricular ejection fraction (EF), fractional shortening (FS), left ventricular end systolic volume index (ESVI), the ratio of systolic b lood pressure and ESVI (SP/ESVI) were measured by dobutamine stress echocardiogr aphy (DSE) in 30 children with AR hypersensitivity, 15 children with dilated cardiomyopathy and 30 normal children respectively Results Before pharmacological stress, EF and FS were 072 and 039 r es pectively in AR hypersensitivity group versus 070 and 035 respectively i n control group There was no difference of the indices between the two groups ( P >005) SP/ESVI was 076, higher than the value of 066 in co ntro l group ( P <005); EF, FS and SP/ESVI were 041, 015 and 01 0 re spectively, which were significantly lower than those in control group After d o butamine stress of 5?gkg-1min-1 and 10?gkg-1min -1, EF, FS and SP/ESVI were sig nificantly increased in patients with AR hypersensitivity and there were no changes in children with dilated cardiomyopathy compared with values of baseline Conclusion Cardiac AR function and responsiveness can be evaluated by dobutamine stress echocardiography展开更多
文摘Alcohol use disorders represent a heterogeneous spectrum of clinical manifestations that have been defined by the Diagnostic and Statistical Manual of Mental Disorders-5. Excessive alcohol intake can lead to damage of various organs, including the liver. Alcoholic liver disease includes different injuries ranging from steatosis to cirrhosis and implicates a diagnostic assessment of the liver disease and of its possible complications. There is growing interest in the possible different tools for assessing previous alcohol consumption and for establishing the severity of liver injury, especially by noninvasive methods.
基金The National Key Basic Research Special Fund, No.Gl 998040800 The Core Project of Institute of Geographic Sciences and Natural Resources Research of CAS for Knowledge Innovation, No. CXIOG-E01-01,No.CXIOG-A00-03-02.
文摘Based on digital land use data from 1995 to 2000 and road data, the land use and landscape changes of Golmud, Qumaleb and Zhidoi are studied on a macro-scale. Land use and landscape changes in highway buffer zones and city expansion are special subjects. A new formula is used to define the exact degree of dynamic land use. To adequately define land use and landscape pattern changes, the buffer zones, illustrating the changes at different distances from the road, are recognized with ArcGIS 8.1 software. Prominent changes took place in land use and landscape patterns from 1995 to 2000, and the area of built-up land increased by 323.8%. The comprehensive degree of dynamic land use is 2.25, and the degree of dynamic land use of built-up land is the highest, followed by cultivated land. Woodland has the lowest value. The used degree index of land resources declined by 38.8 from 1995 to 2000. Landscape changed dramatically which influenced ecological processes immensely. Different from the corridor effect of other traffic routes, the corridor effect of this section of road is not obvious and its “point” radiation effect can be easily seen. The expanding range of Golmud City is confined to a 3 km buffer, while for Wudaoliang, it is 1 km. No land use change happened in the Nanshankou buffer.
基金Supported by funds from the Swedish Research Council (grant 2002-5489) and the Swedish Society of Medicine (Ihre’s fond)
文摘AIM: To investigate if there is a correlation between electrical activity measured by electrogastrography (EGG) and contractile activity of the stomach as measured by antroduodenal manometry (ADM). We also studied whether the underlying motility disorder could be predicted from EGG parameters. METHODS: We compared 21 parameters measured from EGG with 8 parameters measured from ADM. The ability of EGG to identify the underlying diagnosis was tested by comparing EGG parameters for each diagnosis group against other patients. The study comprised recordings from 148 patients and 125 females. Their median age was 45 (range 17-76) years. RESULTS: We found few and weak correlations between EGG and ADM. Specifically the correlation between parameters reflecting the response to meal was poor (r = -0.07, P = 0.39). The discriminatory power of EGG for underlying motility disorder was also low. Patients with slow transit constipation (STC) showed a lower postprandial power in normogastric (3.7 ± 0.5 vs 4.0 ± 0.5) and tachygastric (3.5 ± 0.4 vs 3.7 ± 0.4) regions, a lower percentage of time with normogastria [87.2 (56.5-100)% vs 95.7 (0-100)%], and a higher percentage of time with tachygastria [9.3 (0-33)% vs 3.5 (0-100)%] and bradygastria [1.8 (0-20)% vs 0 (0-17.1)%]. Patients with irritable bowel syndrome had a higher percentage of time with normogastria [96.5 (62.5-100)% vs 93.3 (0-100)%] and a less unstable dominant frequency as measured by the instability coefficient [15 (3-77) vs 24 (2-72)]. CONCLUSION: EGG and ADM seem to measure different aspects of gastric motor activity but cannot show a spatial correlation. The diagnostic value of EGG is poor, but EGG may have some value for the identification of patients with STC.
文摘This paper reports a study of complex focussing acoustic fields of a convex phased array probe widely used in ultrasonic diagnostic B-scanner. The time delay necessary for electronic focussing and for geometric focussing of complex focussing is given. By means of Helmholtz's integral formula, the expressions of acoustic fields were obtained for the electronic focussing and complex focussing.With Simpson's numerical integral, a great deal of computations was carried out with an 86 / 330 computer. By means of using different parameters, an optimum focal range and beam width of a 4 sequences electronic and complex focussing acoustic system was selected. With an EUB-40 ultrasound diagnostic B-scanner produced by the Hitachi company, the lateral focussing acoustic field and lateral resolution in an echoic tank were photographed by latticing method and the experimental result is consistent with the theory.
