Most planned developments in a catchment for control of excess water using a culvert, bridge or dam spillway are located at a site in a stream where there are no discharge measurements. Even though, for gauged catchme...Most planned developments in a catchment for control of excess water using a culvert, bridge or dam spillway are located at a site in a stream where there are no discharge measurements. Even though, for gauged catchments a number of established flood frequency models and rainfall-runoff models do exist, for ungauged catchments mostly regional flood frequency and event-based rainfall-runoff models are used, which depend on regional parameters. In this paper, a regional approach for design floods is presented and risk implication for design of drainage structures assessed. A case study in light of the above has been considered at four ungauged sites in the Limpopo Drainage Basin in north-eastern Botswana.展开更多
This paper introduces a web-based application that enables engineers or designers to identify risks during the conceptual phase of a product design. This software application was developed based on the Risk in Early D...This paper introduces a web-based application that enables engineers or designers to identify risks during the conceptual phase of a product design. This software application was developed based on the Risk in Early Design (RED) method developed by Author, Stone, and Tumer. The RED method demonstrates that risks can be identified in the early phase of product design by relating recorded historical failure information to product functions. Based on the concept of RED theory and current industry needs, the goals of a web-based RED application were defined. These goals are the intended benefits or functionalities that the web-based RED application would provide. In addition, a multi-level evaluation framework was adopted to determine how well the application meets the needs of various organizations. As part of the evaluation, a questionnaire was developed and administered to a sample industrial and academic user group. The results of the evaluation indicate that the web-based RED software application meets many of the goals to help an organization in performing product risk analysis.展开更多
An overview of the GeoSafe 2016 Symposium topic is provided using the example of large concrete dams for purposes of illustration.It is essential that the risks associated with large dams be evaluated rigorously and m...An overview of the GeoSafe 2016 Symposium topic is provided using the example of large concrete dams for purposes of illustration.It is essential that the risks associated with large dams be evaluated rigorously and managed proactively at all stages of their lives so that the risk of failure remains As Low As Reasonably Practicable(ALARP).Rock engineering features of large concrete dams that require particular attention,assessment and monitoring during the investigation,design,construction,initial filling,inservice operation,and subsequent repair and upgrade stages of the lives of concrete dams are identified and illustrated by examples from recorded experiences.A number of major concrete dam failures,including that of the St.Francis dam,California,U.S.A.,in 1928,have led to significant developments in rock mechanics and rock engineering knowledge and techniques,as well as in dam design and review processes.More recent advances include a range of analytical,numerical modelling,probabilistic,reliability,failure mode and risk assessment approaches.展开更多
The study was carried out exclusively in Ghana to explore the approaches employed by consultants in risk assessment at the design phase of projects in Ghana. One hundred and fourteen (114) consultants were selected ou...The study was carried out exclusively in Ghana to explore the approaches employed by consultants in risk assessment at the design phase of projects in Ghana. One hundred and fourteen (114) consultants were selected out of a population of one hundred and eighty six (186) from three main professional associations in Ghana made up of the Ghana Institute of Architects, Ghana Institution of Engineers and the Ghana Institution of Surveyors (Quantity Surveying Division) practicing in Ghana for the study. Both primary and secondary data were collected. A descriptive survey was also used to observe and describe the presence, frequency or absence of characteristics of a phenomenon as it naturally occurred, in order to gain additional information. A questionnaire was also designed to collect data from the architects, engineers and quantity surveyors. The data was analyzed using Statistical Package for the Social Scientists (SPSS) 17.0. Descriptive and inferential statistics, such as frequency tables, percentages and cross tabulations were used in the data analysis and summaries. Simple tests of associations were undertaken by using Chi square and Cramer’s V statistics to compare relationships between variables. Again, relative importance index was also used to analyze some of the data by computing to deduce their rankings. The relative importance index was used to analyze some of the data by computing to deduce their rankings. The research revealed that majority of consultants had an average knowledge of risk management. Based on the findings it was recommended that consultants undergo advanced training in risk assessment. It was therefore suggested that consultancy firms should develop a set of laid down procedures for consultants to use in risk assessment in order that the use of intuition employed by majority is lessened. The challenges observed in risk assessment and the remedial steps suggested curtailing the detrimental effects of risks would be of wide importance to many developing economies.展开更多
