Analysis on the Development Trend and Countermeasures of Clopidogrel Bisulfate

Objective To analyze the development trend of clopidogrel bisulfate so as to provide suggestions for the research and development(R&D)of China’s pharmaceutical enterprises.Methods By studying the development process of thiophenic pyridine drugs,we found that clopidogrel bisulfate belongs to the second generation product.Then,the patent status of generic drugs of thiophene in the United States and China was analyzed to identify the key points and trends of its R&D.Results and Conclusion This paper analyzes the patent and important technology of clopidogrel to predict its development trend,and put forward countermeasures for Chinese pharmaceutical enterprises.

Panel Discussion on“Development Trends of Computer Science in the New Era”

At the panel session of the 3rd Global Forum on the Development of Computer Science,attendees had an opportunity to deliberate recent issues affecting computer science departments as a result of the recent growth in the field.6 heads of university computer science departments participated in the discussions,including the moderator,Professor Andrew Yao.The first issue was how universities are managing the growing number of applicants in addition to swelling class sizes.Several approaches were suggested,including increasing faculty hiring,implementing scalable teaching tools,and working closer with other departments through degree programs that integrate computer science with other fields.The second issue was about the position and role of computer science within broader science.Participants generally agreed that all fields are increasingly relying on computer science techniques,and that effectively disseminating these techniques to others is a key to unlocking broader scientific progress.

The Development Trend of Enterprise Business Administration and the Innovation of Management Mode

In the context of the new period,the continuous growth of social and economic levels and the rapid update of information technology have significantly impacted the business management of Chinese enterprises,presenting substantial challenges.The intensification of market competition exerts development pressure on many enterprises,and coupled with the unstable strength of some businesses,numerous problems in business management arise.These issues hinder the smooth execution of various business activities.Therefore,it is crucial to ensure effective business administration to conduct different business activities in an orderly manner,promptly avoid adverse risks,and strengthen control over multiple factors.The innovation and improvement of business administration are of great significance for enhancing the management level and market competitiveness of modern enterprises,accelerating their healthy development,and creating numerous opportunities.Consequently,this paper analyzes and explores the development trends of enterprise business administration and the innovation of management models for reference.

Research on the Comprehensive Development Trend of National Fitness Activity Centers

With the further advancement of the“National Fitness”strategy and the continuous development of the information age,the National Fitness Activity Centers have become more comprehensive.The comprehensiveness is reflected in the design of diversified sports functions and spaces.The article serves to explore the comprehensive development trend of National Fitness Activity Centers.Through summarizing and sorting out domestic and foreign cases,the trend of the comprehensive development of National Fitness Activity Centers is predicted at three levels:industry,city,and individual functions.

Evolution and Development Trend Prospect of Metal Milling Equipment

The world is currently undergoing profound changes which have never happened within the past century.Global competition in the technology and industry fields is becoming increasingly fierce.The strategic competition of the major powers further focuses on the manufacturing industry.Developed countries such as the United States,Germany,and Japan have successively put forward strategic plans such as“re-industrialization”and“return of manufacturing industry”,aiming to seize the commanding heights of a new round of global high-end technology competition and expand international market share.Standing at the historic intersection of a new round of scientific and technological revolution and China's accelerated high-quality development,the“14th Five-Year Plan”clearly pointed out that intelligent manufacturing is the main development trend to promote China's manufacturing to the medium-high end of the global value chain.This reflects the importance of advanced manufacturing for national strategic layout.To better grasp the development direction of advanced manufacturing equipment,the development process and current application status of manufacturing equipment are summarized,and thereafter the characteristics of manufacturing equipment in different development stages of the manufacturing industry are analyzed.Finally,the development trend of advanced milling equipment is prospected.

