Background: Urinary Incontinence is a common symptom among the older and frail older people. Apart from affecting the quality of life and skin complications, the demand on assistance could be too high for any sufferer...Background: Urinary Incontinence is a common symptom among the older and frail older people. Apart from affecting the quality of life and skin complications, the demand on assistance could be too high for any sufferer. While conservative means of treatment do not work, special incontinence apparel could be a good compromise. Objective: To create an absorbent, antiseptic, antiperspirant and deodourant diaper for the older and dependent people suffering from urinary incontinence. Material and Methods: Antiperspirant and antiseptic medicinal materials have been reported in Traditional Chinese Medicine and two herbs were screened out to provide the required effects. A combination of Fraxini Cortex, Calamine and Zinc oxide made in powder forms was impregnated into a pocket of the diaper. Laboratory tests were performed to confirm the antiseptic, antiperspirant and deodourant effects of the materials. A self-control clinical trial on the diaper was organized in an elderly home. Results: Antibacterial effects against Staphylococcus, E. coli and Candida were proven. Antiperspirant effects were confirmed using acetylcholinesterase inhibitor testings. Volunteers using the Sudoscan machine further demonstrated the weak antiperspirant effects of the herbs. A pilot study on 31 dependent diaper users gave positive feedbacks of more comfort, less leakage, odour and better skin conditions. The overall satisfaction reached 79%. Conclusion: A special diaper with antiseptic, antiperspirant and deodourant effects could be created with inexpensive herbal powder impregnated and could be recommended to the older and frail older people with urinary incontinence.展开更多
Soil Transmitted Helminthes(STH)is always a problem in developing and under developed countries.Children are mostly prone to STH in tropical and non-tropical countries including Pakistan.We have observed ova of Ascari...Soil Transmitted Helminthes(STH)is always a problem in developing and under developed countries.Children are mostly prone to STH in tropical and non-tropical countries including Pakistan.We have observed ova of Ascaris and some non-descriptive objects in the parasitological examination of the fecal material of infant collected from diaper.展开更多
Diaper dermatit is among the widely seen inflamatory skin diseases in neonatals and small 0 - 18 month old children. Control of causative agents as well as providing good genital care may prevent or reduce the risk of...Diaper dermatit is among the widely seen inflamatory skin diseases in neonatals and small 0 - 18 month old children. Control of causative agents as well as providing good genital care may prevent or reduce the risk of the disease. The aim of this study is find out the effect of protective genital care on reducing the diaper dermatit development in 0 - 18 months old inpatient 0 - 18 month old children who are using antibiotic. The study was conducted as prospective half-experimetal using control-experimental groups. Our samples comprise of 0 - 18 month old children admitted at Dokuz Eylul University Practical and Research Hospital, pediatric clinic between January and May 2009, 41 0 - 18 month old children as a control group were not under protective genital care, and 42 0 - 18 month old children as an experimental group were under the protecion and using vaseline. The mothers of the experimental group 0 - 18 month old children were given education. All 0 - 18 month old children were followed-up 3 - 7 days and the collected data were evaluated in computer using Pearson’s chisquare, Fisher’s exact chi-square and Yatest-corrected chi-square tests. The diaper dermatit develop- ment ratio was 34.1% in the control group and 7.1% in the experimental group展开更多
Change is the most fundamental property of a biomarker. In contrast to the blood, which is under homeostatic controls, urine reflects changes in the body earlier and is more sensitive, thus making it a better biomarke...Change is the most fundamental property of a biomarker. In contrast to the blood, which is under homeostatic controls, urine reflects changes in the body earlier and is more sensitive, thus making it a better biomarker source. Moreover, drawing blood from infants and toddlers is difficult and not tolerated well. For patients limited by language, communicating their chief complaint is difficult. Thus, monitoring biomarkers in urine can provide valuable clues for the diagnosis of diseases, especially pediatric diseases. Collecting urine from young children and some adult patients is more challenging than collecting it from healthy adults.Here, we propose a method that uses a fluff pulp diaper to collect urine. Urinary proteins are then eluted and adsorbed onto a piece of nitrocellulose membrane, which can be dried and stored in a vacuum bag. SDS-PAGE and LC-MS/MS analysis indicated that this method is reproducible, and similar proteins were identified as those obtained by an acetone precipitation method. With this simple and economical method, it is possible to collect and preserve urine samples from infants, toddlers, and patients with special needs, even for large-scale biomarker studies.展开更多
文摘Background: Urinary Incontinence is a common symptom among the older and frail older people. Apart from affecting the quality of life and skin complications, the demand on assistance could be too high for any sufferer. While conservative means of treatment do not work, special incontinence apparel could be a good compromise. Objective: To create an absorbent, antiseptic, antiperspirant and deodourant diaper for the older and dependent people suffering from urinary incontinence. Material and Methods: Antiperspirant and antiseptic medicinal materials have been reported in Traditional Chinese Medicine and two herbs were screened out to provide the required effects. A combination of Fraxini Cortex, Calamine and Zinc oxide made in powder forms was impregnated into a pocket of the diaper. Laboratory tests were performed to confirm the antiseptic, antiperspirant and deodourant effects of the materials. A self-control clinical trial on the diaper was organized in an elderly home. Results: Antibacterial effects against Staphylococcus, E. coli and Candida were proven. Antiperspirant effects were confirmed using acetylcholinesterase inhibitor testings. Volunteers using the Sudoscan machine further demonstrated the weak antiperspirant effects of the herbs. A pilot study on 31 dependent diaper users gave positive feedbacks of more comfort, less leakage, odour and better skin conditions. The overall satisfaction reached 79%. Conclusion: A special diaper with antiseptic, antiperspirant and deodourant effects could be created with inexpensive herbal powder impregnated and could be recommended to the older and frail older people with urinary incontinence.
文摘Soil Transmitted Helminthes(STH)is always a problem in developing and under developed countries.Children are mostly prone to STH in tropical and non-tropical countries including Pakistan.We have observed ova of Ascaris and some non-descriptive objects in the parasitological examination of the fecal material of infant collected from diaper.
文摘Diaper dermatit is among the widely seen inflamatory skin diseases in neonatals and small 0 - 18 month old children. Control of causative agents as well as providing good genital care may prevent or reduce the risk of the disease. The aim of this study is find out the effect of protective genital care on reducing the diaper dermatit development in 0 - 18 months old inpatient 0 - 18 month old children who are using antibiotic. The study was conducted as prospective half-experimetal using control-experimental groups. Our samples comprise of 0 - 18 month old children admitted at Dokuz Eylul University Practical and Research Hospital, pediatric clinic between January and May 2009, 41 0 - 18 month old children as a control group were not under protective genital care, and 42 0 - 18 month old children as an experimental group were under the protecion and using vaseline. The mothers of the experimental group 0 - 18 month old children were given education. All 0 - 18 month old children were followed-up 3 - 7 days and the collected data were evaluated in computer using Pearson’s chisquare, Fisher’s exact chi-square and Yatest-corrected chi-square tests. The diaper dermatit develop- ment ratio was 34.1% in the control group and 7.1% in the experimental group
基金supported by the National Key Research and Development Program of China(2016YFC1306300)the National Basic Research Program of China(2013CB530850)the Fundamental Research Funds for the Central Universities(11100704,10300-310421102)
文摘Change is the most fundamental property of a biomarker. In contrast to the blood, which is under homeostatic controls, urine reflects changes in the body earlier and is more sensitive, thus making it a better biomarker source. Moreover, drawing blood from infants and toddlers is difficult and not tolerated well. For patients limited by language, communicating their chief complaint is difficult. Thus, monitoring biomarkers in urine can provide valuable clues for the diagnosis of diseases, especially pediatric diseases. Collecting urine from young children and some adult patients is more challenging than collecting it from healthy adults.Here, we propose a method that uses a fluff pulp diaper to collect urine. Urinary proteins are then eluted and adsorbed onto a piece of nitrocellulose membrane, which can be dried and stored in a vacuum bag. SDS-PAGE and LC-MS/MS analysis indicated that this method is reproducible, and similar proteins were identified as those obtained by an acetone precipitation method. With this simple and economical method, it is possible to collect and preserve urine samples from infants, toddlers, and patients with special needs, even for large-scale biomarker studies.