This paper presents a methodology for automatically generating risk scenarios for dynamic reliability applications in which some dynamic characteristics(e.g.,the order,timing and magnitude of events,the value of relev...This paper presents a methodology for automatically generating risk scenarios for dynamic reliability applications in which some dynamic characteristics(e.g.,the order,timing and magnitude of events,the value of relevant process parameters and initial conditions) have a significant influence on the evolution of the system.The main idea of the methodology is:(i) making the system model "express itself" through simulation by having the model driven by an elaborated simulation engine;(ii) exploiting uniform design to pick out a small subset of representative design points from the space of relevant dynamic characteristics;(iii) for each selected design point,employing a depth-first systematic exploration strategy to cover all possible scenario branches at each branch point.A highly dynamic example adapted from the literature(a chemical batch reactor) is studied to test the effectiveness of the proposed methodology.展开更多
This paper describes the development of a T-year design tide hydrograph (DTH). A core innovation is that the proposed technique uses the design risk threshold and copula-based conditional risk probability to analyze...This paper describes the development of a T-year design tide hydrograph (DTH). A core innovation is that the proposed technique uses the design risk threshold and copula-based conditional risk probability to analyze the optimal combination of high waters and low waters of the DTH. A brief description of the method is presented. The in situ semi-diurnal tide data at the coast of Jiangsu Province in China are analyzed. Marginal distributions for high waters and low waters of tides are examined. Furthermore, the joint distributions, condition risk probabilities and risk thresholds of high waters and low waters are presented. Results of the DTH from the proposed method are compared with those from the traditional same-multiple enlarging design approach. It is demonstrated that the proposed method is preferable.展开更多
Most of the important units of pressure equipment have been manufactured successfully in China related to the national key construction projects,such as 10 million tons/year oil refinery,million tons/year ethylene,lar...Most of the important units of pressure equipment have been manufactured successfully in China related to the national key construction projects,such as 10 million tons/year oil refinery,million tons/year ethylene,large coal chemical,etc.However,some of them failed to operate shortly after their putting into service.Some suffered severe damage even during the previous period of manufacture and installation.In this paper,cases of accident survey and failure analysis are given for some typical pressure vessels.It is found that many accidents are related to insufficient consideration of the design and manufacture of the equipment.These accidents occur fundamentally because of the Chinese design standards codes for pressure equipment without risk or life concepts and the support from a database for potential risk existing in their dynamic service.Most designers and manufacturers are unable to make correct design,materials selection and manufacturing process all due to a lack of engineering experience.In order to avoid the repetition of the accidents and improve the safety,reliability and economy of pressure equipment,a platform is suggested for design,manufacture and maintenance of pressure equipment in China based on accidents survey.In other words,some effective precautionary measures are taken at the design and manufacture stage,and the design methodology has to be based on service life requirement and desirable risk level.At the service stage some reasonable inspection/monitoring approaches should be utilized to control risks and ensure the equipment operating safely until its desired lifespan.Finally,the basic scheme and some key technologies are briefly given for the platform construction.The concept of risk and life based design,manufacture and maintenance proposed herein has important significance for improving and perfecting the codes and standards for design,manufacture and maintenance of Chinese pressure-bearing equipment,enhancing the life and reliability of Chinese pressure-bearing equipment and promoting the development of in-service maintenance technology that combines safety and economy.展开更多
Many years experience of the operation of high stress (>72% specified minimum yield strength, SMYS) gas pipelines and statistical analysis results of pipeline incidents showed that the operating pipelines at stress...Many years experience of the operation of high stress (>72% specified minimum yield strength, SMYS) gas pipelines and statistical analysis results of pipeline incidents showed that the operating pipelines at stress levels over 72% SMYS have not presented problems in USA and Canada, and design factor does not control incidents or the safety of pipelines. Enhancing pipeline safety management level is most important for decreasing incident rate. The application history of higher design factors in the U.S and Canada was reviewed. And the effect of higher factors to the critical flaw size, puncture resistance, change of reliability with time, risk level and the arrest toughness requirements of pipeline were analyzed here. The comparison of pipeline failure rates and risk levels between two design factors (0.72 and 0.8) has shown that a change in design factor from 0.72 to 0.8 would bring little effect on failure rates and risk levels. On the basis of the analysis result, the application feasibility of design factor of 0.8 in China was discussed and the related suggestions were proposed. When an operator wishes to apply design factor 0.8 to gas pipeline, the following process is recommended: stress level of line pipe hydro test should be up to 100% SMYS, reliability and risk assessment at the design feasibility or conceptual stage should be conducted, Charpy impact energy should meet the need of pipeline crack arrest; and establish and execute risk based integrity management plan. The technology of pipeline steel metallurgy, line pipe fabrication and pipeline construction, and line pipe quality control level in China achieved tremendous progresses, and line pipe product standards and property indexes have come up to international advanced level. Furthermore, pipeline safety management has improved greatly in China. Consequently, the research for the feasibility of application of design factor of 0.8 in China has fundamental basis.展开更多