Review and Development Trends of Dynamic Adaptive Building Skin Research Based on CiteSpace Analysis

Building skin plays an important role in reducing energy consumption,and low-carbon ecology has become the development goal of architecture all over the world.Through the dynamic control of variable components on the surface,the building with dynamic adaptive building skin can better adapt to the climate,thus achieving better energy saving effects.By searching the articles in the web of science database and using CiteSpace software for visualization analysis,this paper analyzes the research process,research hotspot and research trend of dynamic adaptive building skin from the perspectives of time,quantity,distribution domain,representative experts and articles,institutions,keywords,co-citations and main research contents.It is concluded that the development trend of dynamic adaptive building skin includes the application of efficiency simulation,new materials,bionic technology,and the combination of solar photovoltaics.

Current situation and development trend of design methods for subgrade structure of high speed railways

Purpose–This method will become a new development trend in subgrade structure design for high speed railways.Design/methodology/approach–This paper summarizes the structural types and design methods of subgrade bed for high speed railways in China,Japan,France,Germany,the United States and other countries based on the study and analysis of existing literature and combined with the research results and practices of high speed railway subgrade engineering at home and abroad.Findings–It is found that in foreign countries,the layered reinforced structure is generally adopted for the subgrade bed of high speed railways,and the unified double-layer or multi-layer structure is adopted for the surface layer of subgrade bed,while the simple structure is adopted in China;in foreign countries,different inspection parameters are adopted to evaluate the compaction state of fillers according to their respective understanding and practice,while in China,compaction coefficient,subsoil coefficient and dynamic deformation modulus are adopted for such evaluation;in foreign countries,the subgrade top deformation control method,the subgrade bottom deformation control method,the subsurface fill strength control method are mainly adopted in subgrade bed structure design of high speed railways,while in China,dynamic deformation control of subgrade surface and dynamic strain control of subgrade bed bottom layer is adopted in the design.However,the cumulative deformation of subgrade caused by train cyclic vibration load is not considered in the existing design methods.Originality/value–This paper introduces a new subgrade structure design method based on whole-process dynamics analysis that meets subgrade functional requirements and is established on the basis of the existing research at home and abroad on prediction methods for cumulative deformation of subgrade soil.

TRENDS AND COUNTERMEASURES FOR THE DEVELOPMENT OF COMPUTER TECHNOLOGY AND INDUSTRY IN THE 1990S

This article describes the trends and countermeasures for the development of computer technology and industry in the 1990s on the basis of changes in two large structures ( i.e. industry structure and product structure), and four guiding technologies (i.e. massively parallel processing technology, high-speed network technology, multimedia technology, and artificial intelligence).

Study on the technologies development trend of high speed EMUs

High speed railway technologies are rapidly development in the world.The total distance of the high speed railway is more than 40,000 kilometers in China,and many types of high speed Electrical Multi-Units(EMUs)are operated.The top operation velocity of the train reaches 350 km/h.New science and technologies are developing rapidly.New generation technologies such as the information technology,intelligent manufacturing,new material and processing,innovating design philosophy have revolutionary influence on the high speed train.It promotes the high speed train performance such as intelligence,reliable operation and environment-friendly.Based on many years investigation of the trend of the technology development and requirement of general public,the trend of technology development in five aspects are presented in this paper.The five aspects include economic applicability,high speed and high efficiency,green and low carbon,intelligent safety,comfortable and high quality.

Existing Problems and Countermeasures of Rural Industry Development in Bijie Experimental Area

The development of rural industries in Bijie City of Guizhou Province leads the comprehensive rural revitalization with industrial revitalization,takes high-quality development as the overall guide,focuses on industrial scale,standardization,branding,and marketization,and strives to extend the industrial chain and enhance the value chain to achieve the prosperity of rural industries.In this study,it investigated the current situation of rural industry development in Bijie City(improving the quality and efficiency of characteristic industries,expanding the quantity and efficiency of agricultural products processing industry,recruiting and cultivating large business entities,expanding and strengthening the brand of agricultural products,and upgrading the rural tourism).Through analysis,it found that there are problems such as small scale of production enterprises,insufficient cultivation of independent brands,short industrial chain,low added value,weak market expansion ability,imperfect interest connection mechanism,and insufficient participation of farmers.Finally,it came up with countermeasures for the development of rural industries in Bijie City,including improving supporting facilities and building an extension base;strengthening leading enterprises and focus on deep processing;highlighting regional characteristics and paying close attention to the docking of production and marketing;enhancing the characteristic brand and strengthening the support of science and technology;promoting collaboration and support,and making innovation in the connection of interests.

