Direct coaptation of contralateral C7 to the upper trunk could avoid the interposition of nerve grafts. We have successfully shortened the gap and graft lengths, and even achieved direct coaptation. However, direct re...Direct coaptation of contralateral C7 to the upper trunk could avoid the interposition of nerve grafts. We have successfully shortened the gap and graft lengths, and even achieved direct coaptation. However, direct repair can only be performed in some selected cases, and partial procedures still require autografts, which are the gold standard for repairing neurologic defects. As symptoms often occur after autografting, human acellular nerve allografts have been used to avoid concomitant symptoms. This study investigated the quality of shoulder abduction and elbow flexion following direct repair and acellular allografting to evaluate issues requiring attention for brachial plexus injury repair. Fifty-one brachial plexus injury patients in the surgical database were eligible for this retrospective study. Patients were divided into two groups according to different surgical methods. Direct repair was performed in 27 patients, while acellular nerve allografts were used to bridge the gap between the contralateral C7 nerve root and upper trunk in 24 patients. The length of the harvested contralateral C7 nerve root was measured intraoperatively. Deltoid and biceps muscle strength, and degrees of shoulder abduction and elbow flexion were examined according to the British Medical Research Council scoring system;meaningful recovery was defined as M3–M5. Lengths of anterior and posterior divisions of the contralateral C7 in the direct repair group were 7.64 ± 0.69 mm and 7.55 ± 0.69 mm, respectively, and in the acellular nerve allografts group were 6.46 ± 0.58 mm and 6.43 ± 0.59 mm, respectively. After a minimum of 4-year follow-up, meaningful recoveries of deltoid and biceps muscles in the direct repair group were 88.89% and 85.19%, respectively, while they were 70.83% and 66.67% in the acellular nerve allografts group. Time to C5/C6 reinnervation was shorter in the direct repair group compared with the acellular nerve allografts group. Direct repair facilitated the restoration of shoulder abduction and elbow flexion. Thus, if direct coaptation is not possible, use of acellular nerve allografts is a suitable option. This study was approved by the Medical Ethical Committee of the First Affiliated Hospital of Sun Yat-sen University, China (Application ID:[2017] 290) on November 14, 2017.展开更多
Measurements of wave heights with image sequences from a Charged Coupled Device(CCD) camera were made. Sinusoidal, as well as unidirectional and directional, waves were used for the experiments. A transfer function wa...Measurements of wave heights with image sequences from a Charged Coupled Device(CCD) camera were made. Sinusoidal, as well as unidirectional and directional, waves were used for the experiments. A transfer function was obtained by calibration of the magnitudes of the gray values of the images against the results of wave gauge measurements for directional waves. With this transfer function, wave heights for regular waves were deduced. It is shown that the average relative errors are smaller than 16% for both unidirectional and directional waves.展开更多
将网络信息的概念引入到神经科学当中对于研究脑功能机制有着积极的作用。然而人脑网络的复杂性对于理解有一定的困难。该文基于有向传递函数(Directed Transfer Function,DTF)的方法估计得到功能连接模式,进一步提出了信息流增益的计...将网络信息的概念引入到神经科学当中对于研究脑功能机制有着积极的作用。然而人脑网络的复杂性对于理解有一定的困难。该文基于有向传递函数(Directed Transfer Function,DTF)的方法估计得到功能连接模式,进一步提出了信息流增益的计算方法,用以评价特定脑区在全脑信息传输过程中的作用。该方法将流入信息和流出信息结合,具有浓缩两者信息的优点,简化了脑复杂网络的辨识度,并且提高了结果的显示标度。仿真运算和自发、诱发脑电数据的结果都显示出通过计算分析信息流增益可以比较理想地得到各个脑区对全脑信息流的贡献。结果证明信息流增益方法为进一步理解大脑认知机制提供了可能。展开更多
基金supported by the National Natural Science Foundation of China,No.81572130(to LQG)and 81601057(to JTY)the National Key Research and Development Plan of China,No.2016YFC1101603(to XLL)the Natural Science Foundation of Guangdong Province of China,No.2015A030310350(to JTY)
文摘Direct coaptation of contralateral C7 to the upper trunk could avoid the interposition of nerve grafts. We have successfully shortened the gap and graft lengths, and even achieved direct coaptation. However, direct repair can only be performed in some selected cases, and partial procedures still require autografts, which are the gold standard for repairing neurologic defects. As symptoms often occur after autografting, human acellular nerve allografts have been used to avoid concomitant symptoms. This study investigated the quality of shoulder abduction and elbow flexion following direct repair and acellular allografting to evaluate issues requiring attention for brachial plexus injury repair. Fifty-one brachial plexus injury patients in the surgical database were eligible for this retrospective study. Patients were divided into two groups according to different surgical methods. Direct repair was performed in 27 patients, while acellular nerve allografts were used to bridge the gap between the contralateral C7 nerve root and upper trunk in 24 patients. The length of the harvested contralateral C7 nerve root was measured intraoperatively. Deltoid and biceps muscle strength, and degrees of shoulder abduction and elbow flexion were examined according to the British Medical Research Council scoring system;meaningful recovery was defined as M3–M5. Lengths of anterior and posterior divisions of the contralateral C7 in the direct repair group were 7.64 ± 0.69 mm and 7.55 ± 0.69 mm, respectively, and in the acellular nerve allografts group were 6.46 ± 0.58 mm and 6.43 ± 0.59 mm, respectively. After a minimum of 4-year follow-up, meaningful recoveries of deltoid and biceps muscles in the direct repair group were 88.89% and 85.19%, respectively, while they were 70.83% and 66.67% in the acellular nerve allografts group. Time to C5/C6 reinnervation was shorter in the direct repair group compared with the acellular nerve allografts group. Direct repair facilitated the restoration of shoulder abduction and elbow flexion. Thus, if direct coaptation is not possible, use of acellular nerve allografts is a suitable option. This study was approved by the Medical Ethical Committee of the First Affiliated Hospital of Sun Yat-sen University, China (Application ID:[2017] 290) on November 14, 2017.
基金This work was financially supported by the Science Council, Taiwan (Project No. NSC 91 2611 E 019 007)
文摘Measurements of wave heights with image sequences from a Charged Coupled Device(CCD) camera were made. Sinusoidal, as well as unidirectional and directional, waves were used for the experiments. A transfer function was obtained by calibration of the magnitudes of the gray values of the images against the results of wave gauge measurements for directional waves. With this transfer function, wave heights for regular waves were deduced. It is shown that the average relative errors are smaller than 16% for both unidirectional and directional waves.
文摘将网络信息的概念引入到神经科学当中对于研究脑功能机制有着积极的作用。然而人脑网络的复杂性对于理解有一定的困难。该文基于有向传递函数(Directed Transfer Function,DTF)的方法估计得到功能连接模式,进一步提出了信息流增益的计算方法,用以评价特定脑区在全脑信息传输过程中的作用。该方法将流入信息和流出信息结合,具有浓缩两者信息的优点,简化了脑复杂网络的辨识度,并且提高了结果的显示标度。仿真运算和自发、诱发脑电数据的结果都显示出通过计算分析信息流增益可以比较理想地得到各个脑区对全脑信息流的贡献。结果证明信息流增益方法为进一步理解大脑认知机制提供了可能。