Engineering designs for mountainous highways emphasize compliance checking to ensure safety. However, relying solely on compliance checking may lead designers to minimize costs at the expense of high risk indicators, ...Engineering designs for mountainous highways emphasize compliance checking to ensure safety. However, relying solely on compliance checking may lead designers to minimize costs at the expense of high risk indicators, since the overall risk level of the highway design is unknown to the designers. This paper describes a method for the simultaneous consideration of traffic safety risks and the associated cost burden related to the appropriate planning and design of a mountainous highway. The method can be carried out in four steps: First, the highway design is represented by a new parametric framework to extract the key design variables that affect not only the life-cycle cost but also the operational safety. Second, the relationship between the life-cycle cost and the operational safety risk factors is established in the cost-estimation functions. Third, a fault tree analysis (FTA) is introduced to identify the traffic risk factors from the design variables. The safety performance of the design solutions is also assessed by the generalized linear-regression model. Fourth, a theory of acceptable risk analysis is introduced to the traffic safety assessment, and a computing algorithm is proposed to solve for a cost-efficient optimal solution within the range of acceptable risk, in order to help decision-makers. This approach was applied and examined in the Sichuan–Tibet Highway engineering project, which is located in a complex area with a large elevation gradient and a wide range of mountains. The experimental results show that the proposed approach significantly improved both the safety and cost performance of the project in the study area.展开更多
Quality by Test was the only way to guarantee quality of drug products before FDA launched current Good Manufacturing Practice. To clearly understand the manufacture processes, FDA generalized Quality by Design(QbD) i...Quality by Test was the only way to guarantee quality of drug products before FDA launched current Good Manufacturing Practice. To clearly understand the manufacture processes, FDA generalized Quality by Design(QbD) in the field of pharmacy, which is based on the thorough understanding of how materials and process parameters affect the quality profile of final products. The application of QbD in drug formulation and process design is based on a good understanding of the sources of variability and the manufacture process. In this paper,the basic knowledge of QbD, the elements of QbD, steps and tools for QbD implementation in pharmaceutics field, including risk assessment, design of experiment, and process analytical technology(PAT), are introduced briefly. Moreover, the concrete applications of QbD in various pharmaceutical related unit operations are summarized and presented.展开更多
Under the condition of asymmetric information,the Spence 's Job Market Signaling Model is generally applied to inspect the design capability of a designer and his labor and efforts to be invested; however,since th...Under the condition of asymmetric information,the Spence 's Job Market Signaling Model is generally applied to inspect the design capability of a designer and his labor and efforts to be invested; however,since the"prior probability"and "posterior probability"have great uncertainties,the practical effect of this model is poor. On the basis of analyzing reverse selection questions,this paper provides a design capability screening model,which can make a designer automatically expose his hidden information so that necessary actions can be taken as required by the owner to realize risk sharing. A calculation example is finally given to demonstrate that the new model is helpful for an owner to select a designer with high professional level and to lead the designer to work hard,so it is of significant application value.展开更多
Effect sizes are estimated from several study designs when the subjects are individually sampled. When the samples are the aggregate cluster of individuals, the within cluster correlation must be accounted for to cons...Effect sizes are estimated from several study designs when the subjects are individually sampled. When the samples are the aggregate cluster of individuals, the within cluster correlation must be accounted for to construct correct confidence intervals, and to conduct valid statistical inference. The purpose of this article is to propose and evaluate statistical procedures for the estimation of the variance of the estimated attributable risk in parallel groups of clusters, and in a design dividing each of k clusters into two segments creating multiple sub-clusters. The estimated variance is the first order approximation and is obtained by the delta method. We apply the methodology and propose a Wald type confidence interval on the difference between two correlated attributable risks. We also construct a test on the hypothesis of equality of two correlated attributable risks. We evaluate the power of the proposed test via Monte-Carlo simulations.展开更多
文摘Most planned developments in a catchment for control of excess water using a culvert, bridge or dam spillway are located at a site in a stream where there are no discharge measurements. Even though, for gauged catchments a number of established flood frequency models and rainfall-runoff models do exist, for ungauged catchments mostly regional flood frequency and event-based rainfall-runoff models are used, which depend on regional parameters. In this paper, a regional approach for design floods is presented and risk implication for design of drainage structures assessed. A case study in light of the above has been considered at four ungauged sites in the Limpopo Drainage Basin in north-eastern Botswana.
