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Resource Allocation for Network Security Risk Assessment:A Non-Cooperative Differential Game Based Approach 被引量:1
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作者 XU Haitao LIN Ruijie 《China Communications》 SCIE CSCD 2016年第4期131-135,共5页
In this paper, we propose a non-cooperative differential game theory based resource allocation approach for the network security risk assessment. For the risk assessment, the resource will be used for risk assess, inc... In this paper, we propose a non-cooperative differential game theory based resource allocation approach for the network security risk assessment. For the risk assessment, the resource will be used for risk assess, including response cost and response negative cost. The whole assessment process is considered as a differential game for optimal resource control. The proposed scheme can be obtained through the Nash Equilibrium. It is proved that the game theory based algorithm is applicable and the optimal resource level can be achieved based on the proposed algorithm. 展开更多
关键词 resource allocation security risk assessment differential game NON-COOPERATIVE Nash Equilibrium
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A risk assessment method considering risk attributes and work safety informational needs and its application
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作者 Cong Luo Yunsheng Zhao Ke Xu 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第4期253-262,共10页
The technological revolution has spawned a new generation of industrial systems,but it has also put forward higher requirements for safety management accuracy,timeliness,and systematicness.Risk assessment needs to evo... The technological revolution has spawned a new generation of industrial systems,but it has also put forward higher requirements for safety management accuracy,timeliness,and systematicness.Risk assessment needs to evolve to address the existing and future challenges by considering the new demands and advancements in safety management.The study aims to propose a systematic and comprehensive risk assessment method to meet the needs of process system safety management.The methodology first incorporates possibility,severity,and dynamicity(PSD)to structure the“51X”evaluation indicator system,including the inherent,management,and disturbance risk factors.Subsequently,the four-tier(risk point-unit-enterprise-region)risk assessment(RA)mathematical model has been established to consider supervision needs.And in conclusion,the application of the PSD-RA method in ammonia refrigeration workshop cases and safety risk monitoring systems is presented to illustrate the feasibility and effectiveness of the proposed PSD-RA method in safety management.The findings show that the PSD-RA method can be well integrated with the needs of safety work informatization,which is also helpful for implementing the enterprise's safety work responsibility and the government's safety supervision responsibility. 展开更多
关键词 risk assessment Safey “51X”evaluation indicator system Four-tier risk assessment model risk attributes process system
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Application of fuzzy analytic hierarchy process and neural network in power transformer risk assessment 被引量:8
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作者 李卫国 俞乾 罗日成 《Journal of Central South University》 SCIE EI CAS 2012年第4期982-987,共6页
In operation,risk arising from power transformer faults is of much uncertainty and complicacy.To timely and objectively control the risks,a transformer risk assessment method based on fuzzy analytic hierarchy process(... In operation,risk arising from power transformer faults is of much uncertainty and complicacy.To timely and objectively control the risks,a transformer risk assessment method based on fuzzy analytic hierarchy process(FAHP) and artificial neural network(ANN) from the perspective of accuracy and quickness is proposed.An analytic hierarchy process model for the transformer risk assessment is built by analysis of the risk factors affecting the transformer risk level and the weight relation of each risk factor in transformer risk calculation is analyzed by application of fuzzy consistency judgment matrix;with utilization of adaptive ability and nonlinear mapping ability of the ANN,the risk factors with large weights are used as input of neutral network,and thus intelligent quantitative assessment of transformer risk is realized.The simulation result shows that the proposed method increases the speed and accuracy of the risk assessment and can provide feasible decision basis for the transformer risk management and maintenance decisions. 展开更多
关键词 fuzzy analytic hierarchy process risk assessment power transformer artificial neutral network
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Comparison of Risk Assessment for a Nuclear Power Plant Construction Project Based on Analytic Hierarchy Process and Fuzzy Analytic Hierarchy Process 被引量:6
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作者 Dae-Woong Shin Yoonseok Shin Gwang-Hee Kim 《Journal of Building Construction and Planning Research》 2016年第3期157-171,共15页
