The plants of Orchidaceae are widely distributed in the world,47 species of which have been used as folk medicines with a long history.The tubers and stems of them exhibit diverse efficacy,including clearing heat and ...The plants of Orchidaceae are widely distributed in the world,47 species of which have been used as folk medicines with a long history.The tubers and stems of them exhibit diverse efficacy,including clearing heat and resolving toxin,moistening lung and relieving cough and promoting blood circulation.Since dihydrophenanthrenes were responsible for the medical purposes,the characteristic skeletons,pharmacological effects and clinical applications of dihydrophenanthrenes were summarized in this review,so as to provide a theoretical basis for the comprehensive study,development and application of DPs from medicinal plants of Orchidaceae.展开更多
To study the chemical constituents in Bletilla ochracea Schltr. , repeated column chromatographies and preparative TLC were used for the isolation of compounds, and spectroscopic techniques (NMR, IR, UV and MS) were...To study the chemical constituents in Bletilla ochracea Schltr. , repeated column chromatographies and preparative TLC were used for the isolation of compounds, and spectroscopic techniques (NMR, IR, UV and MS) were used for their structural identification. Seven compounds, 2,7-bis ( allyloxy ) -5-methoxy-3-methyl-9, 10-dihydrophenanthrene(1), gastrodin(2), gastrodigenin(3), β-sitosterol(4), stigmasterol(5), 4-hydroxybernzaldehyde(6), and daucosterol(7) were obtained from the roots of B. ochracea Schltr. Compound 1 is structurally illustrated as a novel compound, and the others are isolated from the title plant for the first time.展开更多
基金financially supported by National Natural Science Foundation of China(No.81872768,82003630,U1603125)Liaoning Revitalization Talents Program(No.XLYC1807118)+2 种基金Shenyang Young Scientific and Technological Innovators Programme(No.RC200408)Doctoral Scientific Research Foundation of Liaoning Province(No.2020-BS-129)Special Fund of Research Institute of Drug Regulatory Science Research Shenyang Pharmaceutical University(No.2021jgkx010)。
文摘The plants of Orchidaceae are widely distributed in the world,47 species of which have been used as folk medicines with a long history.The tubers and stems of them exhibit diverse efficacy,including clearing heat and resolving toxin,moistening lung and relieving cough and promoting blood circulation.Since dihydrophenanthrenes were responsible for the medical purposes,the characteristic skeletons,pharmacological effects and clinical applications of dihydrophenanthrenes were summarized in this review,so as to provide a theoretical basis for the comprehensive study,development and application of DPs from medicinal plants of Orchidaceae.
文摘To study the chemical constituents in Bletilla ochracea Schltr. , repeated column chromatographies and preparative TLC were used for the isolation of compounds, and spectroscopic techniques (NMR, IR, UV and MS) were used for their structural identification. Seven compounds, 2,7-bis ( allyloxy ) -5-methoxy-3-methyl-9, 10-dihydrophenanthrene(1), gastrodin(2), gastrodigenin(3), β-sitosterol(4), stigmasterol(5), 4-hydroxybernzaldehyde(6), and daucosterol(7) were obtained from the roots of B. ochracea Schltr. Compound 1 is structurally illustrated as a novel compound, and the others are isolated from the title plant for the first time.