Organic carbon isotope and pollen evidence for mangrove development and response to human activity in Guangxi(Southwest China) over the last 140 years

Mangrove degradation must reduce carbon sequestration in recent years, thereby aggravating global warming.Thus, short-term impacts of human activity on mangrove ecosystems are cause for concern from local governments and scientists. Mangroves sediments can provide detailed records of mangrove species variation in the last one hundred years, based on detailed 210 Pb data. The study traced the history of mangrove development and its response to environmental change over the last 140 years in two mangrove swamps of Guangxi, Southwest China. Average sedimentation rates were calculated to be 0.48 cm/a and 0.56 cm/a in the Yingluo Bay and the Maowei Sea, respectively. Chemical indicators（δ13Corg and C：N） were utilized to trace the contribution of mangrove-derived organic matter（MOM） using a ternary mixing model. Simultaneous use of mangrove pollen can help to supplement some of these limitations in diagenetic/overlap of isotopic signatures. We found that vertical distribution of MOM was consistent with mangrove pollen, which could provide similar information for tracing mangrove ecosystems. Therefore, mangrove development was reconstructed and divided into three stages： flourishing, degradation and re-flourishing/re-degradation period. The significant degradation, found in the period of 1968–1998 and 1907–2007 in the Yingluo Bay and the Maowei Sea, respectively, corresponding to a rapid increase of reclamation area and seawall length, rather than climate change as recorded in the region.

Developmental Lead Exposure Alters the Distribution of Protein Kinase C Activity in the Rat Hippocampus

Chronic low-level lead (Pb) exposure in children is known to cause a deficit in learning and memory. In vitro studies have demonstrated that Pb altered protein kinase C (PKC) activityt Especially, hippocampal PKC has been correlated with performance in several learning tasks. The effects of Pb exposure on hippocampal PKC were investigated during development at various postnatal ages: postnatal day (PN) 7, 14, 28, and 56. Two-tenth % Pb acetate was administered to pregnant and lactating dams and then administered to weanling rats in drinking water. PKC activity was measured in both membrane and cytosolic fractions from the hippocampi of the controls and Pb-exposed animals. Pb-induced increase in PKC activity in the cytosolic fraction was obsereved in the PN56 rats. In contrast, PKC activity was decreased by Pb at PN7 in the membrane fraction. Furthermore, a significant decrease in the ratio of membrane to cytosolic PKC activity which is representative of PKC distribution was observed in the PN28 and PN56 Pb-exposed rats relative to the same-age controls. This study indicates that chronic Pb exposure during development influences hippocampal PKC activity and distribution. These changes may be involved in the subclinical neurotoxicity of chronic Pb exposure in young children.

Preparatory Activities for 1995 World Summit on Social Development

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Geographical Patterns of Cultural Values, Entrepreneurship and Economic Development

Globalization and information technologies are new realities that have brought profound changes in lifestyles worldwide. This is reshaping the overall pattern of life custom, cultural production, consumption and trade in a world increasingly filled with changes and economic diversity. In an age of globalization, often ask questions and discussions concerning about successes and vitalities of nations. Globalization and technological revolutions race ahead and transform the world, and how to traces the real business to success. There are thousands of good examples where any nations have shown entrepreneurial talents and have succeeded. It is culture that principally explains, in many cases, or geographical pattern where some countries are developing more rapidly and more successfully than others. How to explain economic success of this nation＇s miracles or simple the secret is creative entrepreneurships？ This paper explores the complex interactions between the geographic pattern from one side and cultural, technological and social aspects of entrepreneurship from other side which generates the dynamic processes of the world economy. In this era of transformation, creativity and knowledge entrepreneurship are powerful tools of fostering economic progress and development.

To Actively Perform the Judicial Administration Function and Promote the Development of Cause of Human Rights

Respect for human rights and protection of human rights are significant rules in the Constitution of the People’s Republic of China.In 2015,judicial administration departments at all levels legally exercised their duties,implemented the principles and rules in constitution,and kept strengthening propagation of human rights through creation of contents and methods which had acquired great effects.What they have done contributes significantly toward the development of human rights in China.

