Dip-pen nanolithography is a new scanning probe lithography (SPL) technique based on atomic force microscopy (AFM), and now has made a great progress. The process of dip-pen lithography involves the adsorption of ink ...Dip-pen nanolithography is a new scanning probe lithography (SPL) technique based on atomic force microscopy (AFM), and now has made a great progress. The process of dip-pen lithography involves the adsorption of ink molecules on AFM tip, the formation of water meniscus, the transport of ink molecules, and diffusion of ink molecules on the substrate. More factors such as temperature, humidity, tip, scanning speed and so on will influence the process of dip-pen lithography. The paper analyzes in detail the mechanism of this technique, introduces synthetically the latest development, including electrochemical DPN, more-mode DPN, multiple DPN, multi-probe array DPN and so on. Finally, the paper describes the characteristics and the application of DPN.展开更多
Dip-pen nanolithography is an emerging and attractive surface modification technique that has the capacity to directly and controllably write micro/nano-array patterns on diverse substrates.The superior throughput,res...Dip-pen nanolithography is an emerging and attractive surface modification technique that has the capacity to directly and controllably write micro/nano-array patterns on diverse substrates.The superior throughput,resolution,and registration enable DPN an outstanding candidate for biological detection from the molecular level to the cellular level.Herein,we overview the technological evolution of DPN in terms of its advanced derivatives and DPN-enabled versatile sensing patterns featuring multiple compositions and structures for biosensing.Benefitting from uniform,reproducible,and large-area array patterns,DPN-based biosensors have shown high sensitivity,excellent selectivity,and fast response in target analyte detection and specific cellular recognition.We anticipate that DPN-based technologies could offer great potential opportunities to fabricate multiplexed,programmable,and commercial array-based sensing biochips.展开更多
Dip-pen na.nolithography （DPN） is a useful method for directly printing materials on surfaces with sub-50nm resolution. Because it, involves the physical transport of materials from a scanning probe tip to a surface...Dip-pen na.nolithography （DPN） is a useful method for directly printing materials on surfaces with sub-50nm resolution. Because it, involves the physical transport of materials from a scanning probe tip to a surface and the subsequent chemical interaction of that material with the surface, there are many factors to consider when attempting to understand DPN. In this review, we overview the physical and chemical processes that are known to play a role in DPN, Through a detailed review of the literature, we classify inks into three general categories based on their transport properties, and highlight the myriad ways that. DPN can be used to perform chemistry at the tip of a scanning probe.展开更多
基金Foundation of Education of Zhejiang Province, China ( No.20060470).
文摘Dip-pen nanolithography is a new scanning probe lithography (SPL) technique based on atomic force microscopy (AFM), and now has made a great progress. The process of dip-pen lithography involves the adsorption of ink molecules on AFM tip, the formation of water meniscus, the transport of ink molecules, and diffusion of ink molecules on the substrate. More factors such as temperature, humidity, tip, scanning speed and so on will influence the process of dip-pen lithography. The paper analyzes in detail the mechanism of this technique, introduces synthetically the latest development, including electrochemical DPN, more-mode DPN, multiple DPN, multi-probe array DPN and so on. Finally, the paper describes the characteristics and the application of DPN.
文摘Dip-pen nanolithography is an emerging and attractive surface modification technique that has the capacity to directly and controllably write micro/nano-array patterns on diverse substrates.The superior throughput,resolution,and registration enable DPN an outstanding candidate for biological detection from the molecular level to the cellular level.Herein,we overview the technological evolution of DPN in terms of its advanced derivatives and DPN-enabled versatile sensing patterns featuring multiple compositions and structures for biosensing.Benefitting from uniform,reproducible,and large-area array patterns,DPN-based biosensors have shown high sensitivity,excellent selectivity,and fast response in target analyte detection and specific cellular recognition.We anticipate that DPN-based technologies could offer great potential opportunities to fabricate multiplexed,programmable,and commercial array-based sensing biochips.
基金Acknowledgements C.A.M. acknowledges the U. S. Air Force Office of Scientific Research （AFOSR, Awards FA9550-12-1-0280 and FA9550-12-1-0141）, the Defense Advanced Research Projects Agency （DARPA, Award N66001-08-1-2044） and the National Science Foundation （NSF, Awards DBI-1152139 and DMB-1124131） for support of this research. K. A. B. and X. L. gratefully acknowledges support from Northwestern University＇s International Institute for Nanotechnology. D. J. E. acknowledges the DoD and AFOSR for a National Defense Science and Engineering Graduate （NDSEG） Fellowship, 32 CFR 168a.
文摘Dip-pen na.nolithography （DPN） is a useful method for directly printing materials on surfaces with sub-50nm resolution. Because it, involves the physical transport of materials from a scanning probe tip to a surface and the subsequent chemical interaction of that material with the surface, there are many factors to consider when attempting to understand DPN. In this review, we overview the physical and chemical processes that are known to play a role in DPN, Through a detailed review of the literature, we classify inks into three general categories based on their transport properties, and highlight the myriad ways that. DPN can be used to perform chemistry at the tip of a scanning probe.