文摘This paper introduces a web-based application that enables engineers or designers to identify risks during the conceptual phase of a product design. This software application was developed based on the Risk in Early Design (RED) method developed by Author, Stone, and Tumer. The RED method demonstrates that risks can be identified in the early phase of product design by relating recorded historical failure information to product functions. Based on the concept of RED theory and current industry needs, the goals of a web-based RED application were defined. These goals are the intended benefits or functionalities that the web-based RED application would provide. In addition, a multi-level evaluation framework was adopted to determine how well the application meets the needs of various organizations. As part of the evaluation, a questionnaire was developed and administered to a sample industrial and academic user group. The results of the evaluation indicate that the web-based RED software application meets many of the goals to help an organization in performing product risk analysis.
文摘An overview of the GeoSafe 2016 Symposium topic is provided using the example of large concrete dams for purposes of illustration.It is essential that the risks associated with large dams be evaluated rigorously and managed proactively at all stages of their lives so that the risk of failure remains As Low As Reasonably Practicable(ALARP).Rock engineering features of large concrete dams that require particular attention,assessment and monitoring during the investigation,design,construction,initial filling,inservice operation,and subsequent repair and upgrade stages of the lives of concrete dams are identified and illustrated by examples from recorded experiences.A number of major concrete dam failures,including that of the St.Francis dam,California,U.S.A.,in 1928,have led to significant developments in rock mechanics and rock engineering knowledge and techniques,as well as in dam design and review processes.More recent advances include a range of analytical,numerical modelling,probabilistic,reliability,failure mode and risk assessment approaches.
文摘The study was carried out exclusively in Ghana to explore the approaches employed by consultants in risk assessment at the design phase of projects in Ghana. One hundred and fourteen (114) consultants were selected out of a population of one hundred and eighty six (186) from three main professional associations in Ghana made up of the Ghana Institute of Architects, Ghana Institution of Engineers and the Ghana Institution of Surveyors (Quantity Surveying Division) practicing in Ghana for the study. Both primary and secondary data were collected. A descriptive survey was also used to observe and describe the presence, frequency or absence of characteristics of a phenomenon as it naturally occurred, in order to gain additional information. A questionnaire was also designed to collect data from the architects, engineers and quantity surveyors. The data was analyzed using Statistical Package for the Social Scientists (SPSS) 17.0. Descriptive and inferential statistics, such as frequency tables, percentages and cross tabulations were used in the data analysis and summaries. Simple tests of associations were undertaken by using Chi square and Cramer’s V statistics to compare relationships between variables. Again, relative importance index was also used to analyze some of the data by computing to deduce their rankings. The relative importance index was used to analyze some of the data by computing to deduce their rankings. The research revealed that majority of consultants had an average knowledge of risk management. Based on the findings it was recommended that consultants undergo advanced training in risk assessment. It was therefore suggested that consultancy firms should develop a set of laid down procedures for consultants to use in risk assessment in order that the use of intuition employed by majority is lessened. The challenges observed in risk assessment and the remedial steps suggested curtailing the detrimental effects of risks would be of wide importance to many developing economies.
