Digital psychiatry in low-and-middle-income countries:New developments and the way forward

Low-and middle-income countries(LMICs)bear the greater share of the global mental health burden but are ill-equipped to deal with it because of severe resource constraints leading to a large treatment gap.The remote provision of mental health services by digital means can effectively augment conventional services in LMICs to reduce the treatment gap.Digital psychiatry in LMICs has always lagged behind high-income countries,but there have been encouraging developments in the last decade.There is increasing research on the efficacy of digital psychiatric interventions.However,the evidence is not adequate to conclude that digital psychiatric interventions are invariably effective in LMICs.A striking development has been the rise in mobile and smartphone ownership in LMICs,which has driven the increasing use of mobile technologies to deliver mental health services.An innovative use of mobile technologies has been to optimize task-shifting,which involves delivering mental healthcare services in community settings using non-specialist health professionals.Emerging evidence from LMICs shows that it is possible to use digital tools to train non-specialist workers effectively and ensure that the psychosocial interventions they deliver are efficacious.Despite these promising developments,many barriers such as service costs,underdeveloped infrastructure,lack of trained professionals,and significant disparities in access to digital services impede the progress of digital psychiatry in LMICs.To overcome these barriers,digital psychiatric services in LMICs should address contextual factors influencing the delivery of digital services,ensure collaboration between different stakeholders,and focus on reducing the digital divide.

Conventional Geothermal Systems and Unconventional Geothermal Developments: An Overview

This paper provides an overview of conventional geothermal systems and unconventional geothermal developments as a common reference is needed for discussions between energy professionals. Conventional geothermal systems have the heat, permeability and fluid, requiring only drilling down to °C, normal heat flow or decaying radiogenic granite as heat sources, and used in district heating. Medium-temperature (MT) 100°C - 190°C, and high-temperature (HT) 190°C - 374°C resources are mostly at plate boundaries, with volcanic intrusive heat source, used mostly for electricity generation. Single well capacities are °C - 500°C) and a range of depths (1 m to 20 Km), but lack permeability or fluid, thus requiring stimulations for heat extraction by conduction. HVAC is 1 - 2 m deep and shallow geothermal down to 500 m in wells, both capturing °C, with °C are either advanced by geothermal developers at <7 Km depth (Enhanced Geothermal Systems (EGS), drilling below brittle-ductile transition zones and under geothermal fields), or by the Oil & Gas industry (Advanced Geothermal Systems, heat recovery from hydrocarbon wells or reservoirs, Superhot Rock Geothermal, and millimeter-wave drilling down to 20 Km). Their primary aim is electricity generation, relying on closed-loops, but EGS uses fractures for heat exchange with earthquake risks during fracking. Unconventional approaches could be everywhere, with shallow geothermal already functional. The deeper and hotter unconventional alternatives are still experimental, overcoming costs and technological challenges to become fully commercial. Meanwhile, the conventional geothermal resources remain the most proven opportunities for investments and development.

A review on lightweight materials for defence applications:Present and future developments

The defence sector is now at an advanced level,catering to the global scenario,and countries also invest heavily in research and development.Countries around the world have spent a lot of money on research and development over the years in order to stay ahead of their competitors.Lightweight materials are critical in defence applications because they allow components to be lighter without sacrificing strength.This review provides an overview of the research related to defence applications.The book provides comprehensive details on current trends in the application of lightweight materials in defence.This review also includes historical and current perspectives on defence technologies.It discusses uses of lightweight materials such as metal matrix composites,polymer composites,ceramic matrix composites,fiber composites in defence sectors Finally,the review paper also emphasizes future military applications of lightweight materials.

Resistance to targeted therapy in metastatic colorectal cancer:Current status and new developments

Colorectal cancer(CRC)is one of the most lethal and common malignancies in the world.Chemotherapy has been the conventional treatment for metastatic CRC(mCRC)patients.However,the effects of chemotherapy have been unsatisfactory.With the advent of targeted therapy,the survival of patients with CRC have been prolonged.Over the past 20 years,targeted therapy for CRC has achieved substantial progress.However,targeted therapy has the same challenge of drug resistance as chemotherapy.Consequently,exploring the resistance mechanism and finding strategies to address the resistance to targeted therapy,along with searching for novel effective regimens,is a constant challenge in the mCRC treatment,and it is also a hot research topic.In this review,we focus on the current status on resistance to existing targeted therapies in mCRC and discuss future developments.

Recent developments and applications on high-performance cast magnesium rare-earth alloys

During the past decades,with the increasing demands in lightweight structural materials,Mg alloys with low density and high performance have been extensively investigated and partly applied in some industries.Especially when rare earth(RE)elements are added as major alloying elements to Mg alloys,the alloy strength and creep resistance are greatly improved,which have promoted several series of Mg-RE alloys.This paper reviews the progress and developments of high-performance Mg-RE alloys in recent years with emphasis on cast alloys.The main contents include the alloy design,melt purification,grain refinement,castability,novel liquid casting and semisolid forming approaches,and the industrial applications or trials made of Mg-RE alloys.The review will provide insights for future developments of new alloys,techniques and applications of Mg alloys.