Research on the Countermeasures for the Development of Biopharmaceutical Industrial Parks in China

Objective To systematically analyze the current development status of biopharmaceutical industrial park in China,sort out the problems and put forward some countermeasures and suggestions.Methods Relevant literature was searched and reviewed to find out the problems faced by the development of biopharmaceutical industrial parks in China.Results and Conclusion Biopharmaceutical industrial parks are developing rapidly due to their unique industrial clustering advantages,but there are problems such as lack of overall planning at the top level,insufficient government support,imperfect talent support services and weak innovation capacity of the parks.It is recommended to promote the rapid development of biopharmaceutical industrial parks and biopharmaceutical enterprises by strengthening top-level design,increasing government support,focusing on talent introduction,and enhancing the innovative strength of the parks.

Research and Development Trend of Shape Control for Cold Rolling Strip

Shape is an important quality index of cold rolling strip. Up to now, many problems in the shape control domain have not been solved satisfactorily, and a review on the research progress in the shape control domain can help to seek new breakthrough directions. In the past 10 years, researches and applications of shape control models, shape control means, shape detection technology, and shape con- trol system have achieved significant progress. In the aspect of shape control models, the researches in the past improve the accuracy, speed and robustness of the models. The intelligentization of shape control models should be strengthened in the future. In the aspect of the shape control means, the researches in the past focus on the roll opti- mization, mill type selection, process optimization, local strip shape control, edge drop control, and so on. In the future, more attention should be paid to the coordination control of both strip shape and other quality indexes, and the refinement of control objective should be strengthened. In the aspects of shape detection technology and shape control system, some new types of shape detection meters and shape control systems are developed and have successfully indus- trial applications. In the future, the standardization of shape detection technology and shape control system should be promoted to solve the problem of compatibility. In general,the four expected development trends of shape control for cold roiling strip in the future are intelligentization, coordi- nation, refinement, and standardization. The proposed research provides new breakthrough directions for improv- ing shape quality.

Status quo and development trend of lost foam casting technology

Lost foam casting(LFC)technology has been widely applied to cast iron and cast steel.However,the development of LFC for Al and Mg alloys was relatively slower than that for cast iron and cast steel.The application of LFC to Al and Mg alloys needs more effort,especially in China.In this paper,the development history of LFC is reviewed,and the application situations of LFC to Al and Mg alloys are mainly discussed.Meanwhile,the key problems of LFC for Al and Mg alloys are also pointed out.Finally,the prospects for LFC technology are discussed,and some special new LFC technologies are introduced for casting Al and Mg alloys.In future,the development trends of green LFC technology mainly focus on the special new LFC methods,metal material,coating,heat treatment,new foam materials as well as purification technology of tail gas,etc.

Problems and countermeasures of sustainable development in Fujian Province in the new century

Fujian province is one of the coastal provinces with rapid economic growth after the reform and opening to the outside world. Being one of the two basic strategies of China in the new era, sustainable development plays a directive role in the coordinated development of socio-economy, natural resources and ecology of Fujian. This paper analyses some important issues influencing sustainable development in Fujian in the next 20 years, such as the sustainable development of economy, investment environment improving and further opening to the outside, urbanization and coordinated development of city system, rational exploitation of natural resources, environmental conservation and ecological rehabilitation, and narrowing intraprovincial gap. Corresponding countermeasures are put forward.

The Status Quo and Development Trend of High-purity Gold Sputtering Targets

This article gives a brief introduction to manufacturers and markets of sputtering targets as well as the manufacturing technology thereof. Then, it analyzes the application of high-purity gold sputtering targets in the fields of integrated circuit, information storage, flat panel display, etc. Based on the above, the article analyzes the processing development trend for the high-purity gold sputtering targets in aspects of ultra-high purity, manufacturing technology, analysis and testing technologies.