基金supported by the National Natural Science Foundation of China (70901004)the Fundamental Research Funds for the Central Universities (YWF-10-01-A12)
文摘This paper presents a methodology for automatically generating risk scenarios for dynamic reliability applications in which some dynamic characteristics(e.g.,the order,timing and magnitude of events,the value of relevant process parameters and initial conditions) have a significant influence on the evolution of the system.The main idea of the methodology is:(i) making the system model "express itself" through simulation by having the model driven by an elaborated simulation engine;(ii) exploiting uniform design to pick out a small subset of representative design points from the space of relevant dynamic characteristics;(iii) for each selected design point,employing a depth-first systematic exploration strategy to cover all possible scenario branches at each branch point.A highly dynamic example adapted from the literature(a chemical batch reactor) is studied to test the effectiveness of the proposed methodology.
基金financially supported by the Ministry of Water Resources Special Funds for Scientific Research Projects of Public Welfare Industry(Grant No.201001070)Jiangsu Province Science and Technology(Grant Nos.BM2014397 and BM2016031)
文摘This paper describes the development of a T-year design tide hydrograph (DTH). A core innovation is that the proposed technique uses the design risk threshold and copula-based conditional risk probability to analyze the optimal combination of high waters and low waters of the DTH. A brief description of the method is presented. The in situ semi-diurnal tide data at the coast of Jiangsu Province in China are analyzed. Marginal distributions for high waters and low waters of tides are examined. Furthermore, the joint distributions, condition risk probabilities and risk thresholds of high waters and low waters are presented. Results of the DTH from the proposed method are compared with those from the traditional same-multiple enlarging design approach. It is demonstrated that the proposed method is preferable.
基金supported by Sino-France National International Cooperation Program(Grant No.2006DFB73000)National High-tech Research and Development Program of China(863 Program, Grant No.2007AAO4Z430,Grant No.2009AA044802)
文摘Most of the important units of pressure equipment have been manufactured successfully in China related to the national key construction projects,such as 10 million tons/year oil refinery,million tons/year ethylene,large coal chemical,etc.However,some of them failed to operate shortly after their putting into service.Some suffered severe damage even during the previous period of manufacture and installation.In this paper,cases of accident survey and failure analysis are given for some typical pressure vessels.It is found that many accidents are related to insufficient consideration of the design and manufacture of the equipment.These accidents occur fundamentally because of the Chinese design standards codes for pressure equipment without risk or life concepts and the support from a database for potential risk existing in their dynamic service.Most designers and manufacturers are unable to make correct design,materials selection and manufacturing process all due to a lack of engineering experience.In order to avoid the repetition of the accidents and improve the safety,reliability and economy of pressure equipment,a platform is suggested for design,manufacture and maintenance of pressure equipment in China based on accidents survey.In other words,some effective precautionary measures are taken at the design and manufacture stage,and the design methodology has to be based on service life requirement and desirable risk level.At the service stage some reasonable inspection/monitoring approaches should be utilized to control risks and ensure the equipment operating safely until its desired lifespan.Finally,the basic scheme and some key technologies are briefly given for the platform construction.The concept of risk and life based design,manufacture and maintenance proposed herein has important significance for improving and perfecting the codes and standards for design,manufacture and maintenance of Chinese pressure-bearing equipment,enhancing the life and reliability of Chinese pressure-bearing equipment and promoting the development of in-service maintenance technology that combines safety and economy.
基金supported by China National Petroleum Corporation Application Fundamental Research Foundation (Grant No. 07A40401)
文摘Many years experience of the operation of high stress (>72% specified minimum yield strength, SMYS) gas pipelines and statistical analysis results of pipeline incidents showed that the operating pipelines at stress levels over 72% SMYS have not presented problems in USA and Canada, and design factor does not control incidents or the safety of pipelines. Enhancing pipeline safety management level is most important for decreasing incident rate. The application history of higher design factors in the U.S and Canada was reviewed. And the effect of higher factors to the critical flaw size, puncture resistance, change of reliability with time, risk level and the arrest toughness requirements of pipeline were analyzed here. The comparison of pipeline failure rates and risk levels between two design factors (0.72 and 0.8) has shown that a change in design factor from 0.72 to 0.8 would bring little effect on failure rates and risk levels. On the basis of the analysis result, the application feasibility of design factor of 0.8 in China was discussed and the related suggestions were proposed. When an operator wishes to apply design factor 0.8 to gas pipeline, the following process is recommended: stress level of line pipe hydro test should be up to 100% SMYS, reliability and risk assessment at the design feasibility or conceptual stage should be conducted, Charpy impact energy should meet the need of pipeline crack arrest; and establish and execute risk based integrity management plan. The technology of pipeline steel metallurgy, line pipe fabrication and pipeline construction, and line pipe quality control level in China achieved tremendous progresses, and line pipe product standards and property indexes have come up to international advanced level. Furthermore, pipeline safety management has improved greatly in China. Consequently, the research for the feasibility of application of design factor of 0.8 in China has fundamental basis.
