Connectivity differences between adult male and female patients with attention deficit hyperactivity disorder according to resting-state functional MRI

Attention deficit hyperactivity disorder（ADHD） is a pervasive psychiatric disorder that affects both children and adults. Adult male and female patients with ADHD are differentially affected, but few studies have explored the differences. The purpose of this study was to quantify differences between adult male and female patients with ADHD based on neuroimaging and connectivity analysis. Resting-state functional magnetic resonance imaging scans were obtained and preprocessed in 82 patients. Group-wise differences between male and female patients were quantified using degree centrality for different brain regions. The medial-, middle-, and inferior-frontal gyrus, superior parietal lobule, precuneus, supramarginal gyrus, superior- and middle-temporal gyrus, middle occipital gyrus, and cuneus were identified as regions with significant group-wise differences. The identified regions were correlated with clinical scores reflecting depression and anxiety and significant correlations were found. Adult ADHD patients exhibit different levels of depression and anxiety depending on sex, and our study provides insight into how changes in brain circuitry might differentially impact male and female ADHD patients.

Different optical properties in different periodic slot cavity geometrical morphologies

In this paper,optical properties of two-dimensional periodic annular slot cavity arrays in hexagonal close-packing on a silica substrate are theoretically characterized by finite difference time domain（FDTD） simulation method.By simulating reflectance spectra,electric field distribution,and charge distribution,we confirm that multiple cylindrical surface plasmon resonances can be excited in annular inclined slot cavities by linearly polarized light,in which the four reflectance dips are attributed to Fabry–Perot cavity resonances in the coaxial cavity.A coaxial waveguide mode TE11 will exist in these annular cavities,and the wavelengths of these reflectance dips are effectively tailored by changing the geometrical pattern of slot cavity and the dielectric materials filled in the cavities.These resonant wavelengths are localized in annular cavities with large electric field enhancement and dissipate gradually due to metal loss.The formation of an absorption peak can be explained from the aspect of phase matching conditions.We observed that the proposed structure can be tuned over the broad spectral range of 600–4000 nm by changing the outer and inner radii of the annular gaps,gap surface topography.Meanwhile,different lengths of the cavity may cause the shift of resonance dips.Also,we study the field enhancement at different vertical locations of the slit.In addition,dielectric materials filling in the annular gaps will result in a shift of the resonance wavelengths,which make the annular cavities good candidates for refractive index sensors.The refractive index sensitivity of annular cavities can also be tuned by the geometry size and the media around the cavity.Annular cavities with novel applications can be implied as surface enhanced Raman spectra substrates,refractive index sensors,nano-lasers,and optical trappers.

Harmonic dissipative soliton resonance pulses in a fiber ring laser at different values of anomalous dispersion

The pulse dynamics of harmonic mode-locking in a dissipative soliton resonance(DSR) region in an erbiumdoped fiber ring laser is investigated at different values of anomalous dispersion. The fiber laser is mode-locked by a nonlinear polarization rotation technique. By inserting 0–200 m anomalous dispersion single-mode fiber in the laser cavity, the cavity length is changed from 17.3 to 217.3 m, and the corresponding dispersion of the cavity ranges from -0.27 to-4.67 ps^2. The observed results show that the tuning range of repetition rate under a harmonic DSR condition is highly influenced by the cavity dispersion. Furthermore, it is found that, by automatically adjusting their harmonic orders, the lasers can work at certain values of repetition rate, which are independent of the cavity length and dispersion. The pulses at the same repetition rate in different laser configurations have similar properties, demonstrating that each achievable repetition rate represents an operation regime of harmonic DSR lasers.