Uncertainties in the International Situation Are on the Increase and Transformation of International Pattern and Order Accelerates and Deepens Since 2016,the world has begun to enter into a historical period of uncert...Uncertainties in the International Situation Are on the Increase and Transformation of International Pattern and Order Accelerates and Deepens Since 2016,the world has begun to enter into a historical period of uncertainty.The fact that the Ukrainian Crisis has dragged on for long and that展开更多
Drug development in oncology is undergoing a substantial shift nowadays. The drivers for this are multi-factorial. On the one side, drug development is performed more rationally than ever, profiting from the scientifi...Drug development in oncology is undergoing a substantial shift nowadays. The drivers for this are multi-factorial. On the one side, drug development is performed more rationally than ever, profiting from the scientific advances in molecular biology in general and the elucidation of the various "omes" from genome to metabolome in particular.展开更多
The characteristics of the urban heat island effect and the climate change in Shanghai and its possible mechanism are analyzed based on monthly meteorological data from 1961 to 1997 at 16 stations in Shanghai and its ...The characteristics of the urban heat island effect and the climate change in Shanghai and its possible mechanism are analyzed based on monthly meteorological data from 1961 to 1997 at 16 stations in Shanghai and its adjacent areas. The results indicate that Shanghai City has the characteristics of a heat island of air temperature and maximum and minimum air temperature, a cold island of surface soil temperature, a weak rainy island of precipitation, and a turbid island of minimum visibility and aerosols, with centers at or near Longhua station (the urban station of Shanghai). Besides theses, the characteristics of a cloudy island and sunshine duration island are also obvious, but their centers are located in the southern part of the urban area and in the southern suburbs. A linear trend analysis suggests that all of the above urban effects intensified from 1961 to 1997. So far as the heat island effect is concerned, the heat island index (difference of annual temperature between Longhua and Songjiang stations) strengthens (weakens) as the economic development increases (decreases). The authors suggest that the heating increase caused by increasing energy consumption due to economic development is a main factor in controlling the climate change of Shanghai besides natural factors. On the other hand, increasing pollution aerosols contribute to the enhancement of the turbid island and cooling. On the whole, the heating effect caused by increasing energy consumption is stronger than the cooling effect caused by the turbid island and pollution aerosols.展开更多
The study was made by observing the annual change of the gonadal development of amphioxus in Xiamen cohtinuously for two years from November, 1986 to November, 1988. We determined the gonadal diameter, gonadosomatic i...The study was made by observing the annual change of the gonadal development of amphioxus in Xiamen cohtinuously for two years from November, 1986 to November, 1988. We determined the gonadal diameter, gonadosomatic index of each amphioxus, and observed the histological characteristic of the gonadal development of the female and male by cut section, which provided the basis for dividing the stages gonads and the determining level of the gonadal development of amphioxus in each month.展开更多
The process of development and calibration for the first Moon-based ex- treme ultraviolet (EUV) camera to observe Earth's plasmasphere is introduced and the design, test and calibration results are presented. The E...The process of development and calibration for the first Moon-based ex- treme ultraviolet (EUV) camera to observe Earth's plasmasphere is introduced and the design, test and calibration results are presented. The EUV camera is composed of a multilayer film mirror, a thin film filter, a photon-counting imaging detector, a mech- anism that can adjust the direction in two dimensions, a protective cover, an electronic unit and a thermal control unit. The center wavelength of the EUV camera is 30.2 nm with a bandwidth of 4.6nm. The field of view is 14.7° with an angular resolution of 0.08°, and the sensitivity of the camera is 0.11 count s-1 Rayleigh-1. The geomet- ric calibration, the absolute photometric calibration and the relative photometric cal- ibration are carried out under different temperatures before launch to obtain a matrix that can correct geometric distortion and a matrix for relative photometric correction, which are used for in-orbit correction of the images to ensure their accuracy.展开更多
With the advent of modern techniques, drugs, and monitoring, general anesthesia has come to be considered an unlikely cause of harm, particularly for healthy patients. While this is largely true, newly emerging clinic...With the advent of modern techniques, drugs, and monitoring, general anesthesia has come to be considered an unlikely cause of harm, particularly for healthy patients. While this is largely true, newly emerging clinical and laboratory studies have sug- gested that exposure to anesthetic agents during early childhood may have long-lasting adverse effects on cognitive function. This concern has been the focus of intense study in the field of anesthesia research. A recent high-profile review by Rappaport et al. (2015) concluded that while many questions remain un- answered, there is strong evidence from laboratory studies that commonly used anesthetics interfere with brain development and that clinical studies suggest a correlation between early childhood exposure to these agents and subsequent effects on learning and cognition. The issue is of sufficient public health importance that a public-private partnership known as Smar- Tots (Strategies for Mitigating Anesthesia-Related Neurotoxicity in Tots) was developed by the FDA to study pediatric anesthetic neurotoxicity. The mechanism of injury underlying this phe- nomenon has yet to be fully elucidated, and there is evidence to suggest that anesthetics may have direct cytotoxic effects on neurons leading to cell death or suppressed neurogenesis (Strat- mann et al., 2010) and that they may interfere with key pro- cesses in neuronal growth and development that underlie brain circuit development (Wagner et al., 2014).展开更多
