The Carboniferous prototype sedimentary basin in the Tazhong (Central Tarimbasin) area is recognized as a compressive intracratonic depressional one. Three type Ⅰ sequenceboundaries and three type Ⅱ sequence boundar...The Carboniferous prototype sedimentary basin in the Tazhong (Central Tarimbasin) area is recognized as a compressive intracratonic depressional one. Three type Ⅰ sequenceboundaries and three type Ⅱ sequence boundaries can be identified in the CarboniferousSystem, which can accordingly be divided into five sedimentary sequences. These sequencespossess stratigraphic characters of the standard sequence and correspond to the depositionalstratigraphic unit of a third-order eustatic cycle. They can be regionally or globally correlatedwith each other. The framework of sequence stratigraphy of the intracratonict basin in thestudy area distinctly differs from that of the passive continental-margin basin in the lack ofdepositional systems of early-middle lowstand, poor development of the deeply incised valleyand condensed section of the maximum sea-flood, good development of type Ⅱ sequenceboundaries and coastal plain depositional systems coexisting with shelf-type fan deltas underwet climatic conditions, Which consequently led to the formation of a paralic lithofacies frame-work.展开更多
The objective of this study is to quantify the puerarin in rat plasma following oral administration of TZ18 and compare the pharmacokinetics characteristics of puerarin in normal rats with that in depression model rat...The objective of this study is to quantify the puerarin in rat plasma following oral administration of TZ18 and compare the pharmacokinetics characteristics of puerarin in normal rats with that in depression model rats. A high performance liquid chromatography method was used to quantify the puerarin due to its good selectivity and linearity （coefficient correlation, r^2 = 0.9991） within the tested range （0.028-0.889 μg·mL^-1）- Intra- and inter-day precision coefficients of variation and accuracy bias were acceptable （Maximum coefficient of variation was 5.74% for intra-day and 3.09% for inter-day） over the entire range. The recoveries were found to be 98.3%, 101.4%, and 103.4% for concentrations of 0.028, 0.222, and 0.444 μg · mL^-1, respectively. The concentration-time curves for both normal rats and depression model rats were fit to a twocompartment model with the first order absorption. The results show significant differences in the main pharmacokinetic parameters of peak time, peak concentration, and the area under the concentration-time curve between the two kinds of rats.展开更多
文摘The Carboniferous prototype sedimentary basin in the Tazhong (Central Tarimbasin) area is recognized as a compressive intracratonic depressional one. Three type Ⅰ sequenceboundaries and three type Ⅱ sequence boundaries can be identified in the CarboniferousSystem, which can accordingly be divided into five sedimentary sequences. These sequencespossess stratigraphic characters of the standard sequence and correspond to the depositionalstratigraphic unit of a third-order eustatic cycle. They can be regionally or globally correlatedwith each other. The framework of sequence stratigraphy of the intracratonict basin in thestudy area distinctly differs from that of the passive continental-margin basin in the lack ofdepositional systems of early-middle lowstand, poor development of the deeply incised valleyand condensed section of the maximum sea-flood, good development of type Ⅱ sequenceboundaries and coastal plain depositional systems coexisting with shelf-type fan deltas underwet climatic conditions, Which consequently led to the formation of a paralic lithofacies frame-work.
文摘The objective of this study is to quantify the puerarin in rat plasma following oral administration of TZ18 and compare the pharmacokinetics characteristics of puerarin in normal rats with that in depression model rats. A high performance liquid chromatography method was used to quantify the puerarin due to its good selectivity and linearity （coefficient correlation, r^2 = 0.9991） within the tested range （0.028-0.889 μg·mL^-1）- Intra- and inter-day precision coefficients of variation and accuracy bias were acceptable （Maximum coefficient of variation was 5.74% for intra-day and 3.09% for inter-day） over the entire range. The recoveries were found to be 98.3%, 101.4%, and 103.4% for concentrations of 0.028, 0.222, and 0.444 μg · mL^-1, respectively. The concentration-time curves for both normal rats and depression model rats were fit to a twocompartment model with the first order absorption. The results show significant differences in the main pharmacokinetic parameters of peak time, peak concentration, and the area under the concentration-time curve between the two kinds of rats.