Advances and development trends in eco-friendly pavements

The major contemporary in road pavement engineering is related to the creation of green and sustainable infrastructures,e.g.,reduction of environmental impacts,increase in traffic safety,and transportation efficiency,etc.This review presents the recent trends in research and the technical solutions developed so far to address these challenges.After the analysis of research status in the past decades,a novel technology system of eco-friendly pavements is proposed considering two solutions,materials modification and structure improvement.The construction of an eco-friendly pavement can be achieved thanks to several different technologies ensuring permeable,noise-reducing,self-luminous,and exhaust-decomposing properties as well as apporting lower heat absorbing and enhanced anti-/de-icing characteristics.A systematic review of these technologies is presented pivoting on four main aspects:technical principle,material and structural composition,performance evaluation,and engineering application.The current trend in road engineering is combining the pavement infrastructure with various eco-friendly functions,e.g.,water permeability,noise reduction,low heat absorption,exhaust gas decomposition,and anti-/de-icing.Finally,the review lists the drawbacks of the existing technologies,including high cost,single function,etc.,and depicts the future developing direction and architecture of the next generation of eco-friendly pavements in which the road infrastructure should have more environmentally friendly functions than the existing technology.

Foreign Cooperation and Development Trends of the Russian Petroleum Industry and Prospects of Sino-Russian Cooperation in Oil and Gas

This article is focused on the analysis of the international cooperation of the Russian petroleum industry and its development trend. Also discussed here are the patterns that the foreign oil companies used in acquiring Russian petroleum assets, and the cooperation models of petroleum exploration and production in Russia. The Russian government encourages foreign oil companies to establish strategic alliances with domestic companies that keep good relations with the government. To achieve this goal, the government provides foreign companies with the space for cooperation in such aspects as advanced technology and management culture. International cooperation in petroleum industry will be further developed under the macro-control of the Russia State energy strategy. The energy cooperation between China and Russia will enter a new phase full of hopes and challenges after the past unfavorable situation is gradually overcome.

Current Status and Development Trend of Natural Gas Industry in China

In China, the proven reserves of natural gas is 3.86 trillion cubic meters (tcm). This figure will quite possibly increase at a high speed in the future. At present, the annual production of natural gas has exceeded 34 billion cubic meters (bcm), which, likewise, will rise sharply. The pipeline construction has basically taken shape, which will be gradually perfected. And the gas consumption market is in the startup stage, which will be rapidly expanded in the quite near future.

A study on the development trends of tourist marketing policies in the 21^(ST) century

From the view point of tourist marketing, tourist features of popularity and mass, brand and sense, quality and comfort, level and difference, prevalence and society are studied, and the development trends of tourist marketing policies in the 21st century are put forward in this paper. Such as combining sustainable strategies in tourist development with ecology in green marketing, combining information of tourist trends with network in knowledge marketing, combining innovation in tourist products with diversification in marketing objects, combining levels in marketing goals with integer in marketing decision, combining solid in marketing measures with flexibility in marketing policies, combining conformity in marketing channels with double directions in marketing communication and combining the systems of marketing service with culture in marketing activities.

Problems and countermeasures for land exploitation and utilization in China's development areas

s: The planning area and developing area in China's l29 national and 584 provincial development areas cover 8000 km2 and l500 km2 respectively. By typical field investigations we found that China's development areas have the characteristics of abundant categories, excessive quantities, large scales and dense localities in coastlands, border areas and river banks. And their utilization have 4 features of mainly collecting and occupying agricultural lands, minor rebuilding of old city; mainly taking up cultivated lands, minor exploiting and utilizing barren mountains and bleak sloping lands; collecting and occupying lands at first, utilizing afterwards; using large quantities of lands but obtaining comparatively fewer benefits. According to the analyses, China's development areas can be concluded into one of the four categories: constructed from cultivated lands, reconstructed from old cities, constructed from coastlands and islands, and constructed from barren mountains and desolate sloping lands. Their corresponding problems of unsuitable planning and distribution leaving cultivated lands unused, low remission price and chaotic management measures are analyzed in detail and the countermeasures are put forward. These include planning and distribution the lands in an integrated way, managing all these lands in a unified system. improving the growth pattern of their economy, and advancing their utilization and output ratios.