基金the National Natural Science Foundation of China (71732001, 51878311, and 51678265)the Research Project of the Chinese Academy of Engineering (2017-XZ-12).
文摘Engineering designs for mountainous highways emphasize compliance checking to ensure safety. However, relying solely on compliance checking may lead designers to minimize costs at the expense of high risk indicators, since the overall risk level of the highway design is unknown to the designers. This paper describes a method for the simultaneous consideration of traffic safety risks and the associated cost burden related to the appropriate planning and design of a mountainous highway. The method can be carried out in four steps: First, the highway design is represented by a new parametric framework to extract the key design variables that affect not only the life-cycle cost but also the operational safety. Second, the relationship between the life-cycle cost and the operational safety risk factors is established in the cost-estimation functions. Third, a fault tree analysis (FTA) is introduced to identify the traffic risk factors from the design variables. The safety performance of the design solutions is also assessed by the generalized linear-regression model. Fourth, a theory of acceptable risk analysis is introduced to the traffic safety assessment, and a computing algorithm is proposed to solve for a cost-efficient optimal solution within the range of acceptable risk, in order to help decision-makers. This approach was applied and examined in the Sichuan–Tibet Highway engineering project, which is located in a complex area with a large elevation gradient and a wide range of mountains. The experimental results show that the proposed approach significantly improved both the safety and cost performance of the project in the study area.
基金financially supported by Talents Project of Liaoning Province, China (LR2013047)
文摘Quality by Test was the only way to guarantee quality of drug products before FDA launched current Good Manufacturing Practice. To clearly understand the manufacture processes, FDA generalized Quality by Design(QbD) in the field of pharmacy, which is based on the thorough understanding of how materials and process parameters affect the quality profile of final products. The application of QbD in drug formulation and process design is based on a good understanding of the sources of variability and the manufacture process. In this paper,the basic knowledge of QbD, the elements of QbD, steps and tools for QbD implementation in pharmaceutics field, including risk assessment, design of experiment, and process analytical technology(PAT), are introduced briefly. Moreover, the concrete applications of QbD in various pharmaceutical related unit operations are summarized and presented.
基金Sponsored by State Key Laboratory of Subtropical Building Science,Autonomous Research Topics(Grant No.x2tjc7100870)
文摘Under the condition of asymmetric information,the Spence 's Job Market Signaling Model is generally applied to inspect the design capability of a designer and his labor and efforts to be invested; however,since the"prior probability"and "posterior probability"have great uncertainties,the practical effect of this model is poor. On the basis of analyzing reverse selection questions,this paper provides a design capability screening model,which can make a designer automatically expose his hidden information so that necessary actions can be taken as required by the owner to realize risk sharing. A calculation example is finally given to demonstrate that the new model is helpful for an owner to select a designer with high professional level and to lead the designer to work hard,so it is of significant application value.
文摘Effect sizes are estimated from several study designs when the subjects are individually sampled. When the samples are the aggregate cluster of individuals, the within cluster correlation must be accounted for to construct correct confidence intervals, and to conduct valid statistical inference. The purpose of this article is to propose and evaluate statistical procedures for the estimation of the variance of the estimated attributable risk in parallel groups of clusters, and in a design dividing each of k clusters into two segments creating multiple sub-clusters. The estimated variance is the first order approximation and is obtained by the delta method. We apply the methodology and propose a Wald type confidence interval on the difference between two correlated attributable risks. We also construct a test on the hypothesis of equality of two correlated attributable risks. We evaluate the power of the proposed test via Monte-Carlo simulations.