Empirical Research on the Influence of Export Market Diversification on Total Factor Productivity: Based on the Perspective of Trade Protection

This paper mainly explores the impact of export market diversification as an important measure to deal with trade friction on firms total factor productivity.Firstly,this article focuses on the theoretical analysis of the impact mechanism,including risk diversification,reversal effect and spillover effect.Based on the sample data of Chinese manufacturing export enterprises from 2000 to 2007,this paper conducts an empirical test on the relationship between export market diversification and total factor productivity.The result indicates that export market diversification has a significant positive effect on the total factor productivity of enterprises.After considering the endogenous problem,by controlling the fixed effects,using the two-stage least square method and changing the duration of the sample for robustness analysis,the results are still consistent.In addition,the role of diversification policy in total factor productivity presents heterogeneous characteristics in terms of different types of enterprise ownership,export intensity,industry competition,trade methods,and the development degree of exporting market.Accordingly,this paper puts forward corresponding policy recommendations.

Cloning, expression profiling and promoter functional analysis of bone morphogenetic protein 2 in the tongue sole(Cynoglossus semilaevis)

BMP2 plays crucial roles in vertebrate developmental process and acts as a bone inducer during osteogenesis. We present here the molecular cloning of bmp2 cDNA from the marine flatfish Cynoglossus semilaevis, and the analysis of bmp2 expression profiling and promoter function. The full length of bmp2 cDNA sequence is 2 048 bp,which encodes a protein of 422 amino acids. Tissue expression distribution of bmp2 was examined in 14 tissues of mature individuals by quantitative real time PCR（qRT-PCR）. The results revealed that bmp2 was expressed ubiquitously, and the highest expression level was detected in the spinal cord. Moreover, bmp2 expression levels were detected at 15 sampling time points of early developmental stages（egg, larva, juvenile and fingerling stages）.The highest expression level of bmp2 was observed at the gastrula stage, which was about ten times higher than those at the other three embryo stages. Whole-mount in situ hybridization showed that the bmp2 signal was strongly detected at the location of the crown-like larval fin, heart and liver, and slightly expressed in the notochord at one day post hatch（dph）; then the expression of bmp2 started to be concentrated in notochord at three dph. Subsequently, we characterized the 5′-flanking region of bmp2 by testing the promoter activity by Luciferase reporter assays. Positive regulatory region was detected at the location of –179 to ＋109. The predicted transcription factor binding sites（E-box binding factors, zinc finger transcription factor, etc.） in this region might participate in the transcriptional regulation of the bmp2 gene.

The development and function of dendritic ce ）opulations and their regulation by miRNAs

Dendritic cells （DCs） are important immune cells linking innate and adaptive immune responses. DCs encounter various self and non-self antigens present in the envi- ronment and induce different types of antigen specific adaptive immune responses. DCs can be classified into lymphoid tissue-resident DCs, migratory DCs, non-lym-phoid resident DCs, and monocyte derived DCs （moDCs）. Recent work has also established that DCs consist of developmentally and functionally distinct subsets that differentially regulate T lymphocyte func- tion. The development of different DC subsets has been found to be regulated by a network of different cytokines and transcriptional factors. Moreover, the response of DC is tightly regulated to maintain the homeostasis of immune system. MicroRNAs （miRNAs）are an important class of cellular regulators that modulate gene expres- sion and thereby influence cell fate and function. In the immune system, miRNAs act at checkpoints during hematopoietic development and cell subset differentia- tion, they modulate effector cell function, and are implicated in the maintenance of homeostasis. DCs are also regulated by miRNAs. In the past decade, much progress has been made to understand the role of miRNAs in regulating the development and function of DCs. In this review, we summarize the origin and dis- tribution of different mouse DC subsets in both lym- phoid and non-lymphoid tissues. The DC subsets identified in human are also described. Recent progress on the function of miRNAs in the development and activation of DCs and their functional relevance to autoimmune diseases are discussed.

Alloying cobalt with ruthenium in nitrogen doped graphene layers for developing highly active hydrogen evolution electrocatalysts in alkaline media

Subject Code:B01With the support by the National Natural Science Foundation of China,a creative study by the research group led by Prof.Chen Qianwang(陈乾旺)from the University of Science and Technology of China and High Magnetic Field Laboratory,Hefei Institutes of Physical Science,Chinese Academy of