Recently, plant construction throughout the world, including nuclear power plant construction, has grown significantly. The scale of Korea’s nuclear power plant construction in particular, has increased gradually sin... Recently, plant construction throughout the world, including nuclear power plant construction, has grown significantly. The scale of Korea’s nuclear power plant construction in particular, has increased gradually since it won a contract for a nuclear power plant construction project in the United Arab Emirates in 2009. However, time and monetary resources have been lost in some nuclear power plant construction sites due to lack of risk management ability. The need to prevent losses at nuclear power plant construction sites has become more urgent because it demands professional skills and large-scale resources. Therefore, in this study, the Analytic Hierarchy Process (AHP) and Fuzzy Analytic Hierarchy Process (FAHP) were applied in order to make comparisons between decision-making methods, to assess the potential risks at nuclear power plant construction sites. To suggest the appropriate choice between two decision-making methods, a survey was carried out. From the results, the importance and the priority of 24 risk factors, classified by process, cost, safety, and quality, were analyzed. The FAHP was identified as a suitable method for risk assessment of nuclear power plant construction, compared with risk assessment using the AHP. These risk factors will be able to serve as baseline data for risk management in nuclear power plant construction projects. 展开更多
关键词 COMPONENT Analytic Hierarchy process (AHP) Fuzzy Analytic Hierarchy process (FAHP) Nuclear Power Plant Reactor Containment Building (RCB) risk assessment
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Risk Assessment M ode of Sale-Leaseback——Based on Fuzzy Analytic Hierarchy Process 被引量:1
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作者 陈俊宇 李智 张佳煌 《Journal of Donghua University(English Edition)》 EI CAS 2013年第4期343-348,共6页
Sale-leaseback is paid special focus on for its great application in China in recent years.By giving a detailed analysis,an analysis of the features of sale-leaseback and a study of the risks of it are given in this p... Sale-leaseback is paid special focus on for its great application in China in recent years.By giving a detailed analysis,an analysis of the features of sale-leaseback and a study of the risks of it are given in this paper.Then a quantitative analysis of commercial real estate sale-leaseback is carried out.The scientific theoretical analysis is provided in this paper for risk assessment in commercial real estate sale-leaseback mode in China.An effective approach is put forward for sale-leaseback project evaluation and prevention of risk.A useful means is given to supervise commerciai real estate sale-leaseback mode for relevant departments and a certain contribution is made to a further sound development of commercial real estate sale-leaseback mode. 展开更多
关键词 sale-leaseback fuzzy analytic hierarchy process(FAHP) risk assessment modeCLC number:F830.9Document code:AArticle ID:1672-5220(2013)04-0343-06
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Russian and Foreign Experience Review of Territorial Geocryological Hazards Assessment and Risks of Geocryological Processes' Impact
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作者 J.V.Stanilovskaya 《地学前缘》 EI CAS CSCD 北大核心 2009年第S1期76-76,共1页
Hazards and risks assessment of dangerous geocryological processes is actual problem in connection with climate change.Permafrost is widespread in Russia,Canada,the USA(Alaska), China,Mongolia and in mountain regions.... Hazards and risks assessment of dangerous geocryological processes is actual problem in connection with climate change.Permafrost is widespread in Russia,Canada,the USA(Alaska), China,Mongolia and in mountain regions.Currently there are many papers concerning permafrost-related hazards,but the conceptual and based techniques are not available.Different approaches for solving this problem are considered in the paper.The generally accessible techniques of geocryological processes quantitative risk assessment are not available.The problem lies in uncertainty appearing from 展开更多
关键词 hazards and riskS assessment DANGEROUS geocryological processes PERMAFROST
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Risk Assessment and Management of Hazardous Hydrological and Geological Processes in Ukraine
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作者 H. Rudko I. Sumatokhina 《Journal of Agricultural Science and Technology(B)》 2011年第2期232-240,共9页
Due to long and irrational land-utilization, Ukraine deals with one of the most strained ecological situations in Europe. This work is devoted to the study of land resources transformation that was caused by human act... Due to long and irrational land-utilization, Ukraine deals with one of the most strained ecological situations in Europe. This work is devoted to the study of land resources transformation that was caused by human activity. The subject of study is to assess and forecast physical land and soil degradation, associated with the technical intensification of hazardous exogenous processes. The research is based on the use of methods of ecologic-geomorphological analysis, mathematical-statistical modeling and forecasting. This project gives characteristics to the main anthropogenic factors of threats and risks to land and soil, which take place in the territory of Ukraine. The estimation was conducted relatively dangerous hydrological and geological processes that are key factors of physical degradation of resources. These processes include erosion, flooding, secondary waterlogging, landslides and other collapsed phenomena. Graphic models reflect specific factors and environmental consequences of the most dangerous exogenous processes. Predicted is the development of dangerous hydrological and geological processes, influenced by technogenic factors. Different scenarios of physical land degradation are developed by the example of a specific technonatural geosystem. A measurement system of the sustainable usage and management of soil condition in Ukraine is improved. 展开更多
关键词 Threats and risks to land and soil physical degradation of soil hydrogeological and geological processes risk assessment risk management.
