It was found for the first time that the compounds with only one functional group, such as pyridine, can show the promotion effect for the electrochemical reaction of cytochrome C at gold electrodes.
Autophagy dysfunction is a common feature in neurodegenerative disorders caused by the accumulation of toxic,aggregate-prone proteins.Increasing evidence have demonstrated that genetic or pharmacological activation of...Autophagy dysfunction is a common feature in neurodegenerative disorders caused by the accumulation of toxic,aggregate-prone proteins.Increasing evidence have demonstrated that genetic or pharmacological activation of transcription factor EB(TFEB),a master regulator of autophagy and lysosomal biogenesis,ameliorates neurotoxicity and rescues neurodegenerative phenotypes in several animal models of neurodegenerative diseases.展开更多
基金The project is supported by National Natural Science Foundation of China
文摘It was found for the first time that the compounds with only one functional group, such as pyridine, can show the promotion effect for the electrochemical reaction of cytochrome C at gold electrodes.
文摘Autophagy dysfunction is a common feature in neurodegenerative disorders caused by the accumulation of toxic,aggregate-prone proteins.Increasing evidence have demonstrated that genetic or pharmacological activation of transcription factor EB(TFEB),a master regulator of autophagy and lysosomal biogenesis,ameliorates neurotoxicity and rescues neurodegenerative phenotypes in several animal models of neurodegenerative diseases.