A large country will undoubtedly show development disparity among its regions: it is not surprising therefore that China would not have developed evenly. In analyzing China’s development features and its manner of en...A large country will undoubtedly show development disparity among its regions: it is not surprising therefore that China would not have developed evenly. In analyzing China’s development features and its manner of enforcing relative policies, the various financial sectors in China cannot be simply regarded as a whole unit: a unified policy would not be suitable for the local conditions of a given area, otherwise it will lost its future direction. This paper measures China’s disparity of financial development during the period展开更多
Although it is generally understood that change is a fundamental component of managing projects in the construction industry in general and an inevitable challenge for large scale infrastructure project in particular,...Although it is generally understood that change is a fundamental component of managing projects in the construction industry in general and an inevitable challenge for large scale infrastructure project in particular, there has been little to no attention in the literature to understand change in this context from a more holistic perspective. For this purpose, this work looks at change through the eyes of a framework of six batteries of change that seem essential to charge an organization's capabilities for change. The framework brings together the expertise of four specialists that all have developed their insights over many years of study and practice, and has been validated through an extensive review of the management literature on organization development and change. Reflections on the application of this model in the construction industry and in large scale infrastructure projects demonstrate that energizing organizations to successfully deal with change goes beyond the traditional techniques of managing change from a program or project management perspective. Assessing the six batteries of change in this context can help organizations to develop capabilities for change that build change energy by balancing formal/rational methods with informal/emotional interventions at both a local(department/subproject) and global(business) level.展开更多
Extensive industrial development is a major challenge to ecological civilization construction. Industrial energy consumption and environmental pollution reduction are desperately needed. The Dongting Lake district, lo...Extensive industrial development is a major challenge to ecological civilization construction. Industrial energy consumption and environmental pollution reduction are desperately needed. The Dongting Lake district, located in Wuhan and the Changsha-Zhuzhou-Xiangtan(CZT)pilot zone, bears the responsibility to ensure national food security and watershed ecological security, and it is an urgent need for the Dongting Lake district to accept the ecological transition of industries. On the analysis of the industrial development status and problems of the Dongting Lake district, some proposals based on the characteristics and reality of the district are pointed out, such as industrial cooperation, proper space layout, ecological innovation, industrial structure upgrading, building of ecological parks, clean production, elimination of backward production capacity, heavy metals governance and so on, as to develop the industrial ecology of the Dongting Lake district.展开更多
The international conference on mountain development in a context of global change with special focus on the Himalayas was held in Kathmandu, Nepal on April 21-26.
文摘Uncertainties in the International Situation Are on the Increase and Transformation of International Pattern and Order Accelerates and Deepens Since 2016,the world has begun to enter into a historical period of uncertainty.The fact that the Ukrainian Crisis has dragged on for long and that
文摘Drug development in oncology is undergoing a substantial shift nowadays. The drivers for this are multi-factorial. On the one side, drug development is performed more rationally than ever, profiting from the scientific advances in molecular biology in general and the elucidation of the various "omes" from genome to metabolome in particular.
基金supported the National Natural Science Foundation of China under Grant No.49899270.
文摘The characteristics of the urban heat island effect and the climate change in Shanghai and its possible mechanism are analyzed based on monthly meteorological data from 1961 to 1997 at 16 stations in Shanghai and its adjacent areas. The results indicate that Shanghai City has the characteristics of a heat island of air temperature and maximum and minimum air temperature, a cold island of surface soil temperature, a weak rainy island of precipitation, and a turbid island of minimum visibility and aerosols, with centers at or near Longhua station (the urban station of Shanghai). Besides theses, the characteristics of a cloudy island and sunshine duration island are also obvious, but their centers are located in the southern part of the urban area and in the southern suburbs. A linear trend analysis suggests that all of the above urban effects intensified from 1961 to 1997. So far as the heat island effect is concerned, the heat island index (difference of annual temperature between Longhua and Songjiang stations) strengthens (weakens) as the economic development increases (decreases). The authors suggest that the heating increase caused by increasing energy consumption due to economic development is a main factor in controlling the climate change of Shanghai besides natural factors. On the other hand, increasing pollution aerosols contribute to the enhancement of the turbid island and cooling. On the whole, the heating effect caused by increasing energy consumption is stronger than the cooling effect caused by the turbid island and pollution aerosols.