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Risk Assessment of Afforestation and Reforestation Processes
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作者 Teodors Blija Anita Blija 《Journal of Agricultural Science and Technology(B)》 2016年第3期196-200,共5页
Relatively simple forest planting process in real life is not so simple. Its relationships with various environmental, climatic, ecological and other environmental conditions cause a lot of problems. In this paper, ha... Relatively simple forest planting process in real life is not so simple. Its relationships with various environmental, climatic, ecological and other environmental conditions cause a lot of problems. In this paper, hazard analysis critical control point (HACCP) analysis was conducted to identify the critical control points in forest regeneration process. As a result, it has a positive effect on the entire reforestation result. Critical control points will enable timely to draw attention to possible errors or incorrect solutions and consequently improve afforestation or restoration quality. Reforestation often occurs mistakes that lead to an unsuccessful reforestation. To remedy this situation, these critical control points should be identified with HAACP analysis. 展开更多
关键词 risk assessment afforestation and reforestation processes critical control points deception of the consumers.
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Risk Assessment of Distributed Energy System Based on Fuzzy Analytic Hierarchy Process
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作者 Chunning Fu 《Journal of Computer and Communications》 2022年第11期56-71,共16页
Risk assessment of distributed energy system often has uncertainty and subjective problems. The problems will have some impact on the results. To solve the problems, a method of improved fuzzy analytic hierarchy proce... Risk assessment of distributed energy system often has uncertainty and subjective problems. The problems will have some impact on the results. To solve the problems, a method of improved fuzzy analytic hierarchy process is proposed. By using the fuzzy analytic hierarchy process method, a hierarchical analysis model is established. And then according to the given judgment matrix of each index layer, we calculate whether it meets the consistency condition. And then if the judgment matrix does not meet the consistency condition, the problem will be solved by the improving of particle swarm optimization (PSO) with Kalman filter. The practice in the distributed energy system shows that the method can not only fully reflect the fuzziness of assessment elements and process, but also reduce the influence of individual subjective factors and better evaluation results can be achieved. 展开更多
关键词 Fuzzy Theory Analytic Hierarchy process Distributed Energy System risk assessment
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Delphi and Analytic hierarchy process for the construction of a risk assessment index system for post-stroke shoulder-hand syndrome
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作者 Yu-Huan Zhang Chun-Bo Fan +3 位作者 Yong-Mei Luo Dong Chen Chun-Xiao Yang Dong Pang 《Nursing Communications》 2022年第1期1-6,共6页
Background:Shoulder-hand syndrome(SHS)is one of the common complications after stroke,which is difficult to cure once it occurs.Early risk identification is an effective measure to prevent and treat SHS,but there is n... Background:Shoulder-hand syndrome(SHS)is one of the common complications after stroke,which is difficult to cure once it occurs.Early risk identification is an effective measure to prevent and treat SHS,but there is no effective tool to assess the risk assessment of SHS.Objective:To develop a validated tool to assess the risk of SHS occurrence after stroke.Methods:This was an observational study with a 3-step process:(1)Literature review to establish initial indicators;(2)Application of a modified Delphi method for two rounds of correspondence,with final indicators obtained by modifying each round based on expert opinion;(3)Application of hierarchical analysis to determine the weights of each indicator.Results:The initial literature review constructed4 primary indicators and 24 secondary indicators;after the first round of Delphi,a total of 10 secondary indicators were deleted and 6 secondary indicators were added,and the final indicators included 3 primary indicators and 15 secondary indicators,and in the second round,consensus was reached;by AHP analysis,the highest weight was given to existing risk factors(0.5584),followed by relevant medical history(0.3196);lastly,demographic factors(0.1220),and the scores of other secondary indicators met the requirements.Conclusion:This study establishes and constructs a post-stroke SHS risk assessment tool,which provides a basis for early identification of SHS and early intervention.Meanwhile,this study provides a methodological reference for the development of other indicatorssets. 展开更多
关键词 Analytic hierarchy process Delphi method Stroke patients Shoulder-hand syndrome Shoulder-hand syndrome risk assessment
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A RISK ASSESSMENT METHOD OF THE WIRELESS NETWORK SECURITY 被引量:13
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作者 Zhao Dongmei Wang Changguang Ma Jianfeng 《Journal of Electronics(China)》 2007年第3期428-432,共5页
The core of network security is the risk assessment. In this letter,a risk assessment method is introduced to estimate the wireless network security. The method,which combines Analytic Hier-archy Process (AHP) method ... The core of network security is the risk assessment. In this letter,a risk assessment method is introduced to estimate the wireless network security. The method,which combines Analytic Hier-archy Process (AHP) method and fuzzy logical method,is applied to the risk assessment. Fuzzy logical method is applied to judge the important degree of each factor in the aspects of the probability,the influence and the uncontrollability,not to directly judge the important degree itself. The risk as-sessment is carved up 3 layers applying AHP method,the sort weight of the third layer is calculated by fuzzy logical method. Finally,the important degree is calculated by AHP method. By comparing the important degree of each factor,the risk which can be controlled by taking measures is known. The study of the case shows that the method can be easily used to the risk assessment of the wireless network security and its results conform to the actual situation. 展开更多
关键词 Wireless network risk assessment Analytic Hierarchy process (AHP) method Fuzzy logical method
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Study of Lightning Damage Risk Assessment Method for Power Grid 被引量:1
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作者 Xiaolan Li Jiahong Chen +1 位作者 Chun Zhao Shanqiang Gu 《Energy and Power Engineering》 2013年第4期1478-1483,共6页
Based on the idea of risk evaluation, the existing lightning damage risk assessment methods are reviewed and summarized in this paper. And the power grid lightning damage risk assessment system is established on the b... Based on the idea of risk evaluation, the existing lightning damage risk assessment methods are reviewed and summarized in this paper. And the power grid lightning damage risk assessment system is established on the basis of lightning flashover risk evaluation methodology for transmission lines, and adopts the improved Analytic Hierarchy Process as the core algorithm. It can comprehensively evaluate the risk for transmission lines of regional grid, various sections of a line and each tower of the section, considering much more impact factors, including the running time of line, importance of grades, equipment damage, and the success rate of lightning stroke reclosing and so on. According to the calculation results of the risk assessment of the analytic hierarchy process and lightning flashover risk evaluation, the principles and methods of grade classification for power grid lightning damage risk map are studied, and give typical examples in the paper. It can describe the lightning withstanding ability much more scientifically and provide important references for the manage department of power system. 展开更多
关键词 POWER Grid LIGHTNING Damage risk assessment ANALYTIC HIERARCHY process LIGHTNING Stroke Trip-out Rate POWER Supply Reliability Transmission Line
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Risk Assessment of Land Subsidence in Kathmandu Valley, Nepal, Using Remote Sensing and GIS 被引量:1
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作者 Richa Bhattarai Akihiko Kondoh 《Advances in Remote Sensing》 2017年第2期132-146,共15页
Land subsidence is identified as a global problem and intensive studies are being conducted worldwide to detect and monitor risk of this problem. Risk assessment of land subsidence is simply an evaluation of the proba... Land subsidence is identified as a global problem and intensive studies are being conducted worldwide to detect and monitor risk of this problem. Risk assessment of land subsidence is simply an evaluation of the probability and frequency of occurrence of land subsidence, exposure of people and property to the subsidence and consequence of that exposure. Remote sensing technology was used to extract information of land subsidence in Kathmandu Valley, Nepal. Also, Disaster Risk Index method and Analytic Hierarchy Process (AHP) along with Geographic Information System (GIS) tools were used to assess risk of land subsidence in Kathmandu Valley, Nepal. Subsidence volume for locations Central Kathmandu, Chauni, Lalitpur, Imadol, Thimi, Madhyaour Thimi, New Baneshwor, Koteshwor and Gothatar was calculated using a simple mathematical formula. The subsidence depth for these locations was found to be in a range of 1 cm to 17 cm and the maximum subsidence velocity was found to be 4.8 cm/yr. This study revealed that the location where maximum subsidence was observed (i.e. Central Kathmandu and Lalitpur) was found to be at high risk of experiencing land subsidence induced damage. Other location where subsidence was observed was found to be at medium risk and the rest of the Kathmandu valley was found to be at low risk with current data situation. This study can be considered as the first step towards other comprehensive study relating to land subsidence risk assessment. The outcome of this research provides a basic understanding of the current situation that can further assist in developing prevention and risk management techniques. 展开更多
关键词 risk assessment of Land SUBSIDENCE HAZARD VULNERABILITY ANALYTIC HIERARCHY process GIS
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Review of Geocryological Hazards and Risks Assessment
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作者 J.V.Stanilovskaya D.O.Sergeev 《地学前缘》 EI CAS CSCD 北大核心 2009年第S1期65-65,共1页
Hazards and risks assessment of dangerous geocryological processes is an actual problem in connection with climate change.Permafrost is widespread in Russia,Canada,the USA(Alaska),China,Mongolia and in mountain region... Hazards and risks assessment of dangerous geocryological processes is an actual problem in connection with climate change.Permafrost is widespread in Russia,Canada,the USA(Alaska),China,Mongolia and in mountain regions.Currently there are many papers concerning permafrost-related hazards,but the conceptual and basic techniques are not available. Different approaches for solving this problem are considered in the paper.The generally accessible techniques of geocryological processes quantitative risk assessment are not available.The problem lies 展开更多
关键词 hazards and riskS assessment DANGEROUS geocryological processES PERMAFROST
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Establishment of a Risk Assessment Framework for Analysis of the Spread of Highly Pathogenic Avian Influenza
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作者 LI Jing WANG Jing-fei +3 位作者 WU Chun-yan YANG Yan-tao JI Zeng-tao WANG Hong-bin 《Agricultural Sciences in China》 CAS CSCD 2007年第7期877-881,共5页
To evaluate the risk of highly pathogenic avian influenza (HPAI) in China's Mainland, a risk assessment framework was built. Risk factors were determined by analyzing the epidemic data using the brainstorming me... To evaluate the risk of highly pathogenic avian influenza (HPAI) in China's Mainland, a risk assessment framework was built. Risk factors were determined by analyzing the epidemic data using the brainstorming method; the analytic hierarchy process was designed to weigh risk factors, and the integrated multicriteria analysis was used to evaluate the final result. The completed framework included the risk factor system, data standards for risk factors, weights of risk factors, and integrated assessment methods. This risk assessment framework can be used to quantitatively analyze the outbreak and spread of HPAI in China's Mainland. 展开更多
关键词 highly pathogenic avian influenza (HPAI) risk factor risk assessment framework analytical hierarchy process (AHP) WEIGHTS integrated assessment
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Current Lightning Risk Assessment in Yantai
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作者 Zhang Zheng Zhou Fengyun Xu Lijun 《Meteorological and Environmental Research》 CAS 2014年第1期49-50,54,共3页
The development situation and business processes of lightning risk assessment in Yantai were summarized and analyzed to provide references for the operation of lighting risk assessment. This study aimed to further imp... The development situation and business processes of lightning risk assessment in Yantai were summarized and analyzed to provide references for the operation of lighting risk assessment. This study aimed to further improve lightning risk assessment and promote the development of lightning risk assessment through practice and discussion. 展开更多
关键词 Lightning risk assessment Current status Business processes Yantai China
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A Fuzzy Logic-Based Method for Risk Assessment of Bridges during Construction
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作者 Jin Cheng Mingsai Xu Zhengrong Chen 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2019年第1期1-10,共10页
There are many potential sources of risks which may cause bridge failures and result in numerous economic and human losses during the construction of bridges. Therefore,risk assessment for bridges during construction ... There are many potential sources of risks which may cause bridge failures and result in numerous economic and human losses during the construction of bridges. Therefore,risk assessment for bridges during construction should be taken rigorously to avert bridge failures and casualties. This article presents a fuzzy logic-based method which integrates the fuzzy analytical hierarchy process( FAHP) method based on a 3-point scale,fuzzy logic,and fuzzy set theory into a single synthetic method. In this method,the FAHP method based on a 3-point scale was used to identify and rank diverse risk factors,and fuzzy logic and fuzzy set theory were used to process inaccurate datasets including non-statistical information. After the concept and procedure of the FAHP method based on a 3-point scale were demonstrated,the proposed fuzzy logic-based method was used to perform risk assessment on the Aizhai Suspension Bridge with a main span length of1 176 m in China. The results show that the proposed method can more effectively carry out risk assessment of bridges during construction. 展开更多
关键词 analytical hierarchy process risk assessment fuzzy logic fuzzy consistent matrix bridge construction
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Fuzzy Risk Assessment Model of Power Transformer Based on Borda Number Theory
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作者 WANG You-yuan YUAN Yuan LI Jian DU Lin ZHOU Jing-jing 《高电压技术》 EI CAS CSCD 北大核心 2008年第12期2668-2673,共6页