文摘Objective To compare the diagnostic efficiency of the thyroid imaging reporting and data system(TIRADS),the Bethesda system for reporting thyroid cytopathology(BSRTC)and BRAFV600Edetection,and their combined use in the differentiation between benign and malignant thyroid nodules.Methods One hundred
文摘目的用 Meta 分析方法研究^(18)F-FDG PET 在结直肠癌复发诊断中的价值,并探讨其主要的误诊原因。方法收集2007年2月8日前公开发表的关于 PET 对结直肠癌术后复发评估的所有中英文文献,对纳入文献进行方法学质量评估后,用统计软件计算综合灵敏度(Se)、特异性(Sp)、诊断优势比(DOR),并绘制综合受试者工作特征(SROC)曲线。结果共有19篇文献纳入。PET评价结直肠癌全身复发及转移的综合 Se 为89.5%[95%可信区间(CI)86.6%～92.0%],综合 Sp为78.3%(95%CI 72.0%～83.8%),综合 DOR 为28.114(95%CI 12.120～65.216);SROC 曲线下面积为0.8857,Q~*值为0.8163。结论 ^(18)F-FDG PET 在结直肠癌术后复发诊断中有较高的价值。
文摘目的孤立性肺结节(solitary pulmonary nodule,SPN)的定性诊断十分困难,PET/CT是目前评价良、恶性病变最具优势的影像学手段之一。文中用Meta分析方法综合评价18F-脱氧葡萄糖(18Fluorodexglucose,FDG)PET/CT显像诊断恶性孤立性肺结节的价值。方法以孤立性肺结节、FDG、PET/CT等为检索词,检索1994年1月至2009年7月的Medline数据库、西文生物医学期刊文献服务系统、外文生物医学期刊全文数据库、中国学术期刊网全文数据库等相关中英文文献。对符合标准的研究进行质量评估,用MetaDisc1.4软件进行异质性检验,综合敏感性、特异性和诊断优势比,绘制汇总受试者工作特征(summary receiver operating characteristic,SROC)曲线和计算曲线下面积(the area under the curve,AUC),并进行敏感性分析。结果共检索相关文献29篇,其中11篇符合标准纳入分析,A级1篇,B级10篇,各研究之间存在异质性,按照随机效应模型合并敏感性、特异性、诊断优势比(diagnostic odds ratio,DOR)及其95%可信区间分别为91%(87%~93%)、83%(78%~87%)和51.04(23.33~111.66),AUC为0.9383,Q值为0.875 3,纳入文献稳定性较好。结论 18F-FDG PET/CT显像能灵敏、准确地诊断恶性孤立性肺结节,具有较高的临床应用价值。
文摘AIM: To assess if certain triaging rules could be established to optimize the yield of mesenteric angiography. METHODS: Medical records of 101 patients were retrospectively reviewed and parameters relating to age, gender, pulse rate, blood pressure, serum hemoglobin, intensive care unit(ICU) admission, and the number of packed red blood cells(PRBC) transfused in the 12 and 24 h prior to the angiography were tabulated in two groups with positive and negative angiography results. RESULTS: We found no correlation between gender, pulse rate, blood pressure or serum hemoglobin and positivity of the mesenteric angiogram. But patients with positive angiogram were found to be on average 7 years older(73.2 years vs 65.9 years old)(P = 0.02). Angiogram was positive in 39.3 %(11/28) of patientsadmitted in ICU vs 23.2%(17/73) who were admitted elsewhere in the hospital(P = 0.03). In the 12 and 24 h prior to angiography, patients with a positive angiogram received a mean of 2.7 ± 2.3 and 3.3 ± 2.6 units of PRBC s respectively, while patients with a negative angiogram had a mean of 1.6 ± 1.9(P = 0.02) and 2.1 ± 2.6 units(P = 0.04) received respectively in the same period. CONCLUSION: Older age, ICU admission, having received at least 4 units PRBC over 12 h or 5 units over 24 h prior to angiogram are leading indicators for a positive study.
文摘Objective To investigate the role of dobutamine stree echocardiography in evaluating cardiac betaadrenergic receptor (AR) function and responsive ness in children Methods Left ventricular ejection fraction (EF), fractional shortening (FS), left ventricular end systolic volume index (ESVI), the ratio of systolic b lood pressure and ESVI (SP/ESVI) were measured by dobutamine stress echocardiogr aphy (DSE) in 30 children with AR hypersensitivity, 15 children with dilated cardiomyopathy and 30 normal children respectively Results Before pharmacological stress, EF and FS were 072 and 039 r es pectively in AR hypersensitivity group versus 070 and 035 respectively i n control group There was no difference of the indices between the two groups ( P >005) SP/ESVI was 076, higher than the value of 066 in co ntro l group ( P <005); EF, FS and SP/ESVI were 041, 015 and 01 0 re spectively, which were significantly lower than those in control group After d o butamine stress of 5?gkg-1min-1 and 10?gkg-1min -1, EF, FS and SP/ESVI were sig nificantly increased in patients with AR hypersensitivity and there were no changes in children with dilated cardiomyopathy compared with values of baseline Conclusion Cardiac AR function and responsiveness can be evaluated by dobutamine stress echocardiography
