An Optimal Policy with Quadratic Demand, Three-Parameter Weibull Distribution Deterioration Rate, Shortages and Salvage Value

The present paper focuses an optimal policy of an inventory model for deteriorating items with generalized demand rate and deterioration rate. Shortages are allowed and partially backlogged. The salvage value is included into deteriorated units. The main objective of the model is to minimize the total cost by optimizing the value of the shortage point, cycle length and order quantity. A numerical example is carried out to illustrate the model and sensitivity analyses of major parameters are discussed.

Cold supply chain inventory models for agricultural products with multi-stage stochastic deterioration rates

In India,majority of the families depend upon agricultural business.Also,40%of agricultural food and vegetables are rotted due to improper planning.It is predicted in 2023 that US$293.27 billions will be wastage of food.That’s why,the cost of these items are high in the retail market and farmers get least price for their produce.It is essential to avoid the loss by adopting cold supply chain and its impact will help to increase the GDP of country.Here,we proposed the supply chain model which includes one warehouse and multi-retailers.Cold storage facility is available at warehouse,transport facility and retailers.To support the proposed model,we have collected the numerical data of coriander(highly perishable)product from the market yard,Pune,India.The proposed model solved by using real world numerical case study.The life of this product is very less hence it needs to develop a cold supply chain for this item.Also,we solved multiple inventory differential equations by using boundary value problem.To solve the proposed models for single retailer and multiple retailers,we have developed a solution methodology based on evolutionary algorithm.We have observed that,optimum profit is highly sensitive to the warehouse demand and purchase cost.Hence it is essential to reduce the deteriorated items at storage point.The warehouse,retailer and customer demand significantly affect on the deteriorated items.In single and multiple retailer,for low warehouse and retailer demand,we get maximum profit.Thus,less number of deteriorated items of the supply chain will helps to the society,as well as country to increase the profit of the supply chain.

Characteristics of language impairment in Parkinson’s disease and its influencing factors

Background:Language impairment is relatively common in Parkinson’s disease(PD),but not all PD patients are susceptible to language problems.In this study,we identified among a sample of PD patients those pre-disposed to language impairment,describe their clinical profiles,and consider factors that may precipitate language disability in these patients.Methods:A cross-sectional cohort of 31 PD patients and 20 controls were administered the Chinese version of the Western Aphasia Battery(WAB)to assess language abilities,and the Montreal Cognitive Assessment(MoCA)to determine cognitive status.PD patients were then apportioned to a language-impaired PD(LI-PD)group or a PD group with no language impairment(NLI-PD).Performance on the WAB and MoCA was investigated for correlation with the aphasia quotient deterioration rate(AQDR).Results:The PD patients scored significantly lower on most of the WAB subtests than did the controls.The aphasia quotient,cortical quotient,and spontaneous speech and naming subtests of the WAB were significantly different between LI-PD and NLI-PD groups.The AQDR scores significantly and positively correlated with age at onset and motor function deterioration.Conclusion:A subset group was susceptible to language dysfunction,a major deficit in spontaneous speech.Once established,dysphasia progression is closely associated with age at onset and motor disability progression.