The power transformer is the key equipment of transforming voltage and exchanging power in the power system.It's safe and reliable operation directly influences the safe level of the power system.To study the risk... The power transformer is the key equipment of transforming voltage and exchanging power in the power system.It's safe and reliable operation directly influences the safe level of the power system.To study the risk assessment of power transformer which is very significant to improve the reliability of the power system,a fuzzy comprehensive risk assessment model of power transformer based on Borda number theory is proposed in this paper.At first,the fault types and risk factors of the power transformer are analyzed.Secondly,the basic framework of the fuzzy comprehensive evaluation is applied to quantify the risk factors.And then,Borda number theory is employed to analyze influence degree and occurrence probability of power transformer.At last,the various risk factors impact index and fuzzy comprehensive evaluation index of power transformer can be easily obtained.Applying this model,the relative importance degree of the risk factors can be horizontally compared according to the numerical index,the engineering staff can directly get the parameters of the transformer risk level and get a good description of the visual expression through using 5 score and similar visual language. 展开更多
关键词 模糊风险评估模型 Borda数理论 电力变压器 故障树结构
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Research on Risk Assessment Method of Long-Tube Trailer Road Transportation
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作者 Caiyan Dai Wenkun Wang +4 位作者 Ming Xu Chenglong Ma Lianqing Yang Hong Zhao Yuan He 《Journal of Software Engineering and Applications》 2023年第8期420-441,共22页
Road transport safety has always been paid attention to by the safety production managers of enterprises. In this study, cloud model and analytic hierarchy process were applied to the safety of long-tube trailer trans... Road transport safety has always been paid attention to by the safety production managers of enterprises. In this study, cloud model and analytic hierarchy process were applied to the safety of long-tube trailer transport. The opinions of 30 experts were analyzed, from which 29 key parameters were selected. The study addressed the relevance of the parameters and the possibility of automatic collection and transmission to obtain 12 core risk factors. The macro-safety risk indicator system for long-tube trailers was established based on the identified risk indicators. Finally, a risk assessment model for road transport of long tube trailers consisting of 3 dimensions of likelihood, severity and sensitivity was constructed. This model provides a technical method for strengthening the risk control of road transport of long-tube trailers. 展开更多
关键词 Cloud Model Analytic Hierarchy process Long-Tube Trailer risk Factors risk assessment Model
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A strategy for population pharmaceutical quality assessment based on quality by design 被引量:2
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作者 Yu Zhao Changqin Hu +2 位作者 Shangchen Yao Lihui Yin Xiaomei Ling 《Journal of Pharmaceutical Analysis》 SCIE CAS CSCD 2021年第5期588-595,共8页
From a regulatory perspective,drug quality consistency evaluation must concern different processes used for the same drug.In this study,an assessment strategy based on quality by design(QbD)was developed for populatio... From a regulatory perspective,drug quality consistency evaluation must concern different processes used for the same drug.In this study,an assessment strategy based on quality by design(QbD)was developed for population pharmaceutical quality evaluation.A descriptive analysis method based on QbD concept was first established to characterize the process by critical evaluation attributes(CEAs).Then quantitative analysis method based on an improved statistical process control(SPC)method was established to investigate the process indicators(PIs)in the process population,such as mean distribution,batch-to-batch difference and abnormal quality probability.After that rules for risk assessment were established based on the SPC limitations and parameters.Both the SPC parameters of the CEAs and the risk of PIs were visualized according to the interaction test results to obtain a better understanding of the population pharmaceutical quality.Finally,an assessment strategy was built and applied to generic drug consistency assessment,process risk assessment and quality trend tracking.The strategy demonstrated in this study could help reveal quality consistency from the perspective of process control and process risk,and further show the recent development status of domestic pharmaceutical production processes.In addition,a process risk assessment and population quality trend tracking provide databased information for approval.Not only can this information serve as a further basis for decisionmaking by the regulatory authority regarding early warnings,but it can also reduce some avoidable adverse reactions.With continuous addition of data,dynamic population pharmaceutical quality is meaningful for emergencies and decision-making regarding drug regulation. 展开更多
关键词 Population pharmaceutical quality Quality by design(QbD) Crucial evaluation attributes(CEAs) process indicators(PIs) Improved statistical process control(SPC) risk assessment
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