RELATIONSHIP BETWEEN DEVELOPMENTS OF THE HUANGHE AND YONGDING RIVERS AND THE EVOLUTION OF THE FOSSIL LAKES OF THE CENOZOIC ERA IN THE DRAINAGE AREA

The Huanghe and Yongding rivers were formed before the early and middle Pliocene epoch. Then they became interior rivers because of the appearance of interior fault lake basins at the end of the Pliocene epoch. The interior flow period continued until the end of the early Pleistocene or the middle pf the Middle Pleistocene, and then they changed into the exterior rivers again till today.

Construction of China Osmanthus City and Intellectual Property Right Protection in Xianning City in the Context of Three New Developments

Xianning City of Hubei Province is one of the five major traditional osmanthus producing areas in the world and the hometown of osmanthus in China. Xianning is constructing China Osmanthus City in the whole city. This paper first introduces the main characteristics of the osmanthus industry in Xianning City, and analyzes the characteristics of traditional knowledge, biological genetic resources, new plant varieties, patents, geographical indications, and trademarks. Then, it studies the intellectual property resources of the osmanthus industry, and analyzes the main problems existing in the construction of China Osmanthus City and intellectual property right protection. Finally, it comes up with constructive recommendations including applying for China and Globally Important Agricultural Heritage Systems, developing colored-leaf osmanthus varieties, creating a regional public brand of osmanthus specialty products, and building a new development pattern of osmanthus industry.

New Developments in the Calorimetry of High-Temperature Materials

1. Introduction Thermodynamics forms the fundamental underpinning of reactivity, transformation, and stability, and controls processes such as synthesis, corrosion and degradation, environmental transport, catalysis, and biological reactivity. In the materials field, the wealth of new compounds, polymorphs, hybrid organic–inorganic hybrid materials and metal organic frameworks, high-entropy alloys, and multiphase and nanophase materials attained by a variety of non-equilibrium synthesis and processing methodologies has outrun the available thermodynamic data, hampering current understanding of synthetic pathways, materials compatibility, and longevity during use, degradation, corrosion, and dissolution, and limiting our understanding of environmental contamination and transport for new materials.

Arginine: New and Exciting Developments for an“Old”Amino Acid

Arginine (2-amino-5-guanidino pentanoic acid) was shown in 1895 by Hedin to be present in the proteins of horn. Metabolic nitrogen balance studies, conducted in 1957 by Rose in human adults and in 1959 by Snyderman and coworkers in young infants, revealed that a dietary source of this amino acid was not an obligatory requirement for growth and maintenance of nitrogen homeostasis in healthy individuals. Hence, It was initially classified as a non-essential (dispensable) amino acid and, perhaps, for reasons of this classification arginine did not receivc the earlier atteniion it now deserves, in relation to an understanding of the nutritional biochemistry and physiology of its metabolism in humans subjects. However, there is currently a considerable interest in the cellular and tissue functions, as well as clinical, therapeutic significance, of arginine. In this paper we review the multiple functions of arginlne, including its role in the L-arginine-nitric oxide pathway,cellular regeneration, immune function, protein synthesis and protein breakdown. We then consider some in vivo aspects of the physiology of arginine metabolism, which varies greatly among eukaryotes, with particular reference to humans. Against this background, studies of arginine in the nutrition of humans under various pathophysiological conditions are reviewed briefly. Finally, a new, updated concept for the metabolic basis for the 'conditional essentiality' of arginine is proposed

New Developments on Existence and Uniqueness of Solutions to Some Models in Atmospheric Dynamics

This survey is concerned with the new developments on existence and uniqueness of solutions of some basic models in atmospheric dynamics, such as two-and three-dimensional quasi-geostrophic models and three-dimensional balanced model. The main aim of this paper is to introduce some results about the global and local (with respect to time) existence of solutions given by the authors in recent years, but others' important contributions and the literature on this subject are also quoted. We discuss briefly the relationships among the existence and uniqueness, physical instability and computational instability. In the appendixes, some key mathematical techniques in obtaining our results are presented, which are of vital importance to other problems in geophysical fluid dynamics as well.

Molten Salts and Applications Ⅲ: Worldwide Molten Salt Technology Developments in Energy Production and Storage

Supported by Office of Naval Research (ONR), this paper presents a survey of molten salt technology used in solar power storage. Excess energy from solar power stations and other baseline power production methods can be stored in molten salts (MS) in the 565°C range, therefore allowing the use of large containers to store energy for up to a week and generate eight hours of electricity or more to be used during peak demand hours, at night, or adverse weather conditions, depending on the container size. The technology could also be used to conserve the spin off energy in the grids from nuclear or coal power production. Real life examples of concentrating solar power (CSP) plants, both domestically and worldwide, are presented with details about the type of solar collection, capacity, and energy production. Commercial solar power stations have been constructed in the United States and overseas, particularly in Spain, with molten salt being considered for use in these facilities. Some facilities use a field of flat mirrors and collection towers while others use parabolic troughs.

RECENT DEVELOPMENTS OF DIRECT BONDED COPPER(DBC)SUBSTRATES FOR POWER MODULES

DBC substrates are the standard circuit boardsfor power modules. Using the DBC technologythick copper foils (0.125mm - 0.Tmm) arecladded to Alumina or Aluminum Nitride,The strong adhesion of the copper to ceramicbond reduces the thermal expansion coefficientin horizontal direction only slightly above theTEC of the ceramic itself. This allows directsilicon attach of large dies without using TECcontrolling layers.As DBC technology is using copper foils,integralleads overhanging the ceramic can be realized...

Improvement in potassium ion batteries electrodes: Recent developments and efficient approaches

Demand for efficient and continuous application for high-grid energy storage systems involves the study towards novel battery technologies. Hence, considering the vast naturally available resources of potassium all over the world and its encouraging intercalation chemistries, it has recently enticed attention in electrochemical energy storage industry in the form of potassium ion batteries (PIBs). The major factor in this K+ based battery, is to develop efficient approaches to manufacture electrode substance to intercalate its big size potassium ions with considerable voltage, kinetics, charge/discharge capacity, capacity retention, cost, etc. This study contributes in the recent developments of anode and cathode materials for PIBs, including several electrode materials in regards to synthesis, structure, electrochemical performance, and K-storage mechanisms. Finally, the review contributes to provide helpful sources for the increasing number of scientists working in this industry regarding its critical issues and challenges and also to indicate the future direction of electrode materials in PIBs.

Progress in Physics and Technology Developments for the Modification of JT-60

Recent progress in the physics and engineering design study for themodification programme of JT-60 is presented. In order to achieve a steady state high-βplasmaoperation, which is the dominant issue of this programme, physics design for the MHD control and thestability analysis is investigated. Engineering design and the R & D for the superconducting coils,irradiation shield are performed well towards the mission of programme.

Key Developments in Indian Irrigation Sector

The key developments in Indian Irrigation sector have been presented by briefly discussing the following topics:1.Present Indian Irrigation Challenges and Way Forward.2.Regulatory Interventions in Water Sector in India(Maharashtra’s Example).3.Roles and Activities of Maharashtra Water Resource Regulatory Authority(MWRRA).4.Major Achievements of MWRRA.5.Indian National Committee On Irrigation and Drainage(INCID).6.Irrigation,Command Area Development and Micro Irrigation in India.7.Flood Management and Its Measures.8.Capacity Building.

Recent developments in stainless steels:austenitic,ferritic,duplex

A review is given concerning some of the recent industrial developments of stainless steels. In austenitic stainless steels,two different directions of alloy development are noticeable:low nickel austenitic stainless steels and high nitrogen stainless steels.In these two cases the aims are different,particularly in terms of strength,but the philosophy of alloy development and the scientific approaches are very similar and they all revolve about the role of nitrogen as an alloying element and how this affects strength,ductility and corrosion resistance. There is now a broad and useful basis of information as to how nitrogen affects solid solution hardening,grain boundary hardening and work hardening and how to make use of these effects in developing materials required by the world market. In the field of corrosion resistance,ferritic,duplex and austenitic stainless steels compete with each other and now there is a growing body of information concerning the relative corrosion resistance based on laboratory data. However,for practical applications and for alloy selection,more than just laboratory data are needed,and thus,the first results are presented here of a many years comparison of the corrosion resistance of 24 commercial stainless steels exposed to corrosion in outdoors marine atmosphere.Hope is expressed to involve in the near future even more steels from a wider range of manufacturers in such corrosion studies.This might help consumers in appropriate alloy selection.It might also help steel makers in developing appropriate stainless steel grades.

Latest Developments and Problems in Standardization of Resource Control Technologies for NGN

As a hot spot of next generation network, research over resource control has been carried out for years both in China and abroad. With a gradual progress in standardization, this field presents new development trends and features. Based on latest progresses in standardization promoted by ITU-T, TISPAN and 3GPP, new technologies concerned with resource control are introduced. Considering the problems faced in standardization deployment, relevant resource control functions are also analyzed in this article.

Developments in the Pharmaceuticals Industry

China’s pharmaceuticals industry is one of the industries making use of foreign funds and running three kinds of foreign-funded enterprises from an early date. In 1980, it signed a contract with the Japanese Pharmaceu-tical Enterprise to establish the China Otsuka Pharmaceuticals Co. Ltd.---the first joint venture in China’s pharma-ceuticals industry. According to incom-

Developments in China's Daily-Use Glass Industry

The main products of China’s dailyuse glass industry include bottle glass, utensil glass, technical glass (glass instruments, syringes, thermometers and industrial glass) and insulated container glass. These four categories of products are not only people’s daily necessities but also bottles for packing use,

New Developments of Tungsten Technology in China

I.IntroductionIt is well known that China is rich in natural resources of tungsten.Before 1949 there was al-most no tungsten industry in our country except mining and ore dressing.Tremendous changeshave taken place after 1949.We have built our metallurgical industry of tungsten.Especially start-ing from the last decade much progress has been made not only in production technologies and