文摘The study was made by observing the annual change of the gonadal development of amphioxus in Xiamen cohtinuously for two years from November, 1986 to November, 1988. We determined the gonadal diameter, gonadosomatic index of each amphioxus, and observed the histological characteristic of the gonadal development of the female and male by cut section, which provided the basis for dividing the stages gonads and the determining level of the gonadal development of amphioxus in each month.
文摘The process of development and calibration for the first Moon-based ex- treme ultraviolet (EUV) camera to observe Earth's plasmasphere is introduced and the design, test and calibration results are presented. The EUV camera is composed of a multilayer film mirror, a thin film filter, a photon-counting imaging detector, a mech- anism that can adjust the direction in two dimensions, a protective cover, an electronic unit and a thermal control unit. The center wavelength of the EUV camera is 30.2 nm with a bandwidth of 4.6nm. The field of view is 14.7° with an angular resolution of 0.08°, and the sensitivity of the camera is 0.11 count s-1 Rayleigh-1. The geomet- ric calibration, the absolute photometric calibration and the relative photometric cal- ibration are carried out under different temperatures before launch to obtain a matrix that can correct geometric distortion and a matrix for relative photometric correction, which are used for in-orbit correction of the images to ensure their accuracy.
文摘With the advent of modern techniques, drugs, and monitoring, general anesthesia has come to be considered an unlikely cause of harm, particularly for healthy patients. While this is largely true, newly emerging clinical and laboratory studies have sug- gested that exposure to anesthetic agents during early childhood may have long-lasting adverse effects on cognitive function. This concern has been the focus of intense study in the field of anesthesia research. A recent high-profile review by Rappaport et al. (2015) concluded that while many questions remain un- answered, there is strong evidence from laboratory studies that commonly used anesthetics interfere with brain development and that clinical studies suggest a correlation between early childhood exposure to these agents and subsequent effects on learning and cognition. The issue is of sufficient public health importance that a public-private partnership known as Smar- Tots (Strategies for Mitigating Anesthesia-Related Neurotoxicity in Tots) was developed by the FDA to study pediatric anesthetic neurotoxicity. The mechanism of injury underlying this phe- nomenon has yet to be fully elucidated, and there is evidence to suggest that anesthetics may have direct cytotoxic effects on neurons leading to cell death or suppressed neurogenesis (Strat- mann et al., 2010) and that they may interfere with key pro- cesses in neuronal growth and development that underlie brain circuit development (Wagner et al., 2014).
文摘A large country will undoubtedly show development disparity among its regions: it is not surprising therefore that China would not have developed evenly. In analyzing China’s development features and its manner of enforcing relative policies, the various financial sectors in China cannot be simply regarded as a whole unit: a unified policy would not be suitable for the local conditions of a given area, otherwise it will lost its future direction. This paper measures China’s disparity of financial development during the period
文摘Although it is generally understood that change is a fundamental component of managing projects in the construction industry in general and an inevitable challenge for large scale infrastructure project in particular, there has been little to no attention in the literature to understand change in this context from a more holistic perspective. For this purpose, this work looks at change through the eyes of a framework of six batteries of change that seem essential to charge an organization's capabilities for change. The framework brings together the expertise of four specialists that all have developed their insights over many years of study and practice, and has been validated through an extensive review of the management literature on organization development and change. Reflections on the application of this model in the construction industry and in large scale infrastructure projects demonstrate that energizing organizations to successfully deal with change goes beyond the traditional techniques of managing change from a program or project management perspective. Assessing the six batteries of change in this context can help organizations to develop capabilities for change that build change energy by balancing formal/rational methods with informal/emotional interventions at both a local(department/subproject) and global(business) level.
基金supported by the National Natural Science Foundation of China(7120205571431006)+1 种基金the Major Project of National Social Sciences Fund(15ZDA020)Key Projects of Philosophy and Social Sciences Research of Ministry of Education of China(13JZD016)
文摘Extensive industrial development is a major challenge to ecological civilization construction. Industrial energy consumption and environmental pollution reduction are desperately needed. The Dongting Lake district, located in Wuhan and the Changsha-Zhuzhou-Xiangtan(CZT)pilot zone, bears the responsibility to ensure national food security and watershed ecological security, and it is an urgent need for the Dongting Lake district to accept the ecological transition of industries. On the analysis of the industrial development status and problems of the Dongting Lake district, some proposals based on the characteristics and reality of the district are pointed out, such as industrial cooperation, proper space layout, ecological innovation, industrial structure upgrading, building of ecological parks, clean production, elimination of backward production capacity, heavy metals governance and so on, as to develop the industrial ecology of the Dongting Lake district.
文摘The international conference on mountain development in a context of global change with special focus on the Himalayas was held in Kathmandu, Nepal on